calix(4)arene and 1-4-7-triazacyclononane

calix(4)arene has been researched along with 1-4-7-triazacyclononane* in 1 studies

Other Studies

1 other study(ies) available for calix(4)arene and 1-4-7-triazacyclononane

Article	Year
Ribonuclease Activity of an Artificial Catalyst That Combines a Ligated Cu(II) Ion and a Guanidinium Group at the Upper Rim of a cone-Calix[4]arene Platform. The Journal of organic chemistry, 2015, Jun-05, Volume: 80, Issue:11 A cone-calix[4]arene derivative, featuring a guanidinium group and a Cu(II) ion ligated to a 1,4,7-triazacyclononane (TACN) ligand at the 1,3-distal positions of the upper rim, effectively catalyzes the cleavage of 2-hydroxypropyl p-nitrophenyl phosphate (HPNP) and a number of diribonucleoside 3',5'-monophosphates (NpN'). Kinetic and potentiometric measurements support the operation of a general-base/general-acid mechanism and demonstrate that the hydroxo form of the ligated Cu(II) ion is the sole catalytically active species. Rate enhancements relative to the background hydrolysis reaction at 1 mM catalyst concentration are 6 × 10(5)-fold for HPNP and cluster around 10(7)-fold with the most favorable catalyst-NpN' combinations. Topics: Biochemical Phenomena; Calixarenes; Catalysis; Copper; Guanidine; Heterocyclic Compounds; Organometallic Compounds; Organophosphates; Phenols; Ribonucleases; Ribonucleosides	2015

Article

Year

Ribonuclease Activity of an Artificial Catalyst That Combines a Ligated Cu(II) Ion and a Guanidinium Group at the Upper Rim of a cone-Calix[4]arene Platform.

The Journal of organic chemistry, 2015, Jun-05, Volume: 80, Issue:11

A cone-calix[4]arene derivative, featuring a guanidinium group and a Cu(II) ion ligated to a 1,4,7-triazacyclononane (TACN) ligand at the 1,3-distal positions of the upper rim, effectively catalyzes the cleavage of 2-hydroxypropyl p-nitrophenyl phosphate (HPNP) and a number of diribonucleoside 3',5'-monophosphates (NpN'). Kinetic and potentiometric measurements support the operation of a general-base/general-acid mechanism and demonstrate that the hydroxo form of the ligated Cu(II) ion is the sole catalytically active species. Rate enhancements relative to the background hydrolysis reaction at 1 mM catalyst concentration are 6 × 10(5)-fold for HPNP and cluster around 10(7)-fold with the most favorable catalyst-NpN' combinations.

Topics: Biochemical Phenomena; Calixarenes; Catalysis; Copper; Guanidine; Heterocyclic Compounds; Organometallic Compounds; Organophosphates; Phenols; Ribonucleases; Ribonucleosides

2015