camptothecin has been researched along with buthionine sulfoximine in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Bonner, JA; Sawyer, TE | 1 |
| Akiyama, SI; Chen, ZS; Furukawa, T; Ono, K; Seto, K; Sumizawa, T; Ueda, K | 1 |
| Aller, P; de Blas, E; Fernández, C; Sancho, P; Troyano, A | 1 |
| Kumazaki, T; Nishiyama, M; Okamoto, R; Sekikawa, T; Takano, H; Tanaka, T; Tanimoto, K; Toyada, M; Ukon, K | 1 |
| Adams, DJ; Colvin, OM; Flowers, JL; Gamcsik, MP; Kasibhatla, MS; Kohlhagen, G; Manikumar, G; Pommier, Y; Wall, ME; Wani, M | 1 |
| Inoue, H; Miyashita, T; Takemura, H; Ueda, T; Yoshida, A | 1 |
| Doneanu, CE; Niture, SK; Pattabiraman, N; Srivenugopal, KS; Velu, CS | 1 |
| Alonso-Varona, A; Caramés, M; García-Alonso, I; Palomares, T | 1 |
| Gordon, N; Hollomon, MG; Kleinerman, ES; Santiago-O'Farrill, JM | 1 |
| Gutiérrez-Kobeh, L; Rodríguez-González, J; Wilkins-Rodríguez, AA | 1 |
12 other study(ies) available for camptothecin and buthionine sulfoximine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
The interaction of buthionine sulphoximide (BSO) and the topoisomerase I inhibitor CPT-11.
Topics: Animals; Antineoplastic Agents, Phytogenic; Buthionine Sulfoximine; Camptothecin; Cell Survival; Cells, Cultured; Cricetinae; Drug Interactions; Enzyme Inhibitors; Glutathione; Irinotecan; Topoisomerase I Inhibitors | 1996 |
ATP-Dependent efflux of CPT-11 and SN-38 by the multidrug resistance protein (MRP) and its inhibition by PAK-104P.
Topics: Adenosine Triphosphate; Anion Transport Proteins; Antineoplastic Agents, Phytogenic; ATP-Binding Cassette Transporters; Biological Transport; Buthionine Sulfoximine; Camptothecin; Carrier Proteins; Cell Line; Cell Survival; Culture Media; Cyclic P-Oxides; DNA Topoisomerases, Type I; Drug Resistance, Multiple; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Irinotecan; Isoenzymes; KB Cells; Multidrug Resistance-Associated Proteins; Nicotinic Acids; Propionates; Quinolines | 1999 |
Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U-937 human promonocytic cells. The role of intracellular oxidation.
Topics: Adenosine Triphosphate; Alkylating Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Buthionine Sulfoximine; Camptothecin; Cell Death; Cisplatin; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Doxorubicin; Enzyme Inhibitors; Etoposide; Flow Cytometry; Glutathione; Humans; Hydrogen Peroxide; Hypoxia; Immunoblotting; Melphalan; Membrane Potentials; Mitochondria; Monocytes; Necrosis; Nucleic Acid Synthesis Inhibitors; Oxygen; Radiation-Protective Agents; Reactive Oxygen Species; Spectrometry, Fluorescence; Time Factors; Topoisomerase I Inhibitors; U937 Cells | 2001 |
Unique action determinants of double acting topoisomerase inhibitor, TAS-103.
Topics: Aminoquinolines; Antineoplastic Agents, Phytogenic; Blotting, Northern; Blotting, Western; Buthionine Sulfoximine; Camptothecin; Drug Resistance; Enzyme Inhibitors; Etoposide; Fungal Proteins; Glutamate-Cysteine Ligase; Glutathione; GTP-Binding Proteins; Humans; Indenes; Irinotecan; Mitochondrial Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured | 2001 |
Dual role of glutathione in modulating camptothecin activity: depletion potentiates activity, but conjugation enhances the stability of the topoisomerase I-DNA cleavage complex.
Topics: Antineoplastic Agents, Phytogenic; Buthionine Sulfoximine; Camptothecin; Chromatography, High Pressure Liquid; DNA Topoisomerases, Type I; DNA, Neoplasm; Drug Synergism; Female; Glutathione; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Structure-Activity Relationship; Tumor Cells, Cultured | 2001 |
Inhibition of glutathione synthesis overcomes Bcl-2-mediated topoisomerase inhibitor resistance and induces nonapoptotic cell death via mitochondrial-independent pathway.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Buthionine Sulfoximine; Camptothecin; Caspase 3; Caspase 7; Caspases; Cell Death; Cell Line, Tumor; DNA Topoisomerases, Type I; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Activation; Etoposide; Gene Expression Regulation, Leukemic; Glutathione; Humans; Irinotecan; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Topoisomerase I Inhibitors; Tumor Suppressor Protein p53 | 2006 |
Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress.
Topics: Acetylcysteine; Amino Acid Sequence; Binding Sites; Buthionine Sulfoximine; Camptothecin; Cell Line, Tumor; Cross-Linking Reagents; Cysteine; Diamide; DNA Damage; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Glutaral; Glutathione; Glutathione Disulfide; Humans; Hydrogen Peroxide; Models, Molecular; Oxidative Stress; Phosphorylation; Recombinant Proteins; Tandem Mass Spectrometry; tert-Butylhydroperoxide; Tumor Suppressor Protein p53 | 2007 |
Glutathione modulators reverse the pro-tumour effect of growth factors enhancing WiDr cell response to chemotherapeutic agents.
Topics: Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Camptothecin; Cell Growth Processes; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Epidermal Growth Factor; Fluorouracil; Glutathione; Hepatocyte Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Pyrrolidonecarboxylic Acid; Thiazolidines; Vascular Endothelial Growth Factor A | 2010 |
Knockdown of autophagy-related protein 5, ATG5, decreases oxidative stress and has an opposing effect on camptothecin-induced cytotoxicity in osteosarcoma cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Autophagy; Autophagy-Related Protein 5; Bone Neoplasms; Buthionine Sulfoximine; Camptothecin; Caspases; Cell Line, Tumor; Cell Survival; Enzyme Activation; Gene Knockdown Techniques; Membrane Potential, Mitochondrial; Mice; Microtubule-Associated Proteins; Osteosarcoma; Oxidative Stress | 2013 |
Role of glutathione, ROS, and Bcl-xL in the inhibition of apoptosis of monocyte-derived dendritic cells by Leishmania mexicana promastigotes.
Topics: Animals; Apoptosis; bcl-X Protein; Buthionine Sulfoximine; Camptothecin; Cells, Cultured; Dendritic Cells; Down-Regulation; Glutathione; Humans; Leishmania mexicana; Phosphorylation; Reactive Oxygen Species | 2018 |