Page last updated: 2024-08-22

camptothecin and cytosine

camptothecin has been researched along with cytosine in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's2 (22.22)18.2507
2000's3 (33.33)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Horwitz, MS; Horwitz, SB; Hsu, KC; Liebeskind, D1
Bailly, C; Carrasco, C; Waring, MJ1
Bjornsti, MA; Essigmann, JM; Fertala, J; Park, HJ; Pommier, Y; Pourquier, P; Ueng, LM; Wang, D1
Cheng, YC; Dutschman, GE; Hsu, CH; Kim, TE; Park, SY1
Hoffman, RM1
Baker, SD; Chatelut, E; Mathijssen, RH; Rowinsky, EK; Sparreboom, A; Verweij, J; Wolff, AC1
Chang, Q; Chestnut, BA; Lesuisse, C; Martin, LJ; Price, A; Wong, M1
Coletta, A; Desideri, A1
Al Abo, M; Huang, SY; Kiselev, E; Liu, X; Plunkett, W; Pommier, Y; Rajapakse, VN; Sasanuma, H; Takeda, S1

Other Studies

9 other study(ies) available for camptothecin and cytosine

ArticleYear
Immunoreactivity to antinucleoside antibodies in camptothecin treated HeLa cells.
    Experimental cell research, 1974, Volume: 86, Issue:1

    Topics: Animals; Antibodies; Camptothecin; Cell Division; Cytosine; DNA, Single-Stranded; Fluorescence; HeLa Cells; Humans; Immunologic Techniques; Nucleic Acid Conformation; Nucleosides; Rabbits; Thymidine

1974
Substitution of 5-methylcytosines for cytosines enhances the stability of topoisomerase I-DNA complexes and modulates the sequence selectivity of camptothecin-induced DNA cleavage.
    FEBS letters, 1998, Mar-27, Volume: 425, Issue:2

    Topics: 5-Methylcytosine; Base Sequence; Camptothecin; Cytosine; DNA; DNA Topoisomerases, Type I; Humans; Molecular Sequence Data; Structure-Activity Relationship

1998
Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7, 8-dihydro-8-oxoguanine and 5-hydroxycytosine.
    The Journal of biological chemistry, 1999, Mar-26, Volume: 274, Issue:13

    Topics: Camptothecin; Cytosine; DNA; DNA Damage; DNA Topoisomerases, Type I; DNA-Binding Proteins; Guanosine; Humans; Kinetics; Molecular Structure; Mutation; Oligonucleotides; Oxidative Stress

1999
Synergistic antitumor activity of troxacitabine and camptothecin in selected human cancer cell lines.
    Molecular pharmacology, 2004, Volume: 66, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Cell Survival; Cytosine; Deoxycytidine Kinase; Dioxolanes; DNA Damage; Drug Screening Assays, Antitumor; Drug Synergism; Humans; KB Cells; Tumor Cells, Cultured

2004
Orthotopic metastatic (MetaMouse) models for discovery and development of novel chemotherapy.
    Methods in molecular medicine, 2005, Volume: 111

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Camptothecin; Cisplatin; Colonic Neoplasms; Cytosine; Disease Models, Animal; Drug Screening Assays, Antitumor; Female; Fluorouracil; Green Fluorescent Proteins; Humans; Immunotherapy; Interferons; Liposomes; Liver; Liver Neoplasms; Luminescent Proteins; Lung Neoplasms; Male; Metalloproteases; Mice; Mice, Inbred C57BL; Mice, Nude; Mice, Transgenic; Microscopy, Fluorescence; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Oligonucleotides, Antisense; Pancreatic Neoplasms; Prostatic Neoplasms; Red Fluorescent Protein

2005
Evaluation of alternate size descriptors for dose calculation of anticancer drugs in the obese.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Oct-20, Volume: 25, Issue:30

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Body Mass Index; Body Size; Body Surface Area; Body Weight; Camptothecin; Carboplatin; Cisplatin; Cytosine; Dioxolanes; Docetaxel; Doxorubicin; Humans; Irinotecan; Metabolic Clearance Rate; Obesity; Paclitaxel; Taxoids; Topotecan

2007
Epigenetic regulation of motor neuron cell death through DNA methylation.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Nov-16, Volume: 31, Issue:46

    Topics: 5-Methylcytosine; Age Factors; Amyloid Precursor Protein Secretases; Amyotrophic Lateral Sclerosis; Animals; Apoptosis; Aspartic Acid Endopeptidases; Camptothecin; Caspase 3; Cell Line, Transformed; Central Nervous System; Cytosine; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; Enzyme Inhibitors; Epigenomics; Gene Expression Regulation, Developmental; Green Fluorescent Proteins; Humans; Indoles; Mice; Mice, Transgenic; Motor Neurons; Mutation; Phthalimides; Propionates; RNA, Small Interfering; Sciatic Neuropathy; Superoxide Dismutase; Transfection; Tryptophan; Up-Regulation

2011
Role of the protein in the DNA sequence specificity of the cleavage site stabilized by the camptothecin topoisomerase IB inhibitor: a metadynamics study.
    Nucleic acids research, 2013, Volume: 41, Issue:22

    Topics: Base Sequence; Camptothecin; Computer Simulation; Cytosine; DNA; DNA Cleavage; DNA Topoisomerases, Type I; Models, Molecular; Thymine; Topoisomerase I Inhibitors

2013
TDP1 is Critical for the Repair of DNA Breaks Induced by Sapacitabine, a Nucleoside also Targeting ATM- and BRCA-Deficient Tumors.
    Molecular cancer therapeutics, 2017, Volume: 16, Issue:11

    Topics: Arabinonucleosides; BRCA2 Protein; Camptothecin; Colorectal Neoplasms; Cytarabine; Cytosine; DNA Breaks, Single-Stranded; DNA Damage; DNA Repair; DNA Replication; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Phosphoric Diester Hydrolases; Poly (ADP-Ribose) Polymerase-1

2017