calixarenes has been researched along with betadex* in 12 studies
2 review(s) available for calixarenes and betadex
Article | Year |
---|---|
Application of Infrared Multiple Photon Dissociation (IRMPD) Spectroscopy in Chiral Analysis.
In recent years, methods based on photodissociation in the gas phase have become powerful means in the field of chiral analysis. Among them, infrared multiple photon dissociation (IRMPD) spectroscopy is a very attractive one, since it can provide valuable spectral and structural information of chiral complexes in addition to chiral discrimination. Experimentally, the method can be fulfilled by the isolation of target diastereomeric ions in an ion trap followed by the irradiation of a tunable IR laser. Chiral analysis is performed by comparing the difference existing in the spectra of enantiomers. Combined with theoretical calculations, their structures can be further understood on the molecular scale. By now, lots of chiral molecules, including amino acids and peptides, have been studied with the method combined with theoretical calculations. This review summarizes the relative experimental results obtained, and discusses the limitation and prospects of the method. Topics: beta-Cyclodextrins; Calixarenes; Dimerization; Gases; Ions; Ligands; Mass Spectrometry; Peptides; Photochemistry; Photons; Physical Phenomena; Reproducibility of Results; Serine; Spectrophotometry, Infrared; Stereoisomerism | 2020 |
Gas-phase enantioselective reactions in noncovalent ion-molecule complexes.
Noncovalent diastereomeric ion-molecule complexes are produced in the gas phase and are ideal for the study of chiral recognition in the absence of complicating solvent and counterion effects. This review article describes the state-of-art in this field with special emphasis on the most recent mass spectrometric studies of the structure, dynamics, and reactivity of diastereomeric ion/molecule aggregates. Topics: Amides; beta-Cyclodextrins; Calixarenes; Gases; Phenylalanine; Stereoisomerism; Substrate Specificity | 2009 |
10 other study(ies) available for calixarenes and betadex
Article | Year |
---|---|
A comparison study of macrocyclic hosts functionalized reduced graphene oxide for electrochemical recognition of tadalafil.
The present work described the comparison of β-cyclodextrin (β-CD) and p-sulfonated calix[6]arene (SCX6) functionalized reduced graphene oxide (RGO) for recognition of tadalafil. In this study, tadalafil and two macrocycles (β-CD and SCX6) were selected as the guest and host molecules, respectively. The inclusion complexes of β-CD/tadalafil and SCX6/tadalafil were studied by UV spectroscopy and molecular simulation calculations, proving the higher supermolecular recognition capability of SCX6 than β-CD towards tadalafil. The β-CD@RGO and SCX6@RGO composites were prepared by a wet-chemical route. The obtained composites were characterized by Fourier transform infrared spectrometry, thermogravimetric analysis, atomic force microscopy, and zeta potential. The SCX6@RGO showed a higher electrochemical response than β-CD@RGO, which was caused by the higher recognition capability of SCX6 than β-CD. By combining the merits of SCX6 and the RGO, a sensitive electrochemical sensing platform was developed based on the SCX6@RGO nanohybrids. A linear response range of 0.1-50 μM and 50-1000 μM for tadalafil with a low detection limit of 0.045 μM (S/N=3) was obtained by using this method. The constructed sensing platform was successfully used to determine tadalafil in herbal sexual health products and spiked human serum samples, suggesting its promising analytical applications for the trace level determination of tadalafil. Topics: beta-Cyclodextrins; Biosensing Techniques; Calixarenes; Electrochemical Techniques; Graphite; Humans; Limit of Detection; Models, Molecular; Molecular Docking Simulation; Oxidation-Reduction; Oxides; Phenols; Plants, Medicinal; Sulfones; Tadalafil; Vasodilator Agents | 2017 |
β-Cyclodextrin and calix[4]arene-25,26,27,28-tetrol capped carbon dots for selective and sensitive detection of fluoride.
In this work we have designed a novel system based on carbon dots prepared from chitosan gel capped with β-cyclodextrin and calix[4]arene-25,26,27,28-tetrol for sensitive and selective detection of fluoride ions in aqueous media. Fluorescent carbon dots prepared from chitosan gel when capped with β-cyclodextrin and calix[4]arene-25,26,27,28-tetrol results in quenching of its fluorescence intensity. Introduction of F(-) ions to carbon dots capped with β-cyclodextrin and calix[4]arene-25,26,27,28-tetrol system results in enhancement and restoration of fluorescence intensity leading to detection of F(-) ion. Minimum detection limit was determined to be ∼6.6 μM. The detection is selective as with other halide ions i.e. Cl(-), Br(-) and I(-) and hydroxyl ion (OH(-)), there is observed decrease of fluorescence intensity. A possible mechanism to justify the observation is also discussed in the paper. Topics: beta-Cyclodextrins; Calixarenes; Carbon; Chitosan; Fatty Acids, Unsaturated; Fluorides; Gels; Limit of Detection; Phenols; Spectrometry, Fluorescence | 2015 |
Novel Comparative Synchronous Spectrofluorimetric Study of Benzo(a)pyrene Using Beta-Cyclodextrin and Calix(8)arene as Fluorescence Enhancers.
Successfully benzo(a)pyrene could be quantitified in environmental samples by a novel synchronous spectrofluorimetric techniques at a constant wavelength difference Δλ = 120 nm, using beta-cyclodextrin 'β-CD' and calix(8)arene as fluorescence enhancers, where a linear calibration curve was obtained in a concentration range of 900-14,400 pg mL(-1) and 18-360 pg mL(-1) and the detection limit of 380.00 pg mL(-1) and 12.08 pg mL(-1) (which is well below the maximum contaminant concentration for benzo(a)pyrene set by the Environmental Protection Agency 'EPA') using both enhancers, respectively. The method can be easily adopted for determination of benzo(a)pyrene in aqueous media including tap water, river water and complex water samples. The recoveries obtained were 85.13-113.36 % with RSD < 4 %. The proposed method was validated according to International Conference of Harmonization (ICH) guide lines and successfully applied to determine benzo(a)pyrene in pure form and in water samples including contaminated environmental water samples. All the results obtained were compared with those of a published method, where no significant difference was observed. Topics: beta-Cyclodextrins; Calixarenes; Spectrometry, Fluorescence; Temperature | 2014 |
Preparation and characterization of 4-isopropylcalix[4]arene-capped (3-(2-O-β-cyclodextrin)-2-hydroxypropoxy)-propylsilyl-appended silica particles as chiral stationary phase for high-performance liquid chromatography.
A new type of 4-isopropylcalix[4]arene-capped (3-(2-O-β-cyclodextrin)-2-hydroxypropoxy)propylsilyl-appended silica particles (IPC4CD-HPS) has been prepared by treatment of bromoacetate-substituted (3-(2-O-β-cyclodextrin)-2-hydroxypropoxy)propylsilyl-appended silica particles (BACD-HPS) with 4-isopropylcalix[4]arene oxyanions in anhydrous N-methyl-2-pyrrolidone. The bonded silica IPC4CD-HPS has been successfully used as chiral stationary phase (CSP) in high-performance liquid chromatography (HPLC) for the first time. The synthetic stationary phase was characterized by means of elemental analysis and Fourier transform infrared spectroscopy. This new CSP has a chiral selector with two anchored functional moieties: 4-isopropylcalix[4]arene and β-cyclodextrin. The chromatographic performance of IPC4CD-HPS was investigated by separation of positional isomers of several disubstituted benzenes and enantiomers of some chiral drug compounds under reversed-phase conditions. The results showed that IPC4CD-HPS had excellent selectivity for the separation of aromatic positional isomers and enantiomers of chiral compounds due to the cooperative functioning of the anchored 4-isopropylcalix[4]arenes and β-cyclodextrins. Topics: Benzene; beta-Cyclodextrins; Calixarenes; Chromatography, High Pressure Liquid; Phenols; Silicon Dioxide; Stereoisomerism | 2014 |
Large negatively charged organic host molecules as inhibitors of endonuclease enzymes.
Three large negatively charged organic host molecules; β-cyclodextrin sulphate, para-sulphonato-calix[6]arene and para-sulphonato-calix[8]arene have been shown to be effective inhibitors of endonuclease in the low micromolar range, additionally para-sulphonato-calix[8]arene is a partial inhibitor of rhDNase I. Topics: beta-Cyclodextrins; Binding Sites; Calixarenes; Deoxyribonuclease I; DNA; Endonucleases; Enzyme Inhibitors; Humans; Nanoparticles | 2014 |
Preparation and evaluation of calix[4]arene-capped beta-cyclodextrin-bonded silica particles as chiral stationary phase for high-performance liquid chromatography.
Calix[4]arene-capped [3-(2-O-beta-cyclodextrin)-2-hydroxypropoxy]propylsilyl-appended silica particles (C4CD-HPS), a new type of substituted beta-cyclodextrin-bonded chiral stationary phase (CSP) for high-performance liquid chromatography (HPLC), have been synthesized by treatment of bromoacetate-substituted [3-(2-O-beta-cyclodextrin)-2-hydroxypropoxy]propylsilyl-appended silica particles (BACD-HPS) with calix[4]arene oxyanions in anhydrous N-methyl-2-pyrrolidone. The synthetic stationary phase is characterized by means of elemental analysis. This new type of CSP has a chiral selector with two recognition sites: calix[4]arene and beta-cyclodextrin (beta-CD). The chromatographic behavior of C4CD-HPS was studied with several disubstituted benzenes and some chiral drug compounds under reversed-phase conditions. The results show that C4CD-HPS has excellent selectivity for the separation of aromatic positional isomers and enantiomers of chiral compounds due to the cooperative functioning of calix[4]arenes and beta-CDs. Topics: beta-Cyclodextrins; Calixarenes; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Phenols; Silicon Dioxide | 2008 |
Photophysics of cyclic multichromophoric systems based on beta-cyclodextrin and calix[4]arene with appended pyridin-2'-yl-1,2,3-triazole groups.
The photophysical properties of the new pyridin-2'-yl-1,2,3-triazole chromophore have been investigated. Spectroscopic experiments and molecular modelling have provided evidence for a photoinduced charge transfer occurring from the triazole group to the pyridine ring. Hepta- and tetrachromophoric systems have been synthesized by covalently linking seven or four chromophores of this kind, respectively, to a beta-cyclodextrin and a calix[4]arene. They exhibit different fluorescence spectra, decays and quantum yields. Special attention has been paid to the binding of cadmium and zinc ions and to the resulting photophysical effects which are various and very different for the grafted beta-cyclodextrin and calix[4]arene systems. Topics: Absorption; beta-Cyclodextrins; Cadmium; Calixarenes; Color; Fluorescence; Models, Molecular; Phenols; Pyridines; Spectrometry, Fluorescence; Time Factors; Triazoles | 2008 |
[Study on the interaction between p-octacarboxyphenylazocalix[8]arene and norfloxacin by fluorescence spectrometry].
In the present paper, p-octacarboxyphenylazocalix[8]arene (CPAC) was used as supramolecular probe according to a reported method. The interaction of CPAC with drug norfloxacin (NFLX) was studied by fluorescence spectrometry. The results show that CPAC can strongly quench the fluorescence of NFLX because of the complex interaction between host and guest molecules in exo-inclusion complex. The spectral changes indicated that the quenching can be considered as static quenching mode. The hydrophobic interaction between the cavity of CPAC and the quinoline ring was the main force to consolidate the exo-inclusive complex CPAC-NFLX stability. The complex constant (K) and binding ratio (n) were determined to be 6. 38 X 10(5) L x mol(-1) and 1, respectively. Further experiment found that the calf thymus DNA and CPAC can combine, leading to the release of NFLX and the enhancement of fluorescence of the reaction system. It is expected that CPAC will be used as drug carrier and releaser. Topics: Animals; beta-Cyclodextrins; Calixarenes; Cattle; DNA; Hydrogen-Ion Concentration; Molecular Structure; Norfloxacin; Spectrometry, Fluorescence; Temperature | 2007 |
[Chiral separation of dipeptides by capillary electrophoresis].
Peptides are increasingly used as pharmaceutical agents. Many small peptides are the essential compounds in biological systems. Direct chiral separation of dipeptide derivatives using 9-(2-carbazole) ethyl chloroformate (CEOC) as the derivatizing agent by capillary electrophoresis (CE) with beta-cyclodextrin (beta-CD) and sodium deoxycholate (SDC) as chiral selectors has been developed. It has been well recognized that the combination of the binary selectors can enhance the selectivity and resolution instead of either beta-CD or SDC alone. The molar ratio of the binary chiral selectors, the buffer concentration and pH of Tris-H3PO4, organic modifier were studied and optimized. Complete chiral separations for 14 dipeptide derivatives using beta-CD and SDC as binary chiral selectors were obtained. The results indicated that each pair of D/L chiral resolution was more than 3.63, and the highest resolution for Gly-Ala was 43.14. Topics: beta-Cyclodextrins; Calixarenes; Carbazoles; Deoxycholic Acid; Dipeptides; Electrophoresis, Capillary; Stereoisomerism | 2006 |
Mixed chiral stationary phase containing modified resorcinarene and beta-cyclodextrin selectors bonded to a polysiloxane for enantioselective gas chromatography.
Both a resorcinarene with pendant L-valine diamide groups (used as hydrogen-bonding selector) and a permethylated beta-cyclodextrin (used as inclusion-type selector) were chemically bonded to poly(hydromethyl)dimethylsiloxane in a one-pot reaction via Pt-catalyzed alkene hydrosilylation. This novel mixed chiral stationary phase (mixCSP) named Chirasil-Calixval-Dex resembles a combination of the known chiral stationary phases (CSPs) Chirasil-Calixval and Chirasil-Dex and it was used successfully in enantioselective gas chromatography toward a unified enantioselective GC separation system. It is demonstrated that Chirasil-Calixval-Dex retains the individual enantioselectivites of the single components. Thus the enantiomers of apolar hydrocarbons as well as polar amino acid derivatives can be separated with the mixed CSP. Topics: beta-Cyclodextrins; Calixarenes; Chromatography, Gas; Cyclodextrins; Hydrogen Bonding; Phenylalanine; Siloxanes; Stereoisomerism | 2003 |