Page last updated: 2024-08-22

camptothecin and clopidogrel

camptothecin has been researched along with clopidogrel in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's8 (72.73)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Shi, D; Song, X; Yan, B; Yang, D; Yang, J1
Saito, Y; Sawada, J1
Bai, JP1
Feng, X; Gui, H; Hu, G; Li, Y; Luan, X; Mao, Z; Peng, Y; Shen, J; Yan, B; Yang, J1
Begg, EJ; Helsby, NA; Jensen, BP1
Chowbay, B; Sutiman, N1
Merali, Z; Paré, G; Ross, S1
Guo, QL; Hu, G; Huang, XF; Liu, W; Ning, R; Qi, Q; Wang, XP; Yang, J; Zhan, YR1
Guan, Y; Hafiz, MZ; He, S; Li, X; Liu, W; Wu, L; Xiong, J; Yan, B; Yang, J1
Paul, R; Paul, S1

Reviews

4 review(s) available for camptothecin and clopidogrel

ArticleYear
[Pharmacogenomics].
    Nihon rinsho. Japanese journal of clinical medicine, 2009, Volume: 67, Issue:6

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Camptothecin; Cetuximab; Clopidogrel; Humans; Irinotecan; Pharmacogenetics; Tegafur; Ticlopidine

2009
Ongoing challenges in drug interaction safety: from exposure to pharmacogenomics.
    Drug metabolism and pharmacokinetics, 2010, Volume: 25, Issue:1

    Topics: Administration, Oral; Camptothecin; Clopidogrel; Drug Evaluation; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inactivation, Metabolic; Injections, Intravenous; Irinotecan; Maximum Tolerated Dose; Membrane Transport Proteins; Models, Biological; Models, Statistical; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic; Ticlopidine

2010
Pharmacogenetics of drug-metabolizing enzymes: the prodrug hypothesis.
    Pharmacogenomics, 2012, Volume: 13, Issue:1

    Topics: Aryl Hydrocarbon Hydroxylases; Azathioprine; Camptothecin; Clopidogrel; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Enzymes; Glucuronosyltransferase; Humans; Inactivation, Metabolic; Irinotecan; Methyltransferases; Mixed Function Oxygenases; Prodrugs; Tamoxifen; Ticlopidine; Vitamin K Epoxide Reductases; Warfarin

2012
The pharmacogenetics of carboxylesterases: CES1 and CES2 genetic variants and their clinical effect.
    Drug metabolism and drug interactions, 2014, Volume: 29, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antiviral Agents; Aspirin; Benzimidazoles; Camptothecin; Carboxylesterase; Carboxylic Ester Hydrolases; Central Nervous System Stimulants; Clopidogrel; Dabigatran; Factor Xa Inhibitors; Genotype; Humans; Imidazolidines; Irinotecan; Isoenzymes; Methylphenidate; Oseltamivir; Platelet Aggregation Inhibitors; Polymorphism, Genetic; Pyridines; Ticlopidine

2014

Other Studies

7 other study(ies) available for camptothecin and clopidogrel

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interleukin-6 alters the cellular responsiveness to clopidogrel, irinotecan, and oseltamivir by suppressing the expression of carboxylesterases HCE1 and HCE2.
    Molecular pharmacology, 2007, Volume: 72, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Antiviral Agents; Camptothecin; Carboxylesterase; Carboxylic Ester Hydrolases; Carcinoma, Hepatocellular; Cell Line, Tumor; Cells, Cultured; Clopidogrel; Dose-Response Relationship, Drug; Female; Hepatocytes; Humans; Interleukin-6; Irinotecan; Liver Neoplasms; Male; Middle Aged; Oseltamivir; Platelet Aggregation Inhibitors; RNA, Messenger; Ticlopidine

2007
Lipopolysaccharide down-regulates carbolesterases 1 and 2 and reduces hydrolysis activity in vitro and in vivo via p38MAPK-NF-κB pathway.
    Toxicology letters, 2011, Mar-25, Volume: 201, Issue:3

    Topics: Animals; Blotting, Western; Camptothecin; Carboxylesterase; Carboxylic Ester Hydrolases; Cell Survival; Cells, Cultured; Clopidogrel; Down-Regulation; Enzyme Inhibitors; Genes, Reporter; Humans; Hydrolysis; Irinotecan; Lipopolysaccharides; Male; Mice; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Platelet Aggregation Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Subcellular Fractions; Ticlopidine; Transfection

2011
Pharmacogenetics and its relevance to clinical practice.
    Annals of the Academy of Medicine, Singapore, 2013, Volume: 42, Issue:9

    Topics: Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Asian People; Camptothecin; Carbamazepine; Clopidogrel; Cytochrome P-450 CYP2C19; Glucuronosyltransferase; HLA-A Antigens; HLA-B Antigens; Humans; Irinotecan; Platelet Aggregation Inhibitors; Stevens-Johnson Syndrome; Ticlopidine; Topoisomerase I Inhibitors

2013
Gambogic acid potentiates clopidogrel-induced apoptosis and attenuates irinotecan-induced apoptosis through down-regulating human carboxylesterase 1 and -2.
    Xenobiotica; the fate of foreign compounds in biological systems, 2016, Volume: 46, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Biotransformation; Camptothecin; Carboxylesterase; Clopidogrel; Down-Regulation; Irinotecan; Ticlopidine; Xanthones

2016
17β-estradiol suppresses carboxylesterases by activating c-Jun/AP-1 pathway in primary human and mouse hepatocytes.
    European journal of pharmacology, 2018, Jan-15, Volume: 819

    Topics: Animals; Camptothecin; Carboxylesterase; Carboxylic Ester Hydrolases; Clopidogrel; Enzyme Inhibitors; Estradiol; Female; Gene Expression Regulation, Enzymologic; Hepatocytes; Humans; Hydrolysis; Irinotecan; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred ICR; Receptors, Estrogen; Ticlopidine; Transcription Factor AP-1; Transcription, Genetic

2018
Exploration on the drug solubility enhancement in aqueous medium with the help of endo-functionalized molecular tubes: a computational approach.
    Physical chemistry chemical physics : PCCP, 2021, Sep-14, Volume: 23, Issue:34

    Topics: Albendazole; Camptothecin; Clopidogrel; Drug Industry; Fluorouracil; Indomethacin; Melphalan; Molecular Dynamics Simulation; ortho-Aminobenzoates; Solubility; Water

2021