Page last updated: 2024-08-22

camptothecin and decitabine

camptothecin has been researched along with decitabine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's4 (33.33)29.6817
2010's7 (58.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Abbruzzese, JL; Anzai, H; Frost, P1
Bernard, O; Gagnon, JF; Guillemette, C; Têtu, B; Villeneuve, L1
Enomoto, M; Iida, S; Ishiguro, M; Kato, K; Makino, H; Morita, S; Sugihara, K; Takagi, Y; Uetake, H1
Cortés, F; Mateos, S; Orta, ML1
Ding, L; Guo, B; Qiu, L; Zhang, J1
Bai, T; Kobayashi, A; Matsuoka, T; Sasaki, N; Tanaka, J; Tanaka, T; Tanizaki, Y; Toujima, S; Utsunomiya, H; Utsunomiya, T; Yamamoto, M; Yukawa, K1
Aoki, D; Banno, K; Kisu, I; Kobayashi, Y; Masuda, K; Nomura, H; Susumu, N; Tominaga, E; Tsuji, K; Ueki, A; Yamagami, W; Yanokura, M1
Kiianitsa, K; Maizels, N1
Ikehata, M; Iwakawa, S; Ogawa, M; Tanaka, S; Ueda, K; Yamada, Y1
Fukuda, M; Hosokawa, M; Iwakawa, S; Masuda, A; Tanaka, S; Ueda, K1

Other Studies

12 other study(ies) available for camptothecin and decitabine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Synergistic cytotoxicity with 2'-deoxy-5-azacytidine and topotecan in vitro and in vivo.
    Cancer research, 1992, Apr-15, Volume: 52, Issue:8

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Azacitidine; Camptothecin; Colorectal Neoplasms; Decitabine; DNA Topoisomerases, Type I; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Female; Lethal Dose 50; Methylation; Mice; Mice, Inbred BALB C; Topotecan; Tumor Cells, Cultured

1992
Irinotecan inactivation is modulated by epigenetic silencing of UGT1A1 in colon cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Mar-15, Volume: 12, Issue:6

    Topics: Azacitidine; Camptothecin; Cell Line, Tumor; CpG Islands; Decitabine; DNA Methylation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glucuronides; Glucuronosyltransferase; HCT116 Cells; HT29 Cells; Humans; Hydroxamic Acids; Irinotecan

2006
Effect of combined therapy with low-dose 5-aza-2'-deoxycytidine and irinotecan on colon cancer cell line HCT-15.
    Annals of surgical oncology, 2007, Volume: 14, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Camptothecin; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA Methylation; Drug Therapy, Combination; Gene Expression Regulation, Neoplastic; Humans; In Situ Nick-End Labeling; Intracellular Signaling Peptides and Proteins; Irinotecan; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Promoter Regions, Genetic; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Tumor Suppressor Protein p14ARF

2007
DNA demethylation protects from cleavable complex stabilization and DNA strand breakage induced by the topoisomerase type I inhibitor camptothecin.
    Mutagenesis, 2009, Volume: 24, Issue:3

    Topics: Animals; Azacitidine; Camptothecin; CHO Cells; Comet Assay; Cricetinae; Cricetulus; Decitabine; DNA Breaks; DNA Methylation; DNA Topoisomerases, Type I; Electrophoresis, Gel, Pulsed-Field; Enzyme Inhibitors; Epigenesis, Genetic; Topoisomerase I Inhibitors

2009
Camptothecin-induced cell proliferation inhibition and apoptosis enhanced by DNA methyltransferase inhibitor, 5-aza-2'-deoxycytidine.
    Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Azacitidine; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Decitabine; DNA (Cytosine-5-)-Methyltransferases; Drug Synergism; Electrophoresis, Gel, Two-Dimensional; Enzyme-Linked Immunosorbent Assay; Galectin 1; Humans; Reverse Transcriptase Polymerase Chain Reaction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2009
Demethylation restores SN38 sensitivity in cells with acquired resistance to SN38 derived from human cervical squamous cancer cells.
    Oncology reports, 2012, Volume: 27, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis Regulatory Proteins; Azacitidine; Calcium-Calmodulin-Dependent Protein Kinases; Camptothecin; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Dealkylation; Death-Associated Protein Kinases; Decitabine; DNA Modification Methylases; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Promoter Regions, Genetic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Uterine Cervical Neoplasms

2012
Association of epigenetic inactivation of the WRN gene with anticancer drug sensitivity in cervical cancer cells.
    Oncology reports, 2012, Volume: 28, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents; Azacitidine; Camptothecin; Carcinoma, Squamous Cell; Cell Line, Tumor; Decitabine; DNA Methylation; Epigenesis, Genetic; Exodeoxyribonucleases; Female; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; RecQ Helicases; RNA, Small Interfering; Topoisomerase I Inhibitors; Uterine Cervical Neoplasms; Werner Syndrome Helicase

2012
A rapid and sensitive assay for DNA-protein covalent complexes in living cells.
    Nucleic acids research, 2013, Volume: 41, Issue:9

    Topics: Azacitidine; Camptothecin; Cell Line; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Adducts; DNA Topoisomerases, Type I; DNA-Binding Proteins; Humans; Immunoassay; Nuclear Proteins; Topoisomerase I Inhibitors

2013
Different effects of epigenetic modifiers on the cytotoxicity induced by 5-fluorouracil, irinotecan or oxaliplatin in colon cancer cells.
    Biological & pharmaceutical bulletin, 2014, Volume: 37, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Camptothecin; Cell Line, Tumor; Colonic Neoplasms; Decitabine; DNA; DNA Modification Methylases; Drug Synergism; Epigenesis, Genetic; Fluorouracil; HCT116 Cells; Histone Deacetylase Inhibitors; HT29 Cells; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin

2014
Monophosphorylation by deoxycytidine kinase affects apparent cellular uptake of decitabine in HCT116 colon cancer cells.
    Drug metabolism and pharmacokinetics, 2017, Volume: 32, Issue:6

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Camptothecin; Colonic Neoplasms; Cytarabine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; Equilibrative Nucleoside Transporter 1; Etoposide; Gemcitabine; HCT116 Cells; Humans; Irinotecan; Phosphorylation

2017