Page last updated: 2024-08-22

camptothecin and carbostyril

camptothecin has been researched along with carbostyril in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (9.09)18.2507
2000's5 (45.45)29.6817
2010's5 (45.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chu, DT; Clement, JJ; Permana, PA; Plattner, JJ; Shen, LL; Snapka, RM1
Beard, C; Bronson, R; Buhlmann, JE; Curry, R; Dausman, J; Guarente, L; Jaenisch, R; Johnson, B; Lipman, R; Lombard, DB; Marciniak, RA; Sharpe, A1
Heinemann, V1
Alpaugh, RK; Cohen, SJ; Gallo, J; Gentner, L; Lewis, NL; Meropol, NJ; Palmer, PA; Rogatko, A; Schol, J; Verhaeghe, T; Weiner, LM; Yeslow, G; Zannikos, P1
de Bruijn, P; de Heus, G; de Jonge, MJ; Eskens, FA; Kehrer, DF; Klaren, A; Mathijssen, RH; Palmer, PA; Planting, AS; Sparreboom, A; Verhaeghe, T; Verheij, C; Verweij, J; Xie, R; Zhang, S1
Borner, MM1
Leo, E; Marchand, C; Pommier, Y; Zhang, H1
Agama, K; An, LK; Du, J; Gu, LQ; Huang, ZS; Li, D; Pommier, Y; Wu, N; Wu, XW1
Peyroche, A; Tallec, BL1
Ban, LY; Fang, FQ; Guo, HS; Liu, JW; Yu, PY; Zhang, J1
Caron, NS; Deng, Y; Ehrnhoefer, DE; Hayden, MR; Qiu, X; Tsang, M1

Reviews

3 review(s) available for camptothecin and carbostyril

ArticleYear
Gemcitabine in the treatment of advanced pancreatic cancer: a comparative analysis of randomized trials.
    Seminars in oncology, 2002, Volume: 29, Issue:6 Suppl 20

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Camptothecin; Capecitabine; Cisplatin; Deoxycytidine; Docetaxel; Fluorouracil; Gemcitabine; Glutamates; Guanine; Humans; Hydroxamic Acids; Irinotecan; Organic Chemicals; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Pancreatic Neoplasms; Pemetrexed; Phenylbutyrates; Quinolones; Randomized Controlled Trials as Topic; Taxoids

2002
[Molecular targets in colon cancer].
    Therapeutische Umschau. Revue therapeutique, 2006, Volume: 63, Issue:4

    Topics: Angiogenesis Inhibitors; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Camptothecin; Cetuximab; Clinical Trials as Topic; Clinical Trials, Phase II as Topic; Colonic Neoplasms; Drug Delivery Systems; ErbB Receptors; Gefitinib; Humans; Imatinib Mesylate; Indoles; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Phthalazines; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Quinolones; Receptors, Platelet-Derived Growth Factor; Receptors, Somatomedin; Signal Transduction; Sirolimus; Sunitinib

2006
DNA topoisomerases and their poisoning by anticancer and antibacterial drugs.
    Chemistry & biology, 2010, May-28, Volume: 17, Issue:5

    Topics: Anti-Bacterial Agents; Antineoplastic Agents; Camptothecin; DNA Topoisomerases; Doxorubicin; Enzyme Inhibitors; Etoposide; Humans; Mitoxantrone; Quinolones; Topoisomerase Inhibitors

2010

Trials

2 trial(s) available for camptothecin and carbostyril

ArticleYear
Phase I and pharmacokinetic study of the farnesyltransferase inhibitor R115777 in combination with irinotecan in patients with advanced cancer.
    Cancer chemotherapy and pharmacology, 2004, Volume: 53, Issue:6

    Topics: Administration, Oral; Aged; Alkyl and Aryl Transferases; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Camptothecin; Diarrhea; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Farnesyltranstransferase; Female; Humans; Infusions, Intravenous; Irinotecan; Male; Middle Aged; Neoplasms; Quinolones

2004
Phase I and pharmacokinetic study of irinotecan in combination with R115777, a farnesyl protein transferase inhibitor.
    British journal of cancer, 2004, Apr-19, Volume: 90, Issue:8

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Female; Humans; Infusions, Intravenous; Irinotecan; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Quinolones; Treatment Outcome

2004

Other Studies

6 other study(ies) available for camptothecin and carbostyril

ArticleYear
Quinobenoxazines: a class of novel antitumor quinolones and potent mammalian DNA topoisomerase II catalytic inhibitors.
    Biochemistry, 1994, Sep-20, Volume: 33, Issue:37

    Topics: Animals; Antineoplastic Agents; Camptothecin; Cattle; Cell Line; Chlorocebus aethiops; DNA Replication; Doxorubicin; Kidney; Kinetics; Oxazines; Quinolones; Simian virus 40; Structure-Activity Relationship; Teniposide; Thymus Gland; Topoisomerase II Inhibitors

1994
Mutations in the WRN gene in mice accelerate mortality in a p53-null background.
    Molecular and cellular biology, 2000, Volume: 20, Issue:9

    Topics: 4-Nitroquinoline-1-oxide; Animals; Blotting, Western; Camptothecin; Cell Division; Cells, Cultured; Cellular Senescence; Cloning, Molecular; DNA Helicases; Dose-Response Relationship, Drug; Embryo, Mammalian; Exodeoxyribonucleases; Fibroblasts; Gene Library; Life Expectancy; Mice; Mice, Knockout; Molecular Sequence Data; Mutation; Phenotype; Quinolones; RecQ Helicases; Spleen; Time Factors; Tissue Distribution; Tumor Suppressor Protein p53; Werner Syndrome Helicase

2000
A novel DNA topoisomerase I inhibitor with different mechanism from camptothecin induces G2/M phase cell cycle arrest to K562 cells.
    Biochemistry, 2010, Nov-30, Volume: 49, Issue:47

    Topics: Camptothecin; Cell Division; Cell Proliferation; DNA Topoisomerases, Type I; Humans; Indolizines; K562 Cells; Quinolones; Topoisomerase I Inhibitors

2010
Using DNA damage sensitivity phenotypes to characterize mutations affecting proteasome function.
    Methods in molecular biology (Clifton, N.J.), 2012, Volume: 832

    Topics: 4-Nitroquinoline-1-oxide; Camptothecin; Canavanine; DNA Damage; Methyl Methanesulfonate; Mutation; Polyubiquitin; Proteasome Endopeptidase Complex; Quinolones; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2012
Anti-cancer effects of 2-oxoquinoline derivatives on the HCT116 and LoVo human colon cancer cell lines.
    Molecular medicine reports, 2015, Volume: 12, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Camptothecin; Caspase 3; Cell Line, Tumor; Colonic Neoplasms; Extracellular Signal-Regulated MAP Kinases; Fluorouracil; HCT116 Cells; Humans; Irinotecan; JNK Mitogen-Activated Protein Kinases; Myeloid Cell Leukemia Sequence 1 Protein; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Quinolones

2015
Laquinimod decreases Bax expression and reduces caspase-6 activation in neurons.
    Experimental neurology, 2016, Volume: 283, Issue:Pt A

    Topics: Animals; Antineoplastic Agents, Phytogenic; bcl-2-Associated X Protein; Camptothecin; Caspase 6; Cerebral Cortex; COS Cells; Disease Models, Animal; Dose-Response Relationship, Drug; Down Syndrome; Gene Expression Regulation; Humans; Huntingtin Protein; Mice; Mice, Transgenic; Mutation; Neurons; Protein Synthesis Inhibitors; Quinolones; Time Factors; Tosylphenylalanyl Chloromethyl Ketone

2016