camptothecin has been researched along with hoe 33342 in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.85) | 18.7374 |
| 1990's | 5 (19.23) | 18.2507 |
| 2000's | 12 (46.15) | 29.6817 |
| 2010's | 7 (26.92) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, M; Tandon, V | 1 |
| Ajitha, A; Akunuri, R; Kamal, A; Kovvuri, J; Nagaraju, B; Nagesh, N; Nayak, VL; Rao, MPN | 1 |
| Bruno, S; Darzynkiewicz, Z; Del Bino, G; Yi, PN | 1 |
| Debenham, PG; Smith, PJ; Watson, JV | 1 |
| Bodley, A; Chen, AY; Liu, LF; Peng, LF; Yu, C | 1 |
| Gatto, B; Kim, JS; LaVoie, EJ; Liu, A; Liu, LF; Sun, Q; Yu, C | 1 |
| Chen, AY; Mitchell, JB; Okunieff, P; Pommier, Y | 1 |
| Goldman, GH; La Voie, EJ; Liu, LF; Sanders, MM; Wu, HY; Yu, C | 1 |
| Barbier, M; Boutonnat, J; Grunwald, D; Mousseau, M; Muirhead, K; Ronot, X; Seigneurin, D | 1 |
| Bedner, E; Darzynkiewicz, Z; Halicka, HD | 1 |
| Akao, Y; Banno, Y; Hattori, M; Hirabayasi, Y; Kito, M; Kusakabe, S; Nakagawa, Y; Nozawa, Y; Ohishi, N; Sawada, M; Tamiya-Koizumi, K | 1 |
| Poot, M; Rabinovitch, PS; Silber, JR | 1 |
| Chan, PJ; Jacobson, JD; King, A; Patton, WC; Rowland, SC | 1 |
| Baran, V; Czikková, S; Fabian, D; Il'ková, G; Koppel, J; Rehák, P | 2 |
| Danks, MK; Morton, CL; Potter, PM; Sampath, J; Schuetz, JD; Wall, A; Wierdl, M | 1 |
| Dwarakanath, BS; Khaitan, D; Ravindranath, T | 1 |
| Saravia, NG; Walker, J | 1 |
| Li, GZ; Li, KS; Li, ZH; Yang, WM; Yu, WH; Zhou, XM | 1 |
| Coombs, GH; Goyeneche, D; Jean-Moreno, V; Rojas, R; Walker, J | 1 |
| Choi, JY; Han, JY; Kim, JY; Park, IH | 1 |
| Asanuma, H; Hasegawa, T; Hirata, K; Hirohashi, Y; Inoda, S; Ishitani, K; Kondo, T; Morita, R; Nakatsugawa, M; Nishizawa, S; Sato, N; Takahashi, A; Tamura, Y; Terui, T; Torigoe, T; Tsuruma, T | 1 |
| Ahn, JS; Asami, Y; Erikson, RL; Jang, JH; Kim, BY; Kim, SO; Kim, YS; Kwon, YT; Lee, KS; N R, T; Sakchaisri, K; Soung, NK; Thimmegowda, NR | 1 |
| Juvale, K; Lamprecht, A; Singh, MS; Wiese, M | 1 |
| Bansal, S; Sur, S; Tandon, V | 1 |
| Cao, M; Fan, M; Hu, Z; Huang, W; Jin, X; Wang, F; Wu, H; Zhang, Y | 1 |
26 other study(ies) available for camptothecin and hoe 33342
| Article | Year |
|---|---|
Synthesis and biological activity of novel inhibitors of topoisomerase I: 2-aryl-substituted 2-bis-1H-benzimidazoles.
Topics: Animals; Antineoplastic Agents; Benzimidazoles; Cattle; Cell Proliferation; DNA; DNA Cleavage; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HeLa Cells; Humans; Molecular Structure; Stereoisomerism; Structure-Activity Relationship; Topoisomerase I Inhibitors | 2011 |
Design, synthesis and biological evaluation of new β-carboline-bisindole compounds as DNA binding, photocleavage agents and topoisomerase I inhibitors.
Topics: Antineoplastic Agents; Binding Sites; Carbolines; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Indoles; Molecular Docking Simulation; Molecular Structure; Photosensitizing Agents; Structure-Activity Relationship; Topoisomerase I Inhibitors | 2018 |
Apoptotic cell death triggered by camptothecin or teniposide. The cell cycle specificity and effects of ionizing radiation.
Topics: Apoptosis; Benzimidazoles; Camptothecin; Doxorubicin; G2 Phase; Gamma Rays; Humans; Mitosis; Teniposide; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Vinblastine | 1992 |
A role of DNA topoisomerases in the active dissociation of DNA minor groove-ligand complexes. A flow cytometric study of inhibitor effects.
Topics: Animals; Benzimidazoles; Camptothecin; Cell Line; Cell Nucleus; DNA; DNA Topoisomerases, Type I; Flow Cytometry; In Vitro Techniques; Ligands; Mice; Novobiocin; Thymidine Kinase; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; X-Rays | 1989 |
A new mammalian DNA topoisomerase I poison Hoechst 33342: cytotoxicity and drug resistance in human cell cultures.
Topics: Benzimidazoles; Camptothecin; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Drug Resistance; Fluorescent Dyes; Humans; KB Cells; Lymphocytes; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1993 |
Structure-activity relationships of benzimidazoles and related heterocycles as topoisomerase I poisons.
Topics: Antineoplastic Agents, Phytogenic; Benzimidazoles; Benzoxazoles; Camptothecin; Cell Line; DNA Damage; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Humans; Structure-Activity Relationship; Topoisomerase I Inhibitors | 1996 |
Mammalian DNA topoisomerase I mediates the enhancement of radiation cytotoxicity by camptothecin derivatives.
Topics: Animals; Antineoplastic Agents, Phytogenic; Benzimidazoles; Camptothecin; Cell Cycle; Cells, Cultured; Cricetinae; Cricetulus; DNA; DNA Topoisomerases, Type I; Humans; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured | 1997 |
Differential poisoning of human and Aspergillus nidulans DNA topoisomerase I by bi- and terbenzimidazoles.
Topics: Antifungal Agents; Aspergillus nidulans; Benzimidazoles; Binding Sites; Camptothecin; DNA Topoisomerases, Type I; Drug Resistance, Microbial; Fluorescent Dyes; Humans; Saccharomyces cerevisiae; Substrate Specificity; Topoisomerase I Inhibitors | 1997 |
Response of chemosensitive and chemoresistant leukemic cell lines to drug therapy: simultaneous assessment of proliferation, apoptosis, and necrosis.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Camptothecin; Cell Division; Doxorubicin; Drug Resistance, Neoplasm; Flow Cytometry; Fluorescent Dyes; Humans; Irinotecan; Leukemia, Myeloid; Necrosis; Propidium; Tranexamic Acid; Tumor Cells, Cultured; Vincristine | 2000 |
Segregation of RNA and separate packaging of DNA and RNA in apoptotic bodies during apoptosis.
Topics: Apoptosis; Benzimidazoles; Bromouracil; Camptothecin; Coloring Agents; Cycloheximide; Dactinomycin; DNA; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Fluorescent Dyes; HL-60 Cells; Humans; Pyronine; RNA; Topoisomerase I Inhibitors; Tumor Necrosis Factor-alpha; Uridine | 2000 |
Ceramide accumulation is independent of camptothecin-induced apoptosis in prostate cancer LNCaP cells.
Topics: Antineoplastic Agents; Apoptosis; Benzimidazoles; Camptothecin; Carboxylic Acids; Caspases; Ceramides; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Fumonisins; Humans; Male; Oxidoreductases; Prostatic Neoplasms; Sphingomyelin Phosphodiesterase; Sphingomyelins; Tumor Cells, Cultured | 2002 |
A novel flow cytometric technique for drug cytotoxicity gives results comparable to colony-forming assays.
Topics: 4-Nitroquinoline-1-oxide; Antimetabolites; Antineoplastic Agents, Phytogenic; Benzimidazoles; Bromodeoxyuridine; Camptothecin; Carcinogens; Cell Division; Cell Line; Cell Survival; Fibroblasts; Flow Cytometry; Fluorescent Dyes; Humans; Lymphocytes; Stem Cells; Werner Syndrome | 2002 |
Dual fluorescence analysis of DNA apoptosis in sperm.
Topics: Apoptosis; Benzimidazoles; Camptothecin; Cell Survival; Coloring Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Dyes; Genistein; Humans; Male; Microscopy, Fluorescence; Necrosis; Propidium; Spermatozoa; Staining and Labeling | 2003 |
Induced cell death of preimplantation mouse embryos cultured in vitro evaluated by comet assay.
Topics: Animals; Apoptosis; Benzimidazoles; Blastocyst; Camptothecin; Comet Assay; Culture Techniques; Dactinomycin; DNA; Embryo, Mammalian; Embryonic Development; Female; Fluorescent Dyes; Mice; Mice, Inbred ICR; Pregnancy; Propidium | 2003 |
Carboxylesterase-mediated sensitization of human tumor cells to CPT-11 cannot override ABCG2-mediated drug resistance.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzimidazoles; Biological Transport; Camptothecin; Carboxylic Ester Hydrolases; Cell Division; Drug Resistance, Neoplasm; Humans; Irinotecan; Neoplasm Proteins; Rabbits; Tumor Cells, Cultured | 2003 |
Inhibitory effect of IGF-I on induced apoptosis in mouse preimplantation embryos cultured in vitro.
Topics: Animals; Apoptosis; Benzimidazoles; Blastocyst; Camptothecin; Cell Nucleus; Comet Assay; Culture Techniques; Dactinomycin; DNA Damage; Embryonic Development; Female; Fluorescent Dyes; Humans; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred ICR; Pregnancy; Recombinant Proteins | 2004 |
2-deoxy-D-glucose enhances the cytotoxicity of topoisomerase inhibitors in human tumor cell lines.
Topics: Adenosine Triphosphate; Antimetabolites; Antineoplastic Agents, Phytogenic; Benzimidazoles; Brain Neoplasms; Camptothecin; Carcinoma, Squamous Cell; Cell Survival; Deoxyglucose; DNA Damage; Drug Interactions; Enzyme Inhibitors; Etoposide; Glioma; Humans; Radiation-Sensitizing Agents; Topoisomerase Inhibitors; Tumor Cells, Cultured | 2004 |
Inhibition of Leishmania donovani promastigote DNA topoisomerase I and human monocyte DNA topoisomerases I and II by antimonial drugs and classical antitopoisomerase agents.
Topics: Animals; Antimony; Antimony Potassium Tartrate; Antimony Sodium Gluconate; Antiprotozoal Agents; Benzimidazoles; Bisbenzimidazole; Camptothecin; Cell Survival; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Leishmania donovani; Meglumine; Meglumine Antimoniate; Monocytes; Organometallic Compounds; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; U937 Cells | 2004 |
[Comparison between two methods for staining DNA of apoptotic spermatozoa].
Topics: Apoptosis; Benzimidazoles; Camptothecin; Cell Survival; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluorescent Dyes; Genistein; Humans; Male; Propidium; Sensitivity and Specificity; Spermatozoa; Staining and Labeling | 2005 |
Leishmania donovani: differential activities of classical topoisomerase inhibitors and antileishmanials against parasite and host cells at the level of DNA topoisomerase I and in cytotoxicity assays.
Topics: Acid Phosphatase; Animals; Antimony Sodium Gluconate; Antiprotozoal Agents; Benzimidazoles; Berberine Alkaloids; Bisbenzimidazole; Camptothecin; Cell Line; Diminazene; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Leishmania donovani; Luciferases, Firefly; Luminescent Agents; Macrophages; Monocytes; Pentamidine; Quercetin; Topoisomerase I Inhibitors | 2006 |
Simvastatin enhances irinotecan-induced apoptosis in human non-small cell lung cancer cells by inhibition of proteasome activity.
Topics: Apoptosis; Benzimidazoles; Blotting, Western; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Drug Screening Assays, Antitumor; Drug Synergism; Flow Cytometry; Humans; I-kappa B Proteins; Irinotecan; Lung Neoplasms; NF-kappa B; NF-KappaB Inhibitor alpha; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Simvastatin; Staining and Labeling; Substrate Specificity | 2011 |
Cytotoxic T lymphocytes efficiently recognize human colon cancer stem-like cells.
Topics: Animals; Antigens; Antineoplastic Agents; Benzimidazoles; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Etoposide; Humans; Irinotecan; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Neoplastic Stem Cells; Peptides; T-Lymphocytes, Cytotoxic | 2011 |
STK295900, a dual inhibitor of topoisomerase 1 and 2, induces G(2) arrest in the absence of DNA damage.
Topics: Aniline Compounds; Antineoplastic Agents, Phytogenic; Benzimidazoles; Camptothecin; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA, Neoplasm; Dose-Response Relationship, Drug; Etoposide; G2 Phase Cell Cycle Checkpoints; HCT116 Cells; HeLa Cells; Hep G2 Cells; HT29 Cells; Humans; Immunoblotting; MCF-7 Cells; Molecular Structure; Neoplasms; Phosphorylation; Topoisomerase Inhibitors | 2013 |
Evaluation of dual P-gp-BCRP inhibitors as nanoparticle formulation.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzimidazoles; Camptothecin; Chemistry, Pharmaceutical; Chlorophyll; Dogs; Doxorubicin; Irinotecan; Madin Darby Canine Kidney Cells; Microscopy, Confocal; Nanoparticles; Neoplasm Proteins; Rhodamine 123 | 2015 |
Benzimidazoles: Selective Inhibitors of Topoisomerase I with Differential Modes of Action.
Topics: Benzimidazoles; Camptothecin; Catalytic Domain; DNA; DNA Topoisomerases, Type I; Escherichia coli; Escherichia coli Proteins; Humans; Molecular Docking Simulation; Mutation; Piperazines; Plasmids; Protein Binding; Topoisomerase I Inhibitors | 2019 |
AMPK-mTOR-ULK1 axis activation-dependent autophagy promotes hydroxycamptothecin-induced apoptosis in human bladder cancer cells.
Topics: Adenylate Kinase; Apoptosis; Autophagy; Autophagy-Related Protein-1 Homolog; Benzimidazoles; Camptothecin; Cell Line, Tumor; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Intracellular Signaling Peptides and Proteins; Molecular Structure; TOR Serine-Threonine Kinases; Urinary Bladder Neoplasms | 2020 |