camptothecin has been researched along with arc111 in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (90.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| LaVoie, EJ; Li, TK; Liu, A; Liu, LF; Ruchelman, AL; Singh, SK | 1 |
| LaVoie, EJ; Liu, A; Liu, LF; Ruchelman, AL; Zhou, N; Zhu, S | 1 |
| Feng, W; Lavoie, EJ; Liu, AA; Liu, LF; Satyanarayana, M; Tsai, YC | 4 |
| Cheng, L; Feng, W; LaVoie, EJ; Liu, AA; Liu, LF; Satyanarayana, M; Tsai, YC | 1 |
| Cheng, L; Feng, W; LaVoie, EJ; Liu, A; Liu, LF; Satyanarayana, M; Tsai, YC | 1 |
| Chan, YW; Chang, CL; Chang, LH; Chao, YT; Chen, SF; Chen, YC; Chen, YF; Chou, SY; Chuang, SH; Gao, YS; Hsu, PC; Hsueh, WY; Huang, GR; Huang, HY; Huang, JJ; Huang, MS; Huang, PH; Huang, SY; Huang, YC; Jian, BH; Kao, YF; Lai, CH; Lee, YE; Lin, HS; Lin, JC; Lin, SF; Lin, YH; Liu, HH; Lo, TH; Lu, YY; Teng, LW; Wang, SY; Wei, WY; Yang, SC; Yuan, TT | 1 |
| Agata, N; Bagley, RG; Battle, T; Crawford, J; Ewesuedo, R; Krumbholz, R; Kurtzberg, LS; Lavoie, EJ; Roth, S; Rouleau, C; Schmid, S; Teicher, BA; Wang, F; Yao, M; Yu, XJ | 1 |
10 other study(ies) available for camptothecin and arc111
| Article | Year |
|---|---|
Nitro and amino substitution in the D-ring of 5-(2-dimethylaminoethyl)- 2,3-methylenedioxy-5H-dibenzo[c,h][1,6]naphthyridin-6-ones: effect on topoisomerase-I targeting activity and cytotoxicity.
Topics: Amines; Antineoplastic Agents; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Naphthyridines; Nitro Compounds; Structure-Activity Relationship; Tumor Cells, Cultured | 2003 |
Dimethoxybenzo[i]phenanthridine-12-carboxylic acid derivatives and 6H-dibenzo[c,h][2,6]naphthyridin-5-ones with potent topoisomerase I-targeting activity and cytotoxicity.
Topics: Antineoplastic Agents; Carboxylic Acids; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Naphthyridines; Phenanthridines; Structure-Activity Relationship; Topoisomerase I Inhibitors | 2004 |
Facile formation of hydrophilic derivatives of 5H-8,9-dimethoxy-5-[2-(N,N-dimethylamino)ethyl]-2,3-methylenedioxydibenzo[c,h] [1,6]naphthyridin-6-one (ARC-111) and its 12-aza analog via quaternary ammonium intermediates.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; DNA Topoisomerases, Type I; Dose-Response Relationship, Drug; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Molecular Structure; Naphthyridines; Quaternary Ammonium Compounds; Stereoisomerism; Structure-Activity Relationship; Xenograft Model Antitumor Assays | 2008 |
Syntheses and biological evaluation of topoisomerase I-targeting agents related to 11-[2-(N,N-dimethylamino)ethyl]-2,3-dimethoxy-8,9-methylenedioxy-11H-isoquino[4,3-c]cinnolin-12-one (ARC-31).
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Female; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Mice, Nude; Neoplasms; Quinolones; Topoisomerase I Inhibitors; Xenograft Model Antitumor Assays | 2008 |
11-Substituted 2,3-dimethoxy-8,9-methylenedioxybenzo[i]phenanthridine derivatives as novel topoisomerase I-targeting agents.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; DNA Topoisomerases, Type I; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Leukemia, Lymphoid; Phenanthridines; Structure-Activity Relationship; Topoisomerase I Inhibitors | 2008 |
Synthesis of N-substituted 5-[2-(N-alkylamino)ethyl]dibenzo[c,h][1,6]naphthyridines as novel topoisomerase I-targeting antitumor agents.
Topics: Alkylation; Amines; Antineoplastic Agents; Benzene; Cell Line, Tumor; Cell Survival; DNA Topoisomerases, Type I; Enzyme Inhibitors; Humans; Molecular Structure; Naphthyridines; Structure-Activity Relationship; Topoisomerase I Inhibitors | 2008 |
Novel topoisomerase I-targeting antitumor agents synthesized from the N,N,N-trimethylammonium derivative of ARC-111, 5H-2,3-dimethoxy-8,9-methylenedioxy-5-[(2-N,N,N-trimethylammonium)ethyl]dibenzo[c,h][1,6]naphthyridin-6-one iodide.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Camptothecin; Cell Line, Tumor; DNA Topoisomerases, Type I; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Mice; Naphthyridines; Neoplasm Proteins; Structure-Activity Relationship | 2009 |
12-Substituted 2,3-dimethoxy-8,9-methylenedioxybenzo[i]phenanthridines as novel topoisomerase I-targeting antitumor agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; DNA Topoisomerases, Type I; Humans; Phenanthridines; Topoisomerase I Inhibitors | 2009 |
Copper(I)-Catalyzed Nitrile-Addition/
Topics: Animals; Antineoplastic Agents; Catalysis; Copper; DNA Topoisomerases, Type I; Drug Design; Drug Screening Assays, Antitumor; Female; Humans; Male; Mice; Mice, Nude; Models, Molecular; Molecular Docking Simulation; Nitriles; Quinolones; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Topoisomerase I Inhibitors; Xenograft Model Antitumor Assays | 2021 |
Bone marrow and tumor cell colony-forming units and human tumor xenograft efficacy of noncamptothecin and camptothecin topoisomerase I inhibitors.
Topics: Animals; Antineoplastic Agents; Body Weight; Bone Marrow; Camptothecin; Cell Line, Tumor; Cell Proliferation; Confidence Intervals; Dose-Response Relationship, Drug; Flow Cytometry; Humans; Inhibitory Concentration 50; Irinotecan; Male; Mice; Mice, Inbred BALB C; Naphthyridines; Neoplastic Stem Cells; Topoisomerase I Inhibitors; Topotecan; Weight Loss; Xenograft Model Antitumor Assays | 2008 |