camptothecin has been researched along with 7-ethyl-7-hydroxy-10h-1,3-dioxolo(4,5-g)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-8,11(7h,12h)-dione in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (44.44) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Nicholas, AW; Wall, ME; Wani, MC | 1 |
| Burke, TG; Mi, Z | 1 |
| Besterman, JM; Leitner, P; Manikumar, G; Moore, L; Nicholas, AW; Tele, C; Truesdale, A; Wall, ME; Wani, MC | 1 |
| Del Rio, M; Gongora, C; Jin, C; Lam, H; Li, F; Ling, X; Wani, M; Welch, J; Westover, D | 1 |
| Ji, L; Jiang, G; Liu, R; Liu, Z; Ma, Q; Yang, Y; Yang, Z; Zhao, H | 1 |
| Li, F; Li, Q; Weng, Q; Xia, L; Zhang, X; Zheng, Y; Zhou, L | 1 |
| Gao, H; Gao, M; Jiang, G; Lin, X; Su, Q; Tong, J; Yang, Z; Zhang, A; Zhang, X | 1 |
| Guan, H; Jiang, T; Liu, J; Liu, X; Wang, X; Wu, G; Yin, R; Yu, M; Yu, R; Zhang, Y | 1 |
| Feng, K; Jiang, T; Lv, Z; Yu, M; Zhang, J; Zhang, Y | 1 |
9 other study(ies) available for camptothecin and 7-ethyl-7-hydroxy-10h-1,3-dioxolo(4,5-g)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-8,11(7h,12h)-dione
| Article | Year |
|---|---|
Plant antitumor agents. 23. Synthesis and antileukemic activity of camptothecin analogues.
Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Leukemia L1210; Solubility; Structure-Activity Relationship | 1986 |
The structural basis of camptothecin interactions with human serum albumin: impact on drug stability.
Topics: Camptothecin; Carboxylic Acids; Chromatography, High Pressure Liquid; Half-Life; Irinotecan; Kinetics; Lactones; Molecular Structure; Serum Albumin; Spectrometry, Fluorescence; Structure-Activity Relationship; Topotecan | 1994 |
Plant antitumor agents. 30. Synthesis and structure activity of novel camptothecin analogs.
Topics: Animals; Antineoplastic Agents; Camptothecin; Female; Humans; Leukemia L1210; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred DBA; Molecular Conformation; Molecular Structure; Plants, Medicinal; Stereoisomerism; Structure-Activity Relationship; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 1993 |
FL118, a novel camptothecin derivative, is insensitive to ABCG2 expression and shows improved efficacy in comparison with irinotecan in colon and lung cancer models with ABCG2-induced resistance.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Benzodioxoles; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Colorectal Neoplasms; Disease Progression; Drug Resistance, Neoplasm; Female; Gene Silencing; Humans; Indolizines; Irinotecan; Lung Neoplasms; Mice, SCID; Neoplasm Proteins; Topoisomerase Inhibitors; Treatment Outcome; Xenograft Model Antitumor Assays | 2015 |
FL118, a novel camptothecin analogue, suppressed migration and invasion of human breast cancer cells by inhibiting epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway.
Topics: Benzodioxoles; beta Catenin; Breast Neoplasms; Cadherins; Camptothecin; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclin D; Epithelial-Mesenchymal Transition; Female; Humans; Indolizines; Inhibitor of Apoptosis Proteins; Neoplasm Invasiveness; Survivin; Vimentin; Wnt Signaling Pathway | 2018 |
In vitro evaluation of FL118 and 9-Q20 cytotoxicity and cellular uptake in 2D and 3D different cell models.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Benzodioxoles; Biological Transport; Camptothecin; Cell Proliferation; HCT116 Cells; Hep G2 Cells; Humans; In Vitro Techniques; Indolizines; Neoplasms | 2019 |
FL118 inhibits viability and induces apoptosis of colorectal cancer cells via inactivating the CIP2A/PP2A axis.
Topics: Animals; Apoptosis; Autoantigens; Benzodioxoles; Camptothecin; Cell Line, Tumor; Cell Proliferation; Cell Survival; China; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Indolizines; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Protein Phosphatase 2; Proto-Oncogene Proteins c-akt; Signal Transduction; Xenograft Model Antitumor Assays | 2019 |
Self-assembling nanoparticles of dually hydrophobic prodrugs constructed from camptothecin analogue for cancer therapy.
Topics: Animals; Benzodioxoles; Camptothecin; Chromones; Disulfides; Drug Stability; Humans; Hydrophobic and Hydrophilic Interactions; Indolizines; Lipids; Nanomedicine; Nanoparticles; Neoplasms; Prodrugs | 2020 |
Simultaneous determination of FL118 and W34 in rat Blood by LC-MS/MS: Application to pharmacokinetic studies.
Topics: Animals; Benzodioxoles; Camptothecin; Chromatography, Liquid; Indolizines; Limit of Detection; Linear Models; Male; Rats; Rats, Wistar; Reproducibility of Results; Tandem Mass Spectrometry | 2020 |