Page last updated: 2024-08-22

camptothecin and carmustine

camptothecin has been researched along with carmustine in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.00)18.7374
1990's6 (20.00)18.2507
2000's15 (50.00)29.6817
2010's6 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Corbett, TH; Edelstein, M; Hazeldine, ST; Horwitz, JP; Kushner, J; Palomino, E; Paluch, J; Polin, L; White, K1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bergevin, PR; Blom, J; Tormey, DC1
Gang, M; Kline, I; Sirica, AE; Venditti, JM; Woodman, RJ1
Moertel, CG1
Berger, NA; Chatterjee, S; Cheng, MF1
Ali-Osman, F; Bigner, DD; Colvin, OM; Dolan, ME; Friedman, HS; Griffith, OW; Kaufmann, SH; Moschel, RC; Schold, SC1
Anderson, RC; Babel, KM; Brat, DJ; Brem, H; Ewend, MG; Pinn, ML; Tabassi, K; Tyler, BM; Williams, JA1
Bigner, DD; Coggins, CA; Colvin, OM; Elion, GB; Friedman, HS; Hare, CB; Houghton, PJ; Keir, S1
Brem, H; Ewend, MG; Sampath, P; Tyler, BM; Williams, JA1
Bartussek, C; Naumann, U; Weller, M1
Bigner, DD; Castellino, RC; Elion, GB; Friedman, HS; Houghton, PJ; Johnson, SP; Keir, ST1
Prados, M1
Chang, JY; Chen, LT; Juang, SH; Liu, JF; Liu, TW1
Bigner, DD; Colvin, OM; Dolan, ME; Friedman, HS; Houghton, PJ; Keir, S; Moschel, RC; Pegg, AE1
Alderson, LM; Amundson, E; Brem, H; Colvin, M; Sampath, P; Tyler, BM; Wall, ME; Wani, MC; Weingart, JD1
Baldwin, AS; Cusack, JC; Ewend, MG; Weaver, KD; Yeyeodu, S1
Friedman, HS; Houghton, PJ; Keir, ST1
Affronti, ML; Allen, D; Badruddoja, M; Bigner, DD; Bohlin, C; Dowell, JM; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Jackson, S; Provenzale, JM; Quinn, JA; Reardon, DA; Rich, JN; Sampson, JH; Silverman, S; Tourt-Uhlig, S; Vredenburgh, J; Walker, A; Ziegler, K1
Affronti, ML; Allen, D; Bigner, DD; Bohlin, C; Friedman, AH; Friedman, HS; Gururangan, S; Herndon, JE; Jackson, S; Lentz, C; Provenzale, JM; Quinn, JA; Reardon, DA; Rich, JN; Sampson, JH; Schweitzer, H; Tourt-Uhlig, S; Vredenburgh, J; Walker, A; Ziegler, K1
Brem, H; Moriarity, JL; Renard, VM; Storm, PB; Tyler, B; Weingart, JD; Wilentz, RE1
Amistà, P; Basso, U; Brandes, AA; Ermani, M; Monfardini, S; Nicolardi, L; Reni, M; Sotti, G; Tosoni, A; Valduga, F1
Barger, G; Brem, H; Brem, S; Fruehauf, JP; Huang, W; Parker, R; Sloan, A1
Chang, JY; Chen, LT; Kuo, CC; Liu, JF; Ma, LC1
Ames, MM; Arusell, R; Ballman, KV; Brown, PD; Buckner, JC; Galanis, E; Giannini, C; Hammack, JE; Jaeckle, KA; McGovern, RM; Morton, RF; Nikcevich, DA; Reid, JM; Safgren, SL; Schomberg, PJ; Uhm, JH; Wender, DB1
Almubarak, M; Altaha, R; Khan, M; Nagaiah, G1
Audrain, O; Carsin, B; Gedouin, D; Hamlat, A; Lecouillard, I; Lesimple, T; Louvel, G; Mesbah, H; Quillien, V; Riffaud, L; Vauleon, E1
Chang, TM; Kau, YC; Liu, SJ; Su, CH; Tseng, YY; Wang, YC; Yang, TC1

Reviews

4 review(s) available for camptothecin and carmustine

ArticleYear
Guide to the use of cancer chemotherapeutic agents.
    Modern treatment, 1972, Volume: 9, Issue:2

    Topics: Alkylating Agents; Allopurinol; Antibiotics, Antineoplastic; Antimetabolites; Antineoplastic Agents; Asparaginase; Azaserine; Azauridine; Bleomycin; Camptothecin; Carmustine; Cell Division; Cyclophosphamide; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Fluorouracil; Humans; Kinetics; Neoplasms; Nitrogen Mustard Compounds; Procarbazine; Triazines; Vincristine

1972
Temozolomide in combination with other cytotoxic agents.
    Seminars in oncology, 2001, Volume: 28, Issue:4 Suppl 13

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carmustine; Central Nervous System Neoplasms; Clinical Trials as Topic; Dacarbazine; Drug Implants; Glioma; Humans; Irinotecan; Temozolomide

2001
The emerging role of irinotecan (CPT-11) in the treatment of malignant glioma in brain tumors.
    Cancer, 2003, May-01, Volume: 97, Issue:9 Suppl

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Carmustine; Clinical Trials as Topic; Dacarbazine; Glioma; Humans; Irinotecan; Neoplasm Recurrence, Local; Temozolomide

2003
Cerebrospinal fluid leak during treatment with bevacizumab and irinotecan after carmustine-impregnated wafers placement in patients with grade 2 oligodendroglioma and glioblastoma multiforme: report of two cases and review of literature.
    Cancer investigation, 2010, Volume: 28, Issue:10

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothecin; Carmustine; Drug Implants; Female; Glioblastoma; Humans; Irinotecan; Male; Neoplasm Recurrence, Local; Oligodendroglioma

2010

Trials

4 trial(s) available for camptothecin and carmustine

ArticleYear
Phase 2 trial of BCNU plus irinotecan in adults with malignant glioma.
    Neuro-oncology, 2004, Volume: 6, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Camptothecin; Carmustine; Confidence Intervals; Female; Glioblastoma; Glioma; Humans; Irinotecan; Male; Middle Aged; Oligodendroglioma

2004
Phase 1 trial of irinotecan plus BCNU in patients with progressive or recurrent malignant glioma.
    Neuro-oncology, 2004, Volume: 6, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Astrocytoma; Camptothecin; Carmustine; Female; Glioblastoma; Glioma; Humans; Irinotecan; Male; Middle Aged; Neoplasm Recurrence, Local; Oligodendroglioma

2004
Second-line chemotherapy with irinotecan plus carmustine in glioblastoma recurrent or progressive after first-line temozolomide chemotherapy: a phase II study of the Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO).
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Dec-01, Volume: 22, Issue:23

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Carmustine; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Electroencephalography; Female; Follow-Up Studies; Glioblastoma; Humans; Irinotecan; Italy; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Salvage Therapy; Survival Analysis; Temozolomide; Treatment Outcome

2004
Phase II NCCTG trial of RT + irinotecan and adjuvant BCNU plus irinotecan for newly diagnosed GBM.
    Journal of neuro-oncology, 2010, Volume: 99, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Brain Neoplasms; Camptothecin; Carmustine; Cohort Studies; Disease-Free Survival; Dose-Response Relationship, Drug; Female; Glioblastoma; Humans; Irinotecan; Male; Middle Aged; Radiotherapy; Statistics as Topic; Time Factors; Young Adult

2010

Other Studies

22 other study(ies) available for camptothecin and carmustine

ArticleYear
Design, synthesis, and biological evaluation of analogues of the antitumor agent, 2-(4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy)propionic acid (XK469).
    Journal of medicinal chemistry, 2001, May-24, Volume: 44, Issue:11

    Topics: Animals; Antineoplastic Agents; Drug Design; Drug Screening Assays, Antitumor; Humans; Mice; Quinoxalines; Stereoisomerism; Structure-Activity Relationship; Transplantation, Heterologous; Tumor Cells, Cultured

2001
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
The enhanced therapeutic effect of cis-platinum (II) diamminodichloride against L1210 leukemia when combined with cyclophosphamide or 1,2-bis(3,5-dioxopiperazine-1-yl)propane or several other antitumor agents.
    Chemotherapy, 1973, Volume: 18, Issue:3

    Topics: Amines; Animals; Antineoplastic Agents; Azacitidine; Camptothecin; Carmustine; Chlorides; Cyclophosphamide; Cytarabine; Drug Synergism; Emetine; Fluorouracil; Ketones; Leukemia L1210; Male; Methotrexate; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Piperazines; Platinum; Propane; Time Factors

1973
Cancer of the gastrointestinal tract. Chemotherapy.
    JAMA, 1974, Jun-03, Volume: 228, Issue:10

    Topics: Antineoplastic Agents; Camptothecin; Carmustine; Cyclohexanes; Cyclophosphamide; Drug Therapy, Combination; Fluorometholone; Fluorouracil; Humans; Hydroxyurea; Mitomycins; Nitrosourea Compounds; Remission, Spontaneous; Stomach Neoplasms; Streptonigrin; Time Factors

1974
Schedule-dependent cytotoxicity of topotecan alone and in combination chemotherapy regimens.
    Oncology research, 1994, Volume: 6, Issue:6

    Topics: Alkylating Agents; Animals; Antineoplastic Combined Chemotherapy Protocols; Aphidicolin; Camptothecin; Carmustine; Cell Cycle; Cell Death; Cell Line; Cisplatin; Cricetinae; Cricetulus; DNA Damage; DNA Repair; DNA, Neoplasm; Doxorubicin; Drug Synergism; Etoposide; Fibroblasts; Hydroxyurea; Lung; Melphalan; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Topotecan

1994
Elevated DNA polymerase alpha, DNA polymerase beta, and DNA topoisomerase II in a melphalan-resistant rhabdomyosarcoma xenograft that is cross-resistant to nitrosoureas and topotecan.
    Cancer research, 1994, Jul-01, Volume: 54, Issue:13

    Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Camptothecin; Carmustine; DNA Polymerase I; DNA Polymerase II; DNA Topoisomerases, Type II; Drug Resistance; Drug Screening Assays, Antitumor; Female; Humans; Male; Melphalan; Mice; Mice, Inbred BALB C; Mice, Nude; Rhabdomyosarcoma; Topotecan; Transferases; Transplantation, Heterologous

1994
Local delivery of chemotherapy and concurrent external beam radiotherapy prolongs survival in metastatic brain tumor models.
    Cancer research, 1996, Nov-15, Volume: 56, Issue:22

    Topics: Animals; Antineoplastic Agents; Brain; Brain Neoplasms; Camptothecin; Carboplatin; Carcinoma; Carcinoma, Lewis Lung; Carmustine; Colonic Neoplasms; Combined Modality Therapy; Female; Humans; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Transplantation; Polymers; Radiotherapy Dosage; Tumor Cells, Cultured

1996
Enhancement of irinotecan (CPT-11) activity against central nervous system tumor xenografts by alkylating agents.
    Cancer chemotherapy and pharmacology, 1998, Volume: 41, Issue:6

    Topics: Adult; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Busulfan; Camptothecin; Carmustine; Child; Cyclophosphamide; Drug Combinations; Drug Interactions; Enzyme Inhibitors; Ependymoma; Female; Glioma; Humans; Irinotecan; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Topoisomerase I Inhibitors; Transplantation, Heterologous

1998
Local delivery of chemotherapy prolongs survival in experimental brain metastases from breast carcinoma.
    Neurosurgery, 1998, Volume: 43, Issue:5

    Topics: Animals; Antineoplastic Agents; Brain; Brain Neoplasms; Camptothecin; Carboplatin; Carmustine; Combined Modality Therapy; Cranial Irradiation; Delayed-Action Preparations; Drug Implants; Female; Injections, Intralesional; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Polymers; Tumor Cells, Cultured

1998
Accumulation of mutant p53(V143A) modulates the growth, clonogenicity, and radiochemosensitivity of malignant glioma cells independent of endogenous p53 status.
    Experimental cell research, 1999, Dec-15, Volume: 253, Issue:2

    Topics: Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin; Carmustine; Cell Death; Cell Division; Cisplatin; Clone Cells; Combined Modality Therapy; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Gene Expression Regulation, Neoplastic; Genes, Dominant; Glioma; Humans; In Vitro Techniques; Paclitaxel; Point Mutation; Radiotherapy; Teniposide; Topotecan; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Vincristine

1999
Schedule-dependent activity of irinotecan plus BCNU against malignant glioma xenografts.
    Cancer chemotherapy and pharmacology, 2000, Volume: 45, Issue:4

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin; Carmustine; Drug Synergism; Drug Therapy, Combination; Female; Glioma; Humans; Irinotecan; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Transplantation, Heterologous

2000
Novel mutation of topoisomerase I in rendering cells resistant to camptothecin.
    Cancer research, 2002, Jul-01, Volume: 62, Issue:13

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Carboplatin; Carmustine; Catalysis; Cell Division; Cisplatin; DNA Damage; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Gene Expression; Humans; Nasopharyngeal Neoplasms; Point Mutation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Neoplasm; Tumor Cells, Cultured

2002
O6-benzylguanine-mediated enhancement of chemotherapy.
    Molecular cancer therapeutics, 2002, Volume: 1, Issue:11

    Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Camptothecin; Carmustine; Central Nervous System Neoplasms; Cyclophosphamide; Dacarbazine; DNA; Enzyme Inhibitors; Female; Guanine; Humans; Irinotecan; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Protein Synthesis Inhibitors; Temozolomide

2002
Camptothecin analogs in malignant gliomas: comparative analysis and characterization.
    Journal of neurosurgery, 2003, Volume: 98, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Camptothecin; Carmustine; Cell Division; Drug Screening Assays, Antitumor; Glioma; Humans; Rats; Tumor Cells, Cultured

2003
Potentiation of chemotherapeutic agents following antagonism of nuclear factor kappa B in human gliomas.
    Journal of neuro-oncology, 2003, Volume: 61, Issue:3

    Topics: Adenoviridae; Antineoplastic Agents; Apoptosis; Camptothecin; Carboplatin; Carmustine; Drug Synergism; Genetic Therapy; Glioma; Humans; I-kappa B Proteins; Irinotecan; NF-kappa B; NF-KappaB Inhibitor alpha; Repressor Proteins; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2003
Systemic BCNU enhances the efficacy of local delivery of a topoisomerase I inhibitor against malignant glioma.
    Cancer chemotherapy and pharmacology, 2004, Volume: 54, Issue:4

    Topics: Animals; Brain Neoplasms; Camptothecin; Carmustine; Cell Line, Tumor; Enzyme Inhibitors; Female; Gliosarcoma; Irinotecan; Neoplasm Transplantation; Rats; Rats, Inbred F344; Topoisomerase I Inhibitors

2004
In vitro drug response and molecular markers associated with drug resistance in malignant gliomas.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Aug-01, Volume: 12, Issue:15

    Topics: ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biomarkers, Tumor; Brain Neoplasms; Camptothecin; Carmustine; Cisplatin; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glioma; Glutathione S-Transferase pi; Humans; Immunohistochemistry; Irinotecan; Paclitaxel; Structure-Activity Relationship; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Vincristine

2006
Transcriptional repression of O6-methylguanine DNA methyltransferase gene rendering cells hypersensitive to N,N'-bis(2-chloroethyl)-N-nitrosurea in camptothecin-resistant cells.
    Molecular pharmacology, 2008, Volume: 74, Issue:2

    Topics: Camptothecin; Carmustine; Cell Line, Tumor; DNA Methylation; Down-Regulation; Drug Resistance, Neoplasm; Escherichia coli Proteins; Gene Expression Regulation, Enzymologic; Growth Inhibitors; HT29 Cells; Humans; KB Cells; O(6)-Methylguanine-DNA Methyltransferase; Transcription Factors

2008
[Retrospective analysis of 24 recurrent glioblastoma after chemoradiation and treated with nitrosoureas or irinotecan and bevacizumab].
    Bulletin du cancer, 2012, Feb-01, Volume: 99, Issue:2

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Camptothecin; Carmustine; Chemoradiotherapy; Chemotherapy, Adjuvant; Cohort Studies; Dacarbazine; Drug Therapy, Combination; Glioblastoma; Humans; Irinotecan; Lomustine; Middle Aged; Neoplasm Recurrence, Local; Nitrosourea Compounds; Radiation-Sensitizing Agents; Retrospective Studies; Temozolomide

2012
Concurrent delivery of carmustine, irinotecan, and cisplatin to the cerebral cavity using biodegradable nanofibers: In vitro and in vivo studies.
    Colloids and surfaces. B, Biointerfaces, 2015, Oct-01, Volume: 134

    Topics: Animals; Antineoplastic Agents; Brain; Brain Neoplasms; Camptothecin; Carmustine; Cisplatin; Glioblastoma; In Vitro Techniques; Irinotecan; Nanofibers; Rats; Rats, Wistar

2015