calcimycin has been researched along with kyotorphin* in 1 studies
1 other study(ies) available for calcimycin and kyotorphin
Article | Year |
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Inositol 1,4,5-trisphosphate-gated calcium transport through plasma membranes in nerve terminals.
We developed new biochemical approaches to demonstrate the presence of inositol 1,4,5-triphosphate (InsP3)-gated calcium channels in presynaptic plasma membranes (SPM) and their involvement in the presynaptic receptor-mediated Ca2+ influx into nerve terminals. In perfusion experiments using SPM vesicles preloaded with 45Ca2+, InsP3 elicited the release of 45CA2+ into perfusates in a saturable manner. The InsP3- evoked 45Ca2+ release from resealed SPM vesicles was more potent than that from resealed vesicles using any other subcellular fractions. Here we also report the involvement of InsP3-gated mechanisms in the presynaptic receptor-mediated Ca2+ influx into synaptosomes (nerve terminals) by use of such resealed vesicles reconstituted with purified Gi1. Topics: Adenosine Triphosphate; Animals; Biological Transport; Calcimycin; Calcium; Calcium Channels; Cell Membrane; Endorphins; Inositol 1,4,5-Trisphosphate; Ion Channel Gating; Kinetics; Male; Nerve Endings; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Synaptic Vesicles; Virulence Factors, Bordetella | 1996 |