Page last updated: 2024-08-22

camptothecin and amonafide

camptothecin has been researched along with amonafide in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (18.18)18.2507
2000's3 (27.27)29.6817
2010's5 (45.45)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Chen, Z; Qian, X; Tan, S; Xu, Y; Yin, H1
Chen, Z; Li, H; Li, Q; Liu, J; Lyu, J; Qian, X; Sun, D; Sun, X; Tan, S; Wang, X; Wu, F; Xu, Y; Yang, Y1
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR1
Ben-David, G; Firer, MA; Gancz, A; Gellerman, G; Gilad, Y; Luboshits, G; Minnes, R; Senderowitz, H; Tuchinsky, H1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1
Diasio, RB; Stagg, MP1
Burris, HA; Eckardt, JR; Fields, S; O'Rourke, T; Rodriguez, GI; Rothenberg, ML; Weiss, GR1
Innocenti, F; Iyer, L; Ratain, MJ2
Darro, F; Dewelle, J; Dumont, P; El Yazidi, M; Gaussin, JF; Kiss, R; Lefranc, F; Mahieu, T; Mijatovic, T; Ribaucour, F; Sauvage, S; Simon, G; Tuti, J; Van Quaquebeke, E; Van Vynckt, F1

Reviews

3 review(s) available for camptothecin and amonafide

ArticleYear
Novel chemotherapeutic agents in early clinical development.
    Current opinion in oncology, 1990, Volume: 2, Issue:6

    Topics: Adenine; Alkaloids; Anthraquinones; Antineoplastic Agents; Biphenyl Compounds; Camptothecin; Humans; Imides; Irinotecan; Isoquinolines; Naphthalimides; Neoplasms; Organophosphonates; Paclitaxel; Pyrazoles; Quinazolines; Sulfonylurea Compounds; Terpenes; Trimetrexate

1990
New anticancer agents.
    Cancer chemotherapy and biological response modifiers, 1994, Volume: 15

    Topics: Adenine; Animals; Antineoplastic Agents; Camptothecin; Deoxycytidine; Gemcitabine; Humans; Imides; Indoles; Irinotecan; Isoquinolines; Naphthalimides; Organophosphonates; Pyridines; Topotecan; Vinblastine; Vinorelbine

1994
Pharmacogenetics: a tool for individualizing antineoplastic therapy.
    Clinical pharmacokinetics, 2000, Volume: 39, Issue:5

    Topics: Adenine; Antineoplastic Agents; Camptothecin; Dihydrouracil Dehydrogenase (NADP); Fluorouracil; Genotype; Glucuronosyltransferase; Humans; Imides; Irinotecan; Isoquinolines; Mercaptopurine; Methyltransferases; Naphthalimides; Organophosphonates; Oxidoreductases; Pharmacogenetics; Phenotype

2000

Trials

1 trial(s) available for camptothecin and amonafide

ArticleYear
Novel chemotherapeutic agents in early clinical development.
    Current opinion in oncology, 1990, Volume: 2, Issue:6

    Topics: Adenine; Alkaloids; Anthraquinones; Antineoplastic Agents; Biphenyl Compounds; Camptothecin; Humans; Imides; Irinotecan; Isoquinolines; Naphthalimides; Neoplasms; Organophosphonates; Paclitaxel; Pyrazoles; Quinazolines; Sulfonylurea Compounds; Terpenes; Trimetrexate

1990

Other Studies

8 other study(ies) available for camptothecin and amonafide

ArticleYear
Oxo-heterocyclic fused naphthalimides as antitumor agents: synthesis and biological evaluation.
    European journal of medicinal chemistry, 2013, Volume: 62

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Heterocyclic Compounds; Humans; Mice; Molecular Structure; Naphthalimides; Structure-Activity Relationship

2013
Antiproliferative and apoptosis-inducing activities of novel naphthalimide-cyclam conjugates through dual topoisomerase (topo) I/II inhibition.
    Bioorganic & medicinal chemistry, 2015, Sep-01, Volume: 23, Issue:17

    Topics: Apoptosis; Heterocyclic Compounds; Humans; Molecular Structure; Naphthalimides; Topoisomerase II Inhibitors

2015
Highly predictive and interpretable models for PAMPA permeability.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine

2017
Discovery of potent molecular chimera (CM358) to treat human metastatic melanoma.
    European journal of medicinal chemistry, 2017, Sep-29, Volume: 138

    Topics: Animals; Antineoplastic Agents; Cell Proliferation; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Heterocyclic Compounds, 3-Ring; Humans; Melanoma; Mice; Mice, Nude; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Pyrimidinones; Structure-Activity Relationship; Topoisomerase II Inhibitors

2017
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020
Pharmacogenetics of anticancer agents: lessons from amonafide and irinotecan.
    Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:4 Pt 2

    Topics: Adenine; Antineoplastic Agents; Camptothecin; Humans; Imides; Irinotecan; Isoquinolines; Naphthalimides; Organophosphonates; Pharmacogenetics; Polymorphism, Genetic

2001
2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin- 5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity.
    Journal of medicinal chemistry, 2007, Aug-23, Volume: 50, Issue:17

    Topics: Acetamides; Adenine; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Camptothecin; Cell Line, Tumor; Cellular Senescence; Deoxycytidine; Drug Screening Assays, Antitumor; Erythrocyte Count; Female; Gemcitabine; Humans; Imides; Irinotecan; Isoquinolines; Leukocyte Count; Maximum Tolerated Dose; Mice; Naphthalimides; Neoplasm Transplantation; Organophosphonates; Platelet Count; Structure-Activity Relationship; Topoisomerase I Inhibitors; Urea

2007