camptothecin has been researched along with asparagine in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Bjornsti, MA; Fertala, J; Pommier, Y; Pourquier, P; Vance, JR | 1 |
| Bencharit, S; Danks, MK; Howard-Williams, EL; Morton, CL; Potter, PM; Redinbo, MR | 1 |
| Ando, M; Hanioka, N; Jinno, H; Kaniwa, N; Minami, H; Ohtsu, A; Ozawa, S; Saeki, M; Sai, K; Saijo, N; Saito, Y; Sawada, J; Shirao, K; Tanaka-Kagawa, T; Yoshida, T | 1 |
| Bjornsti, MA; Burgin, AB; Colley, WC; van der Merwe, M; Vance, JR | 1 |
| Balaña-Fouce, R; Diaz-González, R; Pérez-Pertejo, Y; Pommier, Y; Reguera, RM | 1 |
| Adachi, S; Anai, H; Hanada, K; Ishizaki, T; Kawano, M; Matsuoka, S; Nishida, M; Nishida, Y; Okuma, T; Tanaka, K; Terabayashi, T; Tomo, T; Tsumura, H | 1 |
6 other study(ies) available for camptothecin and asparagine
| Article | Year |
|---|---|
Substitutions of Asn-726 in the active site of yeast DNA topoisomerase I define novel mechanisms of stabilizing the covalent enzyme-DNA intermediate.
Topics: Amino Acid Substitution; Asparagine; Base Sequence; Binding Sites; Camptothecin; DNA Topoisomerases, Type I; Enzyme Stability; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Plasmids; Saccharomyces cerevisiae; Substrate Specificity | 2000 |
Structural insights into CPT-11 activation by mammalian carboxylesterases.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents, Phytogenic; Asparagine; Binding Sites; Camptothecin; Carboxylic Ester Hydrolases; Crystallography, X-Ray; Glycosylation; Irinotecan; Liver; Models, Molecular; Molecular Sequence Data; Pliability; Prodrugs; Rabbits; Structure-Activity Relationship | 2002 |
Functional characterization of human UDP-glucuronosyltransferase 1A9 variant, D256N, found in Japanese cancer patients.
Topics: Amino Acid Substitution; Animals; Antineoplastic Agents; Asparagine; Aspartic Acid; Camptothecin; COS Cells; Exons; Genetic Variation; Glucuronates; Glucuronic Acid; Glucuronosyltransferase; Humans; Irinotecan; Japan; Mutation; Neoplasms; Polymorphism, Single Nucleotide; Transfection; UDP-Glucuronosyltransferase 1A9 | 2003 |
Substitution of conserved residues within the active site alters the cleavage religation equilibrium of DNA topoisomerase I.
Topics: Asparagine; Binding Sites; Camptothecin; Conserved Sequence; DNA; DNA Topoisomerases, Type I; DNA, Superhelical; Enzyme Inhibitors; Histidine; Mutagenesis; Phenylalanine; Saccharomyces cerevisiae; Structure-Activity Relationship; Tyrosine | 2004 |
Mutational study of the "catalytic tetrad" of DNA topoisomerase IB from the hemoflagellate Leishmania donovani: Role of Asp-353 and Asn-221 in camptothecin resistance.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Asparagine; Aspartic Acid; Base Sequence; Binding Sites; Camptothecin; Catalysis; DNA Primers; DNA Topoisomerases, Type I; Drug Resistance; Enzyme Inhibitors; Flagella; Leishmania donovani; Molecular Sequence Data; Mutagenesis, Site-Directed; Protozoan Proteins; Topoisomerase I Inhibitors | 2008 |
Mechanism of action of non-camptothecin inhibitor Genz-644282 in topoisomerase I inhibition.
Topics: Aphidicolin; Arginine; Asparagine; Camptothecin; DNA; DNA Topoisomerases, Type I; Naphthyridines; Tyrosine | 2022 |