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camptothecin and benzyloxycarbonylleucyl-leucyl-leucine aldehyde

camptothecin has been researched along with benzyloxycarbonylleucyl-leucyl-leucine aldehyde in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (42.86)29.6817
2010's6 (42.86)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Fan, JT; Li, J; Li, Y; Peng, YM; Su, J; Tan, NH; Yan, H; Zeng, GZ; Zhou, YB1
Ilaš, J; Kikelj, D; Skok, Ž; Zidar, N1
Bukowski, RM; Ganapathi, MK; Ganapathi, R; Grabowski, DR; Tabata, M; Tabata, R1
Ganapathi, R; Tabata, M1
Ahn, JS; Bae, EY; He, L; Jeong, SJ; Kim, A; Kim, BY; Kim, CH; Kim, KE; Kim, SO; Kwon, OS; Lee, MS; Moon, A; Shim, JH; Yoon, DY1
Furukawa, T; Ishikawa, T; Morishima, Y; Nakagawa, H; Osawa, Y; Tamura, A; Wakabayashi, K1
Fukuda, M; Koike, A; Ohta, T; Takeshita, T; Wu, W1
Brodie, KM; Henderson, BR1
Abe, M; Harada, M; Itou, M; Kawaguchi, T; Koga, H; Kuromatsu, R; Okuda, K; Sakata, M; Sata, M; Sumie, S; Taniguchi, E; Ueno, T; Yamagishi, S1
Sakasai, R; Teraoka, H; Tibbetts, RS1
Jaeger, C; Kratz, F; Merfort, I; Naumann, K; Schmich, K1
Ikeda, M; Ishida, K; Kume, K; Nishizuka, SS; Shimura, T; Takemoto, K; Young, L1
Chen, Q; Hu, J; Liu, J; Luo, X; Meng, Z; Ni, Z; Sun, Y; Tang, L; Wang, X; Xiang, F; Zhang, M; Zhang, Z; Zhu, L1

Reviews

1 review(s) available for camptothecin and benzyloxycarbonylleucyl-leucyl-leucine aldehyde

ArticleYear
Dual Inhibitors of Human DNA Topoisomerase II and Other Cancer-Related Targets.
    Journal of medicinal chemistry, 2020, 02-13, Volume: 63, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; DNA Topoisomerases, Type II; Drug Design; HSP90 Heat-Shock Proteins; Humans; Neoplasms; Topoisomerase II Inhibitors; Tubulin Modulators

2020

Other Studies

13 other study(ies) available for camptothecin and benzyloxycarbonylleucyl-leucyl-leucine aldehyde

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Rubiyunnanins C-H, cytotoxic cyclic hexapeptides from Rubia yunnanensis inhibiting nitric oxide production and NF-κB activation.
    Bioorganic & medicinal chemistry, 2010, Dec-01, Volume: 18, Issue:23

    Topics: Animals; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Interferon-gamma; Lipopolysaccharides; Mice; NF-kappa B; Nitric Oxide; Oligopeptides; Peptides, Cyclic; Plant Roots; Protein Structure, Tertiary; Rubia; Tumor Necrosis Factor-alpha

2010
Roles of NF-kappaB and 26 S proteasome in apoptotic cell death induced by topoisomerase I and II poisons in human nonsmall cell lung carcinoma.
    The Journal of biological chemistry, 2001, Mar-16, Volume: 276, Issue:11

    Topics: Apoptosis; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cisplatin; DNA; DNA Damage; DNA-Binding Proteins; Enzyme Inhibitors; Etoposide; Humans; I-kappa B Proteins; Irinotecan; Leupeptins; Lung Neoplasms; NF-kappa B; NF-KappaB Inhibitor alpha; Paclitaxel; Peptide Hydrolases; Proteasome Endopeptidase Complex; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

2001
NF-kappa B activation in topoisomerase I inhibitor-induced apoptotic cell death in human non-small cell lung cancer.
    Annals of the New York Academy of Sciences, 2000, Volume: 922

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camptothecin; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Enzyme Inhibitors; Humans; I-kappa B Proteins; Irinotecan; Leupeptins; Lung Neoplasms; NF-kappa B; NF-KappaB Inhibitor alpha; Topoisomerase I Inhibitors; Transfection; Tumor Cells, Cultured

2000
Caspase-3 activation as a key factor for HBx-transformed cell death.
    Cell proliferation, 2008, Volume: 41, Issue:5

    Topics: Camptothecin; Caspase 3; Cell Death; Cell Line, Transformed; Cell Proliferation; Cell Survival; Endoplasmic Reticulum; Enzyme Activation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Leupeptins; NF-kappa B; Oligopeptides; Proto-Oncogene Proteins c-akt; Signal Transduction; Trans-Activators; Transcriptional Activation; Viral Regulatory and Accessory Proteins

2008
Major SNP (Q141K) variant of human ABC transporter ABCG2 undergoes lysosomal and proteasomal degradations.
    Pharmaceutical research, 2009, Volume: 26, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Camptothecin; Cell Line; Cell Survival; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Humans; Immunoblotting; Irinotecan; Leupeptins; Lysosomes; Macrolides; Microscopy, Fluorescence; Neoplasm Proteins; Polymorphism, Single Nucleotide; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Stability; RNA, Messenger; Time Factors; Ubiquitin

2009
Perturbation of DNA repair pathways by proteasome inhibitors corresponds to enhanced chemosensitivity of cells to DNA damage-inducing agents.
    Cancer chemotherapy and pharmacology, 2009, Volume: 64, Issue:5

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Cell Nucleus; Cell Survival; Comet Assay; DNA Damage; DNA Repair; Epirubicin; Female; HeLa Cells; Humans; Immunohistochemistry; Irinotecan; Leupeptins; Oligopeptides; Proteasome Inhibitors; Ubiquitin

2009
Differential modulation of BRCA1 and BARD1 nuclear localisation and foci assembly by DNA damage.
    Cellular signalling, 2010, Volume: 22, Issue:2

    Topics: Active Transport, Cell Nucleus; Apoptosis; BRCA1 Protein; Camptothecin; Cell Line, Tumor; Cell Nucleolus; DNA Damage; DNA Repair; Down-Regulation; Etoposide; Humans; Leupeptins; Phosphorylation; Radiation, Ionizing; RNA, Small Interfering; Tumor Suppressor Proteins; Ubiquitin-Protein Ligases; Ultraviolet Rays

2010
Pigment epithelium-derived factor inhibits lysosomal degradation of Bcl-xL and apoptosis in HepG2 cells.
    The American journal of pathology, 2010, Volume: 176, Issue:1

    Topics: Apoptosis; bcl-X Protein; Camptothecin; Carcinoma, Hepatocellular; Cell Cycle; Cyclophilins; Densitometry; Eye Proteins; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Hep G2 Cells; Humans; Leupeptins; Liver; Liver Neoplasms; Lysosomes; Macrolides; Nerve Growth Factors; Protein Processing, Post-Translational; Recombinant Proteins; RNA, Messenger; Serpins

2010
Proteasome inhibition suppresses DNA-dependent protein kinase activation caused by camptothecin.
    DNA repair, 2010, Jan-02, Volume: 9, Issue:1

    Topics: Camptothecin; Cell Line, Tumor; Cyclin-Dependent Kinases; DNA Replication; DNA-Activated Protein Kinase; Enzyme Activation; Humans; Leupeptins; Phosphorylation; Protease Inhibitors; Proteasome Inhibitors; Replication Protein A

2010
Noxa/Mcl-1 balance influences the effect of the proteasome inhibitor MG-132 in combination with anticancer agents in pancreatic cancer cell lines.
    Anti-cancer drugs, 2012, Volume: 23, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Caspase 3; Caspase 7; Cell Line, Tumor; Doxorubicin; Humans; Leupeptins; Myeloid Cell Leukemia Sequence 1 Protein; NF-kappa B; Paclitaxel; Pancreatic Neoplasms; Proteasome Inhibitors; Proto-Oncogene Proteins c-bcl-2

2012
Systematic Protein Level Regulation via Degradation Machinery Induced by Genotoxic Drugs.
    Journal of proteome research, 2016, Jan-04, Volume: 15, Issue:1

    Topics: Apoptosis; Camptothecin; Cisplatin; DNA Damage; Fluorouracil; HCT116 Cells; Humans; Irinotecan; Leupeptins; Mutagens; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteolysis; Proteome

2016
Decreasing Arl4c expression by inhibition of AKT signal in human lung adenocarcinoma cells.
    Life sciences, 2020, Apr-01, Volume: 246

    Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; ADP-Ribosylation Factors; Blotting, Western; Camptothecin; Cell Line, Tumor; Chromones; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Leupeptins; Lung Neoplasms; Morpholines; Proto-Oncogene Proteins c-akt; Signal Transduction; Smoking

2020