Page last updated: 2024-08-22

camptothecin and chloroquine

camptothecin has been researched along with chloroquine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.26)18.7374
1990's2 (10.53)18.2507
2000's3 (15.79)29.6817
2010's11 (57.89)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Baltas, M; Bedos-Belval, F; Delomenède, M; Duran, H; Gornitzka, H; Negre-Salvayre, A; Rakotondramanana, DL; Rasoanaivo, P1
Castanys, S; Castanys-Muñoz, E; Gamarro, F; Pérez-Victoria, JM1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Bodo, B; Kamoga, D; Kasenene, J; Lacroix, D; Prado, S1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Angenot, L; Dive, G; Frédérich, M; Jansen, O; Nyemb, JN; Tchinda, AT; Tits, M1
Lee, H; Srivastava, V1
de Vera, IMS; Kamenecka, TM; Khan, P; Kojetin, DJ; Lin, H; Munoz-Tello, P1
Ademola, IK; Gordon, M; Karpoormath, R; Kayamba, F; Kushwaha, ND; Mahlalela, M; Malimabe, T; Mudau, PT; Nyamori, VO; Pooe, OJ; Shonhai, A; van Zyl, RL; Zininga, T1
Paparopoli, G; Sciarrino, E1
Jensen, PB; Sehested, M; Sorensen, M1
Duann, P; Lin, CT; Liu, LF; Sun, M; Zhang, H1
Li, R; Liu, WT; Song, JR; Sun, K; Wei, LX; Wu, MC; Zhang, JW; Zhang, SS; Zhao, QD; Zong, C1
Agostinis, P; Annaert, W; Boulanger, C; Carmeliet, P; De Bock, K; Dejana, E; Dewerchin, M; Garmyn, M; Georgiadou, M; Gerhardt, H; Ghesquière, B; Kuchnio, A; Maes, H; Moens, S; Nys, K; Peric, A; Quaegebeur, A; Radtke, F; Schoors, S; Vankelecom, H; Vinckier, S; Vion, AC; Wouters, J1
Duan, J; Liu, Q; Mu, H; Niu, H; Tang, J; Wang, D1
Chang, H; Chen, P; Li, B; Luo, X; Nie, P; Shi, X; Wu, B; Xu, W; Yu, X; Zou, Z1
Cao, L; Cheng, K; Su, Q; Zhang, X; Zhang, Y1

Other Studies

19 other study(ies) available for camptothecin and chloroquine

ArticleYear
Synthesis of ferulic ester dimers, functionalisation and biological evaluation as potential antiatherogenic and antiplasmodial agents.
    Bioorganic & medicinal chemistry, 2007, Sep-15, Volume: 15, Issue:18

    Topics: Animals; Antioxidants; Atherosclerosis; Cell Survival; Coumaric Acids; Dimerization; Endothelium, Vascular; Esters; Humans; Leukemia P388; Lipoproteins, LDL; Mice; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Thiobarbituric Acid Reactive Substances

2007
Characterization of an ABCG-like transporter from the protozoan parasite Leishmania with a role in drug resistance and transbilayer lipid movement.
    Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:10

    Topics: Aminoquinolines; Animals; Antiprotozoal Agents; ATP-Binding Cassette Transporters; Base Sequence; Biological Transport, Active; Chloroquine; DNA, Protozoan; Drug Resistance; Fluorescent Dyes; Genes, Protozoan; Humans; Leishmania infantum; Leishmaniasis, Visceral; Lipid Bilayers; Phosphorylcholine; Protozoan Proteins; Recombinant Proteins; Transformation, Genetic

2008
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Structure and in vitro antiparasitic activity of constituents of Citropsis articulata root bark.
    Journal of natural products, 2011, Oct-28, Volume: 74, Issue:10

    Topics: Alkaloids; Animals; Antimalarials; Chlorocebus aethiops; Coumarins; Glycosides; Inhibitory Concentration 50; Leishmania donovani; Parasitic Sensitivity Tests; Plant Roots; Plasmodium falciparum; Rutaceae; Uganda; Vero Cells

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Strychnobaillonine, an unsymmetrical bisindole alkaloid with an unprecedented skeleton from Strychnos icaja roots.
    Journal of natural products, 2014, Apr-25, Volume: 77, Issue:4

    Topics: Antimalarials; Cameroon; Carbazoles; Chloroquine; Indole Alkaloids; Inhibitory Concentration 50; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Plasmodium falciparum; Strychnine; Strychnos; Toxiferine

2014
Synthesis and bio-evaluation of novel quinolino-stilbene derivatives as potential anticancer agents.
    Bioorganic & medicinal chemistry, 2015, Dec-15, Volume: 23, Issue:24

    Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Neoplasms; Quinolines; Stilbenes; Tubulin; Tubulin Modulators

2015
Assessment of NR4A Ligands That Directly Bind and Modulate the Orphan Nuclear Receptor Nurr1.
    Journal of medicinal chemistry, 2020, 12-24, Volume: 63, Issue:24

    Topics: Amodiaquine; Animals; Cell Line; Chloroquine; Humans; Ligands; Nuclear Magnetic Resonance, Biomolecular; Nuclear Receptor Subfamily 4, Group A, Member 2; Phenylacetates; Protein Binding; Rats; Small Molecule Libraries; Transcription, Genetic

2020
Design and synthesis of quinoline-pyrimidine inspired hybrids as potential plasmodial inhibitors.
    European journal of medicinal chemistry, 2021, May-05, Volume: 217

    Topics: Antimalarials; Cell Survival; Dose-Response Relationship, Drug; Drug Design; HEK293 Cells; Humans; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Pyrimidines; Quinolines; Structure-Activity Relationship; Thermodynamics

2021
[Recent diagnostic and therapeutic acquisitions in malignant melanoma].
    Il Cancro, 1974, Volume: 27, Issue:1

    Topics: Antineoplastic Agents; Camptothecin; Chloroquine; Colchicine; Humans; Hydroxyurea; Imidazoles; Immunotherapy; Iodine Radioisotopes; Melanoma; Nitrosourea Compounds; Radionuclide Imaging; Triazenes

1974
pH-dependent regulation of camptothecin-induced cytotoxicity and cleavable complex formation by the antimalarial agent chloroquine.
    Biochemical pharmacology, 1997, Aug-01, Volume: 54, Issue:3

    Topics: Antimalarials; Camptothecin; Cell Death; Cell Survival; Chloroquine; DNA Damage; Drug Interactions; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Topoisomerase I Inhibitors; Tumor Cells, Cultured

1997
Plasmid linking number change induced by topoisomerase I-mediated DNA damage.
    Nucleic acids research, 1999, Jul-15, Volume: 27, Issue:14

    Topics: Animals; Camptothecin; Cell Line; Chloroquine; Chromatin; COS Cells; DNA Damage; DNA Topoisomerases, Type I; DNA, Superhelical; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fungal Proteins; Humans; Micrococcal Nuclease; Models, Genetic; Nucleic Acid Conformation; Plasmids; Simian virus 40; Time Factors; Topoisomerase I Inhibitors; Transfection; Ultraviolet Rays; Yeasts

1999
Autophagy inhibition switches low-dose camptothecin-induced premature senescence to apoptosis in human colorectal cancer cells.
    Biochemical pharmacology, 2014, Aug-01, Volume: 90, Issue:3

    Topics: Adenine; AMP-Activated Protein Kinases; Antineoplastic Agents; Apoptosis; Ataxia Telangiectasia Mutated Proteins; Autophagy; Camptothecin; Cell Line, Tumor; Cellular Senescence; Chloroquine; Class III Phosphatidylinositol 3-Kinases; Colorectal Neoplasms; Drug Resistance, Neoplasm; Enzyme Inhibitors; Humans; Lysosomes; Neoplasm Proteins; Osmolar Concentration; Signal Transduction; Tumor Suppressor Protein p53

2014
Tumor vessel normalization by chloroquine independent of autophagy.
    Cancer cell, 2014, Aug-11, Volume: 26, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Autophagy; Autophagy-Related Protein 5; Camptothecin; Cell Line, Tumor; Cell Proliferation; Chloroquine; Drug Synergism; Endothelial Cells; Endothelium, Vascular; Humans; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Microtubule-Associated Proteins; Neoplasm Invasiveness; Neovascularization, Pathologic; Receptor, Notch1; Skin Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays

2014
Autophagy promotes DNA-protein crosslink clearance.
    Mutation research. Genetic toxicology and environmental mutagenesis, 2016, Volume: 797

    Topics: Adenine; Animals; Antineoplastic Agents; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Protein 7; Camptothecin; Cell Line, Tumor; Cell Survival; Chloroquine; DNA Damage; Formaldehyde; Gene Silencing; Humans; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; RNA, Small Interfering; Sirolimus; Ubiquitin-Activating Enzymes; Ultraviolet Rays

2016
CQ synergistically sensitizes human colorectal cancer cells to SN-38/CPT-11 through lysosomal and mitochondrial apoptotic pathway via p53-ROS cross-talk.
    Free radical biology & medicine, 2017, Volume: 104

    Topics: Animals; Apoptosis; Autophagy; Camptothecin; Cell Line, Tumor; Cell Survival; Chloroquine; Colorectal Neoplasms; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Irinotecan; Lysosomes; Mice; Mitochondria; Reactive Oxygen Species; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2017
[Inhibition of autophagy initiation stage enhances camptothecin-induced apoptosis in NCI-H1975 cells].
    Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2017, Volume: 33, Issue:12

    Topics: Adenine; Apoptosis; Autophagy; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Chloroquine; Humans; Lung Neoplasms; Transforming Growth Factor beta1

2017