Page last updated: 2024-08-22

camptothecin and chitosan

camptothecin has been researched along with chitosan in 54 studies

Research

Studies (54)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (12.96)29.6817
2010's40 (74.07)24.3611
2020's7 (12.96)2.80

Authors

AuthorsStudies
Berrada, M; Dabbarh, F; Gupta, A; Lehnert, S; Owusu, A; Serreqi, A1
Apirakaramwong, A; Chaidedgumjorn, A; Chirachanchai, S; Choochottiros, C; Ngawhirunpat, T; Opanasopit, P; Phongying, S; Rojanarata, T1
Ding, Y; Ping, Q; Yu, LL; Zhang, C1
Chirachanchai, S; Choochottiros, C; Ngawhirunpat, T; Opanasopit, P; Rojanarata, T1
Bae, SM; Jeong, SY; Jo, HG; Kim, IS; Kim, K; Kim, YS; Kwon, IC; Lee, S; Min, KH; Park, K; Park, RW1
Gaud, R; Shende, P1
Chirachanchai, S; Ngawhirunpat, T; Opanasopit, P; Ruktanonchai, U; Wasanasuk, K; Wonglertnirant, N; Yoksan, R1
Duan, K; Huang, J; Li, Y; Liu, S; Tang, X; Wang, D; Yu, J; Zhang, X1
Barrett, A; Dehghani, F; Foster, NR; Ji, C; Poole-Warren, LA1
Du, YZ; Hu, FQ; Wang, L; Yuan, H; Zhou, JP; Zhou, YY1
Guo, G; Kong, X; Li, X; Luo, F; Qian, Z; Shi, S; Wang, Y; Wei, Y; Zhang, J; Zhao, X1
Chen, X; Li, X; Li, Z; Liu, X; Qian, Z; Wei, Y; Yi, T; Zhao, X; Zhong, Q; Zhou, L; Zhou, S1
Chen, XC; He, X; Li, XY; Li, ZY; Liu, XP; Qian, ZY; Wang, YM; Wei, YQ; Yi, T; Zhao, X; Zhong, Q; Zhou, LN; Zhou, ST1
Chen, X; Du, L; He, X; Li, X; Li, Z; Qian, Z; Wei, Y; Wen, Y; Zhao, X; Zhou, L1
Bao, H; Gan, LH; Li, J; Li, L; Pan, Y; Ping, Y; Sahoo, NG; Wu, T1
Beninati, S; Desideri, A; Galbiati, A; Mattioli, P; Morozzo Della Rocca, B; Paradossi, G; Tabolacci, C1
Cao, Z; Li, X; Li, Z; Lin, H; Qian, Z; Wei, Y; Xu, Y; Zhao, Y1
Cheng, T; Guan, XM; Lan, JF; Liu, XY; Shen, JM; Zhang, HX1
Juntapram, K; Muangsin, N; Praphairaksit, N; Siraleartmukul, K1
Huang, F; Jing, GL; Qu, JB; Shao, HH1
Lin, MH; Liu, TY; Wu, MY; Yang, FY1
Cao, J; Cui, S; Gu, Y; Qian, Z; Zhu, H1
Chen, C; Song, F; Tang, DL; Wang, XL; Wang, YZ1
Guo, M; Hou, J; Lu, Y; Rong, WT; Wang, DF; Wang, Y; Xu, Q; Yu, SQ1
Girish, SN; Marina, K; Matapady, NH; Prabhakara, P; Shama, KP; Zenia, T1
Huang, W; Huang, X; Meng, L; Wang, D; Yan, D; Zhu, X1
Ge, L; Wang, J; Wang, Y; Xu, H; Zhu, J1
Guo, X; Han, J; Hou, ZQ; Wang, YG1
Hsiao, CS; Hsiao, MH; Liu, DM; Tung, TH1
Amini, M; Atyabi, F; Azhdarzadeh, M; Dinarvand, M; Ghasemi, Z; Mollarazi, E; Sayari, E1
Mao, S; Shi, C; Sun, CC; Sun, Y; Tian, Y; Zhu, C1
Cheng, G; Gao, Y; Liu, J; Liu, Y; Piao, H; Tang, B; Tian, Y; Wang, L; Xu, C; Zou, M1
Atyabi, F; Dinarvand, M; Dinarvand, R; Esmaeili, A; Kiani, M; Mirzaie, Z; Mirzazadeh, F; Soleimani, M1
Chen, HP; Chen, MH; Liu, TY; Tung, FI1
Amini, M; Atyabi, F; Azhdarzadeh, M; Dinarvand, R; Esfandyari-Manesh, M; Hosseinzadeh, H; Mirzaie, ZH; Ostad, SN; Vafaei, SY; Varnamkhasti, BS1
Agarwal, P; He, X; Lu, X; Wang, H; Xu, RX; Yu, J; Zhao, S1
Gou, M; Li, X; Li, Z; Peng, F; Qian, Z; Sun, L1
Fan, Z; Hou, Z; Jiang, Y; Li, Y; Lu, Y; Wu, S; Yang, X1
Li, J; Oupický, D; Ping, Q; Qiao, H; Su, Z; Sun, M; Xie, Y; Zhang, C1
Kandasamy, R; Natesan, S; Palanichamy, R; Ponnusamy, C; Sugumaran, A; Thiagarajan, V1
Gao, Z; Li, Z; Wang, P; Yan, J1
Almeida, A; Campana-Filho, SP; Colnago, LA; Facchinatto, WM; Prezotti, FG; Sarmento, B; Silva, DS1
Afkham, A; Afkham, NM; Aghebati-Maleki, L; Ahmadi, M; Akbarzadeh, P; Dolati, S; Jadidi-Niaragh, F; Sadreddini, S; Siahmansouri, H; Younesi, V; Yousefi, M1
Abnous, K; Alibolandi, M; Amel Farzad, S; Kalalinia, F; Mohammadi, M; Ramezani, M; Taghdisi, SM1
Ahmad, N; Ahmad, R; Alam, MA; Jalees Ahmad, F; Umar, S1
Dahiru, NS; Dramou, P; Fizir, M; He, H; Itatahine, A; Mehdi, YA; Taleb, A; Wei, L; Zhang, J1
Bermejo, M; Gonzalez-Alvarez, I; Gonzalez-Alvarez, M; Martínez-Martínez, M; Merino, V; Rodríguez-Berna, G1
Almeida, A; Andrade, F; Araújo, M; Gonçalves, H; Lúcio, M; Novoa-Carballal, R; Reis, RL; Sarmento, B; Schwartz, S1
Almeida, A; Caraballo, I; Casas, M; Linares, V; Mora-Castaño, G; Sarmento, B1
Li, Y; Miao, J; Shao, Y; Si, H; Sun, Y; Xu, Y; Yang, Y1
Huang, X; Song, Y; Wang, B; Zhang, J; Zhang, T1
Almeida, A; Castro, F; Lúcio, M; Resende, C; Sarmento, B; Schwartz, S1
Fernanda Rodero, C; Franciane Leão, A; Isadora Boni, F; Noronha Ferreira, N; Palmira Daflon Gremião, M; Stringhetti Ferreira Cury, B1
Li, J; Qin, J; Sun, M; Wang, D; Zhen, Y1

Other Studies

54 other study(ies) available for camptothecin and chitosan

ArticleYear
A novel non-toxic camptothecin formulation for cancer chemotherapy.
    Biomaterials, 2005, Volume: 26, Issue:14

    Topics: Absorbable Implants; Animals; Antineoplastic Agents, Phytogenic; Biocompatible Materials; Camptothecin; Cell Line, Tumor; Chitosan; Diffusion; Drug Implants; Fibrosarcoma; Materials Testing; Mice; Mice, Inbred C3H; Treatment Outcome

2005
Incorporation of camptothecin into N-phthaloyl chitosan-g-mPEG self-assembly micellar system.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2006, Volume: 64, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Chemistry, Pharmaceutical; Chitosan; Chromatography, Gel; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Stability; Hydrolysis; Kinetics; Lactones; Micelles; Models, Chemical; Polyethylene Glycols; Serum Albumin; Serum Albumin, Bovine; Solubility; Time Factors

2006
Polymeric micelle systems of hydroxycamptothecin based on amphiphilic N-alkyl-N-trimethyl chitosan derivatives.
    Colloids and surfaces. B, Biointerfaces, 2007, Apr-01, Volume: 55, Issue:2

    Topics: Camptothecin; Chitosan; Chromatography, High Pressure Liquid; Drug Delivery Systems; Drug Stability; Hydrophobic and Hydrophilic Interactions; Micelles; Microscopy, Electron, Transmission; Molecular Structure; Particle Size; Pharmaceutical Preparations; Solubility

2007
Camptothecin-incorporating N-phthaloylchitosan-g-mPEG self-assembly micellar system: effect of degree of deacetylation.
    Colloids and surfaces. B, Biointerfaces, 2007, Oct-15, Volume: 60, Issue:1

    Topics: Acetylation; Antineoplastic Agents, Phytogenic; Camptothecin; Chitosan; Drug Delivery Systems; Micelles; Nanostructures; Polyethylene Glycols

2007
Hydrophobically modified glycol chitosan nanoparticles-encapsulated camptothecin enhance the drug stability and tumor targeting in cancer therapy.
    Journal of controlled release : official journal of the Controlled Release Society, 2008, May-08, Volume: 127, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Drug Stability; Humans; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Lactones; Mice; Mice, Nude; Nanoparticles; Neoplasms; Tissue Distribution; Tumor Burden; Xenograft Model Antitumor Assays

2008
Formulation and comparative characterization of chitosan, gelatin, and chitosan-gelatin-coated liposomes of CPT-11-HCl.
    Drug development and industrial pharmacy, 2009, Volume: 35, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Chemistry, Pharmaceutical; Chitosan; Cholesterol; Chromatography, High Pressure Liquid; Drug Carriers; Drug Compounding; Drug Stability; Electrochemistry; Freeze Fracturing; Gelatin; Irinotecan; Liposomes; Phosphatidylcholines

2009
Incorporation methods for cholic acid chitosan-g-mPEG self-assembly micellar system containing camptothecin.
    Colloids and surfaces. B, Biointerfaces, 2009, Nov-01, Volume: 74, Issue:1

    Topics: Camptothecin; Chitosan; Cholic Acid; Drug Delivery Systems; Half-Life; Hydrogen-Ion Concentration; Hydrolysis; Kinetics; Lactones; Methyl Ethers; Micelles; Microscopy, Electron, Transmission; Particle Size; Polyethylene Glycols

2009
Fabrication of cationic nanomicelle from chitosan-graft-polycaprolactone as the carrier of 7-ethyl-10-hydroxy-camptothecin.
    Colloids and surfaces. B, Biointerfaces, 2010, Apr-01, Volume: 76, Issue:2

    Topics: Camptothecin; Cations; Chitosan; Drug Carriers; Irinotecan; Micelles; Nanostructures; Particle Size; Polyesters; Surface Properties

2010
The development of a dense gas solvent exchange process for the impregnation of pharmaceuticals into porous chitosan.
    International journal of pharmaceutics, 2010, May-31, Volume: 391, Issue:1-2

    Topics: Camptothecin; Carbon Dioxide; Chemistry, Pharmaceutical; Chitosan; Crystallization; Drug Carriers; Drug Compounding; Griseofulvin; Hydrogels; Particle Size; Porosity; Pressure; Solubility; Solvents

2010
Preparation and pharmacodynamics of stearic acid and poly (lactic-co-glycolic acid) grafted chitosan oligosaccharide micelles for 10-hydroxycamptothecin.
    International journal of pharmaceutics, 2010, Jun-30, Volume: 393, Issue:1-2

    Topics: Antineoplastic Agents, Phytogenic; Biological Transport; Camptothecin; Carbodiimides; Cell Survival; Chemistry, Pharmaceutical; Chitosan; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Stability; Hep G2 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Micelles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Stearic Acids; Technology, Pharmaceutical

2010
A novel composite hydrogel based on chitosan and inorganic phosphate for local drug delivery of camptothecin nanocolloids.
    Journal of pharmaceutical sciences, 2011, Volume: 100, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Chemical Phenomena; Chemistry, Pharmaceutical; Chitosan; Colloids; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Stability; Female; Humans; Hydrogels; Kinetics; Mice; Mice, Inbred BALB C; Nanostructures; Ovarian Neoplasms; Phosphates

2011
In vivo antitumor and antimetastatic activities of camptothecin encapsulated with N-trimethyl chitosan in a preclinical mouse model of liver cancer.
    Cancer letters, 2010, Nov-01, Volume: 297, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Carcinoma, Hepatocellular; Cell Proliferation; Cell Survival; Chemistry, Pharmaceutical; Chitosan; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Female; Liver Neoplasms; Lymphangiogenesis; Lymphatic Metastasis; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; RNA, Messenger; Time Factors; Tumor Burden; Vascular Endothelial Growth Factor D

2010
Anti-tumor activity of N-trimethyl chitosan-encapsulated camptothecin in a mouse melanoma model.
    Journal of experimental & clinical cancer research : CR, 2010, Jun-17, Volume: 29

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Line, Tumor; Cell Proliferation; Chitosan; Drug Carriers; Female; Immunoenzyme Techniques; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; Solubility; Tissue Distribution; Xenograft Model Antitumor Assays

2010
The antitumor and antimetastatic effects of N-trimethyl chitosan-encapsulated camptothecin on ovarian cancer with minimal side effects.
    Oncology reports, 2010, Volume: 24, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Line, Tumor; Chitosan; Disease Models, Animal; Female; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Nude; Neovascularization, Pathologic; Ovarian Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; Xenograft Model Antitumor Assays

2010
Chitosan-functionalized graphene oxide as a nanocarrier for drug and gene delivery.
    Small (Weinheim an der Bergstrasse, Germany), 2011, Jun-06, Volume: 7, Issue:11

    Topics: Camptothecin; Cell Death; Cell Survival; Chitosan; DNA; Drug Carriers; Drug Delivery Systems; Electrophoresis, Agar Gel; Gene Transfer Techniques; Graphite; HeLa Cells; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Microscopy, Atomic Force; Nanoparticles; Plasmids; Potentiometry; Spectrophotometry, Ultraviolet; Static Electricity; Thermogravimetry; Transfection

2011
Targeting tumor cells through chitosan-folate modified microcapsules loaded with camptothecin.
    Bioconjugate chemistry, 2011, Jun-15, Volume: 22, Issue:6

    Topics: Adsorption; Animals; Antineoplastic Agents; Camptothecin; Capsules; Cell Proliferation; Chitosan; Drug Carriers; Drug Delivery Systems; Drug Screening Assays, Antitumor; Folic Acid; HeLa Cells; Humans; Mice; Molecular Structure; NIH 3T3 Cells; Structure-Activity Relationship; Surface Properties; Tumor Cells, Cultured

2011
Camptothecin nanocolloids based on N,N,N-trimethyl chitosan: efficient suppression of growth of multiple myeloma in a murine model.
    Oncology reports, 2012, Volume: 27, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Cell Proliferation; Cell Survival; Chemistry, Pharmaceutical; Chitosan; Colloids; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Stability; Female; Mice; Mice, Inbred BALB C; Multiple Myeloma; Nanoparticles; Solubility; Time Factors; Topoisomerase I Inhibitors; Tumor Burden

2012
Luminescent/magnetic hybrid nanoparticles with folate-conjugated peptide composites for tumor-targeted drug delivery.
    Bioconjugate chemistry, 2012, May-16, Volume: 23, Issue:5

    Topics: Antineoplastic Agents, Phytogenic; Cadmium Compounds; Camptothecin; Cell Line, Tumor; Chitosan; Drug Delivery Systems; Folic Acid; Humans; Luminescence; Luminescent Agents; Magnetite Nanoparticles; Micelles; Neoplasms; Oligopeptides; Quantum Dots; Tellurium

2012
Electrosprayed polyelectrolyte complexes between mucoadhesive N,N,N,-trimethylchitosan-homocysteine thiolactone and alginate/carrageenan for camptothecin delivery.
    Carbohydrate polymers, 2012, Nov-06, Volume: 90, Issue:4

    Topics: Alginates; Antineoplastic Agents, Phytogenic; Camptothecin; Carrageenan; Chitosan; Drug Carriers; Drug Delivery Systems; Electrochemical Techniques; Glucuronic Acid; Hexuronic Acids; Homocysteine; Microscopy, Electron, Scanning; Mucins; Polymers; Spectroscopy, Fourier Transform Infrared; Tissue Adhesives

2012
PEG-chitosan-coated iron oxide nanoparticles with high saturated magnetization as carriers of 10-hydroxycamptothecin: preparation, characterization and cytotoxicity studies.
    Colloids and surfaces. B, Biointerfaces, 2013, Feb-01, Volume: 102

    Topics: Camptothecin; Cell Survival; Chitosan; Drug Carriers; Ferric Compounds; Hep G2 Cells; Humans; Nanoparticles; Polyethylene Glycols

2013
A novel ultrasound-triggered drug vehicle with multimodal imaging functionality.
    Acta biomaterialia, 2013, Volume: 9, Issue:3

    Topics: Animals; Camptothecin; Cattle; Chitosan; Dextrans; Drug Carriers; Magnetic Fields; Magnetic Resonance Imaging; Magnetite Nanoparticles; Microbubbles; Nanoparticles; Rats; Rats, Sprague-Dawley; Serum Albumin, Bovine; Ultrasonics; X-Ray Diffraction

2013
Enhanced tumor targeting and antitumor efficacy via hydroxycamptothecin-encapsulated folate-modified N-succinyl-N'-octyl chitosan micelles.
    Journal of pharmaceutical sciences, 2013, Volume: 102, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Delivery Systems; Folic Acid; Humans; Mice; Mice, Nude; Micelles; Neoplasms; Rats

2013
A pH-responsive chitosan-b-poly(p-dioxanone) nanocarrier: formation and efficient antitumor drug delivery.
    Nanotechnology, 2013, Apr-12, Volume: 24, Issue:14

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line; Chitosan; Dioxanes; Drug Delivery Systems; HeLa Cells; Humans; Hydrogen-Ion Concentration; Mice; Micelles; Nanocapsules; Nanotechnology; Polymers

2013
Mechanisms of chitosan-coated poly(lactic-co-glycolic acid) nanoparticles for improving oral absorption of 7-ethyl-10-hydroxycamptothecin.
    Nanotechnology, 2013, Jun-21, Volume: 24, Issue:24

    Topics: Absorption; Animals; Caco-2 Cells; Calorimetry, Differential Scanning; Camptothecin; Cell Death; Chitosan; Coated Materials, Biocompatible; Coumarins; Enterocytes; HT29 Cells; Humans; Intestines; Irinotecan; Kinetics; Lactic Acid; Male; Nanoparticles; Particle Size; Perfusion; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Rhodamine 123; Spectroscopy, Fourier Transform Infrared; Static Electricity; X-Ray Diffraction

2013
Preparation and evaluation of lipid vesicles of camptothecin as targeted drug delivery system.
    Pakistan journal of pharmaceutical sciences, 2013, Volume: 26, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chitosan; Drug Delivery Systems; Drug Stability; Female; Liposomes; Rats; Rats, Sprague-Dawley; Solubility

2013
Chitosan-based nanocarriers with pH and light dual response for anticancer drug delivery.
    Biomacromolecules, 2013, Aug-12, Volume: 14, Issue:8

    Topics: Animals; Antineoplastic Agents; Camptothecin; Carbohydrate Conformation; Carbohydrate Sequence; Cell Proliferation; Cell Survival; Chitosan; Drug Screening Assays, Antitumor; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; MCF-7 Cells; Mice; Micelles; Molecular Sequence Data; Nanocapsules; NIH 3T3 Cells; Nitrobenzenes; Photochemical Processes

2013
Investigation of dual-sensitive nanogels based on chitosan and N-isopropylacrylamide and its intelligent drug delivery of 10-hydroxycamptothecine.
    Drug delivery, 2015, Volume: 22, Issue:6

    Topics: Acrylamides; Acrylic Resins; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Line; Chitosan; Drug Delivery Systems; Drug Liberation; Dynamic Light Scattering; Gels; Humans; Hydrogen-Ion Concentration; Molecular Weight; Technology, Pharmaceutical; Temperature

2015
Synthesis and evaluation of hydroxycamptothecin-encapsulated chitosan nanospheres for the treatment of liver cancer.
    Technology in cancer research & treatment, 2015, Volume: 14, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chitosan; Disease Models, Animal; Drug Compounding; Drug Liberation; Hep G2 Cells; Humans; Liver Neoplasms; Nanospheres; Xenograft Model Antitumor Assays

2015
Nano-hybrid carboxymethyl-hexanoyl chitosan modified with (3-aminopropyl)triethoxysilane for camptothecin delivery.
    Carbohydrate polymers, 2012, Jun-20, Volume: 89, Issue:2

    Topics: Antineoplastic Agents; Camptothecin; Cell Line; Cell Survival; Chitosan; Drug Carriers; Drug Liberation; Humans; Nanoparticles; Propylamines; Silanes

2012
MUC1 aptamer conjugated to chitosan nanoparticles, an efficient targeted carrier designed for anticancer SN38 delivery.
    International journal of pharmaceutics, 2014, Oct-01, Volume: 473, Issue:1-2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Aptamers, Nucleotide; Camptothecin; Cell Survival; Chitosan; CHO Cells; Cricetinae; Cricetulus; Drug Carriers; Esters; HT29 Cells; Humans; Irinotecan; Molecular Targeted Therapy; Mucin-1; Nanoparticles

2014
Designing micellar nanocarriers with improved drug loading and stability based on solubility parameter.
    Molecular pharmaceutics, 2015, Mar-02, Volume: 12, Issue:3

    Topics: Biopharmaceutics; Camptothecin; Chitosan; Drug Delivery Systems; Drug Stability; Humans; In Vitro Techniques; Micelles; Microscopy, Electron, Transmission; Models, Molecular; Molecular Dynamics Simulation; Molecular Structure; Nanocapsules; Particle Size; Solubility

2015
Comparison of two self-assembled macromolecular prodrug micelles with different conjugate positions of SN38 for enhancing antitumor activity.
    International journal of nanomedicine, 2015, Volume: 10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Chitosan; Irinotecan; Macromolecular Substances; Male; Mice; Mice, Inbred BALB C; Micelles; Particle Size; Prodrugs; Rats; Rats, Sprague-Dawley; Solubility; Xenograft Model Antitumor Assays

2015
Oral delivery of nanoparticles containing anticancer SN38 and hSET1 antisense for dual therapy of colon cancer.
    International journal of biological macromolecules, 2015, Volume: 78

    Topics: Administration, Oral; Animals; Camptothecin; Cell Line, Tumor; Chitosan; Colonic Neoplasms; Disease Models, Animal; Drug Carriers; Drug Liberation; Drug Stability; Histone-Lysine N-Methyltransferase; Humans; Irinotecan; Mice; Nanoparticles; Oligonucleotides, Antisense; Spectroscopy, Fourier Transform Infrared; Xenograft Model Antitumor Assays

2015
A novel micelle-forming material used for preparing a theranostic vehicle exhibiting enhanced in vivo therapeutic efficacy.
    Journal of medicinal chemistry, 2015, May-14, Volume: 58, Issue:9

    Topics: Animals; Antineoplastic Agents; Camptothecin; Carbocyanines; Cell Line, Tumor; Chitosan; Delayed-Action Preparations; Drug Carriers; Female; Ferric Compounds; Fluorescence; Fluorescent Dyes; Folic Acid; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Magnetic Fields; Magnets; Mice, Nude; Micelles; Nanoparticles; Sonication

2015
Protein corona hampers targeting potential of MUC1 aptamer functionalized SN-38 core-shell nanoparticles.
    International journal of pharmaceutics, 2015, Oct-15, Volume: 494, Issue:1

    Topics: Animals; Apoptosis; Aptamers, Nucleotide; Calorimetry, Differential Scanning; Camptothecin; Cell Line, Tumor; Cell Survival; Chitosan; Cricetinae; Drug Carriers; Drug Liberation; Humans; Hyaluronic Acid; Irinotecan; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Mucin-1; Nanoparticles; Particle Size; Protein Corona

2015
Hyaluronic acid-decorated dual responsive nanoparticles of Pluronic F127, PLGA, and chitosan for targeted co-delivery of doxorubicin and irinotecan to eliminate cancer stem-like cells.
    Biomaterials, 2015, Volume: 72

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Chitosan; Doxorubicin; Drug Delivery Systems; Drug Liberation; Drug Resistance, Neoplasm; Endocytosis; Humans; Hyaluronic Acid; Hydrogen-Ion Concentration; Intracellular Space; Irinotecan; Lactic Acid; Male; Mice, Nude; Nanoparticles; Neoplastic Stem Cells; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spheroids, Cellular; Tissue Distribution

2015
Improving Antitumor Activity with N-Trimethyl Chitosan Entrapping Camptothecin in Colon Cancer and Lung Cancer.
    Journal of nanoscience and nanotechnology, 2015, Volume: 15, Issue:9

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chitosan; Colonic Neoplasms; Drug Carriers; Female; Lung Neoplasms; Mice; Mice, Inbred BALB C

2015
A green approach to dual-drug nanoformulations with targeting and synergistic effects for cancer therapy.
    Drug delivery, 2017, Volume: 24, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Camptothecin; Cell Survival; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Combinations; Drug Compounding; Drug Stability; Drug Synergism; Female; Green Chemistry Technology; HeLa Cells; Humans; Methotrexate; Mice, Inbred BALB C; Mice, Nude; Nanomedicine; Nanoparticles; Solubility; Technology, Pharmaceutical; Tissue Distribution; Tumor Burden; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays

2017
Arginine-Modified Nanostructured Lipid Carriers with Charge-Reversal and pH-Sensitive Membranolytic Properties for Anticancer Drug Delivery.
    Advanced healthcare materials, 2017, Volume: 6, Issue:8

    Topics: Animals; Antineoplastic Agents; Arginine; Camptothecin; Chitosan; Drug Carriers; Hep G2 Cells; Humans; Hydrogen-Ion Concentration; Liver Neoplasms, Experimental; Male; Mice; Nanostructures; Rats; Rats, Sprague-Dawley; Xenograft Model Antitumor Assays

2017
Chitosan stabilized camptothecin nanoemulsions: Development, evaluation and biodistribution in preclinical breast cancer animal mode.
    International journal of biological macromolecules, 2017, Volume: 104, Issue:Pt B

    Topics: Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Camptothecin; Cell Line, Tumor; Cell Survival; Chitosan; Disease Models, Animal; Drug Carriers; Drug Evaluation, Preclinical; Drug Liberation; Drug Stability; Emulsions; Female; Humans; MCF-7 Cells; Mice; Nanoparticles; Tissue Distribution; Xenograft Model Antitumor Assays

2017
Irinotecan and 5-fluorouracil-co-loaded, hyaluronic acid-modified layer-by-layer nanoparticles for targeted gastric carcinoma therapy.
    Drug design, development and therapy, 2017, Volume: 11

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Delivery Systems; Fluorouracil; Humans; Hyaluronic Acid; Irinotecan; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Stomach Neoplasms

2017
Self-aggregates of 3,6-O,O'-dimyristoylchitosan derivative are effective in enhancing the solubility and intestinal permeability of camptothecin.
    Carbohydrate polymers, 2017, Dec-01, Volume: 177

    Topics: Caco-2 Cells; Camptothecin; Chitosan; Drug Carriers; Humans; Micelles; Particle Size; Permeability; Solubility

2017
Chitosan (CMD)-mediated co-delivery of SN38 and Snail-specific siRNA as a useful anticancer approach against prostate cancer.
    Pharmacological reports : PR, 2018, Volume: 70, Issue:3

    Topics: Antineoplastic Agents; Cadherins; Camptothecin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Chitosan; Claudin-1; Drug Delivery Systems; Humans; Irinotecan; Male; Nanoparticles; Prostatic Neoplasms; RNA, Small Interfering; Snail Family Transcription Factors

2018
Tetrac-decorated chitosan-coated PLGA nanoparticles as a new platform for targeted delivery of SN38.
    Artificial cells, nanomedicine, and biotechnology, 2018, Volume: 46, Issue:sup2

    Topics: Animals; Antineoplastic Agents; Biological Transport; Camptothecin; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Liberation; Female; Humans; Integrin alphaVbeta3; Mice; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer; Thyroxine; Xenograft Model Antitumor Assays

2018
Improvement of oral efficacy of Irinotecan through biodegradable polymeric nanoparticles through in vitro and in vivo investigations.
    Journal of microencapsulation, 2018, Volume: 35, Issue:4

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Brain; Caco-2 Cells; Camptothecin; Chitosan; Drug Carriers; Humans; Intestinal Absorption; Irinotecan; Lactic Acid; Male; MCF-7 Cells; Nanoparticles; Neoplasms; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar

2018
Folic acid-conjugated chitosan oligosaccharide-magnetic halloysite nanotubes as a delivery system for camptothecin.
    Carbohydrate polymers, 2018, Oct-01, Volume: 197

    Topics: Antineoplastic Agents; Camptothecin; Cell Proliferation; Cell Survival; Chitosan; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Screening Assays, Antitumor; Folic Acid; Humans; Nanotubes; Oligosaccharides; Structure-Activity Relationship; Tumor Cells, Cultured

2018
Covalently crosslinked organophosphorous derivatives-chitosan hydrogel as a drug delivery system for oral administration of camptothecin.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2019, Volume: 136

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Caco-2 Cells; Camptothecin; Chitosan; Cross-Linking Reagents; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Male; Organophosphorus Compounds; Rats; Rats, Wistar

2019
Novel amphiphilic chitosan micelles as carriers for hydrophobic anticancer drugs.
    Materials science & engineering. C, Materials for biological applications, 2020, Volume: 112

    Topics: Antineoplastic Agents; Camptothecin; Chitosan; Drug Carriers; Drug Liberation; Gastric Acid; Hydrophobic and Hydrophilic Interactions; Kinetics; Micelles; Oleic Acid; Particle Size; Polyethylene Glycols; Thermodynamics

2020
3D printed systems for colon-specific delivery of camptothecin-loaded chitosan micelles.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2021, Volume: 167

    Topics: Administration, Oral; Antineoplastic Agents, Phytogenic; Caco-2 Cells; Camptothecin; Chitosan; Colon; Drug Carriers; Drug Delivery Systems; Drug Liberation; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Micelles; Polymers; Printing, Three-Dimensional

2021
Chitosan functionalized graphene oxide nanocomposites for fluorescence imaging of apoptotic processes and targeted anti-inflammation study.
    Carbohydrate polymers, 2021, Oct-01, Volume: 269

    Topics: Animals; Anti-Inflammatory Agents; Antibodies; Apoptosis; Camptothecin; Cattle; Cell Line; Chitosan; Drug Carriers; Drug Liberation; Emodin; Fluorescent Dyes; Graphite; Humans; Inflammation; Lipopolysaccharides; Mammary Glands, Human; Mastitis; Mice; Nanocomposites; Toll-Like Receptor 4

2021
Combating liver cancer through GO-targeted biomaterials.
    Biomedical materials (Bristol, England), 2021, 09-06, Volume: 16, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Chitosan; Graphite; Hep G2 Cells; Humans; Hyaluronic Acid; Liver Neoplasms; Nanoparticle Drug Delivery System; Solubility

2021
Oral delivery of camptothecin-loaded multifunctional chitosan-based micelles is effective in reduce colorectal cancer.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 349

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Caco-2 Cells; Camptothecin; Cell Line, Tumor; Chitosan; Colorectal Neoplasms; Drug Carriers; Humans; Micelles; Oleic Acid

2022
Multilayered polymer coating modulates mucoadhesive and biological properties of camptothecin-loaded lipid nanocapsules.
    International journal of pharmaceutics, 2023, Mar-25, Volume: 635

    Topics: Camptothecin; Chitosan; Lipids; Nanocapsules; Polymers

2023
A ROS-response hyaluronic acid-coated/chitosan polymer prodrug for enhanced tumour targeting efficacy of SN38.
    Journal of drug targeting, 2023, Volume: 31, Issue:6

    Topics: Animals; Camptothecin; Cell Line, Tumor; Chitosan; Hyaluronic Acid; Irinotecan; Mice; Neoplasms; Polymers; Prodrugs; Reactive Oxygen Species; Tumor Microenvironment

2023