calixarenes and 1-palmitoyl-2-oleoylphosphatidylcholine

A dual host approach for M(+)/Cl(-) co-transport has been shown to be effective in lipid bilayers consisting of POPC using fluorescence-based transport assays.

Topics: Acridines; Calixarenes; Fluorescent Dyes; Lipid Bilayers; Phosphatidylcholines; Porphyrins; Salts; Spectrometry, Fluorescence; Valinomycin

meso-Octamethyloctafluorocalixpyrrole, a simple tetrapyrrolic macrocycle, has been shown to function as both a chloride/nitrate and a chloride/bicarbonate antiport agent for lipid bilayer transmembrane anion transport. This is the first example of a synthetic macrocyclic pyrrole-based receptor capable of transmembrane bicarbonate transport.

Topics: Anions; Bicarbonates; Calixarenes; Chloride-Bicarbonate Antiporters; Lipid Bilayers; Nitrates; Phosphatidylcholines; Porphyrins; Sodium Chloride; Sulfates

Three new bis-1,2,3-triazole strapped calix[4]pyrroles have been prepared via'click' chemistry and their anion complexation and lipid bilayer transport properties studied by a combination of single crystal X-ray diffraction studies, (1)H NMR titration techniques, isothermal titration calorimetry and lipid bilayer anion transport studies in POPC vesicles. Bilayer transport efficiency for transmembrane chloride transport was found to directly depend on the length of the alkyl chain present in the bis-triazole strap.

Topics: Anions; Calixarenes; Calorimetry; Crystallography, X-Ray; Ion Transport; Lipid Bilayers; Magnetic Resonance Spectroscopy; Models, Molecular; Phosphatidylcholines; Porphyrins; Titrimetry