calcimycin and carboprostacyclin

calcimycin has been researched along with carboprostacyclin* in 1 studies

Other Studies

1 other study(ies) available for calcimycin and carboprostacyclin

Article	Year
[Effect of adenylate cyclase system activation on Na+/H+-exchange in human platelets]. Biulleten' eksperimental'noi biologii i meditsiny, 1988, Volume: 106, Issue:9 In experiments with human platelets it has been shown, that stimulation of adenylate cyclase by carbacycline (CC)--a stable analog of prostacyclin, does not affect the initial pHi decrease caused by thrombin and PAF, but it abolishes the second phase of pHi changes, a pHi increase resulted from Na+/H+ exchange activation. CC also abolishes pHi increase induced by ionophore A23187 and the activator of protein kinase C, phorbol ester (TPA). The results obtained suggest that cAMP exerts inhibitory action on the agonist induced activation of Na+/H+ exchange but does not affect its pHi-sensitivity in the resting cell. Topics: Adenylyl Cyclases; Blood Platelets; Calcimycin; Carrier Proteins; Cyclic AMP; Enzyme Activation; Epoprostenol; Humans; In Vitro Techniques; Protons; Sodium; Sodium-Hydrogen Exchangers	1988

Article

Year

[Effect of adenylate cyclase system activation on Na+/H+-exchange in human platelets].

Biulleten' eksperimental'noi biologii i meditsiny, 1988, Volume: 106, Issue:9

In experiments with human platelets it has been shown, that stimulation of adenylate cyclase by carbacycline (CC)--a stable analog of prostacyclin, does not affect the initial pHi decrease caused by thrombin and PAF, but it abolishes the second phase of pHi changes, a pHi increase resulted from Na+/H+ exchange activation. CC also abolishes pHi increase induced by ionophore A23187 and the activator of protein kinase C, phorbol ester (TPA). The results obtained suggest that cAMP exerts inhibitory action on the agonist induced activation of Na+/H+ exchange but does not affect its pHi-sensitivity in the resting cell.

Topics: Adenylyl Cyclases; Blood Platelets; Calcimycin; Carrier Proteins; Cyclic AMP; Enzyme Activation; Epoprostenol; Humans; In Vitro Techniques; Protons; Sodium; Sodium-Hydrogen Exchangers

1988