camptothecin has been researched along with lactic acid in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (4.08) | 18.2507 |
| 2000's | 8 (16.33) | 29.6817 |
| 2010's | 39 (79.59) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Burke, TG; Schwendeman, SP; Shenderova, A | 1 |
| Ertl, B; Gabor, F; Platzer, P; Wirth, M | 1 |
| Machida, Y; Miura, H; Onishi, H; Sasatsu, M | 1 |
| Dadashzadeh, S; Derakhshandeh, K; Erfan, M | 1 |
| Kunii, R; Machida, Y; Onishi, H | 1 |
| Luan, LB; Wu, QL | 1 |
| Chang, GT; Ding, JD; Yu, L; Zhang, H | 1 |
| Koyama, K; Kunii, R; Machida, Y; Onishi, H; Ueki, K | 1 |
| Chapman, GH; Dykes, J; Häfeli, UO; Jackson, JK; Schneider, T; Zhao, H | 1 |
| Burden, RE; Fay, F; Marouf, WM; McCarron, PA; Olwill, SA; Quinn, DJ; Scott, CJ | 1 |
| Atyabi, F; Azizi, E; Dinarvand, R; Ebrahimnejad, P; Jaafari, MR; Nomani, AR; Rad-Malekshahi, M; Sajadi, A | 1 |
| Bae, SM; Jeong, SY; Kim, IS; Kim, JH; Kim, K; Kim, MS; Kwon, IC; Lee, DS; Lee, H; Min, KH; Park, RW; Park, S; Shin, H | 1 |
| Du, YZ; Hu, FQ; Wang, L; Yuan, H; Zhou, JP; Zhou, YY | 1 |
| Hashizawa, K; Imai, Y; Kaneko, D; Okada, H; Ozeki, T | 1 |
| Allard, E; Benoit, JP; Bilensoy, E; Calış, S; Cırpanlı, Y; Lemaire, L; Passirani, C | 1 |
| Dadashzadeh, S; Derakhshandeh, K; Saghiri, R; Soheili, M | 1 |
| Atyabi, F; Dinarvand, R; Ebrahimnejad, P; Jafari, MR; Tabasi, SA | 1 |
| Bilensoy, E; Calis, S; Cirpanli, Y; Dogan, AL | 1 |
| Ainslie, KM; Bachelder, EM; Kanthamneni, N; Kauffman, KJ; Kim, YJ; Meenach, SA | 1 |
| Hashizawa, K; Imai, Y; Kaneko, D; Okada, H; Ozeki, T; Tagami, T | 2 |
| Deepagan, VG; Jayasree, A; Koyakutty, M; Menon, D; Nair, SV; Nascimento, A; Rangasamy, J; Sarmento, B; Sreeranganathan, M | 1 |
| Amna, T; Barakat, NA; Bing, YY; Hassan, MS; Khil, MS; Kim, HY; Nam, KT | 1 |
| Hu, CM; Jin, S; Kong, SD; Sartor, M; Zhang, L; Zhang, W | 1 |
| Ding, LY; Guo, M; Liu, YQ; Lu, Y; Ron, WT; Song, FF; Wang, Y; Yu, SQ | 1 |
| Calis, S; Dimchevska, S; Geskovski, N; Goracinova, K; Kajdžanoska, M; Kuzmanovska, S; Petruševski, G; Simonoska Crcarevska, M; Ugarkovic, S | 1 |
| Guo, M; Hou, J; Lu, Y; Rong, WT; Wang, DF; Wang, Y; Xu, Q; Yu, SQ | 1 |
| Han, MY; Jiang, S; Teng, CP; Win, KY; Ye, E | 1 |
| Dishman, AF; Lahann, J; Park, TH; Rahmani, S | 1 |
| Atyabi, F; Dinarvand, R; Ghahremani, MH; Khoshayand, MR; Montazeri, H; Ostad, SN; Rouhani, H; Sepehri, N; Tavassolian, F | 1 |
| Deng, Y; Ediriwickrema, A; Saltzman, WM; Zhou, J | 1 |
| Ding, GB; Guo, Y; Wang, Y; Xu, L | 1 |
| Berens, ME; Chung, EP; Dhruv, HD; DiPerna, DM; Householder, KT; Sirianni, RW; Wohlleb, GM | 1 |
| Hou, J; Lu, Y; Qi, SS; Rong, WT; Wang, DF; Xiao, Q; Xu, Q; You, J; Yu, SQ; Zhang, J | 1 |
| Chen, L; Cheng, X; Liu, H; Qiu, N; Wang, W; Wang, Z; Wen, J; Yang, J | 1 |
| Agarwal, P; He, X; Lu, X; Wang, H; Xu, RX; Yu, J; Zhao, S | 1 |
| Daoud, J; Essa, S; Lafleur, M; Martel, S; Tabrizian, M | 1 |
| Han, MK; Merlin, D; Si, X; Viennois, E; Wang, L; Xiao, B; Zhang, M | 1 |
| Ambrosio, L; Biondi, M; Borzacchiello, A; De Rosa, G; Giarra, S; Mayol, L; Russo, L; Serri, C; Zeppetelli, S | 1 |
| Amini, M; Atyabi, F; Baharian, A; Dinarvand, R; Ghahremani, MH; Gharghabi, M; Mehdizadeh, M; Ostad, SN; Rouhani, H; Sepehri, N; Varshochian, R | 1 |
| Han, L; Li, R; Qing, J; Qiu, M; Ru, G; Sheng, J; Wang, J | 1 |
| Bo, X; Chen, H; He, Y; Li, D; Li, P; Li, X; Xu, H; Zhang, K | 1 |
| Huang, YC; Lee, WH; Liu, SC; Liu, SJ; Su, CH; Tseng, YY; Wang, YC; Yang, ST | 1 |
| Ci, T; Cui, S; Ding, J; Liu, R; Shen, Y; Yu, L | 1 |
| Emami, J; Hasanzadeh, F; Maghzi, P; Mirian, M; Rostami, M; Sadeghi, H | 1 |
| Gao, Z; Li, Z; Wang, P; Yan, J | 1 |
| Ahmad, N; Ahmad, R; Alam, MA; Jalees Ahmad, F; Umar, S | 1 |
| Chang, D; Han, D; Hou, ZQ; Xie, LY; Yang, XR | 1 |
49 other study(ies) available for camptothecin and lactic acid
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Stabilization of 10-hydroxycamptothecin in poly(lactide-co-glycolide) microsphere delivery vehicles.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Delayed-Action Preparations; Drug Stability; Lactic Acid; Microscopy, Confocal; Microscopy, Electron, Scanning; Microspheres; Molecular Weight; Pharmaceutical Vehicles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 1997 |
Poly(D,L-lactic-co-glycolic acid) microspheres for sustained delivery and stabilization of camptothecin.
Topics: Antineoplastic Agents, Phytogenic; Biocompatible Materials; Camptothecin; Delayed-Action Preparations; Drug Stability; Kinetics; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 1999 |
Antitumor characteristics of methoxypolyethylene glycol-poly(DL-lactic acid) nanoparticles containing camptothecin.
Topics: Animals; Antineoplastic Agents; Camptothecin; Lactic Acid; Male; Mice; Nanostructures; Polyethylene Glycols; Rats; Rats, Wistar; Sarcoma 180 | 2004 |
Encapsulation of 9-nitrocamptothecin, a novel anticancer drug, in biodegradable nanoparticles: factorial design, characterization and release kinetics.
Topics: Antineoplastic Agents; Biocompatible Materials; Calorimetry, Differential Scanning; Camptothecin; Drug Compounding; Drug Delivery Systems; Lactic Acid; Microscopy, Electron, Scanning; Models, Theoretical; Molecular Structure; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Research Design; Technology, Pharmaceutical; X-Ray Diffraction | 2007 |
Preparation and antitumor characteristics of PLA/(PEG-PPG-PEG) nanoparticles loaded with camptothecin.
Topics: Algorithms; Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Camptothecin; Chromatography, High Pressure Liquid; Excipients; Injections, Intravenous; Lactic Acid; Male; Mice; Nanoparticles; Neoplasm Transplantation; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Rats; Sarcoma 180 | 2007 |
[Preparation and characterization of 7-ethyl-10-hydroxycamptothecin-loaded hypomicron of amphiphilic block copolymer].
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Drug Carriers; Irinotecan; Lactic Acid; Microspheres; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Solubility; Technology, Pharmaceutical | 2007 |
Injectable block copolymer hydrogels for sustained release of a PEGylated drug.
Topics: Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Camptothecin; Delayed-Action Preparations; Drug Delivery Systems; Glycolates; Hydrogels; Injections, Subcutaneous; Kinetics; Lactic Acid; Mice; Mice, Inbred Strains; Microscopy, Electron, Transmission; Phase Transition; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sarcoma 180; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared; Transition Temperature; Viscosity | 2008 |
Particle characteristics and biodistribution of camptothecin-loaded PLA/(PEG-PPG-PEG) nanoparticles.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Hydrogen-Ion Concentration; Lactic Acid; Male; Mice; Nanoparticles; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Propylene Glycols; Sarcoma 180; Solubility; Tissue Distribution | 2008 |
Use of hydrodynamic flow focusing for the generation of biodegradable camptothecin-loaded polymer microspheres.
Topics: Camptothecin; Chromatography, High Pressure Liquid; Lactic Acid; Microspheres; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2008 |
Antibody targeting of camptothecin-loaded PLGA nanoparticles to tumor cells.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Camptothecin; Cell Line, Tumor; Cell Survival; Drug Carriers; fas Receptor; Humans; Immunoconjugates; Intracellular Space; Lactic Acid; Microscopy, Fluorescence; Nanoparticles; Neoplasms; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2008 |
Preparation and in vitro evaluation of actively targetable nanoparticles for SN-38 delivery against HT-29 cell lines.
Topics: Buffers; Camptothecin; Cell Death; Drug Delivery Systems; Folic Acid; HT29 Cells; Humans; Irinotecan; Lactic Acid; Microscopy, Fluorescence; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2010 |
Tumoral acidic pH-responsive MPEG-poly(beta-amino ester) polymeric micelles for cancer targeting therapy.
Topics: Acids; Animals; Camptothecin; Esters; Humans; Lactates; Lactic Acid; Mice; Mice, Nude; Micelles; Neoplasms; Polyethylene Glycols; Polymers | 2010 |
Preparation and pharmacodynamics of stearic acid and poly (lactic-co-glycolic acid) grafted chitosan oligosaccharide micelles for 10-hydroxycamptothecin.
Topics: Antineoplastic Agents, Phytogenic; Biological Transport; Camptothecin; Carbodiimides; Cell Survival; Chemistry, Pharmaceutical; Chitosan; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Stability; Hep G2 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Micelles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Stearic Acids; Technology, Pharmaceutical | 2010 |
Treatment of rat brain tumors using sustained-release of camptothecin from poly(lactic-co-glycolic acid) microspheres in a thermoreversible hydrogel.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Camptothecin; Cell Line, Tumor; Delayed-Action Preparations; Glioma; Hydrogel, Polyethylene Glycol Dimethacrylate; Lactic Acid; Male; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Temperature | 2010 |
Antitumoral activity of camptothecin-loaded nanoparticles in 9L rat glioma model.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Antineoplastic Agents, Phytogenic; beta-Cyclodextrins; Brain Neoplasms; Camptothecin; Cell Line, Tumor; Drug Carriers; Drug Compounding; Female; Glioma; Lactic Acid; Nanoparticles; Neoplasm Transplantation; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Inbred F344; Surface-Active Agents | 2011 |
Preparation and in vitro characterization of 9-nitrocamptothecin-loaded long circulating nanoparticles for delivery in cancer patients.
Topics: Antineoplastic Agents; Calorimetry, Differential Scanning; Camptothecin; Chromatography, High Pressure Liquid; Drug Carriers; Drug Delivery Systems; Drug Stability; Humans; In Vitro Techniques; Lactic Acid; Microscopy, Electron, Scanning; Nanomedicine; Nanoparticles; Neoplasms; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; X-Ray Diffraction | 2010 |
Characterization, blood profile and biodistribution properties of surface modified PLGA nanoparticles of SN-38.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chemistry, Pharmaceutical; Drug Carriers; Folic Acid; Injections, Intravenous; Irinotecan; Lactic Acid; Molecular Structure; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Surface Properties; Tissue Distribution | 2011 |
Development of polymeric and cyclodextrin nanoparticles for camptothecin delivery.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Antineoplastic Agents, Phytogenic; beta-Cyclodextrins; Camptothecin; Cell Line; Drug Delivery Systems; Humans; Lactic Acid; Mice; Nanoparticles; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2010 |
Synthesis, optimization, and characterization of camptothecin-loaded acetalated dextran porous microparticles for pulmonary delivery.
Topics: Acetals; Administration, Inhalation; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Delayed-Action Preparations; Dextrans; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Lactic Acid; Lung; Macrophages, Alveolar; Microspheres; Molecular Weight; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity | 2012 |
Improvement of survival in C6 rat glioma model by a sustained drug release from localized PLGA microspheres in a thermoreversible hydrogel.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brain; Brain Neoplasms; Camptothecin; Cell Line, Tumor; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Fluorescein-5-isothiocyanate; Glioma; Hot Temperature; Hydrogels; Lactic Acid; Male; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Vincristine | 2012 |
Combination therapy of surgical tumor resection with implantation of a hydrogel containing camptothecin-loaded poly(lactic-co-glycolic acid) microspheres in a C6 rat glioma model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin; Cell Line, Tumor; Combined Modality Therapy; Drug Carriers; Drug Implants; Glioma; Hydrogels; Lactic Acid; Male; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley | 2012 |
In vitro targeted imaging and delivery of camptothecin using cetuximab-conjugated multifunctional PLGA-ZnS nanoparticles.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Camptothecin; Cell Line, Tumor; Cetuximab; Drug Carriers; Humans; Lactic Acid; Nanoparticles; Nanotechnology; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sulfides; Zinc Compounds | 2012 |
Preparation, characterization, and cytotoxicity of CPT/Fe₂O₃-embedded PLGA ultrafine composite fibers: a synergistic approach to develop promising anticancer material.
Topics: Animals; Camptothecin; Cell Line; Cell Survival; Drug Carriers; Drug Synergism; Electrochemical Techniques; Lactic Acid; Magnetite Nanoparticles; Mice; Nanofibers; Nanotechnology; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2012 |
Magnetic field activated lipid-polymer hybrid nanoparticles for stimuli-responsive drug release.
Topics: Animals; Camptothecin; Cell Death; Cell Line, Tumor; Cell Proliferation; Lactic Acid; Lipids; Magnetic Fields; Mice; Microscopy, Fluorescence; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Radio Waves; Time Factors | 2013 |
Alpha-tocopheryl polyethylene glycol succinate-emulsified poly(lactic-co-glycolic acid) nanoparticles for reversal of multidrug resistance in vitro.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Emulsions; Humans; Irinotecan; Lactic Acid; Materials Testing; Nanocapsules; Nanoparticles; Neoplasms, Experimental; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E | 2012 |
Definition of formulation design space, in vitro bioactivity and in vivo biodistribution for hydrophilic drug loaded PLGA/PEO-PPO-PEO nanoparticles using OFAT experiments.
Topics: Adsorption; Animals; Caco-2 Cells; Camptothecin; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Humans; Hydrophobic and Hydrophilic Interactions; Irinotecan; Lactic Acid; Male; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Propylene Glycols; Rats; Rats, Wistar; Structure-Activity Relationship; Surface Properties; Time Factors; Tissue Distribution; Tumor Cells, Cultured | 2013 |
Mechanisms of chitosan-coated poly(lactic-co-glycolic acid) nanoparticles for improving oral absorption of 7-ethyl-10-hydroxycamptothecin.
Topics: Absorption; Animals; Caco-2 Cells; Calorimetry, Differential Scanning; Camptothecin; Cell Death; Chitosan; Coated Materials, Biocompatible; Coumarins; Enterocytes; HT29 Cells; Humans; Intestines; Irinotecan; Kinetics; Lactic Acid; Male; Nanoparticles; Particle Size; Perfusion; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Rhodamine 123; Spectroscopy, Fourier Transform Infrared; Static Electricity; X-Ray Diffraction | 2013 |
Engineering polymeric microparticles as theranostic carriers for selective delivery and cancer therapy.
Topics: Antineoplastic Agents; Camptothecin; Cell Line; Cell Line, Tumor; Cell Survival; Drug Carriers; Humans; Lactic Acid; Microspheres; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quantum Dots | 2013 |
Multimodal delivery of irinotecan from microparticles with two distinct compartments.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Delayed-Action Preparations; Dextrans; Hydrogen-Ion Concentration; Irinotecan; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2013 |
SN38 polymeric nanoparticles: in vitro cytotoxicity and in vivo antitumor efficacy in xenograft balb/c model with breast cancer versus irinotecan.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Liberation; Female; Humans; Irinotecan; Lactic Acid; Mammary Neoplasms, Experimental; Mice, Inbred BALB C; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Surface Properties; Tissue Distribution; Xenograft Model Antitumor Assays | 2014 |
Multi-layered nanoparticles for combination gene and drug delivery to tumors.
Topics: Camptothecin; Cell Line, Tumor; Drug Delivery Systems; Gene Transfer Techniques; HCT116 Cells; HEK293 Cells; Humans; Lactic Acid; Nanoparticles; Neoplasms; Plasmids; Polyethyleneimine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; TNF-Related Apoptosis-Inducing Ligand; Transfection | 2014 |
Integrin α(V)β(3)-targeted magnetic nanohybrids with enhanced antitumor efficacy, cell cycle arrest ability, and encouraging anti-cell-migration activity.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Survival; Drug Liberation; HEK293 Cells; Humans; Integrin alphaVbeta3; Lactic Acid; Magnetite Nanoparticles; Maleimides; Micelles; Microscopy, Electron, Transmission; Peptides; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Proton Magnetic Resonance Spectroscopy; Wound Healing | 2014 |
Intravenous delivery of camptothecin-loaded PLGA nanoparticles for the treatment of intracranial glioma.
Topics: Animals; Antineoplastic Agents, Phytogenic; Blood-Brain Barrier; Brain Neoplasms; Camptothecin; Drug Carriers; Feasibility Studies; Glioma; Hydrophobic and Hydrophilic Interactions; Injections, Intravenous; Lactic Acid; Mice; Mice, Inbred C57BL; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Survival Rate; Time Factors | 2015 |
TPGS2k/PLGA nanoparticles for overcoming multidrug resistance by interfering mitochondria of human alveolar adenocarcinoma cells.
Topics: Adenosine Triphosphate; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Camptothecin; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Irinotecan; Lactic Acid; Mitochondria; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E | 2015 |
Preparation, Characterization, and In Vivo Study of 7-Ethyl-14-Aminocamptothecin-Loaded Poly(Ethylene Glycol)2000 -Poly(Lactic Acid)2000 Polymeric Micelles Against H460 Human Nonsmall Cell Lung Carcinoma.
Topics: Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Female; Hep G2 Cells; Humans; Lactic Acid; Lung; Lung Neoplasms; Mice, Nude; Micelles; Polyesters; Polyethylene Glycols; Polymers | 2015 |
Hyaluronic acid-decorated dual responsive nanoparticles of Pluronic F127, PLGA, and chitosan for targeted co-delivery of doxorubicin and irinotecan to eliminate cancer stem-like cells.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Chitosan; Doxorubicin; Drug Delivery Systems; Drug Liberation; Drug Resistance, Neoplasm; Endocytosis; Humans; Hyaluronic Acid; Hydrogen-Ion Concentration; Intracellular Space; Irinotecan; Lactic Acid; Male; Mice, Nude; Nanoparticles; Neoplastic Stem Cells; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spheroids, Cellular; Tissue Distribution | 2015 |
SN-38 active loading in poly(lactic-co-glycolic acid) nanoparticles and assessment of their anticancer properties on COLO-205 human colon adenocarcinoma cells.
Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Drug Screening Assays, Antitumor; Humans; Irinotecan; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2015 |
Hyaluronic acid-functionalized polymeric nanoparticles for colon cancer-targeted combination chemotherapy.
Topics: Animals; Caco-2 Cells; Camptothecin; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Curcumin; Drug Carriers; Drug Synergism; Humans; Hyaluronic Acid; Immunoglobulin G; Lactic Acid; Male; Melphalan; Mice; Mice, Inbred C57BL; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2015 |
Spontaneous arrangement of a tumor targeting hyaluronic acid shell on irinotecan loaded PLGA nanoparticles.
Topics: Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Drug Carriers; Drug Liberation; Humans; Hyaluronan Receptors; Hyaluronic Acid; Irinotecan; Lactic Acid; Molecular Targeted Therapy; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2016 |
Biotin decorated PLGA nanoparticles containing SN-38 designed for cancer therapy.
Topics: Antineoplastic Agents, Phytogenic; Biological Transport; Biotin; Camptothecin; Cell Survival; Drug Carriers; Drug Compounding; Drug Liberation; Female; Humans; Hydrogen-Ion Concentration; Irinotecan; Kinetics; Lactic Acid; MCF-7 Cells; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2017 |
Effects of borneol on the pharmacokinetics of 9-nitrocamptothecin encapsulated in PLGA nanoparticles with different size via oral administration.
Topics: Administration, Oral; Animals; Biological Availability; Camphanes; Camptothecin; Drug Carriers; Drug Delivery Systems; Emulsions; Intestinal Absorption; Lactic Acid; Male; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley | 2016 |
Synergistic retention strategy of RGD active targeting and radiofrequency-enhanced permeability for intensified RF & chemotherapy synergistic tumor treatment.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Proliferation; Cell Survival; Combined Modality Therapy; Drug Delivery Systems; Drug Liberation; Fluorescent Dyes; HeLa Cells; Humans; Lactic Acid; Menthol; Mice, Nude; Neoplasm Transplantation; Oligopeptides; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pulsed Radiofrequency Treatment; Rats; Surface Properties | 2016 |
Advanced interstitial chemotherapy combined with targeted treatment of malignant glioma in rats by using drug-loaded nanofibrous membranes.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bibenzyls; Brain; Brain Neoplasms; Camptothecin; Cisplatin; Disease Models, Animal; Drug Delivery Systems; Ethylnitrosourea; Glioblastoma; Glioma; Humans; Irinotecan; Lactic Acid; Male; Nanofibers; Neurosurgical Procedures; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Tumor Burden | 2016 |
Achieving High Drug Loading and Sustained Release of Hydrophobic Drugs in Hydrogels through In Situ Crystallization.
Topics: Camptothecin; Crystallization; Delayed-Action Preparations; Drug Delivery Systems; Humans; Hydrogels; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Neoplasms; Polyethylene Glycols | 2017 |
PLGA-PEG-RA-based polymeric micelles for tumor targeted delivery of irinotecan.
Topics: Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Hep G2 Cells; HT29 Cells; Humans; Irinotecan; Lactic Acid; Liver Neoplasms; Micelles; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglactin 910; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tretinoin | 2018 |
Irinotecan and 5-fluorouracil-co-loaded, hyaluronic acid-modified layer-by-layer nanoparticles for targeted gastric carcinoma therapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Delivery Systems; Fluorouracil; Humans; Hyaluronic Acid; Irinotecan; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Stomach Neoplasms | 2017 |
Improvement of oral efficacy of Irinotecan through biodegradable polymeric nanoparticles through in vitro and in vivo investigations.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Brain; Caco-2 Cells; Camptothecin; Chitosan; Drug Carriers; Humans; Intestinal Absorption; Irinotecan; Lactic Acid; Male; MCF-7 Cells; Nanoparticles; Neoplasms; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar | 2018 |
[Preparation and quality evaluation of comet-shaped hydroxy camptothecin-loaded amphiphilic block copolymer].
Topics: Calorimetry, Differential Scanning; Camptothecin; Cell Line; Drug Carriers; Humans; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; X-Ray Diffraction | 2016 |