camptothecin has been researched along with cycloheximide in 59 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (15.25) | 18.7374 |
| 1990's | 23 (38.98) | 18.2507 |
| 2000's | 22 (37.29) | 29.6817 |
| 2010's | 5 (8.47) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Kletzien, RF; Perdue, JF | 1 |
| Perdue, JF; Raizada, MK | 1 |
| Atherton, KT; Burke, DC | 1 |
| Kelly, DC; Lescott, T | 1 |
| Boyse, EA; Goldstein, G; Hammerling, U; Storrie, B | 1 |
| Clayton, DA; Lansman, RA | 1 |
| Eliceiri, GL | 1 |
| Beardmore, C; D'Arpa, P; Liu, LF | 1 |
| Kaufmann, SH | 1 |
| Coffee, KA; Cook, JA; Geisel, J; Halushka, PV; Wise, WC | 1 |
| Bosmann, HB; Morgan, HR; Myers, MW | 1 |
| Bhargava, G; Makman, MH | 1 |
| Kato, M; Takada, S; Takayama, S | 1 |
| Beidler, DR; Cheng, YC | 1 |
| Darzynkiewicz, Z; Gorczyca, W; Melamed, MR; Pizzolo, JG; Qiao, L | 1 |
| Bicknell, GR; Cohen, GM; Snowden, RT | 1 |
| Dean, N | 1 |
| Burnham, P; Louis, JC; Magal, E; Varon, S | 1 |
| Aldea, M; Comella, JX; Esquerda, JE; Sanz-Rodriguez, C | 1 |
| Darzynkiewicz, Z; Gong, J; Li, X | 1 |
| Gorczyca, W; Melamed, MR; Pizzolo, JG; Qiao, L | 1 |
| Bertoglio, J; Bréard, J; Issaad, C; Léglise, MC; Pallardy, M; Roger, R; Turhan, AG | 1 |
| Kato, M; Suzuki, A | 1 |
| Pommier, Y; Shao, RG; Shimizu, T | 1 |
| Piette, J; Piret, B | 1 |
| Mashima, T; Tsuruo, T | 1 |
| Liu, JH; Wang, FF; Wang, MC | 1 |
| Akiyama, Y; Furusho, K; Kataoka, A; Koishi, S; Kubota, M; Lin, YW; Sawada, M; Usami, I; Watanabe, Ki | 1 |
| Crissman, HA; Sailer, BL; Steinkamp, JA; Valdez, JG | 1 |
| Carabillò, M; Giuliano, M; Lauricella, M; Tesoriere, G; Vassallo, E; Vento, R | 1 |
| Adachi, K; Hirata, Y; Kiuchi, K | 1 |
| Bedner, E; Cheng, W; Darzynkiewicz, Z; Deptala, A; Li, X; Traganos, F | 1 |
| Darzynkiewicz, Z; Li, X | 1 |
| Cotter, TG; Knox, KA; McGahon, AJ; McKenna, SL; O'Gorman, DM | 1 |
| Darzynkiewicz, Z; Du, L; Li, X | 1 |
| Amstad, P; Bedner, E; Darzynkiewicz, Z; Smolewski, P | 1 |
| Bedner, E; Darzynkiewicz, Z; Halicka, HD | 1 |
| Cao, CX; Dimanche-Boitrel, MT; Nieves-Neira, W; Pommier, Y; Shao, RG; Solary, E | 1 |
| Mankouri, HW; Morgan, A | 1 |
| Bottero, V; Busuttil, V; Fischel, JL; Loubat, A; Magné, N; Milano, G; Peyron, JF | 1 |
| Heldebrant, MP; Kaufmann, SH; Meng, XW | 1 |
| Budd, RC; Ito, M; Kataoka, T; Nagai, K; Tschopp, J | 1 |
| Vigneswaran, N; Wu, J; Zacharias, W | 1 |
| Bhattacharya, S; Johnson, LR; Ray, RM | 2 |
| Buijtenhuijs, P; Haanen, C; Vermes, I; Wolbers, F | 1 |
| Andersson, H; van den Berg, A; Vermes, I; Wolbers, F | 1 |
| Hassel, BA; Hummer, BT; Li, X; Liu, M | 1 |
| de Léséleuc, L; Denis, F | 1 |
| Guo, XP; Nie, YC; Xia, QZ; Zhang, XL; Zhu, LF | 1 |
| Chen, GQ; Fliegauf, M; Lu, Y; Lübbert, M; Song, MG; Xu, YB; Yuan, TT | 1 |
| Bell, CW; Jiang, W; Pisetsky, DS; Reich, CF | 1 |
| Horváth, V; Ondrousková, E; Smarda, J; Soucek, K | 1 |
| Kopacek, J; Krizanova, O; Labudova, M; Lencesova, L; Ondrias, K; Pastorekova, S; Sirova, M | 1 |
| Avalos-Diaz, E; Bollain-y-Goytia, JJ; Daneri-Navarro, A; Herrera-Esparza, R; Ramírez-Sandoval, R; Vazquez-del-Mercado, M | 1 |
| Bohacova, V; Csaderova, L; Hudecova, S; Krizanova, O; Laukova, M; Lencesova, L; Sedlak, J | 1 |
| Ayusawa, D; En, A; Fujii, M; Miki, K; Takauji, Y | 1 |
59 other study(ies) available for camptothecin and cycloheximide
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Regulation of sugar transport in chick embryo fibroblasts and in fibroblasts transformed by a temperature-sensitive mutant of the Rous sarcoma virus.
Topics: Animals; Avian Sarcoma Viruses; Biological Transport, Active; Blood; Camptothecin; Carbohydrate Metabolism; Cell Transformation, Neoplastic; Chick Embryo; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Deoxyadenosines; Fibroblasts; Hexoses; Mutation; Temperature | 1976 |
Extent of mitogen receptor occupancy and modulation of mitogen receptor exposure: possible mechanisms for the regulation of cell growth.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Binding, Competitive; Biological Transport; Camptothecin; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Cycloheximide; Deoxyadenosines; Deoxyglucose; DNA Replication; Insulin; Kinetics; Mitogens; Phosphoric Diester Hydrolases; Receptor, Insulin; Thymidine | 1976 |
The effects of some different metabolic inhibitors on interferon superinduction.
Topics: Amanitins; Antimetabolites; Camptothecin; Cell Line; Cycloheximide; Dactinomycin; Humans; Interferons; Poly I-C; Protein Biosynthesis; RNA; RNA, Messenger | 1978 |
The effects of inhibitors of nucleic acid and protein synthesis on the replication of Spodoptera frugiperda nuclear polyhedrosis virus in cultured Spodoptera frugiperda cells.
Topics: Camptothecin; Cell Line; Cycloheximide; Cytarabine; Dactinomycin; Insect Viruses; Insecta; Puromycin; Rifampin; Virus Replication | 1976 |
Differentiation of thymocytes: evidence that induction of the surface phenotype requires transcription and translation.
Topics: Animals; Camptothecin; Cell Differentiation; Cycloheximide; Cytarabine; Dactinomycin; Deoxyadenosines; DNA; Hydroxyurea; In Vitro Techniques; Macromolecular Substances; Mice; Mice, Inbred Strains; Phenotype; Protein Biosynthesis; Protein Precursors; Puromycin; RNA; T-Lymphocytes; Thymus Extracts; Transcription, Genetic | 1976 |
Mitochondrial protein synthesis in mouse L-cells: effect of selective nicking of mitochondrial DNA.
Topics: Camptothecin; Chloramphenicol; Cycloheximide; DNA, Circular; DNA, Mitochondrial; Emetine; Ethidium; L Cells; Mitochondria; Molecular Weight; Protein Biosynthesis; Ribosomes; Transcription, Genetic | 1975 |
Some properties of the small homodisperse RNAs in the cytoplasm of HeLa cells.
Topics: Camptothecin; Cycloheximide; Cytoplasm; HeLa Cells; Pactamycin; Puromycin; RNA, Neoplasm | 1976 |
Involvement of nucleic acid synthesis in cell killing mechanisms of topoisomerase poisons.
Topics: Amsacrine; Animals; Antibiotics, Antineoplastic; Aphidicolin; Camptothecin; Cell Survival; Cricetinae; Cricetulus; Cycloheximide; Deoxyadenosines; Dichlororibofuranosylbenzimidazole; Diterpenes; DNA; Etoposide; Mutagens; Nucleic Acids; RNA; Time Factors; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 1990 |
Antagonism between camptothecin and topoisomerase II-directed chemotherapeutic agents in a human leukemia cell line.
Topics: Amsacrine; Aphidicolin; Blotting, Western; Camptothecin; Colony-Forming Units Assay; Cycloheximide; Daunorubicin; Deoxyadenosines; Dichlororibofuranosylbenzimidazole; Diterpenes; DNA Polymerase II; DNA Replication; Drug Synergism; Etoposide; Female; Humans; Leukemia, Promyelocytic, Acute; Mutagens; RNA; Topoisomerase II Inhibitors; Topotecan; Tumor Cells, Cultured | 1991 |
Endotoxin-induced arachidonic acid metabolism requires de novo protein synthesis and protein kinase C activation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Animals; Arachidonic Acid; Arachidonic Acids; Bacterial Toxins; Calcimycin; Camptothecin; Cell Survival; Cells, Cultured; Cycloheximide; Dactinomycin; Endotoxins; Enterotoxins; Enzyme Activation; Isoquinolines; Macrophages; Male; Piperazines; Protein Biosynthesis; Protein Kinase C; Rats; Staurosporine; Tetradecanoylphorbol Acetate; Thromboxane B2 | 1991 |
Synthesis of DNA, RNA protein and glycoprotein in mitochondria of cells transformed with Rous sarcoma viruses.
Topics: Animals; Avian Sarcoma Viruses; Camptothecin; Carbon Radioisotopes; Cell Transformation, Neoplastic; Chick Embryo; Cycloheximide; DNA, Neoplasm; Fibroblasts; Glucose; Glycoproteins; Leucine; Mannose; Mitochondria; Mutation; Neoplasm Proteins; Nucleoside Diphosphate Sugars; RNA, Neoplasm; Species Specificity; Temperature; Thymidine; Tritium; Uridine; Uridine Diphosphate Sugars | 1974 |
Effect of tunicamycin on the turnover of epidermal growth factor receptors in cultured calf aorta smooth muscle cells. Comparison with IMR-90 human lung fibroblasts.
Topics: Animals; Aorta, Thoracic; Binding Sites; Camptothecin; Cattle; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Epidermal Growth Factor; Fibroblasts; Glucosamine; Half-Life; Humans; Lung; Male; Mice; Muscle, Smooth, Vascular; Peptides; Tunicamycin | 1980 |
Comparison of lesions induced by intra-articular injections of quinolones and compounds damaging cartilage components in rat femoral condyles.
Topics: Administration, Oral; Animals; Bleomycin; Camptothecin; Cartilage, Articular; Chondroitin Lyases; Ciprofloxacin; Collagenases; Cycloheximide; Ethylmaleimide; Etoposide; Fluorescent Dyes; Hydroxyurea; Injections, Intra-Articular; Iodoacetates; Iodoacetic Acid; Irinotecan; Levofloxacin; Male; Ofloxacin; Papain; Rats; Rats, Sprague-Dawley; Rhodamines; Topoisomerase I Inhibitors | 1994 |
Camptothecin induction of a time- and concentration-dependent decrease of topoisomerase I and its implication in camptothecin activity.
Topics: Aphidicolin; Camptothecin; Cell Line; Colony-Forming Units Assay; Cycloheximide; DNA Adducts; DNA Damage; DNA Topoisomerases, Type I; Down-Regulation; Drug Resistance; Humans; Neoplasms; RNA; Topoisomerase I Inhibitors | 1995 |
Flow cytometric characterization of proliferation-associated nuclear antigen (p105) during the cell cycle in normal lymphocytes and promyelocytic leukemia cells (HL-60).
Topics: Camptothecin; Cell Cycle; Cycloheximide; DNA Damage; DNA, Neoplasm; Flow Cytometry; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Lymphocyte Activation; Lymphocytes; Methotrexate; Phytohemagglutinins; Proliferating Cell Nuclear Antigen; Teniposide; Vinblastine | 1995 |
Formation of high molecular mass DNA fragments is a marker of apoptosis in the human leukaemic cell line, U937.
Topics: Apoptosis; Biomarkers; Camptothecin; Cycloheximide; Dactinomycin; DNA Damage; DNA, Neoplasm; Emetine; Flow Cytometry; Humans; Leukemia, Promyelocytic, Acute; Molecular Weight; Neoplasm Proteins; Teniposide; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Zinc | 1994 |
Yeast glycosylation mutants are sensitive to aminoglycosides.
Topics: Camptothecin; Cycloheximide; Gentamicins; Glycosylation; Golgi Apparatus; Hygromycin B; Protein Processing, Post-Translational; Saccharomyces cerevisiae; Tunicamycin | 1995 |
Cooperative effects of ciliary neurotrophic factor and norepinephrine on tyrosine hydroxylase expression in cultured rat locus coeruleus neurons.
Topics: Adrenergic Fibers; Animals; Anisomycin; Camptothecin; Cell Differentiation; Cell Survival; Cells, Cultured; Ciliary Neurotrophic Factor; Cycloheximide; Dactinomycin; Drug Synergism; In Vitro Techniques; Locus Coeruleus; Nerve Tissue Proteins; Neurotransmitter Agents; Norepinephrine; Rats; Receptors, Adrenergic, alpha; Tyrosine 3-Monooxygenase | 1993 |
Skeletal muscle-derived trophic factors prevent motoneurons from entering an active cell death program in vitro.
Topics: Animals; Anisomycin; Apoptosis; Blotting, Southern; Camptothecin; Cell Communication; Cell Separation; Cell Survival; Centrifugation, Density Gradient; Chick Embryo; Chickens; Cycloheximide; Dactinomycin; Deoxyadenosines; DNA; Gene Expression; Immunohistochemistry; Metrizamide; Microscopy, Electron; Motor Neurons; Muscle Denervation; Muscles; Neurofilament Proteins; Puromycin; Spinal Cord | 1994 |
Different patterns of apoptosis of HL-60 cells induced by cycloheximide and camptothecin.
Topics: Apoptosis; Camptothecin; Cell Cycle; Cycloheximide; Electrophoresis, Agar Gel; Flow Cytometry; Humans; Leukemia, Promyelocytic, Acute; S Phase; Tosyllysine Chloromethyl Ketone; Tumor Cells, Cultured | 1993 |
p145 expression during the cell cycle in HL-60 cell line and normal human lymphocytes: effects of camptothecin, vinblastine, cycloheximide, actinomycin D, retinoic acid and DMSO.
Topics: Antigens, Nuclear; Antineoplastic Agents; Camptothecin; Cell Cycle; Cell Differentiation; Cycloheximide; Dactinomycin; Dimethyl Sulfoxide; Flow Cytometry; Humans; Lymphocyte Activation; Lymphocytes; Nuclear Proteins; Tretinoin; Tumor Cells, Cultured; Vinblastine | 1993 |
BCR-ABL does not prevent apoptotic death induced by human natural killer or lymphokine-activated killer cells.
Topics: Apoptosis; Camptothecin; Cycloheximide; Cytotoxicity, Immunologic; Dactinomycin; DNA Damage; DNA, Neoplasm; Etoposide; Fusion Proteins, bcr-abl; Hematopoietic Stem Cells; Humans; Hydrogen Peroxide; Killer Cells, Lymphokine-Activated; Killer Cells, Natural; Leukemia, Megakaryoblastic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Puromycin; Recombinant Fusion Proteins; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
Chemotherapeutic agent CPT-11 induces the new expression of the apoptosis initiator to the cytoplasm.
Topics: Amino Acid Sequence; Animals; Apoptosis; Camptothecin; Carcinoma, Hepatocellular; Caspase 1; Cell Extracts; Cell Nucleus; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoplasm; Dactinomycin; DNA; Humans; Irinotecan; Liver; Liver Neoplasms; Male; Molecular Sequence Data; Oligopeptides; Protein Synthesis Inhibitors; Rats; Tumor Cells, Cultured | 1996 |
Brefeldin A is a potent inducer of apoptosis in human cancer cells independently of p53.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Apoptosis; Brefeldin A; Camptothecin; Cell-Free System; Cyclin B; Cyclin B1; Cyclins; Cycloheximide; Cyclopentanes; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; HL-60 Cells; HT29 Cells; Humans; Mutation; Protein Synthesis Inhibitors; Staurosporine; Time Factors; Tumor Suppressor Protein p53 | 1996 |
Topoisomerase poisons activate the transcription factor NF-kappaB in ACH-2 and CEM cells.
Topics: Antioxidants; Camptothecin; Cell Line; Cycloheximide; Dactinomycin; Daunorubicin; DNA; DNA Damage; DNA Topoisomerases, Type I; Etoposide; HIV-1; NF-kappa B; Nucleic Acid Synthesis Inhibitors; Poly(ADP-ribose) Polymerase Inhibitors; Topoisomerase I Inhibitors; Transcriptional Activation; Virus Activation | 1996 |
[Involvement of ICE/CED 3 family proteases in antitumor agent-induced apoptosis].
Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Caspase 1; Cycloheximide; Cysteine Endopeptidases; Cytarabine; Doxorubicin; Humans; Leukemia; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1997 |
Protein tyrosine phosphatase-dependent activation of beta-globin and delta-aminolevulinic acid synthase genes in the camptothecin-induced IW32 erythroleukemia cell differentiation.
Topics: 5-Aminolevulinate Synthetase; Animals; Antineoplastic Agents, Phytogenic; Butyrates; Butyric Acid; Camptothecin; Cell Differentiation; Cycloheximide; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Leukemic; Globins; Leukemia, Erythroblastic, Acute; Mice; Protein Synthesis Inhibitors; Protein Tyrosine Phosphatases; Teniposide; Time Factors; Vanadates | 1997 |
Apoptosis-resistant phenotype selected by alternating exposure to camptothecin and etoposide.
Topics: Antineoplastic Agents; Apoptosis; Arabinofuranosylcytosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; bcl-X Protein; Calcimycin; Camptothecin; Clone Cells; Cycloheximide; Cytarabine; DNA Fragmentation; Drug Resistance, Neoplasm; Etoposide; HL-60 Cells; Humans; Hydroxyurea; Kinetics; Nucleosomes; Phenotype; Proto-Oncogene Proteins c-bcl-2; Ultraviolet Rays | 1997 |
Apoptosis induced with different cycle-perturbing agents produces differential changes in the fluorescence lifetime of DNA-bound ethidium bromide.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Camptothecin; Cell Cycle; Chromatin; Cycloheximide; DNA, Neoplasm; Enzyme Inhibitors; Ethidium; Flow Cytometry; Fluorescence; Fluorescent Dyes; Gamma Rays; Genistein; HL-60 Cells; Humans; Protein Synthesis Inhibitors | 1998 |
Induction of apoptosis in human retinoblastoma cells by topoisomerase inhibitors.
Topics: Amsacrine; Apoptosis; bcl-2-Associated X Protein; Camptothecin; Cell Survival; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; Dactinomycin; DNA Damage; DNA Topoisomerases, Type I; DNA, Neoplasm; Enzyme Inhibitors; Etoposide; Humans; Insulin-Like Growth Factor Binding Protein 3; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Retinal Neoplasms; Retinoblastoma; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1998 |
Phosphorylation and activation of p70 S6 kinase by manganese in PC12 cells.
Topics: Animals; Anisomycin; Antibodies; Antibody Specificity; Apoptosis; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Camptothecin; Cisplatin; Cycloheximide; DNA Fragmentation; Enzyme Activation; Immunoblotting; JNK Mitogen-Activated Protein Kinases; Manganese; Mitogen-Activated Protein Kinases; PC12 Cells; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-bcl-2; Rats; Ribosomal Protein S6 Kinases; Serine; Staurosporine; Threonine | 1998 |
Differences in induction of p53, p21WAF1 and apoptosis in relation to cell cycle phase of MCF-7 cells treated with camptothecin.
Topics: Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Camptothecin; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; DNA Replication; Enzyme Inhibitors; Female; Humans; Immunohistochemistry; Kinetics; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 1999 |
Cleavage of Poly(ADP-ribose) polymerase measured in situ in individual cells: relationship to DNA fragmentation and cell cycle position during apoptosis.
Topics: Apoptosis; Camptothecin; Cell Cycle; Cycloheximide; DNA Fragmentation; Enzyme Inhibitors; HL-60 Cells; Humans; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Topoisomerase I Inhibitors; Tumor Necrosis Factor-alpha | 2000 |
Sensitisation of HL60 human leukaemic cells to cytotoxic drug-induced apoptosis by inhibition of PI3-kinase survival signals.
Topics: Androstadienes; Antineoplastic Agents; Apigenin; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Camptothecin; Carrier Proteins; Cell Survival; Chromones; Cycloheximide; Dactinomycin; Dimerization; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Flavonoids; Genes, bcl-2; HL-60 Cells; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitoxantrone; Morpholines; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Sirolimus; Wortmannin | 2000 |
During apoptosis of HL-60 and U-937 cells caspases are activated independently of dissipation of mitochondrial electrochemical potential.
Topics: Apoptosis; Camptothecin; Caspases; Cycloheximide; Electrochemistry; Enzyme Activation; HL-60 Cells; Humans; Mitochondria; Poly(ADP-ribose) Polymerases; Tumor Necrosis Factor-alpha; U937 Cells | 2000 |
Activation of caspases measured in situ by binding of fluorochrome-labeled inhibitors of caspases (FLICA): correlation with DNA fragmentation.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Camptothecin; Caspase Inhibitors; Caspases; Cycloheximide; Cysteine Proteinase Inhibitors; DNA Fragmentation; Enzyme Inhibitors; Fluorescent Dyes; HL-60 Cells; Humans; In Situ Nick-End Labeling; Protein Synthesis Inhibitors; Tumor Necrosis Factor-alpha | 2000 |
Segregation of RNA and separate packaging of DNA and RNA in apoptotic bodies during apoptosis.
Topics: Apoptosis; Benzimidazoles; Bromouracil; Camptothecin; Coloring Agents; Cycloheximide; Dactinomycin; DNA; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Fluorescent Dyes; HL-60 Cells; Humans; Pyronine; RNA; Topoisomerase I Inhibitors; Tumor Necrosis Factor-alpha; Uridine | 2000 |
Activation of the Fas pathway independently of Fas ligand during apoptosis induced by camptothecin in p53 mutant human colon carcinoma cells.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Carrier Proteins; Colonic Neoplasms; Cycloheximide; DNA Fragmentation; Fas Ligand Protein; fas Receptor; Fas-Associated Death Domain Protein; Genes, p53; HT29 Cells; Humans; Membrane Glycoproteins; Mutation | 2001 |
The DNA helicase activity of yeast Sgs1p is essential for normal lifespan but not for resistance to topoisomerase inhibitors.
Topics: 4-Nitroquinoline-1-oxide; Camptothecin; Cycloheximide; DNA Helicases; Drug Resistance, Microbial; Ethylmaleimide; Hydroxyurea; Methyl Methanesulfonate; Mitoxantrone; Mutagenesis; RecQ Helicases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Topoisomerase I Inhibitors | 2001 |
Activation of nuclear factor kappaB through the IKK complex by the topoisomerase poisons SN38 and doxorubicin: a brake to apoptosis in HeLa human carcinoma cells.
Topics: Antibiotics, Antineoplastic; Apoptosis; Camptothecin; Cell Survival; Cycloheximide; DNA Damage; DNA-Binding Proteins; Doxorubicin; Enzyme Activation; Enzyme Inhibitors; Gene Expression; HeLa Cells; Humans; I-kappa B Kinase; I-kappa B Proteins; Irinotecan; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Serine-Threonine Kinases; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors | 2001 |
Phorbol 12-myristate 13-acetate inhibits death receptor-mediated apoptosis in Jurkat cells by disrupting recruitment of Fas-associated polypeptide with death domain.
Topics: Adaptor Proteins, Signal Transducing; Antigens, CD; Apoptosis; Apoptosis Regulatory Proteins; Binding Sites; Camptothecin; Carrier Proteins; Cell Line; Cycloheximide; Etoposide; fas Receptor; Fas-Associated Death Domain Protein; Gamma Rays; HSP90 Heat-Shock Proteins; Humans; Jurkat Cells; Kinetics; Membrane Glycoproteins; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Tetradecanoylphorbol Acetate; TNF-Related Apoptosis-Inducing Ligand; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Expression level of c-FLIP versus Fas determines susceptibility to Fas ligand-induced cell death in murine thymoma EL-4 cells.
Topics: Animals; Apoptosis; Camptothecin; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase Inhibitors; Cell Membrane; Cycloheximide; Down-Regulation; Doxorubicin; Etoposide; Fas Ligand Protein; fas Receptor; Gene Expression; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; Mice; Mitomycin; Protein Synthesis Inhibitors; Thymoma; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Up-Regulation | 2002 |
Upregulation of cystatin M during the progression of oropharyngeal squamous cell carcinoma from primary tumor to metastasis.
Topics: Apoptosis; Biomarkers, Tumor; Blotting, Western; Camptothecin; Carcinoma, Squamous Cell; Cathepsin B; Cell Line; Cycloheximide; Cystatin M; Cystatins; Cytotoxicity Tests, Immunologic; Disease Progression; DNA Fragmentation; Enzyme Inhibitors; Humans; Immunohistochemistry; In Situ Hybridization; Lymphatic Metastasis; Male; Middle Aged; Mouth Neoplasms; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2003 |
Prevention of TNF-alpha-induced apoptosis in polyamine-depleted IEC-6 cells is mediated through the activation of ERK1/2.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Biogenic Polyamines; Blotting, Western; Camptothecin; Caspases; Cell Line; Cycloheximide; Cytochromes c; DNA Fragmentation; DNA, Complementary; Enzyme Activation; Epithelial Cells; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Synthesis Inhibitors; Rats; Transfection; Tumor Necrosis Factor-alpha | 2004 |
Apoptotic cell death kinetics in vitro depend on the cell types and the inducers used.
Topics: Apoptosis; Camptothecin; Caspase Inhibitors; Cell Line; Cycloheximide; Endothelium, Vascular; Enzyme Inhibitors; Fluorescent Dyes; HL-60 Cells; Humans; Kinetics; Protein Synthesis Inhibitors; Tumor Necrosis Factor-alpha; Umbilical Veins | 2004 |
Apoptosis induced kinetic changes in autofluorescence of cultured HL60 cells-possible application for single cell analysis on chip.
Topics: Apoptosis; Camptothecin; Cycloheximide; Enzyme Inhibitors; Feasibility Studies; Flow Cytometry; Fluorescence; HL-60 Cells; Humans; Kinetics; Oligonucleotide Array Sequence Analysis; Protein Synthesis Inhibitors; Tumor Necrosis Factor-alpha; X-Rays | 2004 |
Camptothecin induces the ubiquitin-like protein, ISG15, and enhances ISG15 conjugation in response to interferon.
Topics: Antineoplastic Agents, Phytogenic; Blotting, Northern; Blotting, Western; Camptothecin; Cell Line, Tumor; Cell Nucleus; Cycloheximide; Cytokines; Dose-Response Relationship, Drug; Humans; Interferons; Protein Binding; Protein Processing, Post-Translational; RNA, Messenger; Signal Transduction; Time Factors; Topoisomerase I Inhibitors; Ubiquitins | 2004 |
Inhibition of apoptosis by Nur77 through NF-kappaB activity modulation.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Camptothecin; Cell Line; Cycloheximide; DNA Damage; DNA-Binding Proteins; Endoplasmic Reticulum; Etoposide; Fas Ligand Protein; Fibroblasts; Gene Expression Regulation; Humans; Inhibitor of Apoptosis Proteins; Membrane Glycoproteins; NF-kappa B; Nuclear Receptor Subfamily 4, Group A, Member 1; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Thapsigargin; Transcription Factors; Transfection; Tumor Necrosis Factors | 2006 |
[Spontaneous and induced programmed cell death in suspension cell cultures of cotton (Gossypium hirsutum L.)].
Topics: Apoptosis; Camptothecin; Cell Survival; Cells, Cultured; Cellular Senescence; Cycloheximide; DNA Fragmentation; DNA, Plant; Electrophoresis, Agar Gel; Fumonisins; Gossypium; Hot Temperature | 2005 |
Inducible expression of AML1-ETO fusion protein endows leukemic cells with susceptibility to extrinsic and intrinsic apoptosis.
Topics: Antibodies, Monoclonal; Apoptosis; Blotting, Western; Camptothecin; Cell Line, Tumor; Core Binding Factor Alpha 2 Subunit; Cycloheximide; Ecdysterone; fas Receptor; Flow Cytometry; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Humans; Oncogene Proteins, Fusion; Receptors, Tumor Necrosis Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RUNX1 Translocation Partner 1 Protein; Sensitivity and Specificity; Time Factors; Ultraviolet Rays | 2006 |
The extracellular release of HMGB1 during apoptotic cell death.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Line; Cycloheximide; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Etoposide; HMGB1 Protein; Humans; Hydroxamic Acids; Protein Synthesis Inhibitors; Staurosporine; Tumor Necrosis Factor-alpha | 2006 |
Alternative pathways of programmed cell death are activated in cells with defective caspase-dependent apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Autophagy; Blotting, Western; Camptothecin; Caspases; Cell Line, Transformed; Cell Transformation, Neoplastic; Chickens; Cycloheximide; Genes, myb; Humans; Microscopy, Fluorescence; Necrosis; Oxides; Signal Transduction; U937 Cells | 2008 |
Role of polyamines in p53-dependent apoptosis of intestinal epithelial cells.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Camptothecin; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Cycloheximide; DNA Damage; Enzyme Inhibitors; Epithelial Cells; Intestinal Mucosa; JNK Mitogen-Activated Protein Kinases; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Phosphorylation; Polyamines; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-mdm2; Rats; Signal Transduction; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53 | 2009 |
Apoptosis induced clustering of IP(3)R1 in nuclei of non-differentiated PC12 cells.
Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; bcl-2-Associated X Protein; Boron Compounds; Calcium; Camptothecin; Caspase 3; Cell Differentiation; Cell Nucleus; Cycloheximide; Dactinomycin; Dexamethasone; Etoposide; Inositol 1,4,5-Trisphosphate Receptors; PC12 Cells; Permeability; Rats; RNA, Messenger; Time Factors; Up-Regulation | 2011 |
Caspase 3 blocking avoids the expression of autoantigens triggered by apoptosis in neonatal Balb/c mice skin.
Topics: Amino Acid Chloromethyl Ketones; Animals; Animals, Newborn; Apoptosis; Autoantigens; Autoimmune Diseases; Biopsy; Camptothecin; Caspase Inhibitors; Cells, Cultured; Cycloheximide; Cysteine Proteinase Inhibitors; Drug Evaluation, Preclinical; Hydrogen Peroxide; In Situ Nick-End Labeling; Mercuric Chloride; Mice; Mice, Inbred BALB C; Organ Culture Techniques; Skin | 2011 |
Isoproterenol accelerates apoptosis through the over-expression of the sodium/calcium exchanger in HeLa cells.
Topics: Adrenergic beta-Agonists; Apoptosis; bcl-2-Associated X Protein; Camptothecin; Caspase 3; Cycloheximide; Gene Expression Regulation; HeLa Cells; Humans; Isoproterenol; Proto-Oncogene Proteins c-bcl-2; RNA, Messenger; Sodium-Calcium Exchanger | 2013 |
Combinatorial effects of continuous protein synthesis, ERK-signaling, and reactive oxygen species on induction of cellular senescence.
Topics: Antioxidants; Butadienes; Camptothecin; Cell Size; Cellular Senescence; Cycloheximide; DNA Damage; HeLa Cells; Humans; MAP Kinase Signaling System; Nitriles; Protein Biosynthesis; Reactive Oxygen Species; Thymidine | 2016 |