Page last updated: 2024-08-22

camptothecin and lamellarin d

camptothecin has been researched along with lamellarin d in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Bailly, C; Gago, F; Ishibashi, F; Iwao, M; Laine, W; Lansiaux, A; Marco, E; Tardy, C1
Baldeyrou, B; Bourg, S; Buron, F; Lansiaux, A; Lozach, O; Meijer, L; Mérour, JY; Neagoie, C; Rosca, S; Routier, S; Vedrenne, E1
Durieu, E; Fukuda, T; Ishibashi, F; Itoyama, R; Iwao, M; Loaëc, N; Lozach, O; Meijer, L; Tanaka, J; Yamahira, M; Yoshida, K1
Fujimoto, M; Fukuda, T; Ishibashi, F; Iwao, M; Nanjo, Y; Natsui, Y; Okazaki, F; To, H; Yoshida, K1
Goon, S; Kundu, B; Mondal, MA; Sarkar, D; Talukdar, A1
Bailly, C; Beauvillain, JC; Cuevas, C; Gallego, MA; Kluza, J; Loyens, A; Marchetti, P; Sousa-Faro, JM1
Agama, K; Lorence, N; Neuman, KC; Pommier, Y; Seol, Y; Zhang, H1
Collin, S; Criscuolo, A; Dahmane, N; Delmas, S; Desnoues, N; Eberhard, S; Forterre, P; Gadelle, D; Pommier, Y; Sezonov, G; Zhang, H1

Reviews

1 review(s) available for camptothecin and lamellarin d

ArticleYear
Topoisomerase I inhibitors: Challenges, progress and the road ahead.
    European journal of medicinal chemistry, 2022, Jun-05, Volume: 236

    Topics: Antineoplastic Agents; Camptothecin; DNA Topoisomerases, Type I; Irinotecan; Poisons; Topoisomerase I Inhibitors

2022

Other Studies

7 other study(ies) available for camptothecin and lamellarin d

ArticleYear
Molecular determinants of topoisomerase I poisoning by lamellarins: comparison with camptothecin and structure-activity relationships.
    Journal of medicinal chemistry, 2005, Jun-02, Volume: 48, Issue:11

    Topics: Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Computer Simulation; Coumarins; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Heterocyclic Compounds, 4 or More Rings; Humans; Intercalating Agents; Isoquinolines; Models, Molecular; Protein Binding; Structure-Activity Relationship; Thermodynamics; Topoisomerase I Inhibitors

2005
Synthesis of chromeno[3,4-b]indoles as Lamellarin D analogues: a novel DYRK1A inhibitor class.
    European journal of medicinal chemistry, 2012, Volume: 49

    Topics: Coumarins; DNA Topoisomerases, Type I; Dyrk Kinases; Heterocyclic Compounds, 4 or More Rings; Humans; Indoles; Isoquinolines; Models, Molecular; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Structure-Activity Relationship; Topoisomerase I Inhibitors

2012
Synthesis, resolution, and biological evaluation of atropisomeric (aR)- and (aS)-16-methyllamellarins N: unique effects of the axial chirality on the selectivity of protein kinases inhibition.
    Journal of medicinal chemistry, 2013, Sep-26, Volume: 56, Issue:18

    Topics: Antineoplastic Agents; Cell Line, Tumor; Chemistry Techniques, Synthetic; DNA Topoisomerases, Type I; Humans; Molecular Docking Simulation; Polycyclic Compounds; Protein Conformation; Protein Kinase Inhibitors; Protein Kinases; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity; Topoisomerase I Inhibitors

2013
Lamellarin-inspired potent topoisomerase I inhibitors with the unprecedented benzo[g][1]benzopyrano[4,3-b]indol-6(13H)-one scaffold.
    Bioorganic & medicinal chemistry, 2019, 01-15, Volume: 27, Issue:2

    Topics: Animals; Antineoplastic Agents; Cattle; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Coumarins; Drug Design; Drug Screening Assays, Antitumor; Humans; Indoles; Male; Mice, Inbred BALB C; Molecular Structure; Structure-Activity Relationship; Topoisomerase I Inhibitors

2019
Cancer cell mitochondria are direct proapoptotic targets for the marine antitumor drug lamellarin D.
    Cancer research, 2006, Mar-15, Volume: 66, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Camptothecin; Cell Line, Tumor; Cell Membrane Permeability; Cell-Free System; Coumarins; Cytochromes c; Heterocyclic Compounds, 4 or More Rings; Humans; Isoquinolines; Leukemia P388; Lung Neoplasms; Membrane Potentials; Mice; Mitochondria; Mitochondrial Membranes; NIH 3T3 Cells; Rats

2006
Single-Molecule Supercoil Relaxation Assay as a Screening Tool to Determine the Mechanism and Efficacy of Human Topoisomerase IB Inhibitors.
    Molecular cancer therapeutics, 2015, Volume: 14, Issue:11

    Topics: Antineoplastic Agents; Benzodioxoles; Camptothecin; Cell Line, Tumor; Cell Proliferation; Coumarins; DNA Cleavage; DNA Topoisomerases, Type I; DNA, Superhelical; Heterocyclic Compounds, 4 or More Rings; Humans; Inhibitory Concentration 50; Isoquinolines; Kinetics; Molecular Structure; Nucleic Acid Conformation; Substrate Specificity; Topoisomerase I Inhibitors

2015
topIb, a phylogenetic hallmark gene of Thaumarchaeota encodes a functional eukaryote-like topoisomerase IB.
    Nucleic acids research, 2016, Apr-07, Volume: 44, Issue:6

    Topics: Amino Acid Sequence; Archaea; Archaeal Proteins; Camptothecin; Cloning, Molecular; Coumarins; DNA Topoisomerases, Type I; DNA, Superhelical; Escherichia coli; Gene Expression; Heterocyclic Compounds, 4 or More Rings; Hot Temperature; Humans; Isoquinolines; Mitochondrial Proteins; Models, Molecular; Molecular Sequence Data; Phylogeny; Protein Stability; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Topoisomerase I Inhibitors

2016