calcimycin has been researched along with aniline* in 1 studies
1 other study(ies) available for calcimycin and aniline
| Article | Year |
|---|---|
The use of the divalent calcium-ionophore A23187 as a biochemical tool in pharmacological and in vitro toxicological studies.
The use of A23187 as a biochemical tool is described. A23187 was used to elucidate the mechanisms of intracellular transport and secretion of N-hydroxylated aniline metabolites in rat hepatocyte primary culture. Results indicate a membrane-bound intracellular transport. Also, A23187 induced macrophages in their anti-tumour cytostatic activity using P815 tumour cells in in vitro co-cultures of macrophages and tumour cells. Results indicate the activating role of A23187 in macrophage leukotriene C4 release and enhanced macrophage anti-tumour activity. In conclusion, A23187 proved to be a useful tool in studying calcium dependent metabolic processes. Topics: Aniline Compounds; Animals; Calcimycin; Calcium; Carcinogens; Cell Division; Colchicine; Ionophores; Liver; Lymphocyte Activation; Macrophages; Monensin; Rats; Tumor Cells, Cultured | 1996 |