calanolide a has been researched along with warfarin in 30 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 17 (56.67) | 18.2507 |
2000's | 13 (43.33) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Boyd, MR; Buckheit, RW; Cardellina, JH; Cragg, GM; Currens, MJ; Fuller, RW; Gustafson, KR; Hughes, SH; Kashman, Y; McMahon, JB | 1 |
Boyd, MR; Boyer, PL; Currens, MJ; Hughes, SH; McMahon, JB | 1 |
Boyd, MR; Currens, MJ; Hizi, A; Hughes, SH; McMahon, JB; Shaharabany, M; Tal, R | 1 |
Boulanger, WA; Chen, W; Cibulski, M; Flavin, MT; Flavin, TM; Greenwood, EM; Hughes, SH; Khilevich, A; Kucherenko, A; Lin, L; Pengsuparp, T; Pezzuto, JM; Rizzo, JD; Sheinkman, AK; Shone, RL; Vilaychack, V; Xu, ZQ | 1 |
Boyd, MR; Cardellina, JH; Covington, CD; Fuller, RW; Gulakowski, RJ; Krepps, BL; McKee, TC; McMahon, JB | 1 |
Boyd, MR; Cardellina, JH; Fuller, RW; Galinis, DL; Gulakowski, RJ; McKee, TC; McMahon, JB | 1 |
Boyd, MR; Buckheit, RW; Currens, MJ; Gulakowski, RJ; Gustafson, KR; Mariner, JM; McMahon, JB; Moran, RA | 1 |
Boyd, MR; Currens, MJ; Mariner, JM; McMahon, JB | 1 |
Buckheit, RW; Flavin, MT; Khilevich, A; Liao, S; Mar, AA; Sheinkman, AK; Stup, TL; Xu, ZQ; Zembower, DE | 1 |
Dharmaratne, HR; Mata-Greenwood, E; Pezzuto, JM; Wanigasekera, WM | 1 |
Chen, W; Madden, TL; Newman, RA | 1 |
Buckheit, RW; Flavin, MT; Khilevich, A; Lin, L; Rizzo, JD; Stup, TL; Xu, ZQ; Zembower, DE | 1 |
Borgel, S; Elder, C; Flavin, MT; Hollingshead, MG; Khilevich, A; Xu, ZQ | 1 |
Bader, JP; Buckheit, RW; Fliakas-Boltz, V; Kinjerski, TL; Osterling, MC; Russell, J; Stup, TL; Weigand, A; White, EL | 1 |
Allen, LB; Buckheit, RW; Flavin, MT; Jenta, T; Kern, ER; Tseng, CK; Westbrook, L; Xu, ZQ | 1 |
Buckheit, R; Flavin, MT; Motakis, D; Parniak, MA; Quan, Y; Wainberg, MA; Xu, ZQ | 1 |
Flavin, MT; Frank, P; Kardatzke, J; Norris, KJ; Weinberg, DS; Wertz, P; Xu, ZQ | 1 |
Buckheit, RW; Flavin, M; Russell, JD; Xu, ZQ | 1 |
Creagh, T; Dutta, B; Eiznhamer, DA; Flavin, MT; Giltner, J; Ruckle, JL; Tolbert, DT; Xu, ZQ | 1 |
Hanna, L | 1 |
Barrow, E; Barrow, WW; Flavin, MT; Lin, YM; Suling, WJ; Westbrook, L; Xu, ZQ | 1 |
Ikeda, T; Ishikawa, T; Kumamoto, T; Sekino, E; Tanaka, T | 1 |
Tarby, CM | 1 |
Xie, L; Zhou, T | 1 |
Beutler, JA; Bona, MK; Budihas, SR; Crouch, RJ; Gaidamakov, S; Gorshkova, I; Le Grice, SF; McMahon, JB; Parniak, MA; Wamiru, A | 1 |
Auwerx, J; Balzarini, J; Camarasa, MJ; Ceccherini-Silberstein, F; De Clercq, E; Gago, F; Perno, CF; Rodríguez-Barrios, F; San-Félix, A; Velázquez, S | 1 |
Kostova, I | 1 |
Chen, Z; Han, C; Li, L; Liu, G; Liu, L; Ma, T; Wang, L; Xue, H | 1 |
3 review(s) available for calanolide a and warfarin
Article | Year |
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Recent advances in the development of next generation non-nucleoside reverse transcriptase inhibitors.
Topics: Anti-HIV Agents; Clinical Trials as Topic; Coumarins; HIV Reverse Transcriptase; Humans; Imidazoles; Molecular Structure; Nitriles; Patents as Topic; Pyranocoumarins; Pyridazines; Pyrimidines; Quinazolines; Reverse Transcriptase Inhibitors; Sulfur Compounds | 2004 |
[Progress in HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs)].
Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Coumarins; Cyclopropanes; Delavirdine; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Conformation; Molecular Structure; Nevirapine; Oxazines; Pyranocoumarins; Reverse Transcriptase Inhibitors | 2004 |
Coumarins as inhibitors of HIV reverse transcriptase.
Topics: Acquired Immunodeficiency Syndrome; Animals; Anti-HIV Agents; Camphor; Coumarins; Drug Design; Drug Therapy, Combination; Humans; Lactones; Pyranocoumarins; Reverse Transcriptase Inhibitors; Structure-Activity Relationship | 2006 |
1 trial(s) available for calanolide a and warfarin
Article | Year |
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Safety and pharmacokinetics of single doses of (+)-calanolide a, a novel, naturally occurring nonnucleoside reverse transcriptase inhibitor, in healthy, human immunodeficiency virus-negative human subjects.
Topics: Adolescent; Adult; Age Factors; Aged; Area Under Curve; Cohort Studies; Coumarins; Female; Humans; Male; Middle Aged; Pyranocoumarins; Reverse Transcriptase Inhibitors | 2001 |
26 other study(ies) available for calanolide a and warfarin
Article | Year |
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The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum.
Topics: Antiviral Agents; Chromatography, Liquid; Coumarins; Cytopathogenic Effect, Viral; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Pyranocoumarins; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Trees; Tumor Cells, Cultured; Virus Replication | 1992 |
Analysis of nonnucleoside drug-resistant variants of human immunodeficiency virus type 1 reverse transcriptase.
Topics: Amino Acid Sequence; Antiviral Agents; Benzimidazoles; Coumarins; Drug Resistance, Microbial; HIV; HIV Reverse Transcriptase; Pyranocoumarins; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiazoles; Thymine | 1993 |
Specific inhibition of the reverse transcriptase of human immunodeficiency virus type 1 and the chimeric enzymes of human immunodeficiency virus type 1 and type 2 by nonnucleoside inhibitors.
Topics: Antiviral Agents; Coumarins; HIV Reverse Transcriptase; HIV-1; HIV-2; Mutagenesis, Insertional; Pyranocoumarins; Recombinant Fusion Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase | 1993 |
Synthesis, chromatographic resolution, and anti-human immunodeficiency virus activity of (+/-)-calanolide A and its enantiomers.
Topics: Antiviral Agents; Chromatography, High Pressure Liquid; Coumarins; HIV; HIV Reverse Transcriptase; Nucleic Acid Synthesis Inhibitors; Pyranocoumarins; RNA-Directed DNA Polymerase; Stereoisomerism | 1996 |
New pyranocoumarins isolated from Calophyllum lanigerum and Calophyllum teysmannii.
Topics: Antiviral Agents; Coumarins; HIV; Latex; Magnetic Resonance Spectroscopy; Plant Extracts; Pyranocoumarins; Spectrometry, Mass, Fast Atom Bombardment; Structure-Activity Relationship | 1996 |
Structure-activity modifications of the HIV-1 inhibitors (+)-calanolide A and (-)-calanolide B.
Topics: Anti-HIV Agents; Antiviral Agents; Coumarins; Cytopathogenic Effect, Viral; Humans; Pyranocoumarins; Structure-Activity Relationship; Tumor Cells, Cultured | 1996 |
Antiviral activity and mechanism of action of calanolide A against the human immunodeficiency virus type-1.
Topics: Anti-HIV Agents; Cell Line; Coumarins; HIV-1; Humans; Nucleic Acid Synthesis Inhibitors; Pyranocoumarins; Reverse Transcriptase Inhibitors | 1996 |
Kinetic analysis of inhibition of human immunodeficiency virus type-1 reverse transcriptase by calanolide A.
Topics: Anti-HIV Agents; Binding Sites; Coumarins; HIV Reverse Transcriptase; Humans; Kinetics; Pyranocoumarins; Reverse Transcriptase Inhibitors | 1996 |
Structural analogues of the calanolide anti-HIV agents. Modification of the trans-10,11-dimethyldihydropyran-12-ol ring (ring C).
Topics: Anti-HIV Agents; Cell Survival; Coumarins; HIV Reverse Transcriptase; HIV-1; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Pyranocoumarins; Reverse Transcriptase Inhibitors; Tumor Cells, Cultured | 1997 |
Inhibition of human immunodeficiency virus type 1 reverse transcriptase activity by cordatolides isolated from Calophyllum cordato-oblongum.
Topics: Anti-HIV Agents; Coumarins; HIV Reverse Transcriptase; HIV-1; Plants; Pyranocoumarins; Reverse Transcriptase Inhibitors | 1998 |
Pharmaceutical properties of related calanolide compounds with activity against human immunodeficiency virus.
Topics: Administration, Oral; Animals; Anti-HIV Agents; Area Under Curve; Biological Availability; Coumarins; Drug Stability; Half-Life; Male; Mice; Pyranocoumarins; Stereoisomerism | 1998 |
In vitro anti-human immunodeficiency virus (HIV) activity of the chromanone derivative, 12-oxocalanolide A, a novel NNRTI.
Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cell Line; Chromones; Coumarins; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Leukocytes; Macrophages; Monocytes; Pyranocoumarins; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Structure-Activity Relationship; Virus Replication | 1998 |
In vivo anti-HIV activity of (+)-calanolide A in the hollow fiber mouse model.
Topics: Animals; Anti-HIV Agents; Cell Line; Cell Survival; Cells, Cultured; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV Core Protein p24; HIV Reverse Transcriptase; Humans; Macrophages; Mice; Pyranocoumarins; Time Factors; Zidovudine | 1999 |
Unique anti-human immunodeficiency virus activities of the nonnucleoside reverse transcriptase inhibitors calanolide A, costatolide, and dihydrocostatolide.
Topics: Anti-HIV Agents; Benzopyrans; Cells, Cultured; Coumarins; Drug Resistance, Microbial; Drug Synergism; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Microbial Sensitivity Tests; Pyranocoumarins; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Stereoisomerism | 1999 |
Plant-derived and semi-synthetic calanolide compounds with in vitro activity against both human immunodeficiency virus type 1 and human cytomegalovirus.
Topics: Anti-HIV Agents; Cells, Cultured; Coumarins; Cytomegalovirus; Cytopathogenic Effect, Viral; HIV-1; Humans; Microbial Sensitivity Tests; Pyranocoumarins; Viral Plaque Assay | 2000 |
Sensitivity and resistance to (+)-calanolide A of wild-type and mutated forms of HIV-1 reverse transcriptase.
Topics: Coumarins; Drug Resistance; HIV Reverse Transcriptase; HIV-1; Mutation; Nevirapine; Pyranocoumarins; Reverse Transcriptase Inhibitors; Virus Replication | 1999 |
Calanolide looks promising.
Topics: Anti-HIV Agents; Clinical Trials, Phase II as Topic; Coumarins; Dose-Response Relationship, Drug; HIV Infections; Humans; Malaysia; Prognosis; Pyranocoumarins; Sensitivity and Specificity; Singapore; United States | 2000 |
Quantification of (+)-calanolide A, a novel and naturally occurring anti-HIV agent, by high-performance liquid chromatography in plasma from rat, dog and human.
Topics: Administration, Oral; Animals; Anti-HIV Agents; Area Under Curve; Chromatography, High Pressure Liquid; Cohort Studies; Coumarins; Dogs; Female; HIV Seronegativity; Humans; Male; Pyranocoumarins; Rats; Reference Standards; Reproducibility of Results; Spectrometry, Fluorescence | 2000 |
Anti-HIV-1 activity of calanolides used in combination with other mechanistically diverse inhibitors of HIV-1 replication.
Topics: Antiviral Agents; Cell Line; Coumarins; Drug Therapy, Combination; HIV Protease Inhibitors; HIV-1; Humans; Microbial Sensitivity Tests; Pyranocoumarins; Reverse Transcriptase Inhibitors; Virus Replication | 2000 |
Natural compound shows anti-HIV activity.
Topics: Animals; Anti-HIV Agents; Coumarins; Humans; Plant Extracts; Pyranocoumarins | 1998 |
Calanolide A: a natural non-nucleoside reverse transcriptase inhibitor.
Topics: Anti-HIV Agents; Coumarins; HIV Infections; Humans; Multicenter Studies as Topic; Plant Extracts; Pyranocoumarins; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; United States | 1999 |
Anti-HIV natural product (+)-calanolide A is active against both drug-susceptible and drug-resistant strains of Mycobacterium tuberculosis.
Topics: Animals; Anti-HIV Agents; Antineoplastic Combined Chemotherapy Protocols; Antitubercular Agents; Cell Line; Chlorocebus aethiops; Cisplatin; Coumarins; DNA; Drug Resistance, Bacterial; Ifosfamide; Inhibitory Concentration 50; Macrophages; Microbial Sensitivity Tests; Mitomycin; Mycobacterium tuberculosis; Pyranocoumarins; Rifampin; RNA; Vero Cells; Virus Replication | 2004 |
Concise synthesis of anti-HIV-1 active (+)-inophyllum B and (+)-calanolide A by application of (-)-quinine-catalyzed intramolecular oxo-Michael addition.
Topics: Anti-HIV Agents; Catalysis; Coumarins; Molecular Structure; Pyranocoumarins; Quinine; Stereoisomerism | 2004 |
Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones.
Topics: Anti-HIV Agents; Benzocycloheptenes; Binding Sites; Coumarins; HIV-1; Pyranocoumarins; Reverse Transcriptase Inhibitors; Ribonuclease H; Tropolone | 2005 |
The role of Thr139 in the human immunodeficiency virus type 1 reverse transcriptase sensitivity to (+)-calanolide A.
Topics: Coumarins; HIV Reverse Transcriptase; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Pyranocoumarins; Reverse Transcriptase Inhibitors; Threonine | 2005 |
Chemical library and structure-activity relationships of 11-demethyl-12-oxo calanolide A analogues as anti-HIV-1 agents.
Topics: Anti-HIV Agents; Cell Line; Chromones; Combinatorial Chemistry Techniques; Coumarins; HIV-1; Humans; Pyranocoumarins; Stereoisomerism; Structure-Activity Relationship | 2008 |