Page last updated: 2024-08-22

camptothecin and 9-methoxycamptothecin

camptothecin has been researched along with 9-methoxycamptothecin in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19902 (10.00)18.7374
1990's0 (0.00)18.2507
2000's7 (35.00)29.6817
2010's10 (50.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Nicholas, AW; Wall, ME; Wani, MC1
Lindley, JT; Ronman, PE; Wall, ME; Wani, MC1
Jiang, C; Jin, W; Li, M; Lou, L; Tang, W; You, T; Zheng, C1
Dong, MJ; Li, JJ; Lin, XT; Liu, ZF; Wang, GL; Yang, SY; Zhang, Q; Zhao, K1
Fan, B; Li, S; Liu, Y; Shao, C; Wang, Y; Zheng, J1
Ji, Y; Jing, L; Shao, C; Wang, Y; Zheng, J1
DellaPenna, D; Jones, AD; Salim, V1
Andriantsiferana, R; Cao, S; Kingston, DG; Mamisoa, A; Miller, JS; Norris, A; Radwan, MM; Rakotonandrasana, S; Rasamison, VE; Ratovoson, F1
Eng, WK; Hecht, SM; Hoch, JM; Johnson, RK; Kingston, DG; Ma, J; Mattern, MR; Newman, DJ; Zhou, BN1
Fulzele, DP; Pol, BB; Satdive, RK1
Amna, T; Anand, R; Bhat, BA; Dhar, KL; Gupta, VK; Handa, G; Puri, SC; Qazi, GN; Verma, N1
Fulzele, DP; Satdive, RK1
Kusari, S; Spiteller, M; Zühlke, S1
Mohana Kumar, P; Priti, V; Ramesha, BT; Ravikanth, G; Shweta, S; Spiteller, M; Uma Shaanker, R; Vasudeva, R; Zuehlke, S1
Chayamarit, K; Chuanasa, T; Denduangboripant, J; Saito, K; Sukrong, S; Viraporn, V; Yamazaki, M1
Bhat, V; Cooks, RG; Ifa, DR; Naik, HR; Pradeep, T; Srimany, A1
Ao, M; Wang, H; Wu, J; Yu, L1
Gopalakrishnan, R; Shankar, B1
Ao, M; Bai, Y; Liu, W; Wang, H; Yu, L; Zhu, Y1
Bai, X; Liu, J; Sun, Y; Wang, C; Wei, Y; Zhang, N1

Other Studies

20 other study(ies) available for camptothecin and 9-methoxycamptothecin

ArticleYear
Plant antitumor agents. 23. Synthesis and antileukemic activity of camptothecin analogues.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:11

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Leukemia L1210; Solubility; Structure-Activity Relationship

1986
Plant antitumor agents. 18. Synthesis and biological activity of camptothecin analogues.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:5

    Topics: Animals; Camptothecin; Cells, Cultured; Chemical Phenomena; Chemistry; Leukemia P388; Mice

1980
7-Cycloalkylcamptothecin derivatives: Preparation and biological evaluation.
    Bioorganic & medicinal chemistry letters, 2009, Aug-01, Volume: 19, Issue:15

    Topics: Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Chemistry, Pharmaceutical; Colorectal Neoplasms; Drug Design; Drug Screening Assays, Antitumor; HL-60 Cells; Humans; Hydrolysis; Inhibitory Concentration 50; Irinotecan; Models, Chemical; Rhodamines; Structure-Activity Relationship; Topotecan

2009
Simple automated radiosynthesis of 10-[11C]methoxy-20(S)-camptothecin and biodistribution in normal mice.
    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, 2012, Volume: 70, Issue:10

    Topics: Animals; Automation; Camptothecin; Intestinal Mucosa; Kidney; Liver; Mice; Mice, Inbred ICR; Positron-Emission Tomography; Tissue Distribution

2012
A simple HPLC method with fluorescence detection for simultaneous determination of 10-methoxycamptothecin and its metabolite 10-hydroxycamptothecin in rat liver tissue.
    Drug research, 2015, Volume: 65, Issue:3

    Topics: Animals; Calibration; Camptothecin; Chromatography, High Pressure Liquid; Fluorescence; Limit of Detection; Liver; Male; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Fluorescence; Tissue Distribution

2015
Pharmacokinetics and tissue distribution study of 10-methoxycamptothecin in rats following intragastric administration.
    Journal of pharmaceutical and biomedical analysis, 2018, Feb-05, Volume: 149

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Area Under Curve; Biological Availability; Camptothecin; Chromatography, High Pressure Liquid; Liquid-Liquid Extraction; Male; Rats; Rats, Wistar; Tandem Mass Spectrometry; Time Factors; Tissue Distribution

2018
Camptotheca acuminata 10-hydroxycamptothecin O-methyltransferase: an alkaloid biosynthetic enzyme co-opted from flavonoid metabolism.
    The Plant journal : for cell and molecular biology, 2018, Volume: 95, Issue:1

    Topics: Alkaloids; Camptotheca; Camptothecin; Chromatography, High Pressure Liquid; Flavonoids; Metabolic Networks and Pathways; Methyltransferases; Phylogeny; Plant Proteins; Transcriptome

2018
Cytotoxic and other compounds from Didymochlaena truncatula from the Madagascar rain forest.
    Journal of natural products, 2006, Volume: 69, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Dryopteridaceae; Female; Furans; Humans; Lignans; Madagascar; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Plant Roots; Plants, Medicinal; Tumor Cells, Cultured

2006
Use of COMPARE analysis to discover new natural product drugs: isolation of camptothecin and 9-methoxycamptothecin from a new source.
    Journal of natural products, 2000, Volume: 63, Issue:9

    Topics: Algorithms; Antineoplastic Agents, Phytogenic; Camptothecin; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Spectrum Analysis; Topoisomerase I Inhibitors

2000
Growth and production of camptothecin by cell suspension cultures of Nothapodytes foetida.
    Planta medica, 2001, Volume: 67, Issue:2

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Camptothecin; Cells, Cultured; Molecular Structure; Plant Stems; Plants, Medicinal

2001
Separation of 9-methoxycamptothecin and camptothecin from Nothapodytes foetida by semipreparative HPLC.
    Journal of chromatographic science, 2005, Volume: 43, Issue:7

    Topics: Camptothecin; Chromatography, High Pressure Liquid; Chromatography, Liquid; Magnoliopsida; Mass Spectrometry

2005
Distribution of anticancer drug camptothecin in Nothapodytes foetida.
    Fitoterapia, 2005, Volume: 76, Issue:7-8

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Chromatography, High Pressure Liquid; Magnoliopsida; Plant Structures; Seeds

2005
An endophytic fungus from Camptotheca acuminata that produces camptothecin and analogues.
    Journal of natural products, 2009, Volume: 72, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Camptotheca; Camptothecin; Fusarium; Molecular Structure; Structure-Activity Relationship

2009
Endophytic fungal strains of Fusarium solani, from Apodytes dimidiata E. Mey. ex Arn (Icacinaceae) produce camptothecin, 10-hydroxycamptothecin and 9-methoxycamptothecin.
    Phytochemistry, 2010, Volume: 71, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Base Sequence; Camptothecin; DNA, Ribosomal; Fusarium; Magnoliopsida; Mycorrhizae; Trees

2010
Correlation of camptothecin-producing ability and phylogenetic relationship in the genus Ophiorrhiza.
    Planta medica, 2011, Volume: 77, Issue:7

    Topics: Amino Acid Sequence; Base Sequence; Camptothecin; Chloroplasts; DNA Topoisomerases, Type I; Genetic Variation; Humans; Molecular Sequence Data; Phylogeny; Plant Proteins; Rubiaceae; Sequence Alignment; Species Specificity; Thailand

2011
Direct analysis of camptothecin from Nothapodytes nimmoniana by desorption electrospray ionization mass spectrometry (DESI-MS).
    The Analyst, 2011, Aug-07, Volume: 136, Issue:15

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Magnoliopsida; Plant Bark; Plant Leaves; Plant Stems; Spectrometry, Mass, Electrospray Ionization

2011
TNFα and Fas/FasL pathways are involved in 9-Methoxycamptothecin-induced apoptosis in cancer cells with oxidative stress and G2/M cell cycle arrest.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 55

    Topics: Apoptosis; Base Sequence; Camptothecin; Cell Division; Cell Line, Tumor; DNA Primers; Fas Ligand Protein; fas Receptor; G2 Phase; Humans; Oxidative Stress; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Tumor Necrosis Factor-alpha

2013
Multiple shoot cultures of Ophiorrhiza rugosa var. decumbens Deb and Mondal--a viable renewable source for the continuous production of bioactive Camptotheca alkaloids apart from stems of the parent plant of Nothapodytes foetida (Wight) Sleumer.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2014, Feb-15, Volume: 21, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Camptotheca; Camptothecin; Humans; Jurkat Cells; Magnoliopsida; MCF-7 Cells; Neoplasms; Phytotherapy; Plant Extracts; Plant Shoots; Plant Somatic Embryogenesis Techniques; Plant Stems; Rubiaceae; U937 Cells

2014
Topoisomerases inhibitory activities and DNA binding properties of 9-methoxycamptothecin from Nothapodytes nimmoniana (J. Graham) Mabberly.
    Natural product research, 2019, Volume: 33, Issue:5

    Topics: Camptothecin; Circular Dichroism; DNA; Magnoliopsida; Molecular Docking Simulation; Topoisomerase I Inhibitors

2019
The biosynthesis of camptothecin derivatives by
    Natural product research, 2021, Volume: 35, Issue:14

    Topics: Camptotheca; Camptothecin; Hydrogen-Ion Concentration; Plant Roots; Seedlings

2021