Page last updated: 2024-08-22

camptothecin and folic acid

camptothecin has been researched along with folic acid in 50 studies

Research

Studies (50)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	11 (22.00)	29.6817
2010's	34 (68.00)	24.3611
2020's	5 (10.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Adler, G; Lutz, MP	1
Höffken, K; Kliche, KO; Kubsch, K; Masri-Zada, R; Raida, M	1
Curley, SA; Ellis, LM; Gentner, B; Parikh, AA; Vauthey, JN; Wu, TT	1
Baba, E; Fujishima, H; Harada, M; Kikuchi, I; Mitsugi, K; Miyanaga, O; Nakano, S; Ueda, A	1
Chen, Y; Kholodovych, V; Paranjpe, PV; Sinko, PJ; Stein, S; Welsh, W	1
Paranjpe, PV; Sinko, PJ; Stein, S	1
Assenat, E; Duffour, J; Ychou, M	1
Doorneweerd, DD; Henne, WA; Hilgenbrink, AR; Kularatne, SA; Low, PS	1
Caca, K; Feisthammel, J; Mössner, J; Schoppmeyer, K; Schulze, M; Wiedmann, M	1
Feng, L; Gu, B; Han, X; Liu, J; Liu, M; Liu, Y; Lu, W; Xie, C; Zhan, C	1
Choi, MK; Chung, SJ; Jin, QR; Kim, DD; Shim, CK; Shim, WS; Song, IS; Tian, GY; Yang, SG	1
Atyabi, F; Azizi, E; Dinarvand, R; Ebrahimnejad, P; Jaafari, MR; Nomani, AR; Rad-Malekshahi, M; Sajadi, A	1
Liu, L; Xia, J; Zhang, L; Zhang, Z; Zhao, Q	1
Atyabi, F; Dinarvand, R; Ebrahimnejad, P; Jafari, MR; Tabasi, SA	1
Gao, Y; Li, Q; Liu, C; Su, L; Sun, B; Wang, Y; Zhang, B; Zhao, D; Zhao, Q; Zhao, X; Zu, Y	1
Beninati, S; Desideri, A; Galbiati, A; Mattioli, P; Morozzo Della Rocca, B; Paradossi, G; Tabolacci, C	1
Li, Z; Lu, J; Tamanoi, F; Zink, JI	1
Jiang, R; Li, Y; Sun, Z; Wang, D; Zhang, Q; Zhao, D; Zhao, X; Zu, B; Zu, Y	2
Cheng, T; Guan, XM; Lan, JF; Liu, XY; Shen, JM; Zhang, HX	1
Yao, J; Zhang, Z	1
An, F; Diao, X; Hao, X; Li, W; Liu, Z; Wang, C; Yang, Y; Zhang, X	1
Backendorf, C; Chatzopoulou, A; den Dulk, H; Kros, A; Lamers, GE; Morrhayim, J; Porta, F; Schaaf, M; Zink, JI	1
Cao, J; Cui, S; Gu, Y; Qian, Z; Zhu, H	1
Li, Z; Liu, Z; Pu, F; Qu, X; Ren, J; Yang, X	1
Carron, JD; Hakenjos, J; Henne, KL; Henne, WA; Kularatne, SA	1
Besznyák, I; Bursics, A; Dede, K; Fekete, A; Kőszegi, G; Láng, I; Mersich, T; Mester, G; Pörneczi, B	1
Bloomfield, A; Dorton, R; Guan, J; Leamon, CP; Nelson, M; Reddy, JA; Vetzel, M	1
Chen, M; Chen, Z; Li, X; Liu, C; Luo, X; Yuan, J; Zhao, Y	1
Chen, RC; Chen, WT; Kang, ST; Lin, JL; Wang, CH; Yeh, CK	1
Chen, HP; Chen, MH; Liu, TY; Tung, FI	1
Chen, Y; Feng, Y; Fu, S; Qin, X; Sun, X; Wu, J; Yang, B; You, H; Yu, Y; Zhang, G	1
Li, Q; Liang, H; Sun, B; Wang, W; Xu, J; Zeng, Z; Zhao, X	1
Choi, HG; Choi, Y; Jeong, JH; Kim, JO; Thapa, RK; Yong, CS; Youn, YS	1
Duan, X; Fan, L; Li, W; Qiao, Y; Wu, H; Yang, T; Zhu, L	1
Chen, M; Chen, Z; Li, X; Luo, X; Xie, S; Zhang, Y	1
Gao, YE; Hou, M; Kang, Y; Liu, S; Shi, X; Xu, Z; Xue, P	1
Enoch, IVMV; Ramasamy, S; Sam David, RJR	1
Chen, Y; Fan, Z; Hou, Z; Li, Y; Lin, J; Ma, J; Su, G; Xie, L; Zhang, H; Zhang, Y; Zhu, X	1
Bai, S; Gao, YE; Hou, M; Kang, Y; Li, B; Ma, X; Shi, X; Xiao, B; Xu, Z; Xue, P	1
Dahiru, NS; Dramou, P; Fizir, M; He, H; Itatahine, A; Mehdi, YA; Taleb, A; Wei, L; Zhang, J	1
Chakraborty, A; Chakraborty, P; Das, S; Nandi, AK; Pal, S; Panja, A	1
Ao, M; Cao, Y; Hao, L; Hu, Z; Huang, J; Li, A; Li, P; Liu, J; Liu, Y; Ran, H; Wang, Z; Xu, F; Xu, J; Yao, Y	1
Decker, T; Denzlinger, C; Fischer von Weikersthal, L; Freiberg-Richter, J; Giessen-Jung, C; Graeven, U; Heinemann, V; Held, S; Jung, A; Kirchner, T; Modest, DP; Peuser, B; Peveling Genannt Reddemann, C; Schenk, M; Schuch, G; Schwaner, I; Stahler, A; Stintzing, S; Uhlig, J; Vehling-Kaiser, U	1
Alinejad, A; Hashemzadeh, H; Raissi, H	1
Alexander, A; Arivarasu, A; Enoch, IVMV; Kaliyamoorthy, K; Pillai, AS; Ramasamy, S	1
Havaldar, DV; Moholkar, DN; Pawar, KD; Sadalage, PS	1
Fu, T; Li, Y; Liu, Y; Long, W; Stang, PJ; Tan, W; Yan, Y; Zhang, P; Zhao, Z; Zhou, Z	1
Chen, Y; Cheng, J; Jiao, Q; Shao, Y; Wang, X; Xiang, L; Zheng, X; Zhou, S	1

Reviews

2 review(s) available for camptothecin and folic acid

Article	Year
[Chemotherapy of colorectal carcinoma]. Der Internist, 2001, Volume: 42, Issue:12 Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma; Chemotherapy, Adjuvant; Clinical Trials as Topic; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Folic Acid; Humans; Irinotecan; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Survival Analysis; Treatment Outcome	2001
[Irinotecan for the treatment of metastatic colorectal cancer]. Bulletin du cancer, 2006, Volume: 93, Issue:5 Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Folic Acid; Humans; Irinotecan; Maximum Tolerated Dose; Multicenter Studies as Topic; Pharmacogenetics	2006

Article

Year

[Chemotherapy of colorectal carcinoma].

Der Internist, 2001, Volume: 42, Issue:12

Topics: Administration, Oral; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma; Chemotherapy, Adjuvant; Clinical Trials as Topic; Colorectal Neoplasms; Drug Administration Schedule; Fluorouracil; Folic Acid; Humans; Irinotecan; Neoadjuvant Therapy; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Survival Analysis; Treatment Outcome

2001

[Irinotecan for the treatment of metastatic colorectal cancer].

Bulletin du cancer, 2006, Volume: 93, Issue:5

Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Capecitabine; Clinical Trials as Topic; Colorectal Neoplasms; Deoxycytidine; Fluorouracil; Folic Acid; Humans; Irinotecan; Maximum Tolerated Dose; Multicenter Studies as Topic; Pharmacogenetics

2006

Trials

4 trial(s) available for camptothecin and folic acid

Article	Year
Chronomodulated chemotherapy in metastatic gastrointestinal cancer combining 5-FU and sodium folinate with oxaliplatin, irinotecan or gemcitabine: the Jena experience in 79 patients. Journal of cancer research and clinical oncology, 2002, Volume: 128, Issue:9 Topics: Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Camptothecin; Colorectal Neoplasms; Deoxycytidine; Female; Fluorouracil; Folic Acid; Gastrointestinal Neoplasms; Gemcitabine; Humans; Irinotecan; Male; Middle Aged; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Stomach Neoplasms	2002
Phase I study of CPT-11 and bolus 5-FU/ l-leucovorin in patients with metastatic colorectal cancer. International journal of clinical oncology, 2004, Volume: 9, Issue:2 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Fluorouracil; Folic Acid; Humans; Infusions, Intravenous; Irinotecan; Leucovorin; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Treatment Outcome	2004
Irinotecan with 5-FU/FA in advanced biliary tract adenocarcinomas: a multicenter phase II trial. American journal of clinical oncology, 2007, Volume: 30, Issue:3 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Biliary Tract Neoplasms; Camptothecin; Female; Fluorouracil; Folic Acid; Humans; Irinotecan; Male; Middle Aged; Survival Analysis; Vitamin B Complex	2007
Sequential Versus Combination Therapy of Metastatic Colorectal Cancer Using Fluoropyrimidines, Irinotecan, and Bevacizumab: A Randomized, Controlled Study-XELAVIRI (AIO KRK0110). Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019, 01-01, Volume: 37, Issue:1 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Deoxycytidine; Drug Administration Schedule; Female; Fluorouracil; Folic Acid; Humans; Irinotecan; Leucovorin; Male	2019

Other Studies

44 other study(ies) available for camptothecin and folic acid

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Perioperative complications in patients undergoing major liver resection with or without neoadjuvant chemotherapy. Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2003, Volume: 7, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Camptothecin; Colonic Neoplasms; Female; Fluorouracil; Folic Acid; Hepatectomy; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Postoperative Complications; Retrospective Studies	2003
Tumor-targeted bioconjugate based delivery of camptothecin: design, synthesis and in vitro evaluation. Journal of controlled release : official journal of the Controlled Release Society, 2004, Nov-24, Volume: 100, Issue:2 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Carboxylic Acids; Carrier Proteins; Cell Survival; Chemistry, Pharmaceutical; CHO Cells; Cricetinae; Drug Delivery Systems; Drug Design; Drug Stability; Electrophoresis, Polyacrylamide Gel; Fluorescent Dyes; Folate Receptors, GPI-Anchored; Folic Acid; Humans; KB Cells; Lactones; Magnetic Resonance Spectroscopy; Models, Molecular; Receptors, Cell Surface; Spectroscopy, Fourier Transform Infrared	2004
Tumor-targeted and activated bioconjugates for improved camptothecin delivery. Anti-cancer drugs, 2005, Volume: 16, Issue:7 Topics: Amino Acids; Animals; Antineoplastic Agents; Camptothecin; Cathepsin B; Cell Line, Tumor; Drug Delivery Systems; Drug Stability; Esters; Female; Folic Acid; Humans; Hydrolysis; Models, Molecular; Molecular Conformation; Neoplasm Transplantation; Polyethylene Glycols; Rats; Rats, Inbred F344; Xenograft Model Antitumor Assays	2005
Synthesis and activity of a folate peptide camptothecin prodrug. Bioorganic & medicinal chemistry letters, 2006, Oct-15, Volume: 16, Issue:20 Topics: Binding, Competitive; Camptothecin; Carrier Proteins; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Folate Receptors, GPI-Anchored; Folic Acid; Humans; In Vitro Techniques; Molecular Structure; Prodrugs; Receptors, Cell Surface; Stereoisomerism; Time Factors	2006
9-NC-loaded folate-conjugated polymer micelles as tumor targeted drug delivery system: preparation and evaluation in vitro. International journal of pharmaceutics, 2009, May-08, Volume: 372, Issue:1-2 Topics: Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Drug Delivery Systems; Drug Evaluation, Preclinical; Folic Acid; HeLa Cells; Humans; Micelles; Neoplasms; Polymers	2009
Decreased urinary secretion of belotecan in folic acid-induced acute renal failure rats due to down-regulation of Oat1 and Bcrp. Xenobiotica; the fate of foreign compounds in biological systems, 2009, Volume: 39, Issue:10 Topics: Acridines; Acute Kidney Injury; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Camptothecin; Down-Regulation; Folic Acid; Glomerular Filtration Rate; Indicators and Reagents; Kidney; Male; Organic Anion Transport Protein 1; p-Aminohippuric Acid; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines; Verapamil; Vitamin B Complex	2009
Preparation and in vitro evaluation of actively targetable nanoparticles for SN-38 delivery against HT-29 cell lines. Nanomedicine : nanotechnology, biology, and medicine, 2010, Volume: 6, Issue:3 Topics: Buffers; Camptothecin; Cell Death; Drug Delivery Systems; Folic Acid; HT29 Cells; Humans; Irinotecan; Lactic Acid; Microscopy, Fluorescence; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer	2010
Functional graphene oxide as a nanocarrier for controlled loading and targeted delivery of mixed anticancer drugs. Small (Weinheim an der Bergstrasse, Germany), 2010, Feb-22, Volume: 6, Issue:4 Topics: Antineoplastic Agents; Camptothecin; Carbon; Cell Line, Tumor; Cell Survival; Doxorubicin; Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Microscopy, Atomic Force; Rhodamines; Solutions; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared	2010
Characterization, blood profile and biodistribution properties of surface modified PLGA nanoparticles of SN-38. International journal of pharmaceutics, 2011, Mar-15, Volume: 406, Issue:1-2 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chemistry, Pharmaceutical; Drug Carriers; Folic Acid; Injections, Intravenous; Irinotecan; Lactic Acid; Molecular Structure; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Surface Properties; Tissue Distribution	2011
Preparation, characterization and targeting of micronized 10-hydroxycamptothecin-loaded folate-conjugated human serum albumin nanoparticles to cancer cells. International journal of nanomedicine, 2011, Volume: 6 Topics: Antineoplastic Agents, Phytogenic; Calorimetry, Differential Scanning; Camptothecin; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Carriers; Drug Delivery Systems; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Folic Acid; Humans; Microscopy, Confocal; Microscopy, Electron, Scanning; Nanomedicine; Nanoparticles; Particle Size; Serum Albumin; X-Ray Diffraction	2011
Targeting tumor cells through chitosan-folate modified microcapsules loaded with camptothecin. Bioconjugate chemistry, 2011, Jun-15, Volume: 22, Issue:6 Topics: Adsorption; Animals; Antineoplastic Agents; Camptothecin; Capsules; Cell Proliferation; Chitosan; Drug Carriers; Drug Delivery Systems; Drug Screening Assays, Antitumor; Folic Acid; HeLa Cells; Humans; Mice; Molecular Structure; NIH 3T3 Cells; Structure-Activity Relationship; Surface Properties; Tumor Cells, Cultured	2011
In vivo tumor suppression efficacy of mesoporous silica nanoparticles-based drug-delivery system: enhanced efficacy by folate modification. Nanomedicine : nanotechnology, biology, and medicine, 2012, Volume: 8, Issue:2 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Drug Delivery Systems; Folic Acid; Humans; Mice; Mice, Inbred BALB C; Nanoparticles; Pancreatic Neoplasms; Silicates; Transplantation, Heterologous	2012
A novel preparation method for camptothecin (CPT) loaded folic acid conjugated dextran tumor-targeted nanoparticles. International journal of molecular sciences, 2011, Volume: 12, Issue:7 Topics: Antineoplastic Agents, Phytogenic; Calorimetry, Differential Scanning; Camptothecin; Carbon Dioxide; Chemistry, Pharmaceutical; Dextrans; Dimethyl Sulfoxide; Drug Carriers; Folic Acid; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Spectroscopy, Fourier Transform Infrared; Surface Properties; X-Ray Diffraction	2011
Preparation and characterization of camptothecin (CPT)-loaded folate-conjugated dextran nanoparticles for tumor-targeted drug delivery using supercritical antisolvent method. Journal of controlled release : official journal of the Controlled Release Society, 2011, Nov-30, Volume: 152 Suppl 1 Topics: Antineoplastic Agents, Phytogenic; Calorimetry, Differential Scanning; Camptothecin; Chemistry, Pharmaceutical; Chromatography, Supercritical Fluid; Dextrans; Drug Carriers; Drug Compounding; Folic Acid; Kinetics; Microscopy, Electron, Scanning; Nanoparticles; Nanotechnology; Particle Size; Solubility; Solvents; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; X-Ray Diffraction	2011
Luminescent/magnetic hybrid nanoparticles with folate-conjugated peptide composites for tumor-targeted drug delivery. Bioconjugate chemistry, 2012, May-16, Volume: 23, Issue:5 Topics: Antineoplastic Agents, Phytogenic; Cadmium Compounds; Camptothecin; Cell Line, Tumor; Chitosan; Drug Delivery Systems; Folic Acid; Humans; Luminescence; Luminescent Agents; Magnetite Nanoparticles; Micelles; Neoplasms; Oligopeptides; Quantum Dots; Tellurium	2012
Preparation of irinotecan-loaded folate-targeted liposome for tumor targeting delivery and its antitumor activity. AAPS PharmSciTech, 2012, Volume: 13, Issue:3 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Drug Delivery Systems; Folic Acid; Irinotecan; Liposomes; Mice; Mice, Inbred ICR; Random Allocation; Rats; Xenograft Model Antitumor Assays	2012
Carrier-free, functionalized drug nanoparticles for targeted drug delivery. Chemical communications (Cambridge, England), 2012, Aug-21, Volume: 48, Issue:65 Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Maleic Anhydrides; Nanoparticles; Neoplasms; Polyethylene Glycols	2012
Folic acid-modified mesoporous silica nanoparticles for cellular and nuclear targeted drug delivery. Advanced healthcare materials, 2013, Volume: 2, Issue:2 Topics: Antineoplastic Agents; Blotting, Western; Camptothecin; Cell Line, Tumor; Drug Carriers; Folic Acid; Humans; In Situ Nick-End Labeling; Microscopy, Confocal; Nanoparticles; Silicon Dioxide	2013
Enhanced tumor targeting and antitumor efficacy via hydroxycamptothecin-encapsulated folate-modified N-succinyl-N'-octyl chitosan micelles. Journal of pharmaceutical sciences, 2013, Volume: 102, Issue:4 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Mice; Mice, Nude; Micelles; Neoplasms; Rats	2013
Near-infrared-controlled, targeted hydrophobic drug-delivery system for synergistic cancer therapy. Chemistry (Weinheim an der Bergstrasse, Germany), 2013, Jul-29, Volume: 19, Issue:31 Topics: Animals; Antineoplastic Agents; Camptothecin; Drug Delivery Systems; Folic Acid; Gold; HeLa Cells; Humans; Hydrophobic and Hydrophilic Interactions; Infrared Rays; Mice; Nanotubes; Polyethylene Glycols; Spectroscopy, Near-Infrared; Temperature	2013
Synthesis and activity of a folate targeted monodisperse PEG camptothecin conjugate. Bioorganic & medicinal chemistry letters, 2013, Nov-01, Volume: 23, Issue:21 Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Drug Delivery Systems; Folate Receptors, GPI-Anchored; Folic Acid; Humans; KB Cells; Neoplasms; Polyethylene Glycols; Prodrugs	2013
[Preoperative chemotherapy in the surgical treatment of colorectal liver metastases]. Magyar sebeszet, 2013, Volume: 66, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Female; Fluorouracil; Folic Acid; Hepatectomy; Hospitals, General; Humans; Irinotecan; Kaplan-Meier Estimate; Length of Stay; Liver Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Operative Time; Organoplatinum Compounds; Oxaliplatin; Surgery Department, Hospital; Treatment Outcome	2013
Rational combination therapy of vintafolide (EC145) with commonly used chemotherapeutic drugs. Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Apr-15, Volume: 20, Issue:8 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carboplatin; Cell Line, Tumor; Cell Proliferation; Cisplatin; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Folic Acid; HeLa Cells; Humans; Irinotecan; Mice, Inbred BALB C; Mice, Inbred DBA; Mice, Nude; Neoplasms; Neoplasms, Experimental; Paclitaxel; Taxoids; Topotecan; Treatment Outcome; Vinca Alkaloids; Xenograft Model Antitumor Assays	2014
Folate-decorated and reduction-sensitive micelles assembled from amphiphilic polymer-camptothecin conjugates for intracellular drug delivery. Molecular pharmaceutics, 2014, Nov-03, Volume: 11, Issue:11 Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Survival; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Female; Folic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Lactones; Micelles; Molecular Structure; Ovarian Neoplasms; Polyethylene Glycols; Surface Properties; Tissue Distribution; Tumor Cells, Cultured	2014
Targeted tumor theranostics using folate-conjugated and camptothecin-loaded acoustic nanodroplets in a mouse xenograft model. Biomaterials, 2015, Volume: 53 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Folic Acid; Humans; Male; Mice; Mice, Inbred NOD; Mice, SCID; Nanostructures; Neoplasms; Theranostic Nanomedicine; Xenograft Model Antitumor Assays	2015
A novel micelle-forming material used for preparing a theranostic vehicle exhibiting enhanced in vivo therapeutic efficacy. Journal of medicinal chemistry, 2015, May-14, Volume: 58, Issue:9 Topics: Animals; Antineoplastic Agents; Camptothecin; Carbocyanines; Cell Line, Tumor; Chitosan; Delayed-Action Preparations; Drug Carriers; Female; Ferric Compounds; Fluorescence; Fluorescent Dyes; Folic Acid; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Magnetic Fields; Magnets; Mice, Nude; Micelles; Nanoparticles; Sonication	2015
A study of the synergistic effect of folate-decorated polymeric micelles incorporating Hydroxycamptothecin with radiotherapy on xenografted human cervical carcinoma. Colloids and surfaces. B, Biointerfaces, 2016, Apr-01, Volume: 140 Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Chemoradiotherapy; Drug Delivery Systems; Female; Fluorodeoxyglucose F18; Folic Acid; G2 Phase Cell Cycle Checkpoints; HeLa Cells; Histones; Humans; Mice, Inbred BALB C; Mice, Nude; Micelles; Microscopy, Electron, Transmission; Phosphorylation; Polyesters; Polyethylene Glycols; Polymers; Positron-Emission Tomography; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays	2016
Pharmacokinetics and Tissue Distribution of Folate-Decorated Human Serum Albumin Loaded With Nano-Hydroxycamptothecin for Tumor Targeting. Journal of pharmaceutical sciences, 2016, Volume: 105, Issue:6 Topics: Animals; Breast Neoplasms; Camptothecin; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Female; Folic Acid; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Serum Albumin, Human; Tissue Distribution; Xenograft Model Antitumor Assays	2016
Folate-Mediated Targeted Delivery of Combination Chemotherapeutics Loaded Reduced Graphene Oxide for Synergistic Chemo-Photothermal Therapy of Cancers. Pharmaceutical research, 2016, Volume: 33, Issue:11 Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Cell Survival; Docetaxel; Drug Carriers; Drug Liberation; Drug Synergism; Female; Folic Acid; Graphite; Hep G2 Cells; Humans; Irinotecan; MCF-7 Cells; Nanoparticles; Particle Size; Phototherapy; Surface Properties; Taxoids	2016
Preparation of Two Types of Polymeric Micelles Based on Poly(β-L-Malic Acid) for Antitumor Drug Delivery. PloS one, 2016, Volume: 11, Issue:9 Topics: Antineoplastic Agents; Camptothecin; Cell Survival; Drug Compounding; Drug Delivery Systems; Drug Liberation; Folic Acid; HeLa Cells; Humans; Malates; Micelles; Microscopy, Confocal; Microscopy, Electron, Transmission; Polyethylene Glycols; Polymers	2016
Synergistic antitumor efficacy of redox and pH dually responsive micelleplexes for co-delivery of camptothecin and genes. Acta biomaterialia, 2017, Volume: 49 Topics: Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Cell Line, Tumor; Drug Delivery Systems; Electrophoresis, Agar Gel; Endocytosis; Female; Fluorescence; Folic Acid; Gene Transfer Techniques; Hydrogen-Ion Concentration; Mice, Inbred BALB C; Micelles; Neoplasm Metastasis; Oxidation-Reduction; Particle Size; Polyethylene Glycols; Proteins; Transfection; Tumor Burden; Tumor Necrosis Factor-alpha	2017
Rapidly cell-penetrating and reductive milieu-responsive nanoaggregates assembled from an amphiphilic folate-camptothecin prodrug for enhanced drug delivery and controlled release. Biomaterials science, 2017, Feb-28, Volume: 5, Issue:3 Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Delayed-Action Preparations; Drug Delivery Systems; Folic Acid; Glutathione; Humans; Neoplasms; Prodrugs	2017
Folate-molecular encapsulator-tethered biocompatible polymer grafted with magnetic nanoparticles for augmented drug delivery. Artificial cells, nanomedicine, and biotechnology, 2018, Volume: 46, Issue:sup2 Topics: beta-Cyclodextrins; Biocompatible Materials; Camptothecin; Capsules; Dextrans; Drug Carriers; Drug Liberation; Ferric Compounds; Folic Acid; HeLa Cells; Humans; Magnetite Nanoparticles; Models, Molecular; Molecular Conformation; Nickel; Zinc Compounds	2018
Integration of phospholipid-hyaluronic acid-methotrexate nanocarrier assembly and amphiphilic drug-drug conjugate for synergistic targeted delivery and combinational tumor therapy. Biomaterials science, 2018, Jun-25, Volume: 6, Issue:7 Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Camptothecin; Drug Carriers; Drug Compounding; Drug Synergism; Female; Folate Receptors, GPI-Anchored; Folic Acid; Humans; Hyaluronic Acid; MCF-7 Cells; Methotrexate; Mice; Mice, Nude; Nanoparticles; Phosphatidylethanolamines; Survival Analysis; Tumor Burden; Xenograft Model Antitumor Assays	2018
Methotrexate-based amphiphilic prodrug nanoaggregates for co-administration of multiple therapeutics and synergistic cancer therapy. Acta biomaterialia, 2018, 09-01, Volume: 77 Topics: A549 Cells; Animals; Antineoplastic Agents; Biological Availability; Camptothecin; Disulfides; Doxorubicin; Drug Delivery Systems; Drug Evaluation, Preclinical; Drug Liberation; Drug Synergism; Female; Folic Acid; Folic Acid Transporters; HeLa Cells; Humans; Hydrazones; Lysosomes; MCF-7 Cells; Methotrexate; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Nanostructures; Neoplasm Transplantation; Neoplasms; Prodrugs	2018
Folic acid-conjugated chitosan oligosaccharide-magnetic halloysite nanotubes as a delivery system for camptothecin. Carbohydrate polymers, 2018, Oct-01, Volume: 197 Topics: Antineoplastic Agents; Camptothecin; Cell Proliferation; Cell Survival; Chitosan; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Screening Assays, Antitumor; Folic Acid; Humans; Nanotubes; Oligosaccharides; Structure-Activity Relationship; Tumor Cells, Cultured	2018
Injectable Hydrogel of Vitamin B ChemMedChem, 2018, 11-20, Volume: 13, Issue:22 Topics: Animals; Antineoplastic Agents; Camptothecin; CHO Cells; Cricetulus; Diffusion; Doxorubicin; Drug Carriers; Drug Liberation; Folic Acid; Gluconates; HeLa Cells; Humans; Hydrogels; Hydrogen-Ion Concentration; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Lactones; Mice	2018
Low-intensity focused ultrasound (LIFU)-activated nanodroplets as a theranostic agent for noninvasive cancer molecular imaging and drug delivery. Biomaterials science, 2018, Nov-01, Volume: 6, Issue:11 Topics: Animals; Camptothecin; Cell Line, Tumor; Cell Transformation, Neoplastic; Drug Delivery Systems; Fluorocarbons; Folic Acid; Humans; Magnetite Nanoparticles; Mice; Mice, Nude; Molecular Imaging; Nanostructures; Theranostic Nanomedicine; Tissue Distribution; Ultrasonic Waves	2018
Understanding co-loading of doxorubicin and camptothecin on graphene and folic acid-conjugated graphene for targeting drug delivery: classical MD simulation and DFT calculation. Journal of biomolecular structure & dynamics, 2020, Volume: 38, Issue:9 Topics: Camptothecin; Density Functional Theory; Doxorubicin; Drug Carriers; Drug Delivery Systems; Folic Acid; Graphite; Molecular Dynamics Simulation	2020
β-Cyclodextrin-folate functionalized poly(lactic-co-glycolide)-superparamagnetic ytterbium ferrite hybrid nanocarrier for targeted delivery of camptothecin. Materials science & engineering. C, Materials for biological applications, 2021, Volume: 122 Topics: beta-Cyclodextrins; Camptothecin; Drug Carriers; Ferric Compounds; Folic Acid; Humans; Magnetic Iron Oxide Nanoparticles; Nanoparticles; Ytterbium	2021
Engineering the liposomal formulations from natural peanut phospholipids for pH and temperature sensitive release of folic acid, levodopa and camptothecin. Materials science & engineering. C, Materials for biological applications, 2021, Volume: 123 Topics: Arachis; Camptothecin; Folic Acid; Humans; Hydrogen-Ion Concentration; Levodopa; Liposomes; Phospholipids; Temperature	2021
Self-assembled Pt(II) metallacycles enable precise cancer combination chemotherapy. Proceedings of the National Academy of Sciences of the United States of America, 2022, 05-17, Volume: 119, Issue:20 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Liberation; Drug Synergism; Folic Acid; Humans; Mice; Nanoparticles; Neoplasms; Platinum; Polymers; Stilbenes; Tumor Microenvironment	2022
Folate Decoration Supports the Targeting of Camptothecin Micelles against Activated Hepatic Stellate Cells and the Suppression of Fibrogenesis. ACS applied materials & interfaces, 2023, Jan-11, Volume: 15, Issue:1 Topics: Animals; Camptothecin; Drug Carriers; Drug Delivery Systems; Folic Acid; Hepatic Stellate Cells; Mice; Micelles; Polyethylene Glycols	2023