calcimycin has been researched along with exaprolol* in 1 studies
1 other study(ies) available for calcimycin and exaprolol
Article | Year |
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Effect of chloroquine on isolated mast cells.
Chloroquine liberated a relatively low amount of histamine from isolated rat mast cells. In a dose-dependent way, this drug inhibited histamine liberation from mast cells stimulated with compound 48/80, A23187, concanavalin A plus phosphatidylserine (Con A + PS) and abolished histamine liberation induced by exaprolol. The degranulation was decreased in cells stimulated with 48/80, Con A + PS and exaprolol. Chloroquine significantly inhibited the formation of thromboxane B2 in mast cells stimulated with 48/80, Con A + PS and A23187. We assume that chloroquine interferes with mast cells at a plasmic membrane site as well as intracellularly. Topics: Adrenergic beta-Antagonists; Animals; Calcimycin; Chloroquine; Concanavalin A; Dose-Response Relationship, Drug; Histamine Release; Male; Mast Cells; p-Methoxy-N-methylphenethylamine; Phosphatidylserines; Propanolamines; Rats; Rats, Inbred Strains; Thromboxane B2 | 1991 |