camptothecin has been researched along with glycine in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (22.73) | 18.2507 |
| 2000's | 8 (36.36) | 29.6817 |
| 2010's | 8 (36.36) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Beitrand, R; Jenkins, J; Kohlhagen, G; Pommier, Y; Tabuchi, A; Tanizawa, A | 1 |
| Conover, CD; Gilbert, CW; Greenwald, RB; Pendri, A; Shum, KL | 1 |
| Andoh, T; Sugimoto, Y; Tsuruo, T; Yanase, K | 1 |
| Mangold, G; Manikumar, G; Marty, J; Potter, PM; Vladu, B; Von Hoff, DD; Wadkins, RM; Wall, ME; Wani, MC; Weitman, S | 1 |
| Amatruda, JF; Benedetti, P; Bjornsti, MA; Butler, RH; Fiorani, P; Silvestri, A | 1 |
| Choi, CH; Chung, MH; Jeong, JH; Kim, HS; Kim, MS; Kweon, OS; Lee, TB; Lim, DY; Min, YD; Rha, HS; You, HJ | 1 |
| Bhatt, R; Buhler, KR; de Vries, P; Heasley, E; Klein, P; Singer, JW; Tulinsky, J | 1 |
| de, J; Kapchina, VM; Woltering, EJ; Yakimova, ET | 1 |
| Ando, M; Hanioka, N; Ishida, S; Jinno, H; Nishimura, T; Ozawa, S; Saeki, M; Saito, Y; Sawada, J; Tanaka-Kagawa, T | 1 |
| Burke, TG; Liu, X; Lynn, BC; Song, L; Zhang, J | 1 |
| Bennett, SA; Cheung, EC; Cregan, SP; Ferguson, KL; McIntosh, WC; Melanson-Drapeau, L; Park, DS; Slack, RS; Vanderluit, JL | 1 |
| Arakawa, Y; Saito, S; Suzuki, H; Yamada, H | 1 |
| Bjornsti, MA; van der Merwe, M | 1 |
| Chao, P; Deshmukh, M; Gao, D; Kutscher, HL; Sinko, PJ | 1 |
| Efferth, T; Konkimalla, VB | 1 |
| Bruns, H; Büchler, MW; Hoffmann, K; Longerich, T; Mikalauskas, S; Mikalauskiene, L; Nickkholgh, A; Schemmer, P; Strupas, K | 1 |
| Holland, JF; Ohnuma, T; Oussenko, IA; Reddy, EP | 1 |
| Cho, JK; Chun, C; Kuh, HJ; Song, SC | 1 |
| Bracke, B; Chapelle, T; Driessen, A; Francque, S; Hartman, V; Huyghe, I; Morrison, S; Op de Beeck, B; Roeyen, G; Ysebaert, D | 1 |
| D'Annessa, I; Dasari, JB; Fiorani, P; Messina, B; Ottaviani, A; Soren, BC; Tesauro, C; Thareparambil, A; Wang, Z | 1 |
| Li, Q; Shen, Q; Wang, Y; Weng, Q; Zhang, X; Zhou, L | 1 |
22 other study(ies) available for camptothecin and glycine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Cloning of Chinese hamster DNA topoisomerase I cDNA and identification of a single point mutation responsible for camptothecin resistance.
Topics: Amino Acid Sequence; Animals; Arabidopsis; Base Sequence; Camptothecin; Cell Line; Cloning, Molecular; Conserved Sequence; Cricetinae; Cricetulus; DNA Primers; DNA Topoisomerases, Type I; DNA, Complementary; Drosophila melanogaster; Drug Resistance; Glycine; Humans; Lung; Mice; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Serine; Viruses | 1993 |
Camptothecin delivery systems: enhanced efficacy and tumor accumulation of camptothecin following its conjugation to polyethylene glycol via a glycine linker.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Colorectal Neoplasms; Drug Carriers; Glycine; Humans; Injections, Intraperitoneal; Injections, Intravenous; Mice; Mice, Nude; Neoplasm Transplantation; Polyethylene Glycols; Prodrugs; Tissue Distribution; Tritium | 1998 |
Retroviral expression of a mutant (Gly-533) human DNA topoisomerase I cDNA confers a dominant form of camptothecin resistance.
Topics: Anti-Bacterial Agents; Antineoplastic Agents, Phytogenic; Blotting, Western; Camptothecin; DNA Topoisomerases, Type I; DNA, Complementary; Drug Resistance, Microbial; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Glycine; HeLa Cells; Humans; Mutation; Neomycin; Nucleic Acid Conformation; Polymerase Chain Reaction; Retroviridae; Transduction, Genetic; Transfection; Uterine Cervical Neoplasms | 1999 |
Water soluble 20(S)-glycinate esters of 10,11-methylenedioxycamptothecins are highly active against human breast cancer xenografts.
Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cholinesterase Inhibitors; Drug Screening Assays, Antitumor; Esters; Female; Glycine; Humans; Infant, Newborn; Irinotecan; Mice; Mice, Nude; Molecular Structure; Neoplasm Transplantation; Solubility; Structure-Activity Relationship; Tumor Cells, Cultured | 1999 |
Domain interactions affecting human DNA topoisomerase I catalysis and camptothecin sensitivity.
Topics: Alanine; Amino Acid Substitution; Camptothecin; Catalysis; DNA; DNA Topoisomerases, Type I; Drug Resistance; Enzyme Inhibitors; Enzyme Stability; Glycine; Humans; Models, Molecular; Mutation; Protein Conformation; Protein Structure, Tertiary; Saccharomyces cerevisiae; Threonine; Topoisomerase I Inhibitors; Transfection | 1999 |
Reactive oxygen species-specific mechanisms of drug resistance in paraquat-resistant acute myelogenous leukemia sublines.
Topics: Alkynes; Antineoplastic Agents; Camptothecin; Cell Survival; Cisplatin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Glutathione Transferase; Glycine; Humans; Leukemia, Myeloid, Acute; Metallothionein; Paraquat; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Superoxide Dismutase; Tumor Cells, Cultured; Vincristine | 2000 |
Water-soluble poly-(L-glutamic acid)-Gly-camptothecin conjugates enhance camptothecin stability and efficacy in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Glycine; HT29 Cells; Humans; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Molecular Weight; Neoplasm Transplantation; Polyglutamic Acid; Solubility | 2001 |
A critical role for ethylene in hydrogen peroxide release during programmed cell death in tomato suspension cells.
Topics: Apoptosis; Aspartic Acid; Calcium; Calcium Channels; Camptothecin; Caspase Inhibitors; Cells, Cultured; Ethylenes; Glycine; Hydrogen Peroxide; Lanthanum; Mitogen-Activated Protein Kinases; Oxidation-Reduction; Plant Growth Regulators; Solanum lycopersicum; Tosyllysine Chloromethyl Ketone | 2002 |
Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38), an active metabolite of irinotecan (CPT-11), by human UGT1A1 variants, G71R, P229Q, and Y486D.
Topics: Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Camptothecin; Chlorocebus aethiops; COS Cells; Genetic Variation; Glucuronides; Glucuronosyltransferase; Glutamine; Glycine; Humans; Irinotecan; Proline; Tyrosine | 2003 |
Degradation of camptothecin-20(S)-glycinate ester prodrug under physiological conditions.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Chromatography, Liquid; Drug Stability; Glycine; Hydrogen-Ion Concentration; Hydrolysis; Molecular Structure; Prodrugs; Spectrometry, Mass, Electrospray Ionization; Time Factors | 2004 |
Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Apoptosis Inducing Factor; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Benzodiazepines; Benzothiadiazines; Camptothecin; Caspase Inhibitors; Cells, Cultured; Cerebellum; Cerebral Cortex; Convulsants; Dizocilpine Maleate; Drug Resistance; Flavoproteins; Glutamic Acid; Glycine; Hippocampus; Kainic Acid; Male; Membrane Proteins; Mice; Mice, Knockout; Mice, Mutant Strains; N-Methylaspartate; Neurons; Neurotoxins; Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Fusion Proteins; Seizures | 2005 |
Novel missense mutation of the DNA topoisomerase I gene in SN-38-resistant DLD-1 cells.
Topics: Amino Acid Substitution; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Glycine; Humans; Irinotecan; Mutation, Missense; Protein Conformation; Serine | 2006 |
Mutation of Gly721 alters DNA topoisomerase I active site architecture and sensitivity to camptothecin.
Topics: Base Sequence; Binding Sites; Camptothecin; Catalysis; Catalytic Domain; Crystallography, X-Ray; DNA Topoisomerases, Type I; Enzyme Inhibitors; Glycine; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Mutation; Protein Structure, Tertiary; Saccharomyces cerevisiae | 2008 |
A series of alpha-amino acid ester prodrugs of camptothecin: in vitro hydrolysis and A549 human lung carcinoma cell cytotoxicity.
Topics: Alanine; Aminobutyrates; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Proliferation; Cell Survival; Esters; Glycine; Humans; Hydrolysis; Lung Neoplasms; Prodrugs; Tumor Cells, Cultured; Valine | 2010 |
Inhibition of epidermal growth factor receptor-overexpressing cancer cells by camptothecin, 20-(N,N-diethyl) glycinate.
Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Drug Evaluation, Preclinical; ErbB Receptors; Glycine; Humans; Neoplasms | 2010 |
Dietary glycine protects from chemotherapy-induced hepatotoxicity.
Topics: Animals; Antineoplastic Agents; Camptothecin; Chemical and Drug Induced Liver Injury; Colorectal Neoplasms; Dietary Supplements; Drug-Related Side Effects and Adverse Reactions; Fatty Liver; Female; Fluorouracil; Glycine; Immunohistochemistry; Irinotecan; Kupffer Cells; Leucovorin; Liver; Microcirculation; Neoadjuvant Therapy; Nitric Oxide Synthase Type II; Organoplatinum Compounds; Oxaliplatin; Phagocytosis; Rats; Rats, Sprague-Dawley; Transaminases | 2011 |
Effect of ON 01910.Na, an anticancer mitotic inhibitor, on cell-cycle progression correlates with RanGAP1 hyperphosphorylation.
Topics: Camptothecin; Cell Cycle; Cell Line, Tumor; DNA Damage; Doxorubicin; Glycine; GTPase-Activating Proteins; Humans; Mitosis; Phosphorylation; Polymerization; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Signal Transduction; Sulfones; SUMO-1 Protein; Tubulin | 2011 |
Injectable poly(organophosphazene)-camptothecin conjugate hydrogels: synthesis, characterization, and antitumor activities.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Drug Stability; Drug Storage; Female; Glycine; Humans; Hydrogels; Injections; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Organophosphorus Compounds; Phase Transition; Polymers; Temperature; Xenograft Model Antitumor Assays | 2012 |
Estimation of the future remnant liver function is a better tool to predict post-hepatectomy liver failure than platelet-based liver scores.
Topics: Aniline Compounds; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Glycine; Hepatectomy; Humans; Imino Acids; Irinotecan; Liver Failure; Liver Function Tests; Liver Neoplasms; Male; Middle Aged; Organoplatinum Compounds; Organotechnetium Compounds; Oxaliplatin; Platelet Function Tests; Predictive Value of Tests; Radiopharmaceuticals; Treatment Outcome | 2017 |
The human DNA topoisomerase I mutant Gly717Asp: Higher religation rate is not always associated with camptothecin resistance.
Topics: Antineoplastic Agents, Phytogenic; Aspartic Acid; Binding Sites; Camptothecin; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Glycine; Humans; Kinetics; Mutation; Proteolysis | 2019 |
In Vitro Metabolism of E2, G2: Novel Bile Acid-Coupling Camptothecin Analogues, in Rat Liver Microsomes.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bile Acids and Salts; Camptothecin; Chromatography, Liquid; Deoxycholic Acid; Glycine; Mass Spectrometry; Microsomes, Liver; Rats | 2021 |