Page last updated: 2024-08-24

calanolide a and warfarin

calanolide a has been researched along with warfarin in 30 studies

Research

Studies (30)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	17 (56.67)	18.2507
2000's	13 (43.33)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Boyd, MR; Buckheit, RW; Cardellina, JH; Cragg, GM; Currens, MJ; Fuller, RW; Gustafson, KR; Hughes, SH; Kashman, Y; McMahon, JB	1
Boyd, MR; Boyer, PL; Currens, MJ; Hughes, SH; McMahon, JB	1
Boyd, MR; Currens, MJ; Hizi, A; Hughes, SH; McMahon, JB; Shaharabany, M; Tal, R	1
Boulanger, WA; Chen, W; Cibulski, M; Flavin, MT; Flavin, TM; Greenwood, EM; Hughes, SH; Khilevich, A; Kucherenko, A; Lin, L; Pengsuparp, T; Pezzuto, JM; Rizzo, JD; Sheinkman, AK; Shone, RL; Vilaychack, V; Xu, ZQ	1
Boyd, MR; Cardellina, JH; Covington, CD; Fuller, RW; Gulakowski, RJ; Krepps, BL; McKee, TC; McMahon, JB	1
Boyd, MR; Cardellina, JH; Fuller, RW; Galinis, DL; Gulakowski, RJ; McKee, TC; McMahon, JB	1
Boyd, MR; Buckheit, RW; Currens, MJ; Gulakowski, RJ; Gustafson, KR; Mariner, JM; McMahon, JB; Moran, RA	1
Boyd, MR; Currens, MJ; Mariner, JM; McMahon, JB	1
Buckheit, RW; Flavin, MT; Khilevich, A; Liao, S; Mar, AA; Sheinkman, AK; Stup, TL; Xu, ZQ; Zembower, DE	1
Dharmaratne, HR; Mata-Greenwood, E; Pezzuto, JM; Wanigasekera, WM	1
Chen, W; Madden, TL; Newman, RA	1
Buckheit, RW; Flavin, MT; Khilevich, A; Lin, L; Rizzo, JD; Stup, TL; Xu, ZQ; Zembower, DE	1
Borgel, S; Elder, C; Flavin, MT; Hollingshead, MG; Khilevich, A; Xu, ZQ	1
Bader, JP; Buckheit, RW; Fliakas-Boltz, V; Kinjerski, TL; Osterling, MC; Russell, J; Stup, TL; Weigand, A; White, EL	1
Allen, LB; Buckheit, RW; Flavin, MT; Jenta, T; Kern, ER; Tseng, CK; Westbrook, L; Xu, ZQ	1
Buckheit, R; Flavin, MT; Motakis, D; Parniak, MA; Quan, Y; Wainberg, MA; Xu, ZQ	1
Flavin, MT; Frank, P; Kardatzke, J; Norris, KJ; Weinberg, DS; Wertz, P; Xu, ZQ	1
Buckheit, RW; Flavin, M; Russell, JD; Xu, ZQ	1
Creagh, T; Dutta, B; Eiznhamer, DA; Flavin, MT; Giltner, J; Ruckle, JL; Tolbert, DT; Xu, ZQ	1
Hanna, L	1
Barrow, E; Barrow, WW; Flavin, MT; Lin, YM; Suling, WJ; Westbrook, L; Xu, ZQ	1
Ikeda, T; Ishikawa, T; Kumamoto, T; Sekino, E; Tanaka, T	1
Tarby, CM	1
Xie, L; Zhou, T	1
Beutler, JA; Bona, MK; Budihas, SR; Crouch, RJ; Gaidamakov, S; Gorshkova, I; Le Grice, SF; McMahon, JB; Parniak, MA; Wamiru, A	1
Auwerx, J; Balzarini, J; Camarasa, MJ; Ceccherini-Silberstein, F; De Clercq, E; Gago, F; Perno, CF; Rodríguez-Barrios, F; San-Félix, A; Velázquez, S	1
Kostova, I	1
Chen, Z; Han, C; Li, L; Liu, G; Liu, L; Ma, T; Wang, L; Xue, H	1

Reviews

3 review(s) available for calanolide a and warfarin

Article	Year
Recent advances in the development of next generation non-nucleoside reverse transcriptase inhibitors. Current topics in medicinal chemistry, 2004, Volume: 4, Issue:10 Topics: Anti-HIV Agents; Clinical Trials as Topic; Coumarins; HIV Reverse Transcriptase; Humans; Imidazoles; Molecular Structure; Nitriles; Patents as Topic; Pyranocoumarins; Pyridazines; Pyrimidines; Quinazolines; Reverse Transcriptase Inhibitors; Sulfur Compounds	2004
[Progress in HIV non-nucleoside reverse transcriptase inhibitors (NNRTIs)]. Yao xue xue bao = Acta pharmaceutica Sinica, 2004, Volume: 39, Issue:8 Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Coumarins; Cyclopropanes; Delavirdine; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; Humans; Molecular Conformation; Molecular Structure; Nevirapine; Oxazines; Pyranocoumarins; Reverse Transcriptase Inhibitors	2004
Coumarins as inhibitors of HIV reverse transcriptase. Current HIV research, 2006, Volume: 4, Issue:3 Topics: Acquired Immunodeficiency Syndrome; Animals; Anti-HIV Agents; Camphor; Coumarins; Drug Design; Drug Therapy, Combination; Humans; Lactones; Pyranocoumarins; Reverse Transcriptase Inhibitors; Structure-Activity Relationship	2006

Trials

1 trial(s) available for calanolide a and warfarin

Article	Year
Safety and pharmacokinetics of single doses of (+)-calanolide a, a novel, naturally occurring nonnucleoside reverse transcriptase inhibitor, in healthy, human immunodeficiency virus-negative human subjects. Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:5 Topics: Adolescent; Adult; Age Factors; Aged; Area Under Curve; Cohort Studies; Coumarins; Female; Humans; Male; Middle Aged; Pyranocoumarins; Reverse Transcriptase Inhibitors	2001

Article

Year

Safety and pharmacokinetics of single doses of (+)-calanolide a, a novel, naturally occurring nonnucleoside reverse transcriptase inhibitor, in healthy, human immunodeficiency virus-negative human subjects.

Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:5

Topics: Adolescent; Adult; Age Factors; Aged; Area Under Curve; Cohort Studies; Coumarins; Female; Humans; Male; Middle Aged; Pyranocoumarins; Reverse Transcriptase Inhibitors

2001

Other Studies

26 other study(ies) available for calanolide a and warfarin

Article	Year
The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum. Journal of medicinal chemistry, 1992, Jul-24, Volume: 35, Issue:15 Topics: Antiviral Agents; Chromatography, Liquid; Coumarins; Cytopathogenic Effect, Viral; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Hydrolysis; Magnetic Resonance Spectroscopy; Pyranocoumarins; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Trees; Tumor Cells, Cultured; Virus Replication	1992
Analysis of nonnucleoside drug-resistant variants of human immunodeficiency virus type 1 reverse transcriptase. Journal of virology, 1993, Volume: 67, Issue:4 Topics: Amino Acid Sequence; Antiviral Agents; Benzimidazoles; Coumarins; Drug Resistance, Microbial; HIV; HIV Reverse Transcriptase; Pyranocoumarins; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiazoles; Thymine	1993
Specific inhibition of the reverse transcriptase of human immunodeficiency virus type 1 and the chimeric enzymes of human immunodeficiency virus type 1 and type 2 by nonnucleoside inhibitors. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:5 Topics: Antiviral Agents; Coumarins; HIV Reverse Transcriptase; HIV-1; HIV-2; Mutagenesis, Insertional; Pyranocoumarins; Recombinant Fusion Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase	1993
Synthesis, chromatographic resolution, and anti-human immunodeficiency virus activity of (+/-)-calanolide A and its enantiomers. Journal of medicinal chemistry, 1996, Mar-15, Volume: 39, Issue:6 Topics: Antiviral Agents; Chromatography, High Pressure Liquid; Coumarins; HIV; HIV Reverse Transcriptase; Nucleic Acid Synthesis Inhibitors; Pyranocoumarins; RNA-Directed DNA Polymerase; Stereoisomerism	1996
New pyranocoumarins isolated from Calophyllum lanigerum and Calophyllum teysmannii. Journal of natural products, 1996, Volume: 59, Issue:8 Topics: Antiviral Agents; Coumarins; HIV; Latex; Magnetic Resonance Spectroscopy; Plant Extracts; Pyranocoumarins; Spectrometry, Mass, Fast Atom Bombardment; Structure-Activity Relationship	1996
Structure-activity modifications of the HIV-1 inhibitors (+)-calanolide A and (-)-calanolide B. Journal of medicinal chemistry, 1996, Oct-25, Volume: 39, Issue:22 Topics: Anti-HIV Agents; Antiviral Agents; Coumarins; Cytopathogenic Effect, Viral; Humans; Pyranocoumarins; Structure-Activity Relationship; Tumor Cells, Cultured	1996
Antiviral activity and mechanism of action of calanolide A against the human immunodeficiency virus type-1. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:2 Topics: Anti-HIV Agents; Cell Line; Coumarins; HIV-1; Humans; Nucleic Acid Synthesis Inhibitors; Pyranocoumarins; Reverse Transcriptase Inhibitors	1996
Kinetic analysis of inhibition of human immunodeficiency virus type-1 reverse transcriptase by calanolide A. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:2 Topics: Anti-HIV Agents; Binding Sites; Coumarins; HIV Reverse Transcriptase; Humans; Kinetics; Pyranocoumarins; Reverse Transcriptase Inhibitors	1996
Structural analogues of the calanolide anti-HIV agents. Modification of the trans-10,11-dimethyldihydropyran-12-ol ring (ring C). Journal of medicinal chemistry, 1997, Mar-14, Volume: 40, Issue:6 Topics: Anti-HIV Agents; Cell Survival; Coumarins; HIV Reverse Transcriptase; HIV-1; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Pyranocoumarins; Reverse Transcriptase Inhibitors; Tumor Cells, Cultured	1997
Inhibition of human immunodeficiency virus type 1 reverse transcriptase activity by cordatolides isolated from Calophyllum cordato-oblongum. Planta medica, 1998, Volume: 64, Issue:5 Topics: Anti-HIV Agents; Coumarins; HIV Reverse Transcriptase; HIV-1; Plants; Pyranocoumarins; Reverse Transcriptase Inhibitors	1998
Pharmaceutical properties of related calanolide compounds with activity against human immunodeficiency virus. Journal of pharmaceutical sciences, 1998, Volume: 87, Issue:9 Topics: Administration, Oral; Animals; Anti-HIV Agents; Area Under Curve; Biological Availability; Coumarins; Drug Stability; Half-Life; Male; Mice; Pyranocoumarins; Stereoisomerism	1998
In vitro anti-human immunodeficiency virus (HIV) activity of the chromanone derivative, 12-oxocalanolide A, a novel NNRTI. Bioorganic & medicinal chemistry letters, 1998, Aug-18, Volume: 8, Issue:16 Topics: Acquired Immunodeficiency Syndrome; Anti-HIV Agents; Cell Line; Chromones; Coumarins; Drug Design; HIV Reverse Transcriptase; HIV-1; Humans; In Vitro Techniques; Leukocytes; Macrophages; Monocytes; Pyranocoumarins; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Structure-Activity Relationship; Virus Replication	1998
In vivo anti-HIV activity of (+)-calanolide A in the hollow fiber mouse model. Bioorganic & medicinal chemistry letters, 1999, Jan-18, Volume: 9, Issue:2 Topics: Animals; Anti-HIV Agents; Cell Line; Cell Survival; Cells, Cultured; Coumarins; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; HIV Core Protein p24; HIV Reverse Transcriptase; Humans; Macrophages; Mice; Pyranocoumarins; Time Factors; Zidovudine	1999
Unique anti-human immunodeficiency virus activities of the nonnucleoside reverse transcriptase inhibitors calanolide A, costatolide, and dihydrocostatolide. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:8 Topics: Anti-HIV Agents; Benzopyrans; Cells, Cultured; Coumarins; Drug Resistance, Microbial; Drug Synergism; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Microbial Sensitivity Tests; Pyranocoumarins; Reverse Transcriptase Inhibitors; Simian Immunodeficiency Virus; Stereoisomerism	1999
Plant-derived and semi-synthetic calanolide compounds with in vitro activity against both human immunodeficiency virus type 1 and human cytomegalovirus. Antiviral chemistry & chemotherapy, 2000, Volume: 11, Issue:1 Topics: Anti-HIV Agents; Cells, Cultured; Coumarins; Cytomegalovirus; Cytopathogenic Effect, Viral; HIV-1; Humans; Microbial Sensitivity Tests; Pyranocoumarins; Viral Plaque Assay	2000
Sensitivity and resistance to (+)-calanolide A of wild-type and mutated forms of HIV-1 reverse transcriptase. Antiviral therapy, 1999, Volume: 4, Issue:4 Topics: Coumarins; Drug Resistance; HIV Reverse Transcriptase; HIV-1; Mutation; Nevirapine; Pyranocoumarins; Reverse Transcriptase Inhibitors; Virus Replication	1999
Calanolide looks promising. AIDS patient care and STDs, 2000, Volume: 14, Issue:4 Topics: Anti-HIV Agents; Clinical Trials, Phase II as Topic; Coumarins; Dose-Response Relationship, Drug; HIV Infections; Humans; Malaysia; Prognosis; Pyranocoumarins; Sensitivity and Specificity; Singapore; United States	2000
Quantification of (+)-calanolide A, a novel and naturally occurring anti-HIV agent, by high-performance liquid chromatography in plasma from rat, dog and human. Journal of chromatography. B, Biomedical sciences and applications, 2000, Jun-09, Volume: 742, Issue:2 Topics: Administration, Oral; Animals; Anti-HIV Agents; Area Under Curve; Chromatography, High Pressure Liquid; Cohort Studies; Coumarins; Dogs; Female; HIV Seronegativity; Humans; Male; Pyranocoumarins; Rats; Reference Standards; Reproducibility of Results; Spectrometry, Fluorescence	2000
Anti-HIV-1 activity of calanolides used in combination with other mechanistically diverse inhibitors of HIV-1 replication. Antiviral chemistry & chemotherapy, 2000, Volume: 11, Issue:5 Topics: Antiviral Agents; Cell Line; Coumarins; Drug Therapy, Combination; HIV Protease Inhibitors; HIV-1; Humans; Microbial Sensitivity Tests; Pyranocoumarins; Reverse Transcriptase Inhibitors; Virus Replication	2000
Natural compound shows anti-HIV activity. AIDS patient care and STDs, 1998, Volume: 12, Issue:5 Topics: Animals; Anti-HIV Agents; Coumarins; Humans; Plant Extracts; Pyranocoumarins	1998
Calanolide A: a natural non-nucleoside reverse transcriptase inhibitor. BETA : bulletin of experimental treatments for AIDS : a publication of the San Francisco AIDS Foundation, 1999, Volume: 12, Issue:2 Topics: Anti-HIV Agents; Coumarins; HIV Infections; Humans; Multicenter Studies as Topic; Plant Extracts; Pyranocoumarins; Randomized Controlled Trials as Topic; Reverse Transcriptase Inhibitors; United States	1999
Anti-HIV natural product (+)-calanolide A is active against both drug-susceptible and drug-resistant strains of Mycobacterium tuberculosis. Bioorganic & medicinal chemistry, 2004, Mar-01, Volume: 12, Issue:5 Topics: Animals; Anti-HIV Agents; Antineoplastic Combined Chemotherapy Protocols; Antitubercular Agents; Cell Line; Chlorocebus aethiops; Cisplatin; Coumarins; DNA; Drug Resistance, Bacterial; Ifosfamide; Inhibitory Concentration 50; Macrophages; Microbial Sensitivity Tests; Mitomycin; Mycobacterium tuberculosis; Pyranocoumarins; Rifampin; RNA; Vero Cells; Virus Replication	2004
Concise synthesis of anti-HIV-1 active (+)-inophyllum B and (+)-calanolide A by application of (-)-quinine-catalyzed intramolecular oxo-Michael addition. The Journal of organic chemistry, 2004, Apr-16, Volume: 69, Issue:8 Topics: Anti-HIV Agents; Catalysis; Coumarins; Molecular Structure; Pyranocoumarins; Quinine; Stereoisomerism	2004
Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones. Nucleic acids research, 2005, Volume: 33, Issue:4 Topics: Anti-HIV Agents; Benzocycloheptenes; Binding Sites; Coumarins; HIV-1; Pyranocoumarins; Reverse Transcriptase Inhibitors; Ribonuclease H; Tropolone	2005
The role of Thr139 in the human immunodeficiency virus type 1 reverse transcriptase sensitivity to (+)-calanolide A. Molecular pharmacology, 2005, Volume: 68, Issue:3 Topics: Coumarins; HIV Reverse Transcriptase; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Pyranocoumarins; Reverse Transcriptase Inhibitors; Threonine	2005
Chemical library and structure-activity relationships of 11-demethyl-12-oxo calanolide A analogues as anti-HIV-1 agents. Journal of medicinal chemistry, 2008, Mar-13, Volume: 51, Issue:5 Topics: Anti-HIV Agents; Cell Line; Chromones; Combinatorial Chemistry Techniques; Coumarins; HIV-1; Humans; Pyranocoumarins; Stereoisomerism; Structure-Activity Relationship	2008