Compounds > caffeine

caffeine and troleandomycin

caffeine has been researched along with troleandomycin in 7 studies

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (28.57)	18.2507
2000's	1 (14.29)	29.6817
2010's	4 (57.14)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Batzias, J; Horbach, GJ; Maas, RF; van Miert, AS; Witkamp, RF; Zweers-Zeilmaker, WM	1
Fujita, S; Funae, Y; Imaoka, S; Kazusaka, A; Maeda, Y; Masuda, M; Morita, K	1
Bement, J; Chatfield, K; DiPetrillo, K; Jeffery, E; Kostrubsky, V; Sinclair, J; Sinclair, P; Wood, S; Wrighton, S	1

Other Studies

7 other study(ies) available for caffeine and troleandomycin

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
In vitro and in vivo oxidative biotransformation in the West-African dwarf goat (Caprus hircus aegagrus): substrate activities and effects of inducers. Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:11 Topics: Animals; Antipyrine; beta-Naphthoflavone; Biotransformation; Blotting, Western; Caffeine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Goats; Isoniazid; Microsomes, Liver; Phenobarbital; Sulfamethazine; Troleandomycin	1996
Strain differences in CYP3A-mediated C-8 hydroxylation (1,3,7-trimethyluric acid formation) of caffeine in Wistar and Dark Agouti rats. Rapid metabolism of caffeine in debrisoquine poor metabolizer model rats. Biochemical pharmacology, 1998, May-01, Volume: 55, Issue:9 Topics: Aging; Animals; Aryl Hydrocarbon Hydroxylases; Caffeine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Debrisoquin; Dexamethasone; Female; Humans; Hydroxylation; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Wistar; Sex Characteristics; Species Specificity; Troleandomycin; Uric Acid	1998
Effect of caffeine on acetaminophen hepatotoxicity in cultured hepatocytes treated with ethanol and isopentanol. Toxicology and applied pharmacology, 2002, Dec-01, Volume: 185, Issue:2 Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Aryl Hydrocarbon Hydroxylases; Caffeine; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP3A; Drug Synergism; Enzyme Inhibitors; Ethanol; Hepatocytes; Oxidoreductases, N-Demethylating; Pentanols; Rats; Troleandomycin	2002