camptothecin has been researched along with acridines in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kann, HE; Kohn, KW | 1 |
| Baguley, BC; Finlay, GJ | 1 |
| Baguley, BC; Bridewell, DJ; Finlay, GJ | 1 |
| Beijnen, JH; de Jong, LA; Hausheer, FH; Maliepaard, M; Pluim, D; Schellens, JH; Tohgo, A; van Gastelen, MA; van Waardenburg, RC | 1 |
| Boven, E; Hoogsteen, IJ; Kohlhagen, G; Maliepaard, M; Pinedo, HM; Pommier, Y; Scheffer, GL; Scheper, RJ; Schlüper, HM; van Hattum, AH | 1 |
| Assaraf, YG; Bram, EE; Grimberg, M; Ifergan, I; Lemke, K; Skladanowski, A | 1 |
| Fukuda, S; Kojiro, M; Nakashima, O; Ookawa, K; Sakata, Y; Suto, K; Takahata, T; Tamura, Y; Tanaka, M; Tateishi, T; Yano, H | 1 |
| Antoniani, B; Biroccio, A; D'Incalci, M; Frapolli, R; Gilson, E; Leonetti, C; Mottolese, M; Riggio, G; Rizzo, A; Salvati, E; Scarsella, M; Staszewsky, L; Stevens, MF; Stoppacciaro, A; Zupi, G | 1 |
| Choi, MK; Chung, SJ; Jin, QR; Kim, DD; Shim, CK; Shim, WS; Song, IS; Tian, GY; Yang, SG | 1 |
| Arnaud, O; Bates, SE; Boumendjel, A; Di Pietro, A; Dumontet, C; Falson, P; Gèze, A; Guitton, J; Honorat, M; Matera, EL; Payen, L; Stein, WD | 1 |
| Beretta, G; Biroccio, A; D'Angelo, C; Franceschin, M; Gilson, E; Leonetti, C; Orlandi, A; Passeri, D; Pisano, C; Porru, M; Rizzo, A; Salvati, E; Stevens, MF; Zunino, F; Zupi, G | 1 |
| Adane, ED; Anderson, BD; Leggas, M; Liu, Z; Xiang, TX | 1 |
| Beijnen, JH; Iusuf, D; Lin, F; Marchetti, S; Mazzanti, R; Pluim, D; Schellens, JH; van Tellingen, O | 1 |
| Bejrowska, A; Mazerska, Z; Mróz, A; Pawłowska, M | 1 |
14 other study(ies) available for camptothecin and acridines
| Article | Year |
|---|---|
Effects of deoxyribonucleic acid-reactive drugs on ribonucleic acid synthesis in leukemia L1210 cells.
Topics: Acridines; Acrylamides; Alkaloids; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzazepines; Camptothecin; Carbazoles; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Centrifugation, Density Gradient; Dactinomycin; Daunorubicin; Deoxyadenosines; DNA, Neoplasm; Ethidium; Leukemia L1210; Mechlorethamine; Methionine; Phenanthridines; Pyridines; Pyrroles; RNA, Neoplasm; Tritium; Uridine | 1972 |
Pharmacokinetic/cytokinetic principles in the chemotherapy of solid tumours.
Topics: Acridines; Antineoplastic Agents; Camptothecin; Cell Cycle; Drug Design; Drug Screening Assays, Antitumor; Humans; Leukemia; Paclitaxel; Tumor Cells, Cultured | 1995 |
Mechanism of cytotoxicity of N-[2-(dimethylamino)ethyl] acridine-4-carboxamide and of its 7-chloro derivative: the roles of topoisomerases I and II.
Topics: Acridines; Amsacrine; Animals; Antineoplastic Agents; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Survival; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Enzyme Inhibitors; Humans; Kinetics; Lung Neoplasms; Mice; Models, Chemical; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1999 |
Circumvention of breast cancer resistance protein (BCRP)-mediated resistance to camptothecins in vitro using non-substrate drugs or the BCRP inhibitor GF120918.
Topics: Acridines; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Camptothecin; Cell Survival; Drug Interactions; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Isoquinolines; Neoplasm Proteins; Tetrahydroisoquinolines; Tumor Cells, Cultured | 2001 |
Induction of breast cancer resistance protein by the camptothecin derivative DX-8951f is associated with minor reduction of antitumour activity.
Topics: Acridines; Animals; Antigens, CD; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Camptothecin; Cell Division; DNA Topoisomerases, Type I; Drug Resistance, Neoplasm; Female; Humans; Immunoenzyme Techniques; Isoquinolines; Membrane Glycoproteins; Mice; Mice, Nude; Mutation; Neoplasm Proteins; Neoplasms, Experimental; Ovarian Neoplasms; Tetrahydroisoquinolines; Tetraspanin 29; Tetrazolium Salts; Thiazoles; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 2002 |
C421 allele-specific ABCG2 gene amplification confers resistance to the antitumor triazoloacridone C-1305 in human lung cancer cells.
Topics: Acridines; Aminoacridines; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Amplification; Gene Expression Regulation, Neoplastic; Heterozygote; Humans; Indoles; Irinotecan; Mitoxantrone; Neoplasm Proteins; RNA, Messenger; Triazoles | 2007 |
Chemosensitivity determinants of irinotecan hydrochloride in hepatocellular carcinoma cell lines.
Topics: Acridines; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Camptothecin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Flavanones; Gene Expression Regulation, Neoplastic; Glucuronosyltransferase; Humans; Inhibitory Concentration 50; Irinotecan; Liver Neoplasms; Neoplasm Proteins; RNA, Messenger; Tetrahydroisoquinolines; Transfection | 2008 |
G-quadruplex ligand RHPS4 potentiates the antitumor activity of camptothecins in preclinical models of solid tumors.
Topics: Acridines; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Drug Synergism; Female; G-Quadruplexes; Humans; Immunohistochemistry; Ligands; Male; Mice; Mice, Nude; Neoplasms, Experimental; Xenograft Model Antitumor Assays | 2008 |
Decreased urinary secretion of belotecan in folic acid-induced acute renal failure rats due to down-regulation of Oat1 and Bcrp.
Topics: Acridines; Acute Kidney Injury; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Calcium Channel Blockers; Camptothecin; Down-Regulation; Folic Acid; Glomerular Filtration Rate; Indicators and Reagents; Kidney; Male; Organic Anion Transport Protein 1; p-Aminohippuric Acid; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines; Verapamil; Vitamin B Complex | 2009 |
The acridone derivative MBLI-87 sensitizes breast cancer resistance protein-expressing xenografts to irinotecan.
Topics: Acridines; Acridones; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Breast Neoplasms; Camptothecin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; HEK293 Cells; Humans; Irinotecan; Mice; Mice, SCID; Neoplasm Proteins; Neoplasm Transplantation; Transplantation, Heterologous | 2011 |
DNA damage persistence as determinant of tumor sensitivity to the combination of Topo I inhibitors and telomere-targeting agents.
Topics: Acridines; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Cell Cycle; Cell Survival; Cells, Cultured; Colonic Neoplasms; DNA Damage; Drug Synergism; G-Quadruplexes; HCT116 Cells; HT29 Cells; Humans; Irinotecan; Male; Mice; Mice, Nude; Telomere; Topoisomerase I Inhibitors; Treatment Outcome; Xenograft Model Antitumor Assays | 2011 |
Pharmacokinetic modeling to assess factors affecting the oral bioavailability of the lactone and carboxylate forms of the lipophilic camptothecin analogue AR-67 in rats.
Topics: Acridines; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Camptothecin; Carboxylic Acids; Female; Lactones; Models, Biological; Rats; Rats, Sprague-Dawley; Tetrahydroisoquinolines; Topoisomerase I Inhibitors | 2012 |
Abcc4 together with abcb1 and abcg2 form a robust cooperative drug efflux system that restricts the brain entry of camptothecin analogues.
Topics: Acridines; Administration, Intravenous; Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Camptothecin; Chromatography, High Pressure Liquid; Irinotecan; Mice; Mice, Knockout; Multidrug Resistance-Associated Proteins; Tetrahydroisoquinolines; Topotecan | 2013 |
Modulation of UDP-glucuronidation by acridinone antitumor agents C-1305 and C-1311 in HepG2 and HT29 cell lines, despite slight impact in noncellular systems.
Topics: Acridines; Aminoacridines; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Glucuronides; Glucuronosyltransferase; Hep G2 Cells; HT29 Cells; Humans; Irinotecan; Isoenzymes; Microsomes, Liver; Triazoles | 2018 |