Compounds > camptothecin
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camptothecin and bromodeoxyuridine

camptothecin has been researched along with bromodeoxyuridine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (35.00)18.2507
2000's11 (55.00)29.6817
2010's2 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Oikawa, A; Tohda, H; Zhao, JH1
Epe, B; Hoehn, H; Poot, M1
Nagao, M; Oikawa, A; Sugimura, T; Tohda, H1
Darzynkiewicz, Z; Li, X; Traganos, F1
Darzynkiewicz, Z; Li, X; Melamed, MR1
Darzynkiewicz, Z; James, WM; Li, X; Traganos, F1
Falcieri, E; Falconi, M; Gobbi, P; Marhefka, G; Santi, S; Vitale, M; Zamai, L1
Darzynkiewicz, Z; Juan, G; Traganos, F1
Jaks, V; Jõers, A; Kristjuhan, A; Maimets, T1
Daoud, SS; Meadows, GG; Redkar, AA1
Balan, KV; Calabresi, P; Darnowski, JW; Dunaway, S; Han, Z; Hendrickson, EA; Pantazis, P; Sedivy, J; Wei, W; Wyche, JH1
Poot, M; Rabinovitch, PS; Silber, JR1
Aguirre, A; Diáz-González, F; Dorta, J; Fernández, JJ; Moser-Thier, K; Pec, MK; Souto, ML; Villar, J1
Kawada, K; Kawano, T; Miyake, S; Nagai, K; Nakajima, Y; Nishikage, T; Ogiya, K; Tanaka, K; Toukairin, Y1
Abraham, RT; Chiang, GG; Liu, YC; Mercurio, F; Otterness, DM; Xie, W; Zhang, YW1
Braun, T; Carvalho, G; Castedo, M; Coquelle, A; Kroemer, G; Métivier, D; Mouhamad, S; Pequignot, MO; Vivet, S1
Ayusawa, D; Endoh, M; Fuji, M; Hossain, MN; Miki, K1
Emond, MJ; Lauper, JM; Mao, FJ; Monnat, RJ; Sidorova, JM1
Bussom, S; Cheng, YC; Guan, F; Gullen, EA; Jiang, Z; Lam, W; Liu, SH; Zhang, W1

Other Studies

20 other study(ies) available for camptothecin and bromodeoxyuridine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Camptothecin-induced sister-chromatid exchange dependent on the presence of bromodeoxyuridine and the phase of the cell cycle.
    Mutation research, 1992, Volume: 282, Issue:1

    Topics: Bromodeoxyuridine; Camptothecin; Cell Cycle; Cells, Cultured; Drug Interactions; Humans; Mutagens; Sister Chromatid Exchange

1992
Cell cycle effects of the DNA topoisomerase inhibitors camptothecin and m-AMSA in lymphoblastoid cell lines from patients with Fanconi anemia.
    Mutation research, 1992, Nov-16, Volume: 270, Issue:2

    Topics: Amsacrine; Bromodeoxyuridine; Camptothecin; Cell Line; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Fanconi Anemia; Flow Cytometry; G2 Phase; Humans; Lymphocytes; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1992
Okadaic acid, a protein phosphatase inhibitor, induces sister-chromatid exchanges depending on the presence of bromodeoxyuridine.
    Mutation research, 1993, Volume: 289, Issue:2

    Topics: Animals; Benzamides; Bromodeoxyuridine; Camptothecin; Cell Line; CHO Cells; Cricetinae; Cricetulus; DNA Replication; DNA Topoisomerases, Type I; Drug Synergism; Enzyme Activation; Ethers, Cyclic; Humans; Lymphocytes; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Phosphatase 1; Sister Chromatid Exchange

1993
Simultaneous analysis of DNA replication and apoptosis during treatment of HL-60 cells with camptothecin and hyperthermia and mitogen stimulation of human lymphocytes.
    Cancer research, 1994, Aug-15, Volume: 54, Issue:16

    Topics: Apoptosis; Bromodeoxyuridine; Camptothecin; DNA Replication; DNA, Neoplasm; Humans; Hyperthermia, Induced; Idoxuridine; Leukemia, Promyelocytic, Acute; Lymphocyte Activation; Tumor Cells, Cultured

1994
Detection of apoptosis and DNA replication by differential labeling of DNA strand breaks with fluorochromes of different color.
    Experimental cell research, 1996, Jan-10, Volume: 222, Issue:1

    Topics: Antibodies, Monoclonal; Apoptosis; Bromodeoxyuridine; Camptothecin; Cold Temperature; Cytophotometry; Deoxycytosine Nucleotides; DNA; DNA Replication; Enzyme Inhibitors; Flow Cytometry; Fluorescent Dyes; HL-60 Cells; Humans; Lasers; Photolysis; Proliferating Cell Nuclear Antigen; Topoisomerase I Inhibitors; Tumor Cells, Cultured; Uridine Triphosphate

1996
Application of biotin, digoxigenin or fluorescein conjugated deoxynucleotides to label DNA strand breaks for analysis of cell proliferation and apoptosis using flow cytometry.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 1995, Volume: 70, Issue:5

    Topics: Apoptosis; Biotin; Bone Marrow; Bromodeoxyuridine; Camptothecin; Cell Division; Deoxyuracil Nucleotides; Digoxigenin; DNA; DNA Nucleotidylexotransferase; DNA Probes; Flow Cytometry; Fluoresceins; HL-60 Cells; Humans; Immunohistochemistry; Indicators and Reagents; Reagent Kits, Diagnostic

1995
Anti-BrdUrd labeling of newly synthesized DNA in HL-60 cells triggered to apoptosis.
    Cytometry, 1996, Dec-01, Volume: 25, Issue:4

    Topics: Antibodies, Monoclonal; Aphidicolin; Apoptosis; Bromodeoxyuridine; Camptothecin; DNA, Neoplasm; HL-60 Cells; Humans; Time Factors; Topoisomerase I Inhibitors

1996
Cell-cycle analysis of drug-treated cells.
    Methods in molecular biology (Clifton, N.J.), 2001, Volume: 95

    Topics: Acids; Amsacrine; Antineoplastic Agents; Bromodeoxyuridine; Camptothecin; Cell Cycle; Cyclins; DNA; Flow Cytometry; Fluorescent Dyes; HL-60 Cells; Hot Temperature; Humans; Immunohistochemistry; Nucleic Acid Denaturation; Topoisomerase I Inhibitors

2001
p53 protein accumulation in addition to the transactivation activity is required for p53-dependent cell cycle arrest after treatment of cells with camptothecin.
    Oncogene, 2001, Mar-08, Volume: 20, Issue:10

    Topics: 3T3 Cells; Animals; Antineoplastic Agents; Blotting, Western; Bromodeoxyuridine; Camptothecin; Cell Cycle; Cyclin G; Cyclin G1; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Damage; DNA Primers; DNA Replication; DNA-Directed RNA Polymerases; G1 Phase; Humans; Mice; Polymerase Chain Reaction; S Phase; Trans-Activators; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Viral Proteins

2001
UCN-01 dose-dependent inhibition of normal hyperproliferative cells in mice.
    International journal of oncology, 2001, Volume: 19, Issue:1

    Topics: Alkaloids; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Bone Marrow; Bone Marrow Cells; Bromodeoxyuridine; Camptothecin; Cell Division; Colony-Forming Units Assay; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Humans; Immunoenzyme Techniques; Intestinal Mucosa; Male; Mice; Mice, Inbred C57BL; Protein Kinase C; Staurosporine; Topoisomerase I Inhibitors; Topotecan

2001
Role of p21 in apoptosis and senescence of human colon cancer cells treated with camptothecin.
    The Journal of biological chemistry, 2002, May-10, Volume: 277, Issue:19

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; beta-Galactosidase; Blotting, Western; Bromodeoxyuridine; Camptothecin; Cell Cycle; Cellular Senescence; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA Damage; Dose-Response Relationship, Drug; Down-Regulation; Humans; Microscopy, Fluorescence; Models, Biological; Protein Binding; Time Factors; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2002
A novel flow cytometric technique for drug cytotoxicity gives results comparable to colony-forming assays.
    Cytometry, 2002, May-01, Volume: 48, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Antimetabolites; Antineoplastic Agents, Phytogenic; Benzimidazoles; Bromodeoxyuridine; Camptothecin; Carcinogens; Cell Division; Cell Line; Cell Survival; Fibroblasts; Flow Cytometry; Fluorescent Dyes; Humans; Lymphocytes; Stem Cells; Werner Syndrome

2002
Induction of apoptosis in estrogen dependent and independent breast cancer cells by the marine terpenoid dehydrothyrsiferol.
    Biochemical pharmacology, 2003, May-01, Volume: 65, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Bromodeoxyuridine; Camptothecin; Cell Cycle; Cell Division; Colchicine; DNA; Doxorubicin; Estrogens; Humans; Phosphatidylserines; Pyrans; Tumor Cells, Cultured

2003
The expressions of p21 and pRB may be good indicators for the sensitivity of esophageal squamous cell cancers to CPT-11: Cell proliferation activity correlates with the effect of CPT-11.
    Cancer science, 2004, Volume: 95, Issue:5

    Topics: Adenovirus E1A Proteins; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Bromodeoxyuridine; Camptothecin; Carcinoma, Squamous Cell; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cell Division; DNA Topoisomerases, Type I; Enzyme-Linked Immunosorbent Assay; Esophageal Neoplasms; Gene Expression Profiling; Humans; Immunohistochemistry; Irinotecan; Nuclear Proteins; Proto-Oncogene Proteins p21(ras); Repressor Proteins; Tumor Cells, Cultured

2004
Genotoxic stress targets human Chk1 for degradation by the ubiquitin-proteasome pathway.
    Molecular cell, 2005, Sep-02, Volume: 19, Issue:5

    Topics: Bromodeoxyuridine; Camptothecin; Cell Cycle Proteins; Cell Line; Cell Line, Tumor; Checkpoint Kinase 1; Cullin Proteins; DNA Damage; Down-Regulation; Genes, Reporter; Humans; Proteasome Endopeptidase Complex; Protein Kinases; S Phase; Ubiquitin

2005
Enrichment of non-synchronized cells in the G1, S and G2 phases of the cell cycle for the study of apoptosis.
    Biochemical pharmacology, 2006, Nov-30, Volume: 72, Issue:11

    Topics: Apoptosis; Bromodeoxyuridine; Camptothecin; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Fluorescent Antibody Technique; Humans; Interphase; Nitriles; Ploidies; Staurosporine; Sulfones

2006
Downregulation of hnRNP C1/C2 by siRNA sensitizes HeLa cells to various stresses.
    Molecular and cellular biochemistry, 2007, Volume: 296, Issue:1-2

    Topics: Antimetabolites; Antineoplastic Agents; Bromodeoxyuridine; Camptothecin; Diketopiperazines; Enzyme Inhibitors; Gene Expression Regulation; HeLa Cells; Herbicides; Heterogeneous-Nuclear Ribonucleoprotein Group C; Humans; Hydrogen Peroxide; Oxidants; Paraquat; Piperazines; RNA, Small Interfering

2007
The human WRN and BLM RecQ helicases differentially regulate cell proliferation and survival after chemotherapeutic DNA damage.
    Cancer research, 2010, Aug-15, Volume: 70, Issue:16

    Topics: Antineoplastic Agents; Bone Neoplasms; Bromodeoxyuridine; Camptothecin; Cell Growth Processes; Cell Line, Tumor; Cisplatin; DNA Damage; Exodeoxyribonucleases; Fibroblasts; Fluorouracil; Histones; Humans; Hydroxyurea; Osteosarcoma; RecQ Helicases; Werner Syndrome Helicase

2010
The four-herb Chinese medicine PHY906 reduces chemotherapy-induced gastrointestinal toxicity.
    Science translational medicine, 2010, Aug-18, Volume: 2, Issue:45

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; beta Catenin; Biomarkers, Tumor; Bromodeoxyuridine; Camptothecin; Cell Proliferation; DNA Damage; Drugs, Chinese Herbal; Gastrointestinal Tract; Glucuronidase; Humans; Inflammation; Irinotecan; Medicine, Chinese Traditional; Mice; Proliferating Cell Nuclear Antigen; Recovery of Function; Signal Transduction; Stem Cells; Transplantation, Homologous; Weight Loss; Wnt Proteins; Wnt3 Protein; Wnt3A Protein

2010