calcimycin has been researched along with meglitinide* in 1 studies
1 other study(ies) available for calcimycin and meglitinide
| Article | Year |
|---|---|
Conformational analysis of the calcium complexes formed by meglitinide analogs.
The conformation of calcium complexes formed with meglitinide and its hypoglycemic analogs KAD-1229, A-4166, S 3075 and repaglinide was analyzed by a semi-empirical procedure, which includes calculation of the molecular hydrophobicity potential. The calcium complexes formed with KAD-1229, A-4166, repaglinide or its enantiomer, displayed favourable attributes to act as ionophores. Such was not the case for the poorly efficient insulinotropic agent meglitinide and the biologically inactive enantiomer of A-4166. The configuration of the calcium complex formed with S 3075 also failed to display the features required for a high ionophoretic capacity. Topics: Benzamides; Calcimycin; Calcium; Chemical Phenomena; Chemistry, Physical; Hypoglycemic Agents; Ionophores; Models, Molecular; Molecular Conformation; Stereoisomerism | 1995 |