calix(4)arene and 10-10--dimethyl-9-9--biacridinium

calix(4)arene has been researched along with 10-10--dimethyl-9-9--biacridinium* in 1 studies

Other Studies

1 other study(ies) available for calix(4)arene and 10-10--dimethyl-9-9--biacridinium

Article	Year
Indicator displacement assays inside live cells. Angewandte Chemie (International ed. in English), 2015, Jan-12, Volume: 54, Issue:3 The macrocycle p-sulfonatocalix[4]arene (CX4) and the fluorescent dye lucigenin (LCG) form a stable host-guest complex, in which the dye fluorescence is quenched. Incubation of live V79 and CHO cells with the CX4/LCG chemosensing ensemble resulted in its spontaneous uptake. Subsequent addition of choline, acetylcholine, or protamine, which have a high affinity for CX4 and are capable of entering cells, resulted in a fluorescence switch-on response. This can be traced to the displacement of LCG from CX4 by the analytes. The results establish the principal functionality of indicator displacement assays with synthetic receptors for the detection of the uptake of bioorganic analytes by live cells. Topics: Acetylcholine; Acridines; Animals; Calixarenes; Cell Line; CHO Cells; Choline; Cricetinae; Cricetulus; Fluorescent Dyes; Microscopy, Fluorescence; Phenols; Protamines	2015

Article

Year

Indicator displacement assays inside live cells.

Angewandte Chemie (International ed. in English), 2015, Jan-12, Volume: 54, Issue:3

The macrocycle p-sulfonatocalix[4]arene (CX4) and the fluorescent dye lucigenin (LCG) form a stable host-guest complex, in which the dye fluorescence is quenched. Incubation of live V79 and CHO cells with the CX4/LCG chemosensing ensemble resulted in its spontaneous uptake. Subsequent addition of choline, acetylcholine, or protamine, which have a high affinity for CX4 and are capable of entering cells, resulted in a fluorescence switch-on response. This can be traced to the displacement of LCG from CX4 by the analytes. The results establish the principal functionality of indicator displacement assays with synthetic receptors for the detection of the uptake of bioorganic analytes by live cells.

Topics: Acetylcholine; Acridines; Animals; Calixarenes; Cell Line; CHO Cells; Choline; Cricetinae; Cricetulus; Fluorescent Dyes; Microscopy, Fluorescence; Phenols; Protamines

2015