Page last updated: 2024-08-22

camptothecin and biotin

camptothecin has been researched along with biotin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (22.22)18.2507
2000's4 (22.22)29.6817
2010's7 (38.89)24.3611
2020's3 (16.67)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Cao, SL; Jiang, W; Li, J; Li, YS; Li, Z; Liao, J; Peng, B; Ren, TT; Wang, FC; Wang, G; Wang, H; Xu, S; Xu, X; Yang, CR1
Darzynkiewicz, Z; James, WM; Li, X; Traganos, F1
Lerner, CG; Saiki, AY1
Basi, GS; Earnshaw, WC; Eischen, CM; Kaufmann, SH; Kottke, TJ; Leibson, PJ; Martins, LM; Tung, JS1
Joshi, B; Li, L; Tang, DG; Zhu, Z1
Enomoto, T; Kobayashi, T; Murofushi, H; Seki, M; Tada, S; Tsuyama, T1
Amessou, M; Decaudin, D; El Alaoui, A; Florent, JC; Johannes, L; Sarr, M; Schmidt, F1
Kobayashi, S; Kuramochi, K; Sakaguchi, K; Sugawara, F; Takakusagi, K; Takakusagi, Y1
Caruthers, SD; Gaffney, PJ; Hu, G; Lanza, GM; Pan, D; Scott, MJ; Senpan, A; Wickline, SA1
Chen, YJ; Kamath, A; Ojima, I; Seitz, JD; Vineberg, JG; Zuniga, ES1
Liu, Z; Xiong, X; Yan, B; Yang, A; Zhou, M1
Amini, M; Atyabi, F; Baharian, A; Dinarvand, R; Ghahremani, MH; Gharghabi, M; Mehdizadeh, M; Ostad, SN; Rouhani, H; Sepehri, N; Varshochian, R1
Cincinelli, R; Dallavalle, S; De Santis, R; Giannini, G; Minenkova, O; Musso, L; Santapaola, D; Vesci, L1
Ding, R; Li, Z; Wang, J; Wang, M; Zhao, Z; Zhu, X1
Dhiman, S; Kaur, A; Lee, HB; Sharma, M1
Motohashi, Y; Nishihara, T; Tanabe, K1
Chen, Y; Dai, Y; Ye, T; Zhang, Y1

Other Studies

18 other study(ies) available for camptothecin and biotin

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Synthesis, cytotoxic evaluation and target identification of thieno[2,3-d]pyrimidine derivatives with a dithiocarbamate side chain at C2 position.
    European journal of medicinal chemistry, 2018, Jun-25, Volume: 154

    Topics: Antineoplastic Agents; Cell Cycle; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pyrimidines; Structure-Activity Relationship; Thiocarbamates; Tumor Cells, Cultured

2018
Application of biotin, digoxigenin or fluorescein conjugated deoxynucleotides to label DNA strand breaks for analysis of cell proliferation and apoptosis using flow cytometry.
    Biotechnic & histochemistry : official publication of the Biological Stain Commission, 1995, Volume: 70, Issue:5

    Topics: Apoptosis; Biotin; Bone Marrow; Bromodeoxyuridine; Camptothecin; Cell Division; Deoxyuracil Nucleotides; Digoxigenin; DNA; DNA Nucleotidylexotransferase; DNA Probes; Flow Cytometry; Fluoresceins; HL-60 Cells; Humans; Immunohistochemistry; Indicators and Reagents; Reagent Kits, Diagnostic

1995
Scintillation proximity assay for human DNA topoisomerase I using recombinant biotinyl-fusion protein produced in baculovirus-infected insect cells.
    Analytical biochemistry, 1996, Sep-05, Volume: 240, Issue:2

    Topics: Animals; Bacterial Proteins; Baculoviridae; Biotin; Camptothecin; Cells, Cultured; DNA; DNA Topoisomerases, Type I; Genetic Vectors; Humans; Plasmids; Recombinant Fusion Proteins; Scintillation Counting; Spodoptera; Streptavidin; Tritium

1996
Comparison of apoptosis in wild-type and Fas-resistant cells: chemotherapy-induced apoptosis is not dependent on Fas/Fas ligand interactions.
    Blood, 1997, Aug-01, Volume: 90, Issue:3

    Topics: Affinity Labels; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Biotin; Camptothecin; Caspase 3; Caspase 7; Caspases; Cisplatin; Cysteine Endopeptidases; Doxorubicin; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Fas Ligand Protein; fas Receptor; Flow Cytometry; Humans; Lamin Type B; Lamins; Leukemia-Lymphoma, Adult T-Cell; Membrane Glycoproteins; Methotrexate; Neoplasm Proteins; Nuclear Proteins; Oligopeptides; Poly(ADP-ribose) Polymerases; Staurosporine; Topoisomerase II Inhibitors; Topotecan; Tumor Cells, Cultured

1997
Apoptosis in the absence of cytochrome c accumulation in the cytosol.
    Biochemical and biophysical research communications, 1998, Jan-14, Volume: 242, Issue:2

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Biotin; Bleomycin; Blotting, Western; Camptothecin; Cytochrome c Group; Cytosol; Enzyme Inhibitors; Etoposide; Humans; Hydroxamic Acids; Lymphoma; Microscopy, Fluorescence; Mitochondria; Phalloidine; Poly(ADP-ribose) Polymerases; Staurosporine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vinblastine

1998
Focus-formation of replication protein A, activation of checkpoint system and DNA repair synthesis induced by DNA double-strand breaks in Xenopus egg extract.
    Journal of cell science, 2002, Aug-01, Volume: 115, Issue:Pt 15

    Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Biotin; Caffeine; Camptothecin; Cell Cycle Proteins; Cell Extracts; Cell Nucleus; Cell-Free System; Deoxyuracil Nucleotides; DNA Damage; DNA Repair; DNA-Binding Proteins; Eukaryotic Cells; Female; Geminin; Genes, cdc; Male; Oocytes; Protein Serine-Threonine Kinases; Replication Protein A; Site-Specific DNA-Methyltransferase (Adenine-Specific); Spermatozoa; Tumor Suppressor Proteins; Xenopus laevis; Xenopus Proteins

2002
Shiga toxin-mediated retrograde delivery of a topoisomerase I inhibitor prodrug.
    Angewandte Chemie (International ed. in English), 2007, Volume: 46, Issue:34

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biotin; Camptothecin; CHO Cells; Cricetinae; Cricetulus; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; HT29 Cells; Humans; Irinotecan; Prodrugs; Shiga Toxin; Shiga Toxins; Topoisomerase II Inhibitors; Trihexosylceramides

2007
Identification of C10 biotinylated camptothecin (CPT-10-B) binding peptides using T7 phage display screen on a QCM device.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Amino Acid Sequence; Antineoplastic Agents; Bacteriophage T7; Biosensing Techniques; Biotin; Biotinylation; Camptothecin; Humans; Molecular Conformation; Molecular Sequence Data; Peptide Library; Peptides; Protein Binding

2007
Ligand-directed nanobialys as theranostic agent for drug delivery and manganese-based magnetic resonance imaging of vascular targets.
    Journal of the American Chemical Society, 2008, Jul-23, Volume: 130, Issue:29

    Topics: Biotin; Camptothecin; Doxorubicin; Drug Delivery Systems; Fibrin; Humans; Magnetic Resonance Angiography; Manganese; Micelles; Microscopy, Atomic Force; Nanoparticles; Organometallic Compounds

2008
Design, synthesis, and biological evaluations of tumor-targeting dual-warhead conjugates for a taxoid-camptothecin combination chemotherapy.
    Journal of medicinal chemistry, 2014, Jul-10, Volume: 57, Issue:13

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biotin; Breast Neoplasms; Camptothecin; Cell Line, Tumor; Click Chemistry; Female; Glutathione; Humans; Inhibitory Concentration 50; Mice; Microscopy, Confocal; Microscopy, Fluorescence; Molecular Targeted Therapy; Receptors, Growth Factor; Taxoids

2014
Preparation of camptothecin-loaded targeting nanoparticles and their antitumor effects on hepatocellular carcinoma cell line H22.
    Drug delivery, 2016, Volume: 23, Issue:5

    Topics: Antineoplastic Agents; Biotin; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Humans; Nanoparticles; Polymers; Solubility; Tissue Distribution; Xenograft Model Antitumor Assays

2016
Biotin decorated PLGA nanoparticles containing SN-38 designed for cancer therapy.
    Artificial cells, nanomedicine, and biotechnology, 2017, Volume: 45, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Biological Transport; Biotin; Camptothecin; Cell Survival; Drug Carriers; Drug Compounding; Drug Liberation; Female; Humans; Hydrogen-Ion Concentration; Irinotecan; Kinetics; Lactic Acid; MCF-7 Cells; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer

2017
Growth inhibition of human ovarian carcinoma by a novel AvidinOX-anchored biotinylated camptothecin derivative.
    Bioorganic & medicinal chemistry letters, 2018, 11-01, Volume: 28, Issue:20

    Topics: Animals; Antineoplastic Agents; Avidin; Biotin; Camptothecin; Carcinoma; Cell Line, Tumor; Cell Proliferation; Female; Humans; Mice; Ovarian Neoplasms; Protein Binding

2018
Design and Synthesis of Galactose-Biotin Lipid Materials for Liposomes to Promote the Hepatoma Cell-Targeting Effect.
    Journal of pharmaceutical sciences, 2019, Volume: 108, Issue:9

    Topics: Antineoplastic Agents; Asialoglycoprotein Receptor; Biotin; Camptothecin; Carcinoma, Hepatocellular; Drug Carriers; Drug Liberation; Drug Screening Assays, Antitumor; Galactose; Hep G2 Cells; Hepatocytes; Humans; Lipids; Liposomes; Liver Neoplasms; Particle Size

2019
Synthesis and Antitumor Evaluation of Glutathione Responsive Self-Immolative Disulphide Linked Camptothecin-Biotin Conjugate.
    Anti-cancer agents in medicinal chemistry, 2022, Volume: 22, Issue:18

    Topics: Animals; Antineoplastic Agents; Biotin; Camptothecin; Disulfides; Glutathione; Rats; Rats, Wistar

2022
Preparation of a multifunctional photoactivated prodrug on a streptavidin scaffold bearing a DNA aptamer.
    Bioorganic & medicinal chemistry letters, 2022, 09-01, Volume: 71

    Topics: Antineoplastic Agents; Aptamers, Nucleotide; Biotin; Camptothecin; Epithelial Cell Adhesion Molecule; Prodrugs; Streptavidin

2022
Synthesis and Antitumor Evaluation of Biotin-SN38-Valproic Acid Conjugates.
    Molecules (Basel, Switzerland), 2023, May-07, Volume: 28, Issue:9

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biotin; Camptothecin; Cell Line, Tumor; Fibroblasts; HeLa Cells; Humans; Irinotecan; Mice; NIH 3T3 Cells; Valproic Acid

2023