calpain inhibitor 2 has been researched along with leupeptins in 28 studies
| Studies (calpain inhibitor 2) | Trials (calpain inhibitor 2) | Recent Studies (post-2010) (calpain inhibitor 2) | Studies (leupeptins) | Trials (leupeptins) | Recent Studies (post-2010) (leupeptins) |
|---|---|---|---|---|---|
| 68 | 0 | 13 | 3,891 | 4 | 1,106 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (57.14) | 18.2507 |
| 2000's | 9 (32.14) | 29.6817 |
| 2010's | 3 (10.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bar-Nun, S; Inoue, S; Roitelman, J; Simoni, RD | 1 |
| Goldberg, AL; Jensen, TJ; Loo, MA; Pind, S; Riordan, JR; Williams, DB | 1 |
| Liu, L; Wang, M; Zimmerman, UJ | 1 |
| Banik, N; Figueiredo-Pereira, ME; Wilk, S | 1 |
| Inoue, S; Schimke, RT; Sharma, RC; Simoni, RD | 1 |
| Bennett, RG; Duckworth, WC; Hamel, FG; Harmon, KS | 1 |
| Bloemendal, H; Broers, JL; Gerards, WL; Henfling, ME; Machiels, BM; Ramaekers, FC; Schutte, B | 1 |
| DiDiodato, G; Sharom, FJ | 1 |
| Chang, YC; Heintz, NH; Illenye, S; Magae, J; Mitsui, Y; Omura, S; Tanaka, K; Tejima, T | 1 |
| Anyane-Yeboa, K; Chan, SO; Chiu, FC; Ko, L; Runko, E | 1 |
| Beppu, M; Ikebe, T; Jimi, E; Shinohara, M; Shirasuna, K; Takeuchi, H | 1 |
| Darzynkiewicz, Z; Deptala, A; Mikulski, SM; Viera, A | 1 |
| Beyer, EC; Green, K; Laing, JG; Saffitz, JE; Tadros, PN | 1 |
| Conconi, M; Djavadi-Ohaniance, L; Friguet, B; Hendil, KB; Uerkvitz, W | 1 |
| Droin, N; Eymin, B; Haugg, M; Munsch, B; Solary, E; Sordet, O; Van de Craen, M; Vandenabeele, P | 1 |
| Kaibuchi, K; Kanai-Azuma, M; Taya, S; Wood, SA; Yamamoto, T | 1 |
| Bohrn, E; Herceg, Z; Wang, ZQ; Wesierska-Gadek, J; Wurzer, G | 1 |
| An, WG; Blagosklonny, MV; Hwang, SG; Trepel, JB | 1 |
| Avner, R; Doolman, R; Harats, D; Ravid, T; Roitelman, J | 1 |
| Drahushuk, KM; Guo, X; Higgins, D; Horbinski, C; Kaplan, PL; Kim, IJ; Lein, P; Lin, Y; Wang, T | 1 |
| Emi, Y; Ikushiro, S; Iyanagi, T; Omura, S | 1 |
| Kim, JH; Mullin, CA | 1 |
| Brustis, JJ; Cottin, P; Dargelos, E; Dedieu, S; Grise, F; Mazères, G; Poussard, S | 1 |
| Chau, GY; Chau, YP; Chien, CL; Don, MJ; Kung, HN; Lu, KS | 1 |
| Aggeli, IK; Beis, I; Gaitanaki, C | 1 |
| Abrenica, B; Cook, T; Gilchrist, JS; Pierce, GN; Rashidkhani, B | 1 |
| Fujita, H; Kato, T; Kitagawa, S; Takahashi, T; Watanabe, N | 1 |
| Ali, MA; Fan, X; Holt, A; Schulz, R; Stepanko, A | 1 |
28 other study(ies) available for calpain inhibitor 2 and leupeptins
| Article | Year |
|---|---|
Inhibition of degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase in vivo by cysteine protease inhibitors.
Topics: Animals; beta-Galactosidase; Calcium; Cell Line; Chloroquine; Cysteine Proteinase Inhibitors; Egtazic Acid; Hydroxymethylglutaryl CoA Reductases; Kinetics; Leupeptins; Oligopeptides; Recombinant Fusion Proteins; Transfection | 1991 |
Multiple proteolytic systems, including the proteasome, contribute to CFTR processing.
Topics: Acetylcysteine; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; CHO Cells; Cricetinae; Cysteine Endopeptidases; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endopeptidases; Endoplasmic Reticulum; Humans; Leupeptins; Multienzyme Complexes; Oligopeptides; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Ubiquitins | 1995 |
Inhibition of secretion from isolated rat alveolar epithelial type II cells by the cell permeant calpain inhibitor II (N-acetyl-leucyl-leucyl-methioninal).
Topics: Amino Acid Sequence; Animals; Calcium; Calpain; Cell Membrane Permeability; Epithelial Cells; Epithelium; In Vitro Techniques; Leupeptins; Molecular Sequence Data; Oligopeptides; Phosphatidylcholines; Protease Inhibitors; Pulmonary Alveoli; Rats | 1995 |
Comparison of the effect of calpain inhibitors on two extralysosomal proteinases: the multicatalytic proteinase complex and m-calpain.
Topics: Amino Acid Sequence; Animals; Calpain; Cattle; Cysteine Endopeptidases; Dipeptides; Kinetics; Leupeptins; Molecular Sequence Data; Multienzyme Complexes; Oligopeptides; Pituitary Gland; Protease Inhibitors; Proteasome Endopeptidase Complex; Substrate Specificity | 1994 |
Cellular detoxification of tripeptidyl aldehydes by an aldo-keto reductase.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Animals; Cells, Cultured; CHO Cells; Cricetinae; Cytokinins; Drug Resistance; Humans; Leupeptins; Molecular Sequence Data; Oligopeptides; Protease Inhibitors | 1993 |
Insulin inhibition of proteasome activity in intact cells.
Topics: Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Hydrolysis; Insulin; Leupeptins; Multienzyme Complexes; Oligopeptides; Proteasome Endopeptidase Complex; Tumor Cells, Cultured | 1997 |
Detailed analysis of cell cycle kinetics upon proteasome inhibition.
Topics: Animals; Bromodeoxyuridine; Calpain; Cell Cycle; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Glycoproteins; Humans; Kinetics; Leupeptins; Microscopy, Phase-Contrast; Multienzyme Complexes; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Tumor Cells, Cultured | 1997 |
Interaction of combinations of drugs, chemosensitizers, and peptides with the P-glycoprotein multidrug transporter.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Cell Membrane; Colchicine; Cyclosporine; Drug Interactions; Drug Resistance, Multiple; Leupeptins; Oligopeptides; Peptides; Reserpine; Valinomycin; Vinblastine | 1997 |
Transcriptional squelching by ectopic expression of E2F-1 and p53 is alleviated by proteasome inhibitors MG-132 and lactacystin.
Topics: Acetylcysteine; Animals; beta-Galactosidase; Blotting, Northern; Carrier Proteins; Cell Cycle Proteins; CHO Cells; Cricetinae; Cycloheximide; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; E2F Transcription Factors; E2F1 Transcription Factor; Leupeptins; Oligopeptides; Protein Synthesis Inhibitors; Retinoblastoma-Binding Protein 1; RNA, Messenger; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Suppressor Protein p53; Ubiquitins | 1997 |
Calcium ionophore-induced degradation of neurofilament and cell death in MSN neuroblastoma cells.
Topics: Calcimycin; Calpain; Carrier Proteins; Cell Death; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Humans; Intermediate Filament Proteins; Leupeptins; Nerve Tissue Proteins; Neuroblastoma; Neurofibrils; Oligopeptides; Tumor Cells, Cultured | 1998 |
Involvement of proteasomes in migration and matrix metalloproteinase-9 production of oral squamous cell carcinoma.
Topics: Carcinoma, Squamous Cell; Collagenases; Cysteine Proteinase Inhibitors; Gelatinases; Humans; Leupeptins; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Mouth Neoplasms; Neoplasm Invasiveness; Neoplasm Proteins; NF-kappa B; Oligopeptides; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1998 |
Enhanced in vitro cytotoxicity and cytostasis of the combination of onconase with a proteasome inhibitor.
Topics: Antineoplastic Agents; Clone Cells; Colony-Forming Units Assay; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Egg Proteins; Flow Cytometry; Formazans; Humans; Leupeptins; Multienzyme Complexes; Oligopeptides; Proteasome Endopeptidase Complex; Ribonucleases; Tetrazolium Salts; Toxicity Tests; Tumor Cells, Cultured | 1998 |
Proteolysis of connexin43-containing gap junctions in normal and heat-stressed cardiac myocytes.
Topics: Acetylcysteine; Ammonium Chloride; Animals; Cells, Cultured; Chloroquine; Connexin 43; Cysteine Proteinase Inhibitors; Fluorescent Antibody Technique; Gap Junctions; Hot Temperature; HSP70 Heat-Shock Proteins; Immunoblotting; Leucine; Leupeptins; Lysosomes; Microscopy, Electron; Myocardium; Oligopeptides; Precipitin Tests; Protease Inhibitors; Rats | 1998 |
Conformational changes in the 20S proteasome upon macromolecular ligand binding analyzed with monoclonal antibodies.
Topics: Animals; Antibodies, Monoclonal; Antibody Affinity; Binding Sites, Antibody; Caseins; Crystallins; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme-Linked Immunosorbent Assay; Glycoproteins; HSP90 Heat-Shock Proteins; Humans; Leupeptins; Ligands; Multienzyme Complexes; Muscle Proteins; Oligopeptides; Proteasome Endopeptidase Complex; Protein Conformation; Proteins | 1999 |
Caspase-induced proteolysis of the cyclin-dependent kinase inhibitor p27Kip1 mediates its anti-apoptotic activity.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Base Sequence; Calpain; Caspase 3; Caspase 6; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; CDC2-CDC28 Kinases; Cell Cycle Proteins; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; Cysteine Proteinase Inhibitors; Etoposide; Humans; Leukemia; Leupeptins; Microtubule-Associated Proteins; Molecular Sequence Data; Mutation; Nucleic Acid Synthesis Inhibitors; Oligopeptides; Protein Serine-Threonine Kinases; Thimerosal; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins | 1999 |
The deubiquitinating enzyme Fam interacts with and stabilizes beta-catenin.
Topics: Animals; beta Catenin; Binding Sites; Cadherins; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Cytoskeletal Proteins; Dogs; Endopeptidases; Kinesins; Kinetics; L Cells; Leupeptins; Mice; Multienzyme Complexes; Myosins; Oligopeptides; Proteasome Endopeptidase Complex; ras Proteins; Recombinant Fusion Proteins; Signal Transduction; Trans-Activators; Transfection; Ubiquitin Thiolesterase; Ubiquitins | 1999 |
Differential susceptibility of normal and PARP knock-out mouse fibroblasts to proteasome inhibitors.
Topics: Acetylcysteine; Animals; Cell Line; Cell Nucleus; Cell Survival; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Fibroblasts; Fluorescent Dyes; Humans; Immunoblotting; Indoles; Leupeptins; Mice; Mice, Knockout; Microscopy, Fluorescence; Multienzyme Complexes; Oligopeptides; Phenotype; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proteasome Endopeptidase Complex; Proteins; Time Factors; Tumor Suppressor Protein p53 | 2000 |
Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition.
Topics: Acetylcysteine; Acrylates; Amino Acid Chloromethyl Ketones; Apoptosis; Boronic Acids; Bortezomib; Calpain; Cathepsins; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cysteine Endopeptidases; Drug Synergism; Genes, p53; Humans; Jurkat Cells; Leupeptins; Multienzyme Complexes; Neoplasm Proteins; Neoplasms; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Tumor Cells, Cultured; Tumor Suppressor Protein p53; U937 Cells | 2000 |
The ubiquitin-proteasome pathway mediates the regulated degradation of mammalian 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Topics: Animals; beta-Galactosidase; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Cholesterol; Cricetinae; Cycloheximide; Cysteine Proteinase Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Humans; Hydroxycholesterols; Hydroxymethylglutaryl CoA Reductases; Leupeptins; Lovastatin; Oligopeptides; Peptide Hydrolases; Precipitin Tests; Proteasome Endopeptidase Complex; Recombinant Fusion Proteins; Tricarboxylic Acids; Ubiquitins | 2000 |
Dendritic growth induced by BMP-7 requires Smad1 and proteasome activity.
Topics: Acetylcysteine; Animals; Bone Morphogenetic Protein 7; Bone Morphogenetic Proteins; Cell Nucleus; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dendrites; DNA-Binding Proteins; Gene Expression; Leupeptins; Multienzyme Complexes; Neurons; Neuroprotective Agents; Oligopeptides; Proteasome Endopeptidase Complex; Rats; Rats, Sprague-Dawley; Smad Proteins; Smad1 Protein; Superior Cervical Ganglion; Trans-Activators; Transcriptional Activation; Transfection; Transforming Growth Factor beta | 2001 |
Accelerated degradation of mislocalized UDP-glucuronosyltransferase family 1 (UGT1) proteins in Gunn rat hepatocytes.
Topics: Acetylcysteine; Animals; Cells, Cultured; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Glucuronosyltransferase; Glycoproteins; Half-Life; Hepatocytes; Leupeptins; Male; Monosaccharide Transport Proteins; Multienzyme Complexes; Mutation; Oligopeptides; Proteasome Endopeptidase Complex; Rats; Rats, Gunn; Rats, Wistar; RNA, Messenger; Subcellular Fractions | 2002 |
Impact of cysteine proteinase inhibition in midgut fluid and oral secretion on fecundity and pollen consumption of western corn rootworm (Diabrotica virgifera virgifera).
Topics: Animals; Coleoptera; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Digestive System; Eating; Female; Fertility; Leucine; Leupeptins; Male; Oligopeptides; Pollen; Zea mays | 2003 |
Myoblast migration is regulated by calpain through its involvement in cell attachment and cytoskeletal organization.
Topics: Animals; Calcium-Binding Proteins; Calpain; Cell Adhesion; Cell Fusion; Cell Line; Cell Movement; Clone Cells; Cysteine Proteinase Inhibitors; Cytoskeleton; Dipeptides; Dose-Response Relationship, Drug; Glucosidases; Intracellular Signaling Peptides and Proteins; Leupeptins; Membrane Proteins; Mice; Muscle Fibers, Skeletal; Myoblasts; Myristoylated Alanine-Rich C Kinase Substrate; Oligopeptides; Phosphoproteins; Stress Fibers | 2004 |
Involvement of NO/cGMP signaling in the apoptotic and anti-angiogenic effects of beta-lapachone on endothelial cells in vitro.
Topics: Angiogenesis Inhibitors; Apoptosis; Arginine; Calcium; Calpain; Caspases; Cell Line; Cell Survival; Chelating Agents; Cyclic GMP; Dose-Response Relationship, Drug; Egtazic Acid; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors; Humans; Leupeptins; Membrane Potential, Mitochondrial; Naphthoquinones; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Oligopeptides; Signal Transduction; Time Factors | 2007 |
Oxidative stress and calpain inhibition induce alpha B-crystallin phosphorylation via p38-MAPK and calcium signalling pathways in H9c2 cells.
Topics: alpha-Crystallin B Chain; Animals; Apoptosis; Calcium Signaling; Calpain; Caspase 3; Cell Line; Cell Nucleus; Cytochromes c; Egtazic Acid; Hydrogen Peroxide; Leupeptins; Myocytes, Cardiac; Oligopeptides; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phosphoserine; Poly(ADP-ribose) Polymerases; Protein Transport; Rats; Ribosomal Protein S6 Kinases, 90-kDa; Time Factors; Tubulin | 2008 |
Extensive autolytic fragmentation of membranous versus cytosolic calpain following myocardial ischemia-reperfusion.
Topics: Animals; Autolysis; Blotting, Western; Calpain; Cell Fractionation; Cytosol; Disease Models, Animal; Dogs; Electrophoresis, Polyacrylamide Gel; Intracellular Membranes; Leupeptins; Male; Muscle, Skeletal; Myocardial Reperfusion Injury; Myocardium; Oligopeptides; Rabbits; Rats; Rats, Sprague-Dawley | 2010 |
Stimulation of human formyl peptide receptors by calpain inhibitors: homology modeling of receptors and ligand docking simulation.
Topics: Acrylates; Base Sequence; Binding Sites; Calcium Signaling; Computer Simulation; Cysteine Proteinase Inhibitors; DNA Primers; Glycoproteins; HEK293 Cells; Humans; Leupeptins; Ligands; Models, Molecular; N-Formylmethionine Leucyl-Phenylalanine; Oligopeptides; Receptors, Formyl Peptide; Receptors, Lipoxin; Recombinant Proteins; Structural Homology, Protein | 2011 |
Calpain inhibitors exhibit matrix metalloproteinase-2 inhibitory activity.
Topics: Acrylates; Calpain; Catalysis; Cell Line; Cysteine Proteinase Inhibitors; Dipeptides; Gelatin; Humans; Inhibitory Concentration 50; Leupeptins; Matrix Metalloproteinase 2; Matrix Metalloproteinase Inhibitors; Oligopeptides; Phenyl Ethers; Troponin I | 2012 |