calpain has been researched along with tetrandrine* in 1 studies
1 other study(ies) available for calpain and tetrandrine
Article | Year |
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Tetrandrine alleviates podocyte injury via calcium-dependent calpain-1 signaling blockade.
Podocytes have become a crucial target for interventions in proteinuric kidney diseases. Many studies have reported that overexpression of transient receptor potential cation channel protein 6 (TRPC6) in podocyte injury upregulates intracellular Ca. We investigated the involvement of tetrandrine in Ca. Tetrandrine decreased intracellular Ca. Tetrandrine has therapeutic potential in podocyte damage by blocking Ca Topics: Animals; Benzylisoquinolines; Calcium; Calcium Channel Blockers; Calpain; Cell Line; Disease Models, Animal; Doxorubicin; Male; Mice; Podocytes; Rats, Sprague-Dawley; Renal Insufficiency, Chronic; Signal Transduction | 2021 |