caffeine and uracil
caffeine has been researched along with uracil in 102 studies
Research
Studies (102)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 54 (52.94) | 18.7374 |
| 1990's | 22 (21.57) | 18.2507 |
| 2000's | 17 (16.67) | 29.6817 |
| 2010's | 8 (7.84) | 24.3611 |
| 2020's | 1 (0.98) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Duffy, EM; Jorgensen, WL | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Bearne, SL; Lunn, FA; Roy, AC | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Clarke, CH; Shankel, DM | 1 |
| Davidson, D; Golding, BG | 1 |
| Grodzinsky, DM; Gudkov, IN | 1 |
| Lohmann, W; Sapper, H; Schimmack, W | 1 |
| Lohmann, W; Schimmack, W | 1 |
| Díez, JL; González-Fernández, A; López-Sáez, JF | 1 |
| Ebihara, A; Hashiguchi, M | 1 |
| Kalow, W; Tang, BK | 1 |
| Iriah, J; Kadar, D; Kalow, W; Qian, L; Tang, BK; Yip, J | 1 |
| Beitins, IZ; Kilbane, AJ; Manis, M; Silbart, LK; Weber, WW | 1 |
| Dressman, JB; Meadows, KC | 1 |
| Chan, MM; Kou, M; Kumana, CR; Lauder, IJ; Wong, KL; Wong, RW | 1 |
| Butler, MA; Kadlubar, FF; Lang, NP; Massengill, JP; Talaska, G; Teitel, CH | 1 |
| Griener, JC; Morris, ME; Msall, ME | 1 |
| Chaleby, K; el-Yazigi, A; Martin, CR | 1 |
| Hildebrand, M; Seifert, W | 1 |
| Badoual, J; Carrier, O; Moran, C; Olive, G; Pons, G; Rey, E; Richard, MO | 2 |
| Alhaider, AA; Hijazi, AA; Mustafa, AA | 1 |
| Lorenzo, B; Reidenberg, MM | 1 |
| Bartle, WR; Hardy, BG; Lemieux, C; Walker, SE | 1 |
| Dayer, P; Gascon, MP; Leemann, T | 1 |
| Campbell, ME; Kalow, W; Spielberg, SP | 1 |
| Abbruzzi, R; Bastone, A; Bianchi, M; Bonati, M; Catalani, P; Guaitani, A; Latini, R; Pantarotto, C; Szczawinska, K | 1 |
| Kadar, D; Kalow, W; Tang, BK | 1 |
| González-Fernández, A; Hernández, P; López-Sáez, JF | 1 |
| De Taeye, J; Zeegers-Huyskens, T | 1 |
| Ebihara, R; Fujii, Y; Itahara, T; Seto, Y; Tada, M | 1 |
| Tamiya, H | 1 |
| Harris, WJ | 1 |
| Pearson, PL | 1 |
| Dertinger, H; Nicolau, C | 1 |
| Phelps, P; Tse, RL; Urban, D | 1 |
| Janovska, E; Vizdalova, M; Zhestianikov, VD | 1 |
| Bishop, RJ; Sueoka, N | 1 |
| Fraser, L; Harris, WJ; Mitchell, AI | 1 |
| Bacon, V; Duffield, AM; Halpern, B; Hoyano, Y; Pereira, WE; Summons, RE | 1 |
| Abola, EE; Deutsch, HF; Edmundson, AB; Ely, KR; Fausch, MD; Girling, RL; Schiffer, M; Westholm, FA | 1 |
| Janovská, E; Vízdalová, M; Zhestjanikov, VD | 1 |
| Hirsch, I; Janderová, B; Vondrejs, V | 1 |
| Caldas, LR; De Souza, CM; Gomes, RA; Mayr, LM | 1 |
| Nicolau, C; Singh, BB | 1 |
| Vitkin, BS | 1 |
| Voogd, CE | 1 |
| Carstens, E; Dietz, G; Goldner, H | 1 |
| Kneser, H; Metzger, K; Sauerbier, W | 1 |
| Connors, KA; Mollica, JA | 1 |
| Hedrick, CE; Koeppel, TA | 1 |
| Bruskov, VI; Okon, MS | 1 |
| Amato, G; Bonati, M; Filippeschi, S; Garattini, S; Malfiore, C; Mantovani, A; Pepe, S; Peri, G; Polentarutti, N | 1 |
| Grant, DM; Kalow, W; Tang, BK | 2 |
| Arnaud, MJ; Bracco, I; Clerc, MF; Sauvageat, JL | 1 |
| Ferrero, JL; Neims, AH | 1 |
| Arnaud, M; Erba, E; Filippeschi, S; Garattini, S; Mantovani, A; Morasca, L; Peri, G; Spreafico, F | 1 |
| Armstrong, SW; Davidson, D | 1 |
| González-Fernández, A; López-Sáez, JF | 1 |
| Bonati, M; Garattini, S; Latini, R; Marzi, E | 1 |
| Arvela, P; Klebovich, I; Pelkonen, O; Rautio, A; Salonpää, P; Sotaniemi, EA | 1 |
| Bresnick, E; McQuilkin, SH; Nierenberg, DW | 1 |
| Cribb, AE; Gillespie, CT; Isbrucker, R; Levatte, T; Renton, KW; Tsui, B | 1 |
| Gee, RL; Kloth, MT; Messing, EM; Swaminathan, S | 1 |
| Galteau, MM; Gueguen, R; Pontes, ZB; Siest, G; Vincent-Viry, M | 1 |
| Bell, DA; Brubaker, LH; Butler, MA; Kadlubar, FF; Lucier, GW; Stephens, EA; Taylor, JA; Wiest, J | 1 |
| Arvela, P; Klebovich, I; Pelkonen, O | 1 |
| Bechtel, PR; Bechtel, YC; Bonaiti-Pellie, C; Magnette, J; Poisson, N | 1 |
| Kawakubo, Y; Nakamori, M; Ohkido, M; Schöpf, E | 1 |
| Amano, T; Hatori, S; Imada, T; Ito, H; Kondo, J; Maehara, T; Rino, Y; Shiozawa, M; Suzuki, Y; Takahashi, M | 1 |
| Asaeda, A; Ide, H; Kubo, K; Matsuyama, S; Ohashi, F; Shiomi, A; Takamori, Y | 1 |
| Bernal, ML; Fanlo, A; Juste, JL; Lanuza, J; Mayayo, E; Sáenz, MA; Sinués, B | 1 |
| Ghosh, S; Sen, R | 1 |
| Bechtel, PR; Bechtel, YC; Brientini, MP; Hrusovsky, S; Lelouët, H; Mantion, G; Miguet, JP; Paintaud, G | 1 |
| Banerjee, K; Lang, N; Leyland-Jones, B; Massengill, J; Nowell, S; Wong, P | 1 |
| Biollaz, J; Décosterd, LA; Kesselring, UW; Nyéki, A | 1 |
| Cao, XM; Ling, SS; Lu, JF; Yi, T; Zhuo, HT | 1 |
| Cao, XM; Lin, SS; Lu, JF; Yi, T; Zhuo, HT | 1 |
| Cui, X; Guo, R; Li, C; Wang, B; Xu, Z | 1 |
| Abraham, K; Bauer, S; Brockmöller, J; Geusau, A; Helge, H; Tosun, Y | 1 |
| Biollaz, J; Buclin, T; Decosterd, LA; Nyéki, A | 1 |
| JEFFREY, JJ; SCHANKER, LS; TOCCO, DJ | 1 |
| SIMON, MI; VANVUNAKIS, H | 1 |
| CAILLET, J; CLAVERIE, P; PULLMAN, B | 1 |
| Borlak, J; Cascorbi, I; Erb, K; Fuhr, U; Hermann, R; Illauer, M; Jetter, A; Kinzig-Schippers, M; Smith, G; Sörgel, F; Wolf, H | 1 |
| Blaszkewicz, M; Bolt, HM; Dannappel, D; Golka, K; Selinski, S | 1 |
| Bracho, M; De la Torre, C; Del Campo, A; Guíñez, J; Marcano, L | 1 |
| Li, J; Peng, XQ; Xu, JP; Zhang, J | 1 |
| Brüning, T; John, A; Rihs, HP; Scherenberg, M; Seidel, A | 1 |
| Brøsen, K; Damkier, P; Grandjean, P; Halling, J; Nielsen, F; Petersen, MS; Weihe, P | 1 |
| Asprodini, EK; Begas, E; Kouvaras, E; Papakosta, S; Tsakalof, A | 1 |
| Fuhr, U; Jetter, A; Kinzig, M; Rodamer, M; Sörgel, F; Tomalik-Scharte, D | 1 |
| Ashida, H; Hashimoto, T; Kanazawa, K; Nakabayashi, H; Nishiumi, S | 1 |
| Aklillu, E; Carrillo, JA; Djordjevic, N; Fukasawa, T; Gervasini, G; Jankovic, S; Suda, A; Ueda, N | 1 |
| Aklillu, E; Bertilsson, L; Carrillo, JA; Djordjevic, N; Karlsson, S; Roh, HK; Ueda, N | 1 |
| Fan, XR; Li, XY; Li, YF; Li, YP; Liu, YN; Yang, M; Yao, XC; Yin, YM; Yuan, M; Zhu, JB | 1 |
| Ahluwalia, N; Pao, CI; Pfeiffer, CM; Rybak, ME; Sternberg, MR | 1 |
| Fan, Z; Huang, Q; Lin, S; Qiu, L; Su, L; Zhang, X | 1 |
| Aklillu, E; Bertilsson, L; Carrillo, JA; Djordjevic, N; Makonnen, E | 1 |
| Au, PCM; Chau, YP; Cheng, VKF; Cheung, CL; Kung, AWC; Li, GHY; Sing, CW; Tan, KCB | 1 |
Reviews
2 review(s) available for caffeine and uracil
| Article | Year |
|---|---|
Antimutagenesis in microbial systems.
Topics: Acridines; Antipsychotic Agents; Bacteria; Caffeine; Chloramphenicol; Dactinomycin; Dibenzocycloheptenes; DNA Repair; Escherichia coli; Fungi; Genes; Histidine; Manganese; Mutagens; Mutation; Phenothiazines; Polyamines; Purine Nucleosides; Quinacrine; Radiation Effects; Rosaniline Dyes; Ultraviolet Rays; Uracil; Warfarin | 1975 |
Short-lived free radicals in aqueous solutions of biomolecules.
Topics: Amino Acids; Bromouracil; Caffeine; Chemistry, Organic; Cytosine; Disulfides; Electrons; Free Radicals; Hydrogen Peroxide; Nucleic Acids; Nucleosides; Nucleotides; Organic Chemistry Phenomena; Orotic Acid; Peptides; Proteins; Purines; Pyrimidines; Sulfhydryl Compounds; Thymine; Uracil | 1971 |
Trials
1 trial(s) available for caffeine and uracil
| Article | Year |
|---|---|
Antipyrine, coumarin and glipizide affect n-acetylation measured by caffeine test.
Topics: Acetylation; Adult; Analysis of Variance; Antipyrine; Caffeine; Coumarins; Diabetes Mellitus, Type 2; Female; Glipizide; Humans; Hypoglycemic Agents; Male; Middle Aged; Uracil; Xanthines | 1995 |
Other Studies
99 other study(ies) available for caffeine and uracil
| Article | Year |
|---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids.
Topics: Carbon-Nitrogen Ligases; Enzyme Inhibitors; Escherichia coli; Kinetics; Methylation; Structure-Activity Relationship; Uric Acid; Xanthines | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Differential behaviour of sister nuclei in methylxanthine-induced binucleate cells.
Topics: Caffeine; Cell Cycle; Cell Division; Cell Nucleus; Fabaceae; Karyometry; Plants, Medicinal; Uracil; Xanthines | 1978 |
Induction by gamma-radiation of DNA synthesis in radicle cells of germinating seeds of Pisum sativum l.
Topics: Acriflavine; Caffeine; Cobalt Radioisotopes; DNA Repair; DNA Replication; Gamma Rays; Hydroxyurea; Radiation Genetics; Seeds; Uracil | 1976 |
Stacking interactions of nucleobases: NMR-investigations. II. Self-association of purine-and pyrimidine-derivatives.
Topics: Adenine; Adenosine; Caffeine; Chemical Phenomena; Chemistry; Cytosine; Deuterium; Hypoxanthines; Magnetic Resonance Spectroscopy; Polymers; Purines; Pyrimidines; Thermodynamics; Uracil; Uric Acid; Water | 1975 |
Association of sexual hormones with nucleobases in water: NMR-investigations.
Topics: Adenine; Adenosine; Caffeine; Chemical Phenomena; Chemistry; Cytosine; Deuterium; Estradiol; Hypoxanthines; Magnetic Resonance Spectroscopy; Purines; Pyrimidines; Testosterone; Thermodynamics; Uracil; Uric Acid; Water | 1975 |
Mechanism of mitotic synchronization induced by 5-aminouracil.
Topics: Caffeine; Cell Division; Cell Nucleus; DNA; Kinetics; Mitosis; Plant Cells; Plants; Uracil | 1976 |
Acetylation polymorphism of caffeine in a Japanese population.
Topics: Acetylation; Adult; Caffeine; Humans; Japan; Male; Metabolism; Phenotype; Polymorphism, Genetic; Uracil; Xanthines | 1992 |
Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities.
Topics: Adult; Caffeine; Cytochrome P-450 Enzyme System; Drug Interactions; Ethanol; Female; Humans; Longitudinal Studies; Male; Uracil; Xanthine Oxidase | 1991 |
Caffeine as a metabolic probe: validation of its use for acetylator phenotyping.
Topics: Acetylation; Acetyltransferases; Adult; Caffeine; Humans; Phenotype; Polymorphism, Genetic; Sulfamethazine; Time Factors; Uracil; Uric Acid; Xanthines | 1991 |
Human N-acetylation genotype determination with urinary caffeine metabolites.
Topics: Acetylation; Caffeine; Chromatography, High Pressure Liquid; Gene Frequency; Genetics, Population; Genotype; Humans; Nitrogen; Pedigree; Phenotype; Theophylline; Time Factors; Uracil; Uric Acid; Xanthines | 1990 |
Mechanism of acyclovir uptake in rat jejunum.
Topics: Acyclovir; Animals; Caffeine; Chromatography, High Pressure Liquid; Diffusion; In Vitro Techniques; Jejunum; Male; Perfusion; Rats; Rats, Inbred Strains; Uracil | 1990 |
Lack of association between slow acetylator status and spontaneous lupus erythematosus.
Topics: Acetylation; Adult; Caffeine; China; Chromatography, High Pressure Liquid; Female; Humans; Lupus Erythematosus, Systemic; Phenotype; Uracil; Xanthines | 1990 |
Determination of carcinogenic arylamine N-oxidation phenotype in humans by analysis of caffeine urinary metabolites.
Topics: Acetylation; Arylamine N-Acetyltransferase; Biotransformation; Caffeine; Cytochrome P-450 Enzyme System; Disease Susceptibility; Humans; Isoenzymes; Oxidation-Reduction; Phenotype; Theophylline; Uracil; Urinary Bladder Neoplasms; Xanthines | 1990 |
N-acetylator variability in Down's syndrome: characterization with caffeine.
Topics: Acetylation; Adolescent; Adult; Caffeine; Child; Chromatography, High Pressure Liquid; Down Syndrome; Female; Humans; Male; Middle Aged; Phenotype; Uracil; Xanthines | 1989 |
A simplified and rapid test for acetylator phenotyping by use of the peak height ratio of two urinary caffeine metabolites.
Topics: Acetylation; Acetyltransferases; Adult; Aged; Arylamine N-Acetyltransferase; Caffeine; Female; Humans; Male; Middle Aged; Phenotype; Sulfasalazine; Uracil; Xanthines | 1989 |
Determination of acetylator phenotype in Caucasians with caffeine.
Topics: Acetylation; Adolescent; Adult; Aged; Caffeine; Female; Humans; Male; Middle Aged; Phenotype; Sex Factors; Smoking; Uracil; White People; Xanthines | 1989 |
Maturation of AFMU excretion in infants.
Topics: Acetylation; Caffeine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Infant; Infant, Newborn; Infant, Premature; Phenotype; Uracil | 1989 |
Study on the renal and cardiovascular activities of aminouracil derivatives.
Topics: Animals; Caffeine; Diuretics; Electrolytes; Female; Hemodynamics; In Vitro Techniques; Kidney; Male; Muscle Relaxants, Central; Rabbits; Rats; Rats, Inbred Strains; Uracil; Urodynamics | 1989 |
Potential artifacts in the use of caffeine to determine acetylation phenotype.
Topics: Acetylation; Caffeine; False Positive Reactions; Humans; Phenotype; Time Factors; Uracil; Xanthines | 1989 |
Maturation of caffeine metabolic pathways in infancy.
Topics: Acetylation; Administration, Oral; Adult; Age Factors; Apnea; Caffeine; Chromatography, High Pressure Liquid; Citrates; Drug Combinations; Female; Humans; Hydroxylation; Infant; Infant, Newborn; Infant, Premature; Male; Pierre Robin Syndrome; Time Factors; Uracil; Xanthines | 1988 |
Interindividual and intraindividual variability in acetylation: characterization with caffeine.
Topics: Acetylation; Acetyltransferases; Adult; Caffeine; Chromatography, High Pressure Liquid; Female; Humans; Male; Phenotype; Time Factors; Uracil; Xanthines | 1988 |
[Evaluation of a caffeine test for determining the phenotype of N-acetyltransferase].
Topics: Acetyltransferases; Caffeine; Chromatography, High Pressure Liquid; Humans; In Vitro Techniques; Liver; Microsomes, Liver; Phenotype; Polymorphism, Genetic; Uracil | 1987 |
A urinary metabolite ratio that reflects systemic caffeine clearance.
Topics: Adult; Age Factors; Asian People; Caffeine; Child; Child, Preschool; Contraceptives, Oral; Cytochrome P-450 Enzyme System; Female; Humans; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Smoking; Time Factors; Uracil; Uric Acid; White People; Xanthines | 1987 |
Metabolism of caffeine to 6-amino-5-[N-methylformylamino]-1,3-dimethyluracil in the isolated, perfused liver from control or phenobarbital-, beta-naphthoflavone- and 3-methylcholanthrene-pretreated rats.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Caffeine; Chromatography, High Pressure Liquid; Drug Interactions; Kinetics; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Uracil | 1987 |
An alternative test for acetylator phenotyping with caffeine.
Topics: Acetylation; Caffeine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Longitudinal Studies; Male; Methods; Phenotype; Time Factors; Uracil | 1987 |
Effect of caffeine and adenosine on G2 repair: mitotic delay and chromosome damage.
Topics: Adenosine; Caffeine; Chromosomes; DNA Repair; Interphase; Mitosis; Plants; Uracil | 1985 |
Infrared study of the interaction between caffeine and hydroxylic derivatives.
Topics: Caffeine; Chemical Phenomena; Chemistry; Ethylene Dichlorides; Hydroxylation; Spectrophotometry, Infrared; Thermodynamics; Uracil | 1985 |
Reaction of nucleic acids bases and their derivatives with peroxodisulfate ion.
Topics: Caffeine; Chemical Phenomena; Chemistry; Indicators and Reagents; Peroxides; Sodium Compounds; Structure-Activity Relationship; Sulfates; Sulfuric Acids; Thymine; Uracil | 1985 |
Cell differentiation in Chlorella.
Topics: Alanine; Antimetabolites; Azaguanine; Barbiturates; Caffeine; Cell Differentiation; Cell Division; Chloramphenicol; Dihydrostreptomycin Sulfate; Eukaryota; In Vitro Techniques; Microscopy, Electron; Protein Biosynthesis; Sulfates; Thiophenes; Triazines; Uracil | 1963 |
The occurrence of two types of synthesis of deoxyribonucleic acid during normal growth in Bacillus subtilis.
Topics: Azo Compounds; Bacillus subtilis; Caffeine; Carbon Radioisotopes; Centrifugation, Density Gradient; DNA Replication; DNA, Bacterial; Phenols; Thymidine; Thymine; Tritium; Uracil; Uridine | 1973 |
The behavior of chromosomes.
Topics: Acridines; Caffeine; Chloroquine; Depression, Chemical; DNA; DNA Repair; DNA Replication; Floxuridine; Humans; Male; Meiosis; Sex Chromosomes; Spermatogenesis; Spermatozoa; Uracil; Urea | 1973 |
An electron paramagnetic resonance study of short-lived free radicals from nucleic acid constituents and related compounds in aqueous solution.
Topics: Amines; Caffeine; Chemical Phenomena; Chemistry; Electron Spin Resonance Spectroscopy; Free Radicals; Hydroxides; Nucleic Acids; Nucleosides; Thymidine; Uracil; Uridine | 1970 |
Polymorphonuclear leukocyte motility in vitro. VI. Effect of purine and pyrimidine analogues: possible role of cyclic AMP.
Topics: Adenine; Caffeine; Cyclic AMP; Epinephrine; Guanine; Guanosine; Humans; Hypoxanthines; Imidazoles; Leukocytes; Movement; Purines; Pyrimidines; Reserpine; Structure-Activity Relationship; Theophylline; Thymine; Uracil; Uric Acid; Xanthines | 1972 |
[Post-radiation cell repair. 3. Effect of repair inhibitors on the survival of Escherichia coli in relation to growth conditions following UV- and x-radiation].
Topics: Acridines; Bromouracil; Caffeine; Culture Media; DNA; DNA Repair; Escherichia coli; Radiation Effects; Ultraviolet Rays; Uracil | 1972 |
5-Bromouracil-tolerant mutants of Bacillus subtilis.
Topics: Bacillus subtilis; Bromouracil; Caffeine; Carbon Isotopes; Cell Survival; Chromosome Mapping; Culture Media; DNA Replication; DNA, Bacterial; Drug Resistance, Microbial; Mutation; Radiation Effects; Spores, Bacterial; Thymine; Transformation, Genetic; Ultraviolet Rays; Uracil | 1972 |
A comparison of the utilization of thymine and thymidine as precursors for deoxyribonucleic acid synthesis in Bacillus subtilis, and their specific inhibition by 6-(p-hydroxyphenylazo)uracil and caffeine.
Topics: Azo Compounds; Bacillus subtilis; Caffeine; DNA Repair; DNA Replication; DNA, Bacterial; Phenols; Thymidine; Thymine; Tritium; Uracil | 1972 |
Chlorination studies. IV. The reaction of aqueous hypochlorous acid with pyrimidine and purine bases.
Topics: Adenine; Bromouracil; Caffeine; Chemical Phenomena; Chemistry; Guanine; Mass Spectrometry; Purines; Pyrimidines; Sodium Hypochlorite; Spectrophotometry, Ultraviolet; Theophylline; Thymine; Uracil; Xanthines | 1973 |
Binding of 2,4-dinitrophenyl compounds and other small molecules to a crystalline lambda-type Bence-Jones dimer.
Topics: Amino Acid Sequence; Amino Acids; Amyloidosis; Bence Jones Protein; Binding Sites; Caffeine; Chemical Phenomena; Chemistry; Colchicine; Dansyl Compounds; Fluorine; Humans; Immunoglobulin Fragments; Immunoglobulins; Iodine; Macromolecular Substances; Methadone; Models, Structural; Morphine; Nitrobenzenes; Phenanthrolines; Protein Binding; Protein Conformation; Uracil; Vitamin K; X-Ray Diffraction | 1974 |
Effect of dark-repair inhibitors on the survival of Escherichia coli B under different post-irradiation conditions.
Topics: Acridines; Bromouracil; Caffeine; Cell Survival; Culture Media; Depression, Chemical; DNA, Bacterial; Escherichia coli; Radiation Effects; Radiation-Sensitizing Agents; Temperature; Ultraviolet Rays; Uracil | 1971 |
Phases of thymineless death in Escherichia coli 15 TAU.
Topics: Agar; Arginine; Bacteriological Techniques; Bacteriolysis; Caffeine; Cell Division; Cell Survival; Colorimetry; Culture Media; DNA Replication; DNA, Bacterial; Escherichia coli; Genetics, Microbial; Thymine; Time Factors; Tritium; Uracil | 1971 |
[The effects of reductone on irradiated E. coli].
Topics: 1-Propanol; Adenine; Aldehydes; Bacterial Proteins; Caffeine; Carbon Isotopes; Cell Survival; DNA, Bacterial; Escherichia coli; Ketones; Oxidative Phosphorylation; Oxygen Consumption; Phosphorus Isotopes; Radiation Effects; RNA, Bacterial; Time Factors; Ultraviolet Rays; Uracil; Valine | 1970 |
[The effectiveness of chemotherapy of radiation skin cancer].
Topics: Adult; Aged; Antineoplastic Agents; Benzoates; Benzofurans; Cacao; Caffeine; Carcinoma, Squamous Cell; Castor Oil; Colchicine; Female; Humans; Male; Middle Aged; Neoplasms, Radiation-Induced; Ointments; Plant Extracts; Skin; Skin Neoplasms; Uracil | 1972 |
Mutagenic action of ethylene halogenhydrins.
Topics: Bromine; Caffeine; Chlorine; Cyanides; Ethylenes; Genetics, Microbial; Iodine; Klebsiella; Mutagens; Mutation; Uracil | 1969 |
[The alkylation of 5-nitrosouracil derivatives--a new synthesis of caffeine].
Topics: Alkylation; Caffeine; Chemical Phenomena; Chemistry; Nitroso Compounds; Uracil | 1965 |
Evidence of different mechanisms for ultraviolet reactivation and "ordinary host cell reactivation" of phage lambda.
Topics: Caffeine; Chloramphenicol; Coliphages; In Vitro Techniques; Molecular Biology; Mutation; Radiation Effects; Ultraviolet Rays; Uracil | 1965 |
Modification of reaction rates by complex formation. II. Inhibition of the rate of alkaline hydrolysis of methyl trans-cinnamate by some heterocyclic compounds.
Topics: Acetates; Benzimidazoles; Caffeine; Chemical Phenomena; Chemistry; Cinnamates; Guanine; Imidazoles; Purines; Theophylline; Uracil | 1967 |
Effect of functional group substituents on the paper chromatography of purines and pyrimidines.
Topics: Adenine; Caffeine; Chemical Phenomena; Chemistry; Chromatography, Paper; Cytosine; Guanine; Hydrogen-Ion Concentration; Nitriles; Purines; Pyrimidines; Theobromine; Theophylline; Thymine; Uracil; Water; Xanthines | 1967 |
[Thermal characteristics of the C--H...O hydrogen bonds formed by nucleic acid base analogs].
Topics: Acetone; Caffeine; Carbon Tetrachloride; Dimethyl Sulfoxide; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Protons; Solutions; Temperature; Thermodynamics; Uracil | 1984 |
In vitro and in vivo cytotoxicity of possible uracil metabolites of methylxanthines.
Topics: Animals; Caffeine; Cartilage; In Vitro Techniques; Leukemia L1210; Lymphocyte Activation; Mice; Rats; Uracil | 1983 |
A simple test for acetylator phenotype using caffeine.
Topics: Acetylation; Acetyltransferases; Adolescent; Adult; Aged; Caffeine; Chemistry, Organic; Child; Child, Preschool; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Middle Aged; Organic Chemistry Phenomena; Phenotype; Sulfamethazine; Uracil; Xanthines | 1984 |
Polymorphic N-acetylation of a caffeine metabolite.
Topics: Acetylation; Acetyltransferases; Adolescent; Adult; Aged; Asian People; Caffeine; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Phenotype; Polymorphism, Genetic; Sulfamethazine; Uracil; White People | 1983 |
Placental transfer of the major caffeine metabolite in the rat using 6-amino-5[N-formylmethylamino]1,3[Me-14C]-dimethyluracil administered orally or intravenously to the pregnant rat.
Topics: Administration, Oral; Animals; Autoradiography; Caffeine; Feces; Female; Injections, Intravenous; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Inbred Strains; Uracil | 1983 |
Metabolism of caffeine by mouse liver microsomes: GSH or cytosol causes a shift in products from 1,3,7-trimethylurate to a substituted diaminouracil.
Topics: Animals; Biotransformation; Caffeine; Carbon Radioisotopes; Cytosol; Glutathione; Liver; Male; Mice; Mice, Inbred AKR; Microsomes, Liver; Structure-Activity Relationship; Uracil; Uric Acid; Xanthines | 1983 |
In vitro and in vivo cytotoxicity of 6 amino-5-formyl-methylamino-1,3-dimethyl uracil, a uracilic metabolite of caffeine.
Topics: Animals; Caffeine; Cell Division; Female; Humans; In Vitro Techniques; Leukemia L1210; Mice; Mice, Inbred Strains; Uracil | 1982 |
Differences in protein content of sister nuclei: evidence from binucleate and mononucleate cells.
Topics: Caffeine; Cell Cycle; Cell Nucleus; Culture Techniques; Cytoplasm; DNA; Fabaceae; Interphase; Mitosis; Nucleoproteins; Plants, Medicinal; Uracil | 1982 |
Effect of caffeine on G2 repair and its reversion by adenosine.
Topics: Adenosine; Adenosine Triphosphate; Caffeine; Cell Cycle; Chromosome Aberrations; Chromosomes; DNA Repair; Plants; Radiation-Sensitizing Agents; Uracil; Xanthines | 1982 |
Urinary excretion of an uracilic metabolite from caffeine by rat, monkey and man.
Topics: Adult; Animals; Biotransformation; Caffeine; Humans; Macaca fascicularis; Male; Rats; Species Specificity; Theobromine; Theophylline; Uracil; Uric Acid; Xanthines | 1981 |
Analysis of within-subject variation of caffeine metabolism when used to determine cytochrome P4501A2 and N-acetyltransferase-2 activities.
Topics: Adult; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Female; Genetic Variation; Humans; Male; Middle Aged; Oxidoreductases; Phenotype; Spectrophotometry, Ultraviolet; Theophylline; Time Factors; Uracil; Xanthines | 1995 |
Acetylator phenotyping: the urinary caffeine metabolite ratio in slow acetylators correlates with a marker of systemic NAT1 activity.
Topics: 4-Aminobenzoic Acid; Acetylation; Adult; Arylamine N-Acetyltransferase; Biomarkers; Caffeine; Female; Humans; Isoenzymes; Kinetics; Leukocytes, Mononuclear; Male; Middle Aged; Phenotype; Substrate Specificity; Uracil; Xanthines | 1994 |
Expression of N-acetyltransferase (NAT) in cultured human uroepithelial cells.
Topics: Acetylation; Adult; Alleles; Amines; Arylamine N-Acetyltransferase; Biomarkers; Caffeine; Cells, Cultured; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; DNA, Complementary; Epithelial Cells; Epithelium; Female; Gene Expression; Genetic Predisposition to Disease; Humans; Male; Microsomes, Liver; Oxidoreductases; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Risk Factors; Uracil; Ureter; Urinary Bladder Neoplasms; Xanthines | 1994 |
Segregation analyses of four urinary caffeine metabolite ratios implicated in the determination of human acetylation phenotypes.
Topics: Acetylation; Adolescent; Adult; Alleles; Arylamine N-Acetyltransferase; Caffeine; Child; Chromatography, High Pressure Liquid; Family; Female; Gene Frequency; Genes, Recessive; Humans; Male; Middle Aged; Models, Genetic; Models, Statistical; Phenotype; Polymorphism, Genetic; Theophylline; Uracil; Uric Acid; Xanthines | 1994 |
Genotype/phenotype discordance for human arylamine N-acetyltransferase (NAT2) reveals a new slow-acetylator allele common in African-Americans.
Topics: Acetylation; Alleles; Amino Acid Sequence; Arylamine N-Acetyltransferase; Base Sequence; Black People; Caffeine; Genotype; Humans; Molecular Sequence Data; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Sequence Homology, Amino Acid; United States; Uracil; Xanthines | 1993 |
HPLC method for rapid determination of acetylator phenotype by measuring urinary caffeine metabolites.
Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Phenotype; Reproducibility of Results; Uracil; Xanthines | 1993 |
A population and family study of N-acetyltransferase using caffeine urinary metabolites.
Topics: Acetylation; Arylamine N-Acetyltransferase; Caffeine; Family; Heterozygote; Humans; Models, Statistical; Time Factors; Uracil; Xanthines | 1993 |
Acetylator phenotype in patients with p-phenylenediamine allergy.
Topics: Acetylation; Biomarkers; Caffeine; Chromatography, High Pressure Liquid; Coloring Agents; Dermatitis, Contact; Environmental Exposure; Female; Hair Dyes; Humans; Irritants; Male; Patch Tests; Phenotype; Phenylenediamines; Risk Factors; Skin; Uracil; Xanthines | 1997 |
A case of malignant peritoneal mesothelioma showed complete remission with chemotherapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Caffeine; Cisplatin; Combined Modality Therapy; Drug Combinations; Etoposide; Female; Humans; Mesothelioma; Neoplasms, Unknown Primary; Peritoneal Neoplasms; Remission Induction; Tegafur; Uracil | 1998 |
Induction of fragile sites by fluorodeoxyuridine and caffeine accompanies with misincorpolation of endogenous uridine nucleotide into DNA of feline fibroblasts.
Topics: Animals; Caffeine; Cats; Cells, Cultured; Chromosome Fragile Sites; Chromosome Fragility; DNA; DNA Glycosylases; Female; Fibroblasts; Floxuridine; N-Glycosyl Hydrolases; Uracil; Uracil Nucleotides; Uracil-DNA Glycosidase | 1998 |
Five caffeine metabolite ratios to measure tobacco-induced CYP1A2 activity and their relationships with urinary mutagenicity and urine flow.
Topics: Adolescent; Adult; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 CYP1A2; Environmental Exposure; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mutagens; Rheology; Smoking; Theophylline; Time Factors; Uracil; Uric Acid; Urination; Xanthines | 1999 |
Induction of premature mitosis in S-blocked onion cells.
Topics: 2-Aminopurine; Antimetabolites; Caffeine; Cells, Cultured; Cyclin B; Cycloheximide; Drug Interactions; Enzyme Inhibitors; Meristem; Mitosis; Onions; Phosphorus Isotopes; Protein-Tyrosine Kinases; S Phase; Spindle Apparatus; Uracil | 1998 |
Caffeine metabolism before and after liver transplantation.
Topics: Adult; Aged; Aryl Hydrocarbon Hydroxylases; Azathioprine; Caffeine; Case-Control Studies; Cyclosporine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Female; Humans; Immunosuppressive Agents; Liver; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Mixed Function Oxygenases; Reference Values; Uracil; Xanthine Oxidase | 2001 |
Validity of an ELISA for N-acetyltransferase-2 (NAT2) phenotyping.
Topics: Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Genotype; Humans; Phenotype; Uracil; Xanthines | 2001 |
Extractionless method for the simultaneous high-performance liquid chromatographic determination of urinary caffeine metabolites for N-acetyltransferase 2, cytochrome P450 1A2 and xanthine oxidase activity assessment.
Topics: Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Humans; Models, Chemical; Reproducibility of Results; Uracil; Xanthine Oxidase | 2001 |
[Determination of caffeine metabolite for the evaluation of N-acetyltransferase, CYP1A2 and xanthine oxidase activities].
Topics: Adolescent; Adult; Aged; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Female; Humans; Male; Middle Aged; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines | 1997 |
[HPLC determination of five caffeine metabolites].
Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Theophylline; Uracil; Uric Acid; Xanthines | 1997 |
Relationship between metabolic phenotype of N-acetylation and bladder cancer.
Topics: Acetylation; Adult; Caffeine; Female; Humans; Male; Middle Aged; Phenotype; Uracil; Urinary Bladder Neoplasms; Xanthines | 2000 |
Severe 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) intoxication: insights into the measurement of hepatic cytochrome P450 1A2 induction.
Topics: Adult; Breath Tests; Caffeine; Case-Control Studies; Cytochrome P-450 CYP1A2; Environmental Pollutants; Enzyme Induction; Female; Humans; Liver; Male; Methylation; Polychlorinated Dibenzodioxins; Smoking; Teratogens; Theophylline; Uracil; Uric Acid; Xanthines | 2002 |
NAT2 and CYP1A2 phenotyping with caffeine: head-to-head comparison of AFMU vs. AAMU in the urine metabolite ratios.
Topics: Adult; Arylamine N-Acetyltransferase; Caffeine; Cytochrome P-450 CYP1A2; Female; Humans; Male; Middle Aged; Phenotype; Uracil | 2003 |
INTERACTION OF PURINES WITH THE PYRIMIDINE TRANSPORT PROCESS OF THE SMALL INTESTINE.
Topics: Adenine; Caffeine; Carbon Isotopes; Guanine; Intestine, Small; Intestines; Mercaptopurine; Pharmacology; Physiology; Purines; Pyrimidines; Rats; Research; Theobromine; Theophylline; Uracil; Uric Acid; Xanthines | 1963 |
THE DYE-SENSITIZED PHOTOOXIDATION OF PURINE AND PYRIMIDINE DERIVATIVES.
Topics: Caffeine; Guanine; Guanine Nucleotides; Hydrogen-Ion Concentration; Hypoxanthines; Infrared Rays; Light; Manometry; Methylene Blue; Nucleosides; Oxidation-Reduction; Purines; Research; Theobromine; Theophylline; Thymidine; Thymine; Ultraviolet Rays; Uracil; Uric Acid; Xanthines | 1964 |
INTERMOLECULAR FORCES IN ASSOCIATION OF PURINES WITH POLYBENZENOID HYDROCARBONS.
Topics: Adenine; Benzopyrenes; Caffeine; Chemical Phenomena; Chemistry; Cytosine; Guanine; Hypoxanthines; London; Purines; Pyrimidines; Research; Thymine; Uracil; Uric Acid; Xanthines | 1965 |
Phenotyping of N-acetyltransferase type 2 by caffeine from uncontrolled dietary exposure.
Topics: Acetylation; Administration, Oral; Adult; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Diet; Female; Genotype; Humans; Male; Middle Aged; Phenotype; Spectrometry, Mass, Electrospray Ionization; Time Factors; Uracil; Uric Acid; Xanthines | 2004 |
Re-investigation of the concordance of human NAT2 phenotypes and genotypes.
Topics: Acetylation; Alleles; Arylamine N-Acetyltransferase; Caffeine; Central Nervous System Stimulants; Genotype; Humans; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Uracil; Xanthines | 2005 |
DNA injury induced by 5-aminouracil and caffeine in G2 checkpoints path of higher plant cells.
Topics: Caffeine; Cell Nucleus; Chromosome Aberrations; DNA; DNA Damage; Dose-Response Relationship, Drug; G2 Phase; Garlic; Metaphase; Mitosis; Phosphodiesterase Inhibitors; Plants; Temperature; Time Factors; Uracil | 2005 |
[Determination of the activity of cytochrome P-450 CYP2A6 by HPLC method with caffeine as metabolizing probe].
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2A6; Female; Humans; Male; Mixed Function Oxygenases; Theophylline; Uracil; Uric Acid; Xanthines | 2006 |
Concordance between the deduced acetylation status generated by high-speed: real-time PCR based NAT2 genotyping of seven single nucleotide polymorphisms and human NAT2 phenotypes determined by a caffeine assay.
Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Biotransformation; Caffeine; Genotype; Humans; Male; Middle Aged; Phenotype; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Uracil; Uric Acid; White People; Xanthines | 2007 |
Caffeine N3-demethylation (CYP1A2) in a population with an increased exposure to polychlorinated biphenyls.
Topics: Administration, Oral; Adolescent; Adult; Biometry; Caffeine; Cohort Studies; Cytochrome P-450 CYP1A2; Environmental Pollutants; Female; Genotype; Humans; Male; Methylation; Middle Aged; Polychlorinated Biphenyls; Sex Factors; Smoking; Uracil; Uric Acid; Xanthines | 2006 |
In vivo evaluation of CYP1A2, CYP2A6, NAT-2 and xanthine oxidase activities in a Greek population sample by the RP-HPLC monitoring of caffeine metabolic ratios.
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Female; Humans; Male; Middle Aged; Mixed Function Oxygenases; Reproducibility of Results; Sensitivity and Specificity; Smoking; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines | 2007 |
Phenotyping of N-acetyltransferase type 2 and xanthine oxidase with caffeine: when should urine samples be collected?
Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Caffeine; Central Nervous System Stimulants; Humans; Male; Phenotype; Time Factors; Uracil; Uric Acid; White People; Xanthine Oxidase; Xanthines | 2009 |
Inhibitory effects of caffeine and its metabolites on intracellular lipid accumulation in murine 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Obesity Agents; Biological Transport; Caffeine; Cell Differentiation; Glucose; Insulin; Lipid Metabolism; Mice; Theophylline; Uracil; Uric Acid; Xanthines | 2008 |
N-Acetyltransferase-2 (NAT2) gene polymorphisms and enzyme activity in Serbs: unprecedented high prevalence of rapid acetylators in a White population.
Topics: Acetylation; Adolescent; Adult; Arylamine N-Acetyltransferase; Caffeine; Female; Genetic Association Studies; Haplotypes; Humans; Isoenzymes; Male; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Serbia; Uracil; Uric Acid; White People; Xanthines; Young Adult | 2011 |
Comparison of N-acetyltransferase-2 enzyme genotype-phenotype and xanthine oxidase enzyme activity between Swedes and Koreans.
Topics: Arylamine N-Acetyltransferase; Asian People; Caffeine; Contraceptives, Oral; Genotype; Humans; Phenotype; Polymorphism, Single Nucleotide; Sex Factors; Uracil; Uric Acid; White People; Xanthine Oxidase; Xanthines | 2012 |
[Effect of Tibetan medicine zuotai on the activity, protein and mRNA expression of CYP1A2 and NAT2].
Topics: Administration, Oral; Animals; Arylamine N-Acetyltransferase; Caffeine; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Male; Medicine, Tibetan Traditional; Rats; Rats, Sprague-Dawley; RNA, Messenger; Theophylline; Uracil; Uric Acid; Xanthines | 2014 |
Urine excretion of caffeine and select caffeine metabolites is common in the U.S. population and associated with caffeine intake.
Topics: Adolescent; Adult; Biomarkers; Black or African American; Caffeine; Child; Chromatography, Liquid; Cross-Sectional Studies; Female; Hispanic or Latino; Humans; Male; Middle Aged; Nutrition Surveys; Tandem Mass Spectrometry; Theophylline; Uracil; Uric Acid; White People; Xanthines; Young Adult | 2015 |
Palladium-catalyzed C-H olefination of uracils and caffeines using molecular oxygen as the sole oxidant.
Topics: Caffeine; Carbon; Catalysis; Hydrogen; Oxidants; Oxygen; Palladium; Uracil | 2017 |
N-Acetyltransferase-2 (NAT2) phenotype is influenced by genotype-environment interaction in Ethiopians.
Topics: Adult; Arylamine N-Acetyltransferase; Black People; Caffeine; Ethiopia; Female; Gene-Environment Interaction; Genotype; Humans; Male; Phenotype; Polymorphism, Single Nucleotide; Sweden; Uracil; Uric Acid; Xanthines | 2018 |
Serum Metabolome of Coffee Consumption and its Association With Bone Mineral Density: The Hong Kong Osteoporosis Study.
Topics: Absorptiometry, Photon; Alkaloids; Bone Density; Caffeine; Coffee; Diet Surveys; Drinking; Female; Femur Neck; Hippurates; Hong Kong; Humans; Independent Living; Linear Models; Lumbar Vertebrae; Male; Metabolome; Middle Aged; Osteoporosis; Prospective Studies; Uracil | 2020 |