calix(4)arene and hexafluoroisopropanol

calix(4)arene has been researched along with hexafluoroisopropanol* in 1 studies

Other Studies

1 other study(ies) available for calix(4)arene and hexafluoroisopropanol

ArticleYear
Calix[4]arene derivatives monosubstituted at all four methylene bridges.
    The Journal of organic chemistry, 2008, Apr-04, Volume: 73, Issue:7

    The scope of the reaction of the tetrabromocalixarene derivative 2b with alcohols under solvolytic conditions in trifluoroethanol (TFE) or hexafluoroisopropanol (HFIP) was explored. The reaction proceeded readily with MeOH, EtOH, n-PrOH, ethylene glycol and i-PrOH affording preferentially the rccc isomer of the tetrasubstituted product. The methoxy derivative 6a undergoes isomerization upon attempted recrystallization from CHCl3/MeOH and its rcct and rctt forms were characterized by X-ray crystallography. Incorporation of hydroxy groups on the bridges was accomplished via solvolysis in AcOH, followed by LiAlH4 reduction of the acetoxy groups. Reaction of the tetra-(2-methylfuranyl)calixarene derivative 11 with benzyne followed by deoxygenation with Me3SiCl/NaI afforded in low yield the tetra-(4-methylnaphthyl)calix[4]arene derivative 12. Reaction of de-tert-butylated tetrabromo derivative 2a with m-xylene in HFIP followed by methylation of the crude product afforded the tetraxylyl derivative 14.

    Topics: Alcohols; Calixarenes; Crystallography, X-Ray; Methane; Models, Molecular; Molecular Structure; Phenols; Propanols; Stereoisomerism; Trifluoroethanol

2008