Page last updated: 2024-08-22

camptothecin and d-alpha tocopherol

camptothecin has been researched along with d-alpha tocopherol in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (28.57)29.6817
2010's14 (66.67)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Baltas, M; Bedos-Belval, F; Delomenède, M; Duran, H; Gornitzka, H; Negre-Salvayre, A; Rakotondramanana, DL; Rasoanaivo, P1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Anderson, K; Atkinson, J; Bandyopadhyay, A; Gilbert, BE; Kline, K; Knight, V; Lawson, KA; Sanders, BG; Simmons-Menchaca, M; Snyder, RM; Sun, LZ1
Elbayoumi, TA; Mu, L; Torchilin, VP1
Gao, Y; Li, LB; Zhai, G1
Sawant, RM; Sawant, RR; Torchilin, VP1
Li, LB; Wang, J; Wang, R1
Drozda, R; Grzegorczyk, K; Kontek, R; Sliwiński, M1
Anderson, K; Burris, HA; Jones, S; Marier, JF; Pheng, L; Porubek, D; Trinh, MM; Warner, S1
Ding, LY; Guo, M; Liu, YQ; Lu, Y; Ron, WT; Song, FF; Wang, Y; Yu, SQ1
Amano, T; Amatya, R; Black, KL; Hanson, CJ; Lee, BS; Pantoja, JL; Wang, HQ; Yen, A; Yoon, CW; Yu, JS1
Jakubczak, M; Kontek, R; Matlawska-Wasowska, K1
Bhori, M; Marar, T; Singh, K1
Hou, J; Lu, Y; Qi, SS; Rong, WT; Wang, DF; Xiao, Q; Xu, Q; You, J; Yu, SQ; Zhang, J1
Adamo, RF; Alferiev, IS; Brodeur, GM; Chorny, M; Croucher, JL; Fishbein, I; Iyer, R; Kolla, V; Levy, RJ; Mangino, JL; Zhang, K1
Bhori, M; Chilakapati, MK; Marar, T; Singh, K1
Ahmad, I; Eltahan, AS; Kaleem, QM; Li, C; Liang, XJ; Mozhi, A; Tuguntaev, RG; Wang, C; Yang, R1
Brüggemann, O; Hassel, AW; Mardare, CC; Quiñones, JP1
Fan, G; Jia, S; Lin, K; Shi, J; Yu, S; Yuan, J; Zhang, Y; Zhou, Q1
Chen, M; Chen, Z; Li, X; Wang, T; Xie, S; Zhang, Z1
Prud'homme, RK; Sinko, PJ; Wilson, BK1

Trials

1 trial(s) available for camptothecin and d-alpha tocopherol

ArticleYear
Pharmacokinetics of SN2310, an injectable emulsion that incorporates a new derivative of SN-38 in patients with advanced solid tumors.
    Journal of pharmaceutical sciences, 2011, Volume: 100, Issue:10

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Area Under Curve; Camptothecin; Chemistry, Pharmaceutical; Emulsions; Female; Half-Life; Humans; Infusions, Intravenous; Irinotecan; Male; Maximum Tolerated Dose; Metabolic Clearance Rate; Middle Aged; Neoplasms; Neutropenia; Succinates; Technology, Pharmaceutical; Vitamin E

2011

Other Studies

20 other study(ies) available for camptothecin and d-alpha tocopherol

ArticleYear
Synthesis of ferulic ester dimers, functionalisation and biological evaluation as potential antiatherogenic and antiplasmodial agents.
    Bioorganic & medicinal chemistry, 2007, Sep-15, Volume: 15, Issue:18

    Topics: Animals; Antioxidants; Atherosclerosis; Cell Survival; Coumaric Acids; Dimerization; Endothelium, Vascular; Esters; Humans; Leukemia P388; Lipoproteins, LDL; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Thiobarbituric Acid Reactive Substances

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Novel vitamin E analogue and 9-nitro-camptothecin administered as liposome aerosols decrease syngeneic mouse mammary tumor burden and inhibit metastasis.
    Cancer chemotherapy and pharmacology, 2004, Volume: 54, Issue:5

    Topics: Aerosols; alpha-Tocopherol; Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Female; Lymphatic Metastasis; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Vitamin E

2004
Mixed micelles made of poly(ethylene glycol)-phosphatidylethanolamine conjugate and d-alpha-tocopheryl polyethylene glycol 1000 succinate as pharmaceutical nanocarriers for camptothecin.
    International journal of pharmaceutics, 2005, Dec-08, Volume: 306, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Stability; Humans; Micelles; Nanostructures; Particle Size; Polyethylene Glycols; Solubility; Vitamin E

2005
Preparation and characterization of Pluronic/TPGS mixed micelles for solubilization of camptothecin.
    Colloids and surfaces. B, Biointerfaces, 2008, Jul-15, Volume: 64, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cell Line, Tumor; Cell Survival; Colorimetry; Drug Screening Assays, Antitumor; Female; Humans; Micelles; Molecular Structure; Poloxamer; Polyethylene Glycols; Solubility; Vitamin E

2008
Mixed PEG-PE/vitamin E tumor-targeted immunomicelles as carriers for poorly soluble anti-cancer drugs: improved drug solubilization and enhanced in vitro cytotoxicity.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2008, Volume: 70, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Carriers; Drug Stability; Hydrolysis; Mice; Micelles; Nucleosomes; Paclitaxel; Particle Size; Phosphatidylethanolamines; Polyethylene Glycols; Solubility; Technology, Pharmaceutical; Time Factors; Vitamin E

2008
Preparation and properties of hydroxycamptothecin-loaded nanoparticles made of amphiphilic copolymer and normal polymer.
    Journal of colloid and interface science, 2009, Aug-15, Volume: 336, Issue:2

    Topics: Camptothecin; Cell Line, Tumor; Drug Carriers; Humans; Micelles; Nanoparticles; Polyethylene Glycols; Polymers; Vitamin E

2009
Genotoxicity of irinotecan and its modulation by vitamins A, C and E in human lymphocytes from healthy individuals and cancer patients.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:2

    Topics: Adult; Antineoplastic Agents, Phytogenic; Ascorbic Acid; Camptothecin; Comet Assay; DNA Damage; DNA Repair; Female; Humans; Irinotecan; Lymphocytes; Male; Middle Aged; Mutagens; Vitamin A; Vitamin E

2010
Alpha-tocopheryl polyethylene glycol succinate-emulsified poly(lactic-co-glycolic acid) nanoparticles for reversal of multidrug resistance in vitro.
    Nanotechnology, 2012, Dec-14, Volume: 23, Issue:49

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Emulsions; Humans; Irinotecan; Lactic Acid; Materials Testing; Nanocapsules; Nanoparticles; Neoplasms, Experimental; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E

2012
Reactive oxygen species responsive nanoprodrug to treat intracranial glioblastoma.
    ACS nano, 2013, Apr-23, Volume: 7, Issue:4

    Topics: alpha-Tocopherol; Animals; Antioxidants; Brain Neoplasms; Camptothecin; Cell Line, Tumor; Glioblastoma; Mice; Nanocapsules; Prodrugs; Reactive Oxygen Species; Treatment Outcome

2013
The antioxidants, vitamin A and E but not vitamin C and melatonin enhance the proapoptotic effects of irinotecan in cancer cells in vitro.
    Toxicology in vitro : an international journal published in association with BIBRA, 2014, Volume: 28, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Ascorbic Acid; Camptothecin; Cell Line, Tumor; Coloring Agents; Flow Cytometry; HT29 Cells; Humans; In Situ Nick-End Labeling; Irinotecan; Melatonin; Necrosis; Vitamin A; Vitamin E

2014
α-Tocopherol mediated amelioration of camptothecin-induced free radical damage to avert cardiotoxicities.
    Human & experimental toxicology, 2015, Volume: 34, Issue:4

    Topics: Alanine Transaminase; Alkaline Phosphatase; alpha-Tocopherol; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Aspartate Aminotransferases; Camptothecin; Cardiotoxicity; Catalase; Free Radicals; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Lipid Peroxidation; Male; Myocardium; Rats, Wistar; Superoxide Dismutase; Topoisomerase I Inhibitors

2015
TPGS2k/PLGA nanoparticles for overcoming multidrug resistance by interfering mitochondria of human alveolar adenocarcinoma cells.
    ACS applied materials & interfaces, 2015, Feb-25, Volume: 7, Issue:7

    Topics: Adenosine Triphosphate; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Camptothecin; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Irinotecan; Lactic Acid; Mitochondria; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E

2015
Nanoparticle-mediated delivery of a rapidly activatable prodrug of SN-38 for neuroblastoma therapy.
    Biomaterials, 2015, Volume: 51

    Topics: alpha-Tocopherol; Animals; Camptothecin; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Humans; Irinotecan; Mice, Nude; Nanoparticles; Neuroblastoma; Particle Size; Prodrugs; Treatment Outcome

2015
Exploring the effect of vitamin E in cancer chemotherapy-A biochemical and biophysical insight.
    Journal of biophotonics, 2018, Volume: 11, Issue:9

    Topics: Antineoplastic Agents; Antioxidants; Apoptosis; Biophysical Phenomena; Camptothecin; DNA Fragmentation; Drug Interactions; HeLa Cells; Humans; Spectrum Analysis, Raman; Vitamin E

2018
Nrp-1 receptor targeting peptide-functionalized TPGS micellar nanosystems to deliver 10-hydroxycampothecin for enhanced cancer chemotherapy.
    International journal of pharmaceutics, 2018, Aug-25, Volume: 547, Issue:1-2

    Topics: A549 Cells; Apoptosis; Camptothecin; Cell Nucleus; DNA Topoisomerases, Type I; Drug Carriers; Drug Synergism; Hep G2 Cells; Humans; Inhibitory Concentration 50; MCF-7 Cells; Micelles; Mitochondria; Nanoparticles; Neoplasms; Neuropilin-1; Peptides; Polymers; Reactive Oxygen Species; Topoisomerase I Inhibitors; Vitamin E

2018
Testosterone- and vitamin-grafted cellulose ethers for sustained release of camptothecin.
    Carbohydrate polymers, 2019, Feb-15, Volume: 206

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cellulose; Delayed-Action Preparations; Drug Liberation; Ergocalciferols; Humans; Hydrophobic and Hydrophilic Interactions; MCF-7 Cells; Nanostructures; Particle Size; Testosterone; Vitamin E; Vitamins

2019
Specific Modification with TPGS and Drug Loading of Cyclodextrin Polyrotaxanes and the Enhanced Antitumor Activity Study in Vitro and in Vivo.
    ACS applied materials & interfaces, 2019, Dec-18, Volume: 11, Issue:50

    Topics: Animals; Anticarcinogenic Agents; Camptothecin; Cell Line, Tumor; Cellulose; Cyclodextrins; Drug Delivery Systems; Humans; Mice; Nanoparticles; Neoplasms; Rotaxanes; Vitamin E; Xenograft Model Antitumor Assays

2019
Synergistic antitumor efficacy of hybrid micelles with mitochondrial targeting and stimuli-responsive drug release behavior.
    Journal of materials chemistry. B, 2019, 03-07, Volume: 7, Issue:9

    Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Apoptosis; Camptothecin; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Liberation; Drug Synergism; Humans; Hyaluronic Acid; Mice; Micelles; Mitochondria; Neoplasms; Polyesters; Reactive Oxygen Species; Survival Rate

2019
Encapsulation and Controlled Release of a Camptothecin Prodrug from Nanocarriers and Microgels: Tuning Release Rate with Nanocarrier Excipient Composition.
    Molecular pharmaceutics, 2021, 03-01, Volume: 18, Issue:3

    Topics: alpha-Tocopherol; Camptothecin; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Stability; Excipients; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Lactates; Microgels; Nanoparticles; Polyesters; Polyethylene Glycols; Prodrugs; Solubility

2021