calcitonin and tauro-24-25-dihydrofusidate

calcitonin has been researched along with tauro-24-25-dihydrofusidate* in 1 studies

Other Studies

1 other study(ies) available for calcitonin and tauro-24-25-dihydrofusidate

Article	Year
The bioavailability of intranasal salmon calcitonin in healthy volunteers with and without a permeation enhancer. Pharmaceutical research, 1994, Volume: 11, Issue:5 Serum levels of radioimmunoactive salmon calcitonin (sCT) were determined in 10 healthy volunteers after intranasal administration (IN) of 100-, 205-, and 450-IU of sCT with 0.5% sodium tauro-24,25-dihydrofusidate (STDHF), a 200-IU commercial IN formulation, and a 100-IU intramuscular (IM) formulation. Relative to the IM dose, the bioavailabilities of the IN formulations containing 0.5% STDHF were 3.9, 7.9, and 7.4%, respectively. The 200-IU commercial formulation resulted in serum levels above the limit of detection in only 5 of 10 patients, with an average bioavailability of 1.6%. Topics: Adjuvants, Pharmaceutic; Administration, Intranasal; Adult; Biological Availability; Calcitonin; Female; Fusidic Acid; Humans; Male; Radioimmunoassay	1994

Article

Year

The bioavailability of intranasal salmon calcitonin in healthy volunteers with and without a permeation enhancer.

Pharmaceutical research, 1994, Volume: 11, Issue:5

Serum levels of radioimmunoactive salmon calcitonin (sCT) were determined in 10 healthy volunteers after intranasal administration (IN) of 100-, 205-, and 450-IU of sCT with 0.5% sodium tauro-24,25-dihydrofusidate (STDHF), a 200-IU commercial IN formulation, and a 100-IU intramuscular (IM) formulation. Relative to the IM dose, the bioavailabilities of the IN formulations containing 0.5% STDHF were 3.9, 7.9, and 7.4%, respectively. The 200-IU commercial formulation resulted in serum levels above the limit of detection in only 5 of 10 patients, with an average bioavailability of 1.6%.

Topics: Adjuvants, Pharmaceutic; Administration, Intranasal; Adult; Biological Availability; Calcitonin; Female; Fusidic Acid; Humans; Male; Radioimmunoassay

1994