calcium phosphate, dibasic, anhydrous and cellulose

calcium phosphate, dibasic, anhydrous has been researched along with cellulose in 50 studies

Research

Studies (50)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (4.00)	18.7374
1990's	11 (22.00)	18.2507
2000's	16 (32.00)	29.6817
2010's	20 (40.00)	24.3611
2020's	1 (2.00)	2.80

Authors

Authors	Studies
Dwivedi, SK; Mitchell, AG; Oates, RJ	1
Baert, L; De Baets, P; Fanara, D; Remon, JP	1
Hall, MW; Thomas, EE	1
Chilamkurti, RN; Rhodes, CT; Schwartz, JB	1
Augsburger, LL; Muller, FX	1
Bohác, V; Ketolainen, J; Kubicár, L; Markovic, M; Paronen, P	1
Hoag, SW; Rippie, EG	1
Buijs, MJ; Damen, JJ; Nieuw Amerongen, AV; ten Cate, JM; van der Reijden, WA; Veerman, EC	1
Daculsi, G; Grimandi, G; Millot, F; Weiss, P	1
Ho, HO; San, YP; Sheu, MT; Tsai, T; Wu, JS	1
Doherty, P; Hailey, PA; Sekulic, SS; Wakeman, J	1
Alderborn, G; Johansson, B; Nicklasson, F	2
Picker, KM	2
Schwartz, JB; Zhang, YE	1
Harjunen, P; Korhonen, O; Nakari, J; Paronen, P; Peltonen, S; Raatikainen, P; Suihko, E; Vidgren, M	1
Bikane, F; Picker, KM	1
Lastres, JL; Malamataris, S; Nikolakakis, I; Rodriguez, EC; Torrado, JJ; Torrado, S	1
Anderson, SR; Augsburger, LL; Hoag, SW; Kuppuswamy, R	1
Martineli, AC; Pereira, JC; Tung, MS	1
Dansereau, R; Patel, H; Sakr, A; Stalcup, A	1
Lee, YS; Newton, JM; Podczeck, F; Poynter, R	1
Chern, RT; Farber, L; Hill, BT; Mancinelli, C; Rajniak, P; Stepanek, F	1
Herting, MG; Kleinebudde, P; Klose, K	1
Nkansah, P; Shao, ZJ; Sobotka, S; Wu, SJ; Yamamoto, K	1
Aburub, A; Almaya, A	1
Lalwani, AN; Parikh, JR	1
Kong, A; Leyva, N; Luner, PE; Morris, DG; Truitt, BF	1
Fukase, Y; Fukuyama, T; Ito, K; Sato, S	1
Busignies, V; Leclerc, B; Tchoreloff, P; Truchon, S	1
Kushner, J; Moore, F	1
Kraciuk, R; Sznitowska, M	1
Kushner, J	1
Klinzing, G; Zavaliangos, A	1
Dreu, R; Govedarica, B; Ilić, I; Šibanc, R; Srčič, S	1
Müllers, KC; Pinto, JF; Wahl, MA	1
Bines, E; Carmody, A; Golchert, D	1
Dinunzio, J; Hegde, S; Iyer, RM; Malick, W; Singhal, D	1
Busignies, V; Diarra, H; Mazel, V; Tchoreloff, P	1
Feng, Y; Osei-Yeboah, F; Sun, CC; Zhang, M	1
de Matas, M; Huang, Z; Reynolds, GK; Salman, AD; Yu, S	1
Kushner, J; Schlack, H	1
Bataille, B; Baylac, G; Lefèvre, P; Nofrerias, I; Ravel, P; Sharkawi, T; Soulairol, I; Tarlier, N	1
Patel, S; Sun, CC	1
Flanagan, T; Fotaki, N; Mann, J; Meehan, E; Zarmpi, P	1
Campbell, JI; Reynolds, GK; Roberts, RJ	1
Paul, S; Sun, CC	1
Burlage, R; Huang, C; Klinzing, G; Procopio, A; Ren, J; Su, Y; Yang, F; Zhu, L	1
Rantanen, J; Skelbæk-Pedersen, AL; Vilhelmsen, TK; Wallaert, V	1

Reviews

1 review(s) available for calcium phosphate, dibasic, anhydrous and cellulose

Article	Year
Biopharmaceutical aspects and implications of excipient variability in drug product performance. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2017, Volume: 111 Topics: Calcium Phosphates; Cellulose; Chemistry, Pharmaceutical; Dosage Forms; Drug Design; Excipients; Gastrointestinal Tract; Humans; Hydrogen-Ion Concentration; Lactose; Materials Testing; Molecular Conformation; Particle Size; Polymers; Porosity; Solubility; Technology, Pharmaceutical; Temperature	2017

Article

Year

Biopharmaceutical aspects and implications of excipient variability in drug product performance.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2017, Volume: 111

Topics: Calcium Phosphates; Cellulose; Chemistry, Pharmaceutical; Dosage Forms; Drug Design; Excipients; Gastrointestinal Tract; Humans; Hydrogen-Ion Concentration; Lactose; Materials Testing; Molecular Conformation; Particle Size; Polymers; Porosity; Solubility; Technology, Pharmaceutical; Temperature

2017

Other Studies

49 other study(ies) available for calcium phosphate, dibasic, anhydrous and cellulose

Article	Year
Peak offset times as an indication of stress relaxation during tableting on a rotary tablet press. The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:10 Topics: Acetaminophen; Calcium Phosphates; Cellulose; Ibuprofen; Lactose; Pressure; Tablets; Technology, Pharmaceutical	1991
Instrumentation of a gravity feed extruder and the influence of the composition of binary and ternary mixtures on the extrusion forces. The Journal of pharmacy and pharmacology, 1991, Volume: 43, Issue:11 Topics: Calcium Phosphates; Cellulose; Equipment Design; Lactose; Technology, Pharmaceutical	1991
Effect of selected dietary buffers upon utilization of concentrate- or roughage-based cattle diets: laboratory studies. Journal of animal science, 1984, Volume: 59, Issue:1 Topics: Ammonia; Animals; Bacteria; Bacterial Proteins; Bicarbonates; Buffers; Calcium Carbonate; Calcium Phosphates; Cattle; Cellulose; Dietary Fiber; Dietary Proteins; Digestion; Diphosphates; Fatty Acids, Volatile; Fermentation; Hydrogen-Ion Concentration; In Vitro Techniques; Nitrogen; Rumen; Sodium Bicarbonate; Starch	1984
Effect of addition of a soluble and an insoluble drug on the disintegration of tablets made of microcrystalline cellulose and dicalcium phosphate dihydrate. Pharmaceutica acta Helvetiae, 1983, Volume: 58, Issue:9-10 Topics: Amitriptyline; Calcium Phosphates; Cellulose; Excipients; Hydrochlorothiazide; Solubility; Tablets	1983
The role of the displacement-time waveform in the determination of Heckel behaviour under dynamic conditions in a compaction simulator and a fully-instrumented rotary tablet machine. The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:6 Topics: Calcium Phosphates; Cellulose; Evaluation Studies as Topic; Lactose; Pressure; Tablets; Technology, Pharmaceutical	1994
Thermophysical properties of some pharmaceutical excipients compressed in tablets. Pharmaceutical research, 1995, Volume: 12, Issue:11 Topics: Calcium Phosphates; Calorimetry, Differential Scanning; Cellulose; Chemical Phenomena; Chemistry, Physical; Drug Stability; Excipients; Lactose; Lubrication; Tablets; Thermodynamics	1995
Thermodynamic analysis of energy dissipation by pharmaceutical tablets during stress unloading. Journal of pharmaceutical sciences, 1994, Volume: 83, Issue:6 Topics: Acetaminophen; Calcium Oxalate; Calcium Phosphates; Cellulose; Pressure; Tablets; Thermodynamics	1994
Influence of polymers for use in saliva substitutes on de- and remineralization of enamel in vitro. Caries research, 1997, Volume: 31, Issue:3 Topics: Acetic Acid; Acrylic Resins; Adsorption; Animals; Buffers; Calcium Phosphates; Carboxymethylcellulose Sodium; Cariostatic Agents; Cattle; Cellulose; Crystallization; Dental Enamel; Dental Enamel Solubility; Durapatite; Galactans; Humans; Hydrogen-Ion Concentration; Mannans; Mucins; Plant Gums; Polymers; Polysaccharides, Bacterial; Saliva, Artificial; Sodium Fluoride; Solubility; Swine; Tooth Demineralization; Tooth Remineralization	1997
In vitro evaluation of a new injectable calcium phosphate material. Journal of biomedical materials research, 1998, Mar-15, Volume: 39, Issue:4 Topics: Animals; Bone and Bones; Bone Development; Bone Substitutes; Calcium Phosphates; Cell Line; Cell Survival; Cellulose; Female; Giant Cells; Materials Testing; Rabbits; Rheology	1998
Film-forming polymer-granulated excipients as the matrix materials for controlled release dosage forms. Journal of controlled release : official journal of the Controlled Release Society, 1998, Feb-12, Volume: 51, Issue:2-3 Topics: Acrylic Resins; Angiotensin-Converting Enzyme Inhibitors; Calcium Phosphates; Captopril; Cellulose; Delayed-Action Preparations; Excipients; Gels; Lactose; Microscopy, Electron, Scanning; Particle Size; Polymethacrylic Acids; Surface Properties	1998
Automated system for the on-line monitoring of powder blending processes using near-infrared spectroscopy. Part II. Qualitative approaches to blend evaluation. Journal of pharmaceutical and biomedical analysis, 1998, Volume: 17, Issue:8 Topics: Algorithms; Autoanalysis; Calcium Phosphates; Cellulose; Equipment Design; Fiber Optic Technology; Models, Chemical; Powders; Signal Processing, Computer-Assisted; Software; Spectroscopy, Near-Infrared; Starch; Stearic Acids; Technology, Pharmaceutical	1998
Occurrence of fragmentation during compression of pellets prepared from a 4 to 1 mixture of dicalcium phosphate dihydrate and microcrystalline cellulose. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 1999, Volume: 7, Issue:3 Topics: Calcium Phosphates; Cellulose; Crystallization; Drug Compounding; Tablets	1999
Tabletting behaviour of pellets of a series of porosities--a comparisonbetween pellets of two different compositions. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 1999, Volume: 8, Issue:1 Topics: Calcium Phosphates; Cellulose; Drug Compounding; Excipients; Hardness; Permeability; Porosity; Powders; Pressure; Tablets; Tensile Strength	1999
A new theoretical model to characterize the densification behavior of tableting materials. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2000, Volume: 49, Issue:3 Topics: Algorithms; Calcium Phosphates; Cellulose; Drug Compounding; Excipients; Hypromellose Derivatives; Methylcellulose; Models, Theoretical; Pressure; Tablets; Theophylline; Time Factors	2000
Effect of diluents on tablet integrity and controlled drug release. Drug development and industrial pharmacy, 2000, Volume: 26, Issue:7 Topics: Calcium Phosphates; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Hot Temperature; Lactose; Tablets; Waxes	2000
Starch acetates--multifunctional direct compression excipients. Pharmaceutical research, 2000, Volume: 17, Issue:9 Topics: Calcium Phosphates; Cellulose; Excipients; Solubility; Starch; Tablets	2000
Time dependence of elastic recovery for characterization of tableting materials. Pharmaceutical development and technology, 2001, Volume: 6, Issue:1 Topics: Calcium Phosphates; Carrageenan; Cellulose; Crystallization; Elasticity; Humidity; Materials Testing; Tablets; Technology, Pharmaceutical; Temperature	2001
An evaluation of three-dimensional modeling of compaction cycles by analyzing the densification behavior of binary and ternary mixtures. Pharmaceutical development and technology, 2001, Volume: 6, Issue:3 Topics: Biocompatible Materials; Calcium Phosphates; Cellulose; Drug Compounding; Models, Chemical; Tablets; Theophylline	2001
Micromeritic and packing properties of diclofenac pellets and effects of some formulation variables. Drug development and industrial pharmacy, 2001, Volume: 27, Issue:8 Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcium Phosphates; Cellulose; Diclofenac; Drug Compounding; Excipients; Gelatin; Methacrylates; Microscopy, Electron, Scanning; Particle Size; Porosity; Powders	2001
Estimation of capping incidence by indentation fracture tests. AAPS pharmSci, 2001, Volume: 3, Issue:1 Topics: Acetaminophen; Calcium Phosphates; Cellulose; Materials Testing; Powders; Stearic Acids; Tablets	2001
Replica of human dentin treated with different desensitizing agents: a methodological SEM study in vitro. Brazilian dental journal, 2002, Volume: 13, Issue:2 Topics: Acid Etching, Dental; Calcium Phosphates; Cellulose; Citric Acid; Dental Impression Materials; Dentin; Dentin Sensitivity; Epoxy Resins; Glutaral; Gold; Humans; Methacrylates; Microscopy, Electron, Scanning; Oxalates; Protective Agents; Replica Techniques; Smear Layer; Surface Properties; Temperature; Time Factors	2002
The effect of excipients on the stability of levothyroxine sodium pentahydrate tablets. International journal of pharmaceutics, 2003, Oct-02, Volume: 264, Issue:1-2 Topics: Adsorption; Calcium Phosphates; Cellulose; Chromatography, High Pressure Liquid; Drug Compounding; Drug Packaging; Drug Stability; Excipients; Hydrogen-Ion Concentration; Kinetics; Lactose; Mannitol; Starch; Tablets; Thyroxine; Water; Wettability	2003
Development of a dual approach to assess powder flow from avalanching behavior. AAPS PharmSciTech, 2000, Jul-21, Volume: 1, Issue:3 Topics: Aerosols; Calcium Phosphates; Cellulose; Excipients; Lactose; Multivariate Analysis; Particle Size; Powders; Starch	2000
Experimental study of wet granulation in fluidized bed: impact of the binder properties on the granule morphology. International journal of pharmaceutics, 2007, Apr-04, Volume: 334, Issue:1-2 Topics: Calcium Phosphates; Cellulose; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Chromatography, Ion Exchange; Excipients; Mannitol; Pharmaceutical Preparations; Porosity; Tomography, X-Ray	2007
Comparison of different dry binders for roll compaction/dry granulation. Pharmaceutical development and technology, 2007, Volume: 12, Issue:5 Topics: Antihypertensive Agents; Biological Availability; Calcium Phosphates; Cellulose; Excipients; Hardness; Hydrochlorothiazide; Particle Size; Povidone; Powders; Solubility; Tablets; Technology, Pharmaceutical; Tensile Strength	2007
A novel method for estimating solid fraction of roller-compacted ribbons. Drug development and industrial pharmacy, 2008, Volume: 34, Issue:2 Topics: Calcium Phosphates; Cellulose; Excipients; Lactose; Models, Theoretical; Powders; Surface Properties; Tablets; Technology, Pharmaceutical	2008
Effect of particle size on compaction of materials with different deformation mechanisms with and without lubricants. AAPS PharmSciTech, 2008, Volume: 9, Issue:2 Topics: Calcium Phosphates; Cellulose; Chemistry, Pharmaceutical; Drug Compounding; Elasticity; Excipients; Lubricants; Particle Size; Powders; Starch; Stearic Acids; Technology, Pharmaceutical; Tensile Strength; Time Factors; Viscosity	2008
Preparation and evaluation of an ispaghula based directly compressible matrixing agent for controlled release. Acta pharmaceutica (Zagreb, Croatia), 2008, Volume: 58, Issue:3 Topics: Acetaminophen; Analgesics, Non-Narcotic; Calcium Phosphates; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Compounding; Excipients; Hypromellose Derivatives; Kinetics; Lactose; Methylcellulose; Models, Chemical; Psyllium; Solubility; Tablets; Technology, Pharmaceutical	2008
Influence of formulation composition and processing on the content uniformity of low-dose tablets manufactured at kilogram scale. Pharmaceutical development and technology, 2009, Volume: 14, Issue:5 Topics: Calcium Phosphates; Cellulose; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Lactose; Tablets	2009
Effects of alpha-DT cement with hydroxypropyl cellulose on bone augmentation within a titanium cap in the rabbit calvarium. Dental materials journal, 2010, Volume: 29, Issue:2 Topics: Absorbable Implants; Animals; Bone Cements; Bone Diseases; Bone Regeneration; Calcification, Physiologic; Calcium Phosphates; Cellulose; Guided Tissue Regeneration; Haversian System; Image Processing, Computer-Assisted; Male; Materials Testing; Osteoblasts; Osteoclasts; Rabbits; Skull; Time Factors; Titanium	2010
Changes in the specific surface area of tablets composed of pharmaceutical materials with various deformation behaviors. Drug development and industrial pharmacy, 2011, Volume: 37, Issue:2 Topics: Calcium Phosphates; Cellulose; Excipients; Lactose; Pressure; Tablets; Tensile Strength	2011
Scale-up model describing the impact of lubrication on tablet tensile strength. International journal of pharmaceutics, 2010, Oct-31, Volume: 399, Issue:1-2 Topics: Calcium Phosphates; Cellulose; Drug Compounding; Lactose; Lubricants; Lubrication; Models, Chemical; Stearic Acids; Tablets; Tensile Strength	2010
Effect of different excipients on the physical characteristics of granules and tablets with carbamazepine prepared with polyethylene glycol 6000 by fluidized hot-melt granulation (FHMG). AAPS PharmSciTech, 2011, Volume: 12, Issue:4 Topics: Anticonvulsants; Calcium Phosphates; Carbamazepine; Cellulose; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Excipients; Hot Temperature; Kinetics; Lactose; Mannitol; Particle Size; Polyethylene Glycols; Powders; Solubility; Starch; Tablets; Technology, Pharmaceutical	2011
Incorporating Turbula mixers into a blending scale-up model for evaluating the effect of magnesium stearate on tablet tensile strength and bulk specific volume. International journal of pharmaceutics, 2012, Jun-15, Volume: 429, Issue:1-2 Topics: Calcium Phosphates; Cellulose; Drug Compounding; Equipment Design; Excipients; Lactose; Lubrication; Stearic Acids; Tablets; Tensile Strength	2012
Understanding the effect of environmental history on bilayer tablet interfacial shear strength. Pharmaceutical research, 2013, Volume: 30, Issue:5 Topics: Calcium Phosphates; Cellulose; Humidity; Shear Strength; Tablets	2013
Deformation properties of pharmaceutical excipients determined using an in-die and out-die method. International journal of pharmaceutics, 2013, Mar-25, Volume: 446, Issue:1-2 Topics: Calcium Phosphates; Cellulose; Disaccharides; Drug Compounding; Elasticity; Excipients; Lactose; Models, Theoretical; Sodium Chloride; Starch; Sugar Alcohols; Technology, Pharmaceutical	2013
Multilayer laminar co-extrudate as a novel controlled release dosage form. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013, Jul-16, Volume: 49, Issue:4 Topics: Administration, Oral; Calcium Phosphates; Cellulose; Coumarins; Delayed-Action Preparations; Dosage Forms; Excipients; Hypromellose Derivatives; Lactose; Methylcellulose; Propranolol; Technology, Pharmaceutical; Water	2013
Evaluation of some compression aids in tableting of roller compacted swellable core drug layer. International journal of pharmaceutics, 2013, Sep-10, Volume: 453, Issue:2 Topics: Calcium Phosphates; Cellulose; Compressive Strength; Drug Compounding; Excipients; Hardness; Hypromellose Derivatives; Lactose; Methylcellulose; Starch; Tablets; Xylitol	2013
The impact of roller compaction and tablet compression on physicomechanical properties of pharmaceutical excipients. Pharmaceutical development and technology, 2014, Volume: 19, Issue:5 Topics: Calcium Phosphates; Cellulose; Drug Compounding; Excipients; Hardness; Lactose; Pressure; Tablets; Tensile Strength	2014
On the links between elastic constants and effective elastic behavior of pharmaceutical compacts: importance of poisson's ratio and use of bulk modulus. Journal of pharmaceutical sciences, 2013, Volume: 102, Issue:11 Topics: Analgesics, Non-Narcotic; Calcium Phosphates; Cellulose; Drug Compounding; Elastic Modulus; Ibuprofen; Mannitol; Powders; Stress, Mechanical; Tablets	2013
A formulation strategy for solving the overgranulation problem in high shear wet granulation. Journal of pharmaceutical sciences, 2014, Volume: 103, Issue:8 Topics: Calcium Phosphates; Cellulose; Drug Compounding; Excipients; Lactose; Tablets; Tensile Strength	2014
Granulation of increasingly hydrophobic formulations using a twin screw granulator. International journal of pharmaceutics, 2014, Nov-20, Volume: 475, Issue:1-2 Topics: Calcium Phosphates; Carboxymethylcellulose Sodium; Cellulose; Chemical Phenomena; Chemistry, Pharmaceutical; Drug Compounding; England; Excipients; Hydrophobic and Hydrophilic Interactions; Lactose; Materials Testing; Particle Size; Placebos; Quality Control; Reproducibility of Results; Surface Properties; Time Factors; Water	2014
Commercial scale validation of a process scale-up model for lubricant blending of pharmaceutical powders. International journal of pharmaceutics, 2014, Nov-20, Volume: 475, Issue:1-2 Topics: Algorithms; Calcium Phosphates; Cellulose; Chemical Phenomena; Chemistry, Pharmaceutical; Compressive Strength; Drug Compounding; Excipients; Lactose; Lubricants; Lubrication; Mechanical Phenomena; Models, Chemical; Pharmaceutic Aids; Pharmaceutical Preparations; Quality Control; Reproducibility of Results; Stearic Acids; Tablets; Tensile Strength	2014
Compaction behavior and deformation mechanism of directly compressible textured mannitol in a rotary tablet press simulator. International journal of pharmaceutics, 2015, Nov-10, Volume: 495, Issue:1 Topics: Calcium Phosphates; Cellulose; Lactose; Mannitol; Mechanical Phenomena; Powders; Tablets; Technology, Pharmaceutical	2015
Macroindentation hardness measurement-Modernization and applications. International journal of pharmaceutics, 2016, Jun-15, Volume: 506, Issue:1-2 Topics: Calcium Phosphates; Cellulose; Chemistry, Pharmaceutical; Drug Compounding; Excipients; Hardness; Porosity; Powders; Tablets; Technology, Pharmaceutical	2016
A compressibility based model for predicting the tensile strength of directly compressed pharmaceutical powder mixtures. International journal of pharmaceutics, 2017, Oct-05, Volume: 531, Issue:1 Topics: Calcium Phosphates; Cellulose; Drug Compounding; Excipients; Mannitol; Models, Theoretical; Powders; Pressure; Tablets; Tensile Strength	2017
The suitability of common compressibility equations for characterizing plasticity of diverse powders. International journal of pharmaceutics, 2017, Oct-30, Volume: 532, Issue:1 Topics: Algorithms; Calcium Phosphates; Celecoxib; Cellulose; Compressive Strength; Excipients; Hardness; Ibuprofen; Lactose; Mannitol; Powders; Stearic Acids	2017
Understanding Compression-Induced Amorphization of Crystalline Posaconazole. Molecular pharmaceutics, 2019, 02-04, Volume: 16, Issue:2 Topics: Calcium Phosphates; Calorimetry, Differential Scanning; Cellulose; Finite Element Analysis; Magnetic Resonance Spectroscopy; Molecular Structure; Particle Size; Phthalic Acids; Triazoles	2019
Investigation of the effects of particle size on fragmentation during tableting. International journal of pharmaceutics, 2020, Feb-25, Volume: 576 Topics: Calcium Phosphates; Cellulose; Chemistry, Pharmaceutical; Excipients; Lactose; Particle Size; Pressure; Stearic Acids; Tablets; Technology, Pharmaceutical; Tensile Strength	2020