Compounds > camptothecin

Page last updated: 2024-08-22

camptothecin and ecteinascidin 743

camptothecin has been researched along with ecteinascidin 743 in 14 studies

Research

Studies (14)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (7.14)	18.2507
2000's	5 (35.71)	29.6817
2010's	8 (57.14)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Corey, EJ; Martinez, EJ; Owa, T; Schreiber, SL	1
Carrassa, L; D'Incalci, M; Damia, G; Faircloth, GT; Filiberti, L; Foiani, M; Liberi, G; Silvestri, S	1
Patel, SR	1
Banerjee, D; Bertino, JR; Brennan, MF; Chou, TC; Guan, Y; Li, W; Scotto, KW; Takahashi, N; Wada-Takahashi, Y	1
D'Incalci, M; Faircloth, GT; Jimeno, J; Marabese, M; Mazzarella, G; Meco, D; Riccardi, A; Riccardi, R; Ubezio, P	1
Dean-Colomb, W; Esteva, FJ	1
Grohar, PJ; Helman, LJ	1
D'Incalci, M; Grohar, PJ; Helman, LJ; Mendoza, A; Pommier, Y; Segars, LE; Yeung, C	1
Burdach, S	1
Hamasaki, T; Hisamatsu, T; Kawano, M; Kimura, T; Kishimoto, T; Mabuchi, S; Matsumoto, Y; Sasano, T; Sawada, K; Takahashi, K; Takahashi, R; Takahashi, T	1
Burdach, S; D'Incalci, M; DaPrada, GA; Fregoni, V; Grohar, PJ; Pavesi, L; Riccardi, A; Tancredi, R; Zambelli, A	1
Allonca, E; Astudillo, A; Fernandez-Garcia, MT; Garcia-Pedrero, JM; Martinez-Cruzado, L; Rodriguez, A; Rodriguez, R; Santos, L; Tornin, J	1
Bouvet, M; Clary, B; Han, Q; Hoffman, RM; Singh, SR; Sun, YU; Tan, Y; Ye, J; Zhao, M; Zhu, G	1

Reviews

3 review(s) available for camptothecin and ecteinascidin 743

Article	Year
Developing therapeutic pharmaceuticals for the treatment of soft-tissue sarcomas. Expert opinion on investigational drugs, 2002, Volume: 11, Issue:12 Topics: Antineoplastic Agents; Benzamides; Camptothecin; Dacarbazine; Deoxycytidine; Dioxoles; Gemcitabine; Humans; Imatinib Mesylate; Irinotecan; Isoquinolines; Piperazines; Pyrimidines; Sarcoma; Temozolomide; Tetrahydroisoquinolines; Trabectedin	2002
Emerging agents in the treatment of anthracycline- and taxane-refractory metastatic breast cancer. Seminars in oncology, 2008, Volume: 35, Issue:2 Suppl 2 Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Clinical Trials as Topic; Deoxycytidine; Dioxoles; Diphtheria Toxin; Drug Resistance, Neoplasm; Drugs, Investigational; Epothilones; Female; Furans; Gemcitabine; Glutamates; Guanine; Humans; Interleukin-2; Ketones; Lapatinib; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Pemetrexed; Quinazolines; Recombinant Fusion Proteins; Tetrahydroisoquinolines; Trabectedin; Vinblastine; Vinorelbine	2008
Prospects and challenges for the development of new therapies for Ewing sarcoma. Pharmacology & therapeutics, 2013, Volume: 137, Issue:2 Topics: Antineoplastic Agents; Bone Neoplasms; Camptothecin; Clinical Trials as Topic; Dioxoles; Epigenesis, Genetic; Humans; Molecular Targeted Therapy; Poly(ADP-ribose) Polymerase Inhibitors; Sarcoma, Ewing; Somatomedins; Tetrahydroisoquinolines; Trabectedin	2013

Other Studies

11 other study(ies) available for camptothecin and ecteinascidin 743

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Phthalascidin, a synthetic antitumor agent with potency and mode of action comparable to ecteinascidin 743. Proceedings of the National Academy of Sciences of the United States of America, 1999, Mar-30, Volume: 96, Issue:7 Topics: Antineoplastic Agents, Alkylating; Bleomycin; Camptothecin; Cell Division; Cisplatin; Cross-Linking Reagents; Dioxoles; DNA Topoisomerases, Type I; DNA, Neoplasm; Doxorubicin; Etoposide; Female; Humans; Isoquinolines; Male; Mitomycin; Models, Molecular; Molecular Structure; Neoplasm Proteins; Paclitaxel; Phthalimides; Structure-Activity Relationship; Tetrahydroisoquinolines; Trabectedin; Tumor Cells, Cultured	1999
Unique pattern of ET-743 activity in different cellular systems with defined deficiencies in DNA-repair pathways. International journal of cancer, 2001, May-15, Volume: 92, Issue:4 Topics: Androstadienes; Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Camptothecin; Cell Survival; CHO Cells; Cricetinae; Dioxoles; DNA; DNA Repair; DNA Topoisomerases, Type I; DNA-Activated Protein Kinase; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Isoquinolines; Nuclear Proteins; Protein Serine-Threonine Kinases; Tetrahydroisoquinolines; Trabectedin; Tumor Cells, Cultured; Wortmannin	2001
Sequence-dependent synergistic cytotoxicity of ecteinascidin-743 and paclitaxel in human breast cancer cell lines in vitro and in vivo. Cancer research, 2002, Dec-01, Volume: 62, Issue:23 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Camptothecin; Cisplatin; Dioxoles; Doxorubicin; Drug Administration Schedule; Drug Synergism; Female; Fluorouracil; Humans; Inhibitory Concentration 50; Isoquinolines; Mice; Mice, Nude; Mitosis; Paclitaxel; Tetrahydroisoquinolines; Trabectedin; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2002
Combination of trabectedin and irinotecan is highly effective in a human rhabdomyosarcoma xenograft. Anti-cancer drugs, 2005, Volume: 16, Issue:8 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Dioxoles; DNA Topoisomerases, Type I; Humans; In Vitro Techniques; Irinotecan; Isoquinolines; Male; Mice; Mice, Nude; Rhabdomyosarcoma; Tetrahydroisoquinolines; Trabectedin; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2005
Dual targeting of EWS-FLI1 activity and the associated DNA damage response with trabectedin and SN38 synergistically inhibits Ewing sarcoma cell growth. Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Mar-01, Volume: 20, Issue:5 Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Dioxoles; Disease Models, Animal; DNA Breaks, Double-Stranded; DNA Damage; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Exodeoxyribonucleases; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Irinotecan; Mice; Oncogene Proteins, Fusion; Phenotype; Proto-Oncogene Protein c-fli-1; RecQ Helicases; RNA Interference; RNA-Binding Protein EWS; RNA, Small Interfering; Sarcoma, Ewing; Tetrahydroisoquinolines; Trabectedin; Werner Syndrome Helicase; Xenograft Model Antitumor Assays	2014
Molecular precision chemotherapy: overcoming resistance to targeted therapies? Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Mar-01, Volume: 20, Issue:5 Topics: Animals; Antineoplastic Agents; Camptothecin; Dioxoles; DNA Damage; Female; Humans; Irinotecan; Oncogene Proteins, Fusion; Proto-Oncogene Protein c-fli-1; RNA-Binding Protein EWS; Sarcoma, Ewing; Tetrahydroisoquinolines; Trabectedin	2014
Combination treatment with trabectedin and irinotecan or topotecan has synergistic effects against ovarian clear cell carcinoma cells. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2014, Volume: 24, Issue:5 Topics: Adenocarcinoma, Clear Cell; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Camptothecin; Cell Proliferation; Cisplatin; Dioxoles; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Everolimus; Female; Humans; Irinotecan; Ovarian Neoplasms; Paclitaxel; Sirolimus; Tetrahydroisoquinolines; Topotecan; Trabectedin; Tumor Cells, Cultured	2014
Targeting the EWS-FLI1 transcription factor in Ewing sarcoma. Cancer chemotherapy and pharmacology, 2015, Volume: 75, Issue:6 Topics: Adult; Camptothecin; Dioxoles; Humans; Irinotecan; Male; Oncogene Proteins, Fusion; Proto-Oncogene Protein c-fli-1; RNA-Binding Protein EWS; Sarcoma, Ewing; Tetrahydroisoquinolines; Trabectedin	2015
Trabectedin and Campthotecin Synergistically Eliminate Cancer Stem Cells in Cell-of-Origin Sarcoma Models. Neoplasia (New York, N.Y.), 2017, Volume: 19, Issue:6 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Cell Cycle Checkpoints; Cell Proliferation; Dioxoles; DNA Damage; Drug Synergism; Humans; Liposarcoma; Liposarcoma, Myxoid; Mice; Neoplastic Stem Cells; Signal Transduction; Tetrahydroisoquinolines; Trabectedin; Xenograft Model Antitumor Assays	2017
Combination of Trabectedin With Irinotecan, Leucovorin and 5-Fluorouracil Arrests Primary Colorectal Cancer in an Imageable Patient-derived Orthotopic Xenograft Mouse Model. Anticancer research, 2019, Volume: 39, Issue:12 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Camptothecin; Colorectal Neoplasms; Fluorouracil; Green Fluorescent Proteins; Humans; Leucovorin; Mice; Mice, Nude; Mice, Transgenic; Random Allocation; Trabectedin; Tumor Burden; Xenograft Model Antitumor Assays	2019