Page last updated: 2024-08-22

camptothecin and glutamine

camptothecin has been researched along with glutamine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's10 (83.33)29.6817
2010's1 (8.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Al-Zoubi, A; Boucher, J; Savarese, D1
Baumgartner, G; Cosentini, E; Haberl, I; Hamilton, G; Mallinger, R; Pertschy, P; Teleky, B; Wenzl, E1
Ando, M; Hanioka, N; Ishida, S; Jinno, H; Nishimura, T; Ozawa, S; Saeki, M; Saito, Y; Sawada, J; Tanaka-Kagawa, T1
Baer, KA; Chang, EB; Musch, MW; Riehm, J; Ropeleski, MJ1
Ansari, R; Cheng, L; Helft, P; Juliar, B; Loehrer, P; Pan, CX; Pletcher, W; Seitz, D; Sweeney, C; Vinson, J1
Ikegami, Y; Ishikawa, T; Matsuda, Y; Onishi, Y; Sawada, S; Takeda, M; Tamura, A; Tsuji, M; Wakabayashi, K1
Baracos, VE; Dieleman, LA; Field, CJ; Sawyer, MB; Xue, H1
Baracos, VE; Dieleman, LA; Field, CJ; Murray, D; Sawyer, MB; Xue, H1
Baracos, VE; Dieleman, LA; Field, CJ; Le Roy, S; Sawyer, MB; Xue, H1
Chen, B; Fu, W; Gaiddon, C; Gross, I; Han, X; Hou, L; Hou, Y; Li, L; Liang, Y; Long, B; Meng, X; Pang, W; Wang, L; Wang, Y; Xu, C; Yao, H; Zhang, X; Zhong, T; Zhou, K1

Trials

1 trial(s) available for camptothecin and glutamine

ArticleYear
A phase II trial of irinotecan, 5-fluorouracil and leucovorin combined with celecoxib and glutamine as first-line therapy for advanced colorectal cancer.
    Oncology, 2005, Volume: 69, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Celecoxib; Colorectal Neoplasms; Cyclooxygenase Inhibitors; Diarrhea; Disease-Free Survival; Drug Administration Schedule; Female; Fluorouracil; Glutamine; Humans; Irinotecan; Leucovorin; Male; Middle Aged; Pyrazoles; Sulfonamides; Treatment Outcome

2005

Other Studies

11 other study(ies) available for camptothecin and glutamine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Glutamine for irinotecan diarrhea.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000, Volume: 18, Issue:2

    Topics: Aged; Antineoplastic Agents, Phytogenic; Camptothecin; Colonic Neoplasms; Diarrhea; Female; Glutamine; Humans; Irinotecan; Male; Middle Aged; Rectal Neoplasms

2000
The differentiation inducers phenylacetate and phenylbutyrate modulate camptothecin sensitivity in colon carcinoma cells in vitro by intracellular acidification.
    International journal of oncology, 2001, Volume: 19, Issue:5

    Topics: Annexin A5; Antineoplastic Agents, Phytogenic; Apoptosis; Bicarbonates; Camptothecin; Cell Cycle; Cell Differentiation; Cell Survival; Colonic Neoplasms; Drug Resistance, Neoplasm; Glutamine; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Phenylacetates; Phenylbutyrates; Tumor Cells, Cultured

2001
Glucuronidation of 7-ethyl-10-hydroxycamptothecin (SN-38), an active metabolite of irinotecan (CPT-11), by human UGT1A1 variants, G71R, P229Q, and Y486D.
    Drug metabolism and disposition: the biological fate of chemicals, 2003, Volume: 31, Issue:1

    Topics: Amino Acid Substitution; Animals; Arginine; Aspartic Acid; Camptothecin; Chlorocebus aethiops; COS Cells; Genetic Variation; Glucuronides; Glucuronosyltransferase; Glutamine; Glycine; Humans; Irinotecan; Proline; Tyrosine

2003
Anti-apoptotic effects of L-glutamine-mediated transcriptional modulation of the heat shock protein 72 during heat shock.
    Gastroenterology, 2005, Volume: 129, Issue:1

    Topics: Apoptosis; Camptothecin; Cell Line; Cell Nucleus; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression; Genes, Reporter; Glutamine; Heat Shock Transcription Factors; Heat-Shock Proteins; Heat-Shock Response; HSP72 Heat-Shock Proteins; Humans; Intestinal Mucosa; Luciferases; Phosphorylation; Promoter Regions, Genetic; Topoisomerase II Inhibitors; Transcription Factors; Transcription, Genetic

2005
Re-evaluation and functional classification of non-synonymous single nucleotide polymorphisms of the human ATP-binding cassette transporter ABCG2.
    Cancer science, 2007, Volume: 98, Issue:2

    Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Camptothecin; Cell Line; Chromosomes, Human; DNA, Complementary; Drug Resistance; Gene Expression; Genome, Human; Glutamine; Humans; In Situ Hybridization, Fluorescence; Molecular Structure; Mutation; Neoplasm Proteins; Polymorphism, Single Nucleotide; Valine

2007
Nutritional modulation of antitumor efficacy and diarrhea toxicity related to irinotecan chemotherapy in rats bearing the ward colon tumor.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Dec-01, Volume: 13, Issue:23

    Topics: Animals; Camptothecin; Colonic Neoplasms; Diarrhea; Diet; Fatty Acids, Omega-3; Female; Food-Drug Interactions; Glutamine; Irinotecan; Oligosaccharides; Probiotics; Rats

2007
Bolus oral glutamine protects rats against CPT-11-induced diarrhea and differentially activates cytoprotective mechanisms in host intestine but not tumor.
    The Journal of nutrition, 2008, Volume: 138, Issue:4

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Camptothecin; Colon; Colonic Neoplasms; Cytoprotection; Diarrhea; Female; Glutamine; Irinotecan; Neoplasms, Experimental; Rats

2008
Single and combined supplementation of glutamine and n-3 polyunsaturated fatty acids on host tolerance and tumour response to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin (CPT-11)/5-fluorouracil chemotherapy in rats bearing Ward colo
    The British journal of nutrition, 2009, Volume: 102, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Body Weight; Camptothecin; Colonic Neoplasms; Combined Modality Therapy; Diarrhea; Dietary Supplements; Fatty Acids, Omega-3; Female; Fluorouracil; Glutamine; Immune Tolerance; Irinotecan; Leukocyte Count; Nutritional Status; Rats; Rats, Inbred F344; Treatment Failure; Xenograft Model Antitumor Assays

2009
Anti-tumor effects of P-LPK-CPT, a peptide-camptothecin conjugate, in colorectal cancer.
    Communications biology, 2022, 11-14, Volume: 5, Issue:1

    Topics: Amino Acid Transport System ASC; Camptothecin; Colorectal Neoplasms; Glutamine; Humans; Minor Histocompatibility Antigens; Molecular Docking Simulation; Peptides

2022