Page last updated: 2024-08-22

camptothecin and bisbenzimidazole

camptothecin has been researched along with bisbenzimidazole in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's4 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (12.50)2.80

Authors

AuthorsStudies
Beerman, TA; McHugh, MM; Sigmund, RD1
Heimpel, S; Hiller, KH; Hoehn, H; Poot, M1
Kinzler, KW; Lengauer, C; Vogelstein, B; Waldman, T1
Saravia, NG; Walker, J1
Barthelmes, HU; Boege, F; Christensen, MO; Fritz, J; Habermeyer, M; Larsen, MK; Marko, D1
Coombs, GH; Goyeneche, D; Jean-Moreno, V; Rojas, R; Walker, J1
Khan, QA; Pilch, DS1
Capek, J; Handl, J; Majtnerova, P; Petira, F; Rousar, T1

Other Studies

8 other study(ies) available for camptothecin and bisbenzimidazole

ArticleYear
Effects of minor groove binding drugs on camptothecin-induced DNA lesions in L1210 nuclei.
    Biochemical pharmacology, 1990, Feb-15, Volume: 39, Issue:4

    Topics: Animals; Benzimidazoles; Bisbenzimidazole; Camptothecin; Cell Nucleus; Distamycins; DNA Damage; DNA Repair; DNA, Neoplasm; Drug Interactions; Indoles; Leukemia L1210; Molecular Structure; Pyrroles; Topoisomerase I Inhibitors

1990
Distinct patterns of cell cycle disturbance elicited by compounds interfering with DNA topoisomerase I and II activity.
    Experimental cell research, 1995, Volume: 218, Issue:1

    Topics: Amsacrine; Bisbenzimidazole; Camptothecin; Cell Cycle; Cell Line; Distamycins; DNA; Dose-Response Relationship, Drug; Ethidium; Flow Cytometry; Humans; Intercalating Agents; Kinetics; Lymphocytes; Netropsin; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1995
Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21.
    Nature, 1996, Jun-20, Volume: 381, Issue:6584

    Topics: Antineoplastic Agents; Apoptosis; Bisbenzimidazole; Camptothecin; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; DNA Damage; Doxorubicin; Enzyme Inhibitors; Etoposide; Fluorescent Dyes; Gamma Rays; Humans; Mitosis; S Phase; Tumor Cells, Cultured

1996
Inhibition of Leishmania donovani promastigote DNA topoisomerase I and human monocyte DNA topoisomerases I and II by antimonial drugs and classical antitopoisomerase agents.
    The Journal of parasitology, 2004, Volume: 90, Issue:5

    Topics: Animals; Antimony; Antimony Potassium Tartrate; Antimony Sodium Gluconate; Antiprotozoal Agents; Benzimidazoles; Bisbenzimidazole; Camptothecin; Cell Survival; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Leishmania donovani; Meglumine; Meglumine Antimoniate; Monocytes; Organometallic Compounds; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; U937 Cells

2004
Anthocyanidins modulate the activity of human DNA topoisomerases I and II and affect cellular DNA integrity.
    Chemical research in toxicology, 2005, Volume: 18, Issue:9

    Topics: Anthocyanins; Bisbenzimidazole; Camptothecin; Catalysis; Cell Line; Comet Assay; DNA; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Enzyme Inhibitors; Ethidium; Humans; Molecular Structure; Recombinant Proteins; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

2005
Leishmania donovani: differential activities of classical topoisomerase inhibitors and antileishmanials against parasite and host cells at the level of DNA topoisomerase I and in cytotoxicity assays.
    Experimental parasitology, 2006, Volume: 112, Issue:1

    Topics: Acid Phosphatase; Animals; Antimony Sodium Gluconate; Antiprotozoal Agents; Benzimidazoles; Berberine Alkaloids; Bisbenzimidazole; Camptothecin; Cell Line; Diminazene; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Leishmania donovani; Luciferases, Firefly; Luminescent Agents; Macrophages; Monocytes; Pentamidine; Quercetin; Topoisomerase I Inhibitors

2006
Topoisomerase I-mediated DNA cleavage induced by the minor groove-directed binding of bibenzimidazoles to a distal site.
    Journal of molecular biology, 2007, Jan-19, Volume: 365, Issue:3

    Topics: Base Pairing; Base Sequence; Benzimidazoles; Binding Sites; Bisbenzimidazole; Camptothecin; Deoxyribonuclease I; DNA; DNA Cleavage; DNA Footprinting; DNA Topoisomerases, Type I; Fluorescence; Humans; Indoles; Ligands; Molecular Sequence Data; Nucleic Acid Conformation; Poly dA-dT; Temperature

2007
Quantitative spectrofluorometric assay detecting nuclear condensation and fragmentation in intact cells.
    Scientific reports, 2021, 06-07, Volume: 11, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Bisbenzimidazole; Camptothecin; Cell Death; Cell Line; Cell Nucleus; Cisplatin; DNA Fragmentation; Flow Cytometry; Hep G2 Cells; Humans; Microscopy, Fluorescence; Reproducibility of Results; Spectrometry, Fluorescence; Staurosporine

2021