Page last updated: 2024-08-22

camptothecin and bilirubin

camptothecin has been researched along with bilirubin in 39 studies

Research

Studies (39)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (7.69)	18.2507
2000's	26 (66.67)	29.6817
2010's	10 (25.64)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cvitkovic, E; Goldwasser, F; Lokiec, F; Mahjoubi, M; Misset, JL; Myara, A; Trivin, F; Wasserman, E	1
Coffman, BL; Green, MD; Iyer, L; King, CD; Ratain, MJ; Roy, SK; Tephly, TR; Whitington, PF	1
Das, S; Di Rienzo, A; Hall, D; Iyer, L; Kim, S; Mortell, MA; Ramírez, J; Ratain, MJ	1
Ando, Y; Hasegawa, Y; Ichiki, M; Shimokata, K; Sugiyama, T; Ueoka, H	1
Armand, JP; Boige, V; Ducreux, M; Faivre, S; Gatineau, M; Jacques, C; Raymond, E; Rixe, O; Sanderink, GJ; Vernillet, L	1
Cheng, C; Das, S; Di Rienzo, A; Grimsley, C; Innocenti, F; Kuttab-Boulos, H; Ramírez, J; Ratain, MJ	1
Atherton, PJ; Gupta, E; Kastrissios, H; Klein, CE; Pitot, HC; Ratain, MJ; Reid, JM; Sloan, JA	1
Fuchs, CS; Harker, G; Hecht, JR; Moore, MR; Rinaldi, D; Villa, L	1
Chen, PX; Das, S; Innocenti, F; Iyer, L; Janisch, L; Karrison, T; Kocherginsky, M; Ramírez, J; Ratain, MJ; Rudin, CM; Undevia, SD; Vokes, EE	1
Fuchs, CS; Kwok, A; McGovren, JP; Meyerhardt, JA; Ratain, MJ	1
Hasegawa, R; Jinno, H; Kamakura, S; Kamatani, N; Kaniwa, N; Katori, N; Kitakaze, M; Kitamura, Y; Komamura, K; Minami, H; Ohtsu, A; Ozawa, S; Saeki, M; Sai, K; Saijo, N; Saito, Y; Sawada, J; Shirao, K; Ueno, K; Yoshida, T	1
Gourgou-Bourgade, S; Kramar, A; Ychou, M	1
Brenner, B; Cordon-Cardo, C; Drobnjak, M; Gonen, M; Kelsen, DP; Kortmansky, J; Lefkowitz, R; Motwani, M; O'Reilly, E; Saltz, L; Schwartz, GK; Shah, MA; Tong, W; Weyerbacher, A; Yi, S	1
Boige, V; Debaere, T; Ducreux, M; Hannoun, L; Hebbar, M; Magherini, E; Malka, D; Mignard, D; Poynard, T; Taïeb, J	1
Crews, KR	1
Cisar, LA; Compton, LD; Duncan, BA; Elfring, GL; Goel, R; Goldberg, RM; Gruia, G; Hammond, LA; Kuhn, JG; McGovren, JP; Miller, LL; Pirotta, N; Rothenberg, ML; Schaaf, LJ; Sharma, A; Tipping, SJ; Yin, D	1
Du, J; Feng, G; He, L; Li, X; Qin, S; Wang, L; Xing, Q; Xu, L; Xu, M; Yu, L; Zhang, A	1
Hahn, KK; Kolesar, JM; Wolff, JJ	1
Booth, BP; Gobburu, JV; Ibrahim, A; Innocenti, F; Johnson, JR; Mehta, M; Rahman, A; Ramchandani, RP; Ratain, MJ; Wang, Y	1
Fujiwara, Y; Fukui, T; Kunitoh, H; Nokihara, H; Ohe, Y; Sekine, I; Simmyo, Y; Tamura, T; Yamada, K; Yamamoto, N	1
Kado, S; Kaneda, N; Kato, I; Kurita, A; Matsumoto, T; Onoue, M; Uchida, K; Yokokura, T	1
Hirohashi, S; Kaniwa, N; Kurose, K; Ozawa, S; Saeki, M; Sai, K; Saijo, N; Saito, Y; Sakamoto, H; Sawada, J; Shirao, K; Yoshida, T	1
Barrett, J; Bernstein, ML; Blaney, SM; Bomgaars, L; Gupta, M; Mondick, J; Rosner, GL; Thompson, PA; Yu, A	1
Chen, PM; Chen, WS; Chiou, TJ; Jiang, JK; Lin, JK; Lin, TC; Liu, CY; Liu, JH; Wang, HS; Wang, WS	1
Ehmer, U; Lankisch, TO; Manns, MP; Strassburg, CP	1
Chen, P; Das, S; Dolan, ME; Innocenti, F; Kroetz, DL; Ramírez, J; Ratain, MJ; Relling, M; Rosner, GL; Schuetz, E	1
Harada, M; Isobe, H; Izumi, K; Mino, K; Saito, K; Tanaka, H	1
Boeck, S; Heinemann, V; Schulz, C; Stemmler, HJ	1
Attinà, G; Coccia, P; Riccardi, R; Ruggiero, A; Scalzone, M	1
Strassburg, CP	1
Bubenzer, J; do O, N; Fuchs, R; Luedde, T; Roderburg, C; Spannbauer, M; Tischendorf, JJ; Trautwein, C	1
Auperin, A; Bize, P; de Baere, T; Denys, A; Deschamps, F; Drouard-Troalen, L; Paci, A; Pascale, F; Rao, PP; Seck, A; Teriitheau, C	1
Fukami, K; Hasegawa, J; Hirose, K; Kaneda, N; Kitamura, M; Maeda, Y; Maruo, E; Takada, H; Yamashita, K	1
Cao, J; Huang, XE; Liu, J; Lu, YY; Wang, L; Wu, XY; Xiang, J	1
Combalia, A; Dubreuil, M; Guañabens, N; Monegal, A; Parés, A; Peris, P; Ruiz-Gaspà, S	1
Azuma, S; Kawato, N; Makihara, K; Nakata, I; Ueno, H	1
Ando, Y; Fujita, K; Ichikawa, W; Minamimura, K; Miyauchi, H; Morita, S; Moriwaki, T; Nakamura, M; Ohashi, Y; Okutani, Y; Sadahiro, S; Sakata, Y; Shinozaki, K; Sugihara, M; Sugiyama, T; Takahashi, T; Takii, Y; Tanaka, C; Tsuji, A; Uehara, K	1
Hu, GY; Huang, L; Li, QX; Li, ZH; Liao, X; Liu, B; Qiu, H; Yu, QQ; Yuan, XL; Zhang, MS	1
Chen, CW; Huang, CW; Huang, MY; Lu, CY; Ma, CJ; Tsai, HL; Wang, JY; Wu, JY; Yeh, YS	1

Reviews

4 review(s) available for camptothecin and bilirubin

Article	Year
Pharmacogenetics and irinotecan therapy. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2006, Nov-15, Volume: 63, Issue:22 Topics: Antineoplastic Agents; Bilirubin; Biomarkers; Camptothecin; Clinical Trials as Topic; Colorectal Neoplasms; Diarrhea; Drug Labeling; Genetic Predisposition to Disease; Genetic Testing; Genotype; Glucuronosyltransferase; Humans; Irinotecan; Neutropenia; Pharmacogenetics; Polymorphism, Genetic; Practice Guidelines as Topic; Risk Assessment	2006
Family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A): from Gilbert's syndrome to genetic organization and variability. Archives of toxicology, 2008, Volume: 82, Issue:7 Topics: Antineoplastic Agents, Phytogenic; Atazanavir Sulfate; Bilirubin; Camptothecin; Genetic Variation; Gilbert Disease; Glucuronosyltransferase; HIV Protease Inhibitors; Humans; Irinotecan; Isoenzymes; Jaundice; Neoplasms; Oligopeptides; Pharmacogenetics; Pyridines; Risk Factors; Terminology as Topic	2008
UGT1A1 genotyping: a predictor of irinotecan-associated side effects and drug efficacy? Anti-cancer drugs, 2009, Volume: 20, Issue:10 Topics: Antineoplastic Agents, Phytogenic; Bilirubin; Biomarkers, Pharmacological; Camptothecin; Clinical Trials as Topic; Colorectal Neoplasms; Genotype; Glucuronosyltransferase; Humans; Inactivation, Metabolic; Irinotecan; Models, Biological; Neoplasm Metastasis; Polymorphism, Genetic; Precision Medicine; Racial Groups	2009
Hyperbilirubinemia syndromes (Gilbert-Meulengracht, Crigler-Najjar, Dubin-Johnson, and Rotor syndrome). Best practice & research. Clinical gastroenterology, 2010, Volume: 24, Issue:5 Topics: Animals; Antineoplastic Agents, Phytogenic; Bilirubin; Camptothecin; Crigler-Najjar Syndrome; Diagnosis, Differential; Genetic Predisposition to Disease; Genetic Variation; Gilbert Disease; Glucuronosyltransferase; Humans; Hyperbilirubinemia, Hereditary; Irinotecan; Jaundice, Chronic Idiopathic; Neoplasms	2010

Trials

7 trial(s) available for camptothecin and bilirubin

Article	Year
Dosage adjustment and pharmacokinetic profile of irinotecan in cancer patients with hepatic dysfunction. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2002, Nov-01, Volume: 20, Issue:21 Topics: Adult; Aged; Alkaline Phosphatase; Antineoplastic Agents, Phytogenic; Bilirubin; Camptothecin; Dose-Response Relationship, Drug; Female; Gastrointestinal Neoplasms; Humans; Hyperbilirubinemia; Irinotecan; Male; Middle Aged; Predictive Value of Tests	2002
Population pharmacokinetic model for irinotecan and two of its metabolites, SN-38 and SN-38 glucuronide. Clinical pharmacology and therapeutics, 2002, Volume: 72, Issue:6 Topics: Adult; Alkaline Phosphatase; Antineoplastic Agents, Phytogenic; Area Under Curve; Bilirubin; Camptothecin; Creatinine; Dose-Response Relationship, Drug; Drug Monitoring; Female; Glucuronates; Humans; Infusions, Intravenous; Irinotecan; Kidney Function Tests; Liver Function Tests; Male; Oxidoreductases; Predictive Value of Tests; Reproducibility of Results	2002
Phase III comparison of two irinotecan dosing regimens in second-line therapy of metastatic colorectal cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2003, Mar-01, Volume: 21, Issue:5 Topics: Adenocarcinoma; Aged; Antineoplastic Agents, Phytogenic; Bilirubin; Biomarkers, Tumor; Camptothecin; Colorectal Neoplasms; Disease Progression; Female; Humans; Irinotecan; Liver Neoplasms; Lung Neoplasms; Male; Prospective Studies; Quality of Life; Salvage Therapy; Survival Rate; Topoisomerase I Inhibitors; Treatment Outcome	2003
A phase I clinical trial of the sequential combination of irinotecan followed by flavopiridol. Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, May-15, Volume: 11, Issue:10 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bilirubin; Camptothecin; Cell Cycle Proteins; Cyclin-Dependent Kinase Inhibitor p21; Drug Administration Schedule; Drug Interactions; Female; Flavonoids; Humans; Intracellular Signaling Peptides and Proteins; Irinotecan; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Piperidines; Treatment Outcome; Tumor Suppressor Protein p53	2005
Irinotecan as first-line chemotherapy in patients with advanced hepatocellular carcinoma: a multicenter phase II study with dose adjustment according to baseline serum bilirubin level. European journal of cancer (Oxford, England : 1990), 2006, Volume: 42, Issue:4 Topics: Adolescent; Adult; Antineoplastic Agents, Phytogenic; Bilirubin; Biomarkers; Camptothecin; Carcinoma, Hepatocellular; Disease Progression; Dose-Response Relationship, Drug; Female; Humans; Irinotecan; Liver Cirrhosis; Liver Neoplasms; Male	2006
Phase 1 and pharmacokinetic study of intravenous irinotecan in refractory solid tumor patients with hepatic dysfunction. Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Jun-15, Volume: 12, Issue:12 Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Area Under Curve; Bilirubin; Camptothecin; Diarrhea; Female; Humans; Infusions, Intravenous; Irinotecan; Liver Diseases; Liver Function Tests; Male; Metabolic Clearance Rate; Middle Aged; Neoplasms; Neutropenia; Patient Selection	2006
Predictive effects of bilirubin on response of colorectal cancer to irinotecan-based chemotherapy. World journal of gastroenterology, 2016, Apr-28, Volume: 22, Issue:16 Topics: Adenocarcinoma; Adolescent; Adult; Aged; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Bilirubin; Biomarkers, Tumor; Camptothecin; Chi-Square Distribution; China; Colorectal Neoplasms; Female; Genotype; Glucuronosyltransferase; Humans; Irinotecan; Logistic Models; Longitudinal Studies; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Pharmacogenomic Variants; Phenotype; Predictive Value of Tests; Prospective Studies; ROC Curve; Treatment Outcome; Young Adult	2016

Other Studies

28 other study(ies) available for camptothecin and bilirubin

Article	Year
Severe CPT-11 toxicity in patients with Gilbert's syndrome: two case reports. Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:10 Topics: Bilirubin; Camptothecin; Drug Administration Schedule; Drug Therapy, Combination; Enzyme Inhibitors; Female; Gilbert Disease; Glucuronosyltransferase; Humans; Irinotecan; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Topoisomerase I Inhibitors	1997
Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes. The Journal of clinical investigation, 1998, Feb-15, Volume: 101, Issue:4 Topics: Animals; Antineoplastic Agents, Phytogenic; Bilirubin; Camptothecin; Causality; Crigler-Najjar Syndrome; Glucuronosyltransferase; Guanine; Humans; Irinotecan; Isoenzymes; Microsomes, Liver; Nitrophenols; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Uridine Diphosphate; Zidovudine	1998
Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism. Clinical pharmacology and therapeutics, 1999, Volume: 65, Issue:5 Topics: Antineoplastic Agents, Phytogenic; Bilirubin; Camptothecin; Genotype; Glucuronosyltransferase; Humans; Irinotecan; Liver; Phenotype; Polymorphism, Genetic; Promoter Regions, Genetic	1999
Polymorphisms of UDP-glucuronosyltransferase and pharmacokinetics of irinotecan. Therapeutic drug monitoring, 2002, Volume: 24, Issue:1 Topics: Adult; Antineoplastic Agents, Phytogenic; Area Under Curve; Bilirubin; Camptothecin; Enzyme Inhibitors; Female; Glucuronates; Glucuronosyltransferase; Humans; Infusions, Intravenous; Irinotecan; Male; Polymorphism, Genetic	2002
Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups. Pharmacogenetics, 2002, Volume: 12, Issue:9 Topics: Base Sequence; Bilirubin; Black or African American; Camptothecin; Genotype; Glucuronides; Glucuronosyltransferase; Haplotypes; Humans; Irinotecan; Linkage Disequilibrium; Microsomes, Liver; Molecular Sequence Data; Phenobarbital; Polymorphism, Genetic; Promoter Regions, Genetic; Topoisomerase I Inhibitors; White People	2002
Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Apr-15, Volume: 22, Issue:8 Topics: Antineoplastic Agents, Phytogenic; Bilirubin; Camptothecin; Female; Genetic Variation; Genotype; Glucuronosyltransferase; Humans; Irinotecan; Male; Neutropenia; Prospective Studies; Risk; Topoisomerase I Inhibitors	2004
Relationship of baseline serum bilirubin to efficacy and toxicity of single-agent irinotecan in patients with metastatic colorectal cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Apr-15, Volume: 22, Issue:8 Topics: Aged; Antineoplastic Agents, Phytogenic; Bilirubin; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Enzyme Inhibitors; Female; Humans; Irinotecan; Male; Middle Aged; Neoplasm Metastasis; Topoisomerase I Inhibitors	2004
UGT1A1 haplotypes associated with reduced glucuronidation and increased serum bilirubin in irinotecan-administered Japanese patients with cancer. Clinical pharmacology and therapeutics, 2004, Volume: 75, Issue:6 Topics: Aged; Bilirubin; Camptothecin; Female; Genetic Linkage; Glucuronides; Glucuronosyltransferase; Haplotypes; Humans; Irinotecan; Japan; Male; Middle Aged; Neoplasms; Polymorphism, Single Nucleotide	2004
Relationship of serum bilirubin to toxicity in patients with metastatic colorectal cancer treated with single-agent high-dose irinotecan. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Jan-20, Volume: 23, Issue:3 Topics: Antineoplastic Agents, Phytogenic; Bilirubin; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Humans; Irinotecan; Monitoring, Physiologic; Neutropenia; Reproducibility of Results	2005
Individualizing chemotherapeutic treatment of colorectal cancer. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2006, May-01, Volume: 63, Issue:9 Suppl 2 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bilirubin; Biomarkers, Tumor; Camptothecin; Cetuximab; Colorectal Neoplasms; Dihydropyrimidine Dehydrogenase Deficiency; Fluorouracil; Glucuronosyltransferase; Humans; Irinotecan; Pharmacogenetics; United States	2006
Intra-ethnic differences in genetic variants of the UGT-glucuronosyltransferase 1A1 gene in Chinese populations. The pharmacogenomics journal, 2007, Volume: 7, Issue:5 Topics: Adult; Antineoplastic Agents, Phytogenic; Asian People; Bilirubin; Bone Marrow Diseases; Camptothecin; China; Ethnicity; Exons; Female; Gastrointestinal Diseases; Gene Frequency; Genetic Predisposition to Disease; Glucuronosyltransferase; Haplotypes; Heterozygote; Homozygote; Humans; Hyperbilirubinemia; Irinotecan; Linkage Disequilibrium; Male; Middle Aged; Phenotype; Polymorphism, Genetic; Reference Values; TATA Box	2007
The role of SN-38 exposure, UGT1A128 polymorphism, and baseline bilirubin level in predicting severe irinotecan toxicity. Journal of clinical pharmacology, 2007, Volume: 47, Issue:1* Topics: Antineoplastic Agents, Phytogenic; Area Under Curve; Bilirubin; Camptothecin; Female; Glucuronosyltransferase; Humans; Irinotecan; Lymphoma; Male; Models, Biological; Neutropenia; Polymorphism, Genetic; Regression Analysis	2007
Serum total bilirubin as a predictive factor for severe neutropenia in lung cancer patients treated with cisplatin and irinotecan. Japanese journal of clinical oncology, 2007, Volume: 37, Issue:5 Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Bilirubin; Camptothecin; Cisplatin; Diarrhea; Female; Humans; Irinotecan; Lung Neoplasms; Male; Middle Aged; Neutropenia; Retrospective Studies	2007
Involvement of UDP-glucuronosyltransferase activity in irinotecan-induced delayed-onset diarrhea in rats. Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:4 Topics: Algorithms; Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Bilirubin; Camptothecin; Crigler-Najjar Syndrome; Diarrhea; Glucuronosyltransferase; Hyperbilirubinemia; Intestines; Irinotecan; Rats; Rats, Gunn; Rats, Wistar	2008
Importance of UDP-glucuronosyltransferase 1A16 for irinotecan toxicities in Japanese cancer patients. Cancer letters, 2008, Mar-18, Volume: 261, Issue:2* Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Asian People; Bilirubin; Camptothecin; Female; Genotype; Glucuronosyltransferase; Humans; Incidence; Irinotecan; Japan; Male; Middle Aged; Neoplasms; Polymorphism, Genetic; Retrospective Studies	2008
Pharmacokinetics of irinotecan and its metabolites in pediatric cancer patients: a report from the children's oncology group. Cancer chemotherapy and pharmacology, 2008, Volume: 62, Issue:6 Topics: Adolescent; Adult; Antineoplastic Agents; Area Under Curve; Bilirubin; Camptothecin; Child; Child, Preschool; Clinical Trials, Phase II as Topic; Computer Simulation; Cytochrome P-450 CYP3A; Female; Glucuronates; Glucuronosyltransferase; Humans; Infant; Infusions, Intravenous; Irinotecan; Male; Metabolic Clearance Rate; Models, Biological; Multicenter Studies as Topic; Neoplasms	2008
UGT1A128 polymorphism predicts irinotecan-induced severe toxicities without affecting treatment outcome and survival in patients with metastatic colorectal carcinoma. Cancer, 2008, May-01, Volume: 112, Issue:9* Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Bilirubin; Camptothecin; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Female; Glucuronosyltransferase; Humans; Irinotecan; Male; Middle Aged; Neoplasm Metastasis; Polymorphism, Genetic; Retrospective Studies	2008
Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009, Jun-01, Volume: 27, Issue:16 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Bilirubin; Biotransformation; Camptothecin; Colorectal Neoplasms; Drug Administration Schedule; Female; Genetic Predisposition to Disease; Glucuronides; Glucuronosyltransferase; Hepatocyte Nuclear Factor 1-alpha; Humans; Irinotecan; Liver-Specific Organic Anion Transporter 1; Male; Middle Aged; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Multivariate Analysis; Neutropenia; Organic Anion Transporters; Patient Selection; Phenotype; Polymorphism, Genetic; Risk Assessment; Risk Factors; Treatment Outcome	2009
[Assessment of total bilirubin or SN-38/SN-38G ratio as a predictor of severe irinotecan toxicity]. Gan to kagaku ryoho. Cancer & chemotherapy, 2009, Volume: 36, Issue:9 Topics: Aged; Antineoplastic Agents, Phytogenic; Bilirubin; Camptothecin; Carcinoma, Non-Small-Cell Lung; Chromatography, High Pressure Liquid; Female; Glucuronates; Humans; Individuality; Irinotecan; Lung Neoplasms; Male; Middle Aged; Small Cell Lung Carcinoma	2009
Treatment of childhood sarcoma with irinotecan: bilirubin level as a predictor of gastrointestinal toxicity. Journal of chemotherapy (Florence, Italy), 2009, Volume: 21, Issue:6 Topics: Adolescent; Antineoplastic Agents, Phytogenic; Bilirubin; Camptothecin; Child; Child, Preschool; Diarrhea; Female; Gastric Mucosa; Humans; Infant; Intestinal Mucosa; Irinotecan; Male; Predictive Value of Tests; Retrospective Studies; Sarcoma; Soft Tissue Neoplasms	2009
Safe use of FOLFOX in two patients with metastatic colorectal carcinoma and severe hepatic dysfunction. Clinical colorectal cancer, 2011, Mar-01, Volume: 10, Issue:1 Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bilirubin; Camptothecin; Colorectal Neoplasms; Disease Progression; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Liver Neoplasms; Male; Organoplatinum Compounds; Oxaliplatin	2011
Irinotecan loaded in eluting beads: preclinical assessment in a rabbit VX2 liver tumor model. Cardiovascular and interventional radiology, 2012, Volume: 35, Issue:6 Topics: Alanine Transaminase; Animals; Antineoplastic Agents, Phytogenic; Aspartate Aminotransferases; Bilirubin; Camptothecin; Chemoembolization, Therapeutic; Drug Delivery Systems; Infusions, Intra-Arterial; Infusions, Intravenous; Irinotecan; Liver Neoplasms, Experimental; Rabbits; Statistics, Nonparametric	2012
Usefulness of one-point plasma SN-38G/SN-38 concentration ratios as a substitute for UGT1A1 genetic information after irinotecan administration. International journal of clinical oncology, 2014, Volume: 19, Issue:2 Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Bilirubin; Camptothecin; Colorectal Neoplasms; Female; Glucuronates; Glucuronosyltransferase; Humans; Irinotecan; Male; Middle Aged; Neutropenia; Polymorphism, Genetic	2014
Clinical observations on associations between the UGT1A1 genotype and severe toxicity of irinotecan. Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:7 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Bilirubin; Camptothecin; Diarrhea; Female; Genotype; Glucuronosyltransferase; Humans; Irinotecan; Male; Middle Aged; Neoplasms; Neutropenia; Young Adult	2014
Ursodeoxycholic acid decreases bilirubin-induced osteoblast apoptosis. European journal of clinical investigation, 2014, Volume: 44, Issue:12 Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Bilirubin; Camptothecin; Cell Line, Tumor; Cholagogues and Choleretics; Detergents; Humans; Lithocholic Acid; Osteoblasts; Up-Regulation; Ursodeoxycholic Acid	2014
Pre-treatment serum total bilirubin level as an indicator of optimal CPT-11 dosage. Cancer chemotherapy and pharmacology, 2015, Volume: 75, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Bilirubin; Biomarkers; Camptothecin; Female; Genotype; Glucuronosyltransferase; Humans; Irinotecan; Male; Middle Aged; Neoplasms; Polymorphism, Genetic; Predictive Value of Tests; Retrospective Studies	2015
An internally and externally validated nomogram for predicting the risk of irinotecan-induced severe neutropenia in advanced colorectal cancer patients. British journal of cancer, 2015, May-12, Volume: 112, Issue:10 Topics: Aged; Alleles; Asian People; Bilirubin; Camptothecin; Colorectal Neoplasms; Female; Genetic Predisposition to Disease; Genotype; Glucuronosyltransferase; Humans; Irinotecan; Male; Middle Aged; Neutropenia; Neutrophils; Nomograms; Prospective Studies	2015
Patients with Metastatic Colorectal Cancer and Hyperbilirubinemia Treated with FOLFIRI plus Bevacizumab as First-Line Treatment. Chemotherapy, 2017, Volume: 62, Issue:1 Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Bilirubin; Bone Neoplasms; Camptothecin; Colorectal Neoplasms; Disease-Free Survival; Fluorouracil; Genotype; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Leucovorin; Liver Neoplasms; Male; Middle Aged; Prospective Studies; Survival Rate	2017