calpain has been researched along with miltefosine* in 1 studies
1 other study(ies) available for calpain and miltefosine
| Article | Year |
|---|---|
Identification and Functional Validation of a Biomarker for the Diagnosis of Miltefosine Relapse during Visceral Leishmaniasis.
Miltefosine is the only orally administrable drug for the treatment of leishmaniasis. But in recent years, a decline in its efficacy points toward the emergence of resistance to this drug. Knowledge of biomarkers for miltefosine resistance may be beneficial for proper selection of treatment regimen. Splenic aspirates were collected and parasites cultured from patients relapsed after initial cure ( Topics: Antiprotozoal Agents; Biomarkers; Biopsy, Needle; Calpain; Humans; Leishmania donovani; Leishmaniasis, Visceral; Phosphorylcholine; Real-Time Polymerase Chain Reaction; Recurrence; Spleen | 2018 |