caffeine and trigonelline

caffeine has been researched along with trigonelline in 44 studies

Research

Studies (44)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (6.82)	18.7374
1990's	2 (4.55)	18.2507
2000's	6 (13.64)	29.6817
2010's	23 (52.27)	24.3611
2020's	10 (22.73)	2.80

Authors

Authors	Studies
Macrae, R; Trugo, LC	1
Spiller, MA	1
Maier, HG; Stennert, A	2
Alves, MR; Casal, S; Ferreira, MA; Oliveira, MB	1
Andueza, S; Bello, J; Cid, C; Ibañez, C; Maeztu, L; Paz de Peña, M	1
KREMERS, RE	1
Hong, BN; Kang, TH; Kim, SY; Park, R; Yi, TH	1
Akashi, I; Hirano, T; Kagami, K; Oka, K	1
Heine, RJ; Meeuse, JC; Olthof, MR; Seebus, E; van Dam, RM; van Dijk, AE	1
Hong, BN; Kang, TH; Kim, SY; Yi, TH	1
Berregi, I; Caracena, R; del Campo, G; Zuriarrain, J	1
Azevedo, L; Brigagão, MR; Carvalho, Ddo C; de Paula, FB; dos Santos, MH; Giusti-Paiva, A	1
Mueller, U; Pichner, R; Pischetsrieder, M; Sauer, T; Weigel, I	1
Bicho, NC; De Alvarenga, NB; Leitão, AE; Lidon, FC; Ramalho, JC	1
Hofmann, T; Lang, R; Rubach, M; Seebach, E; Somoza, MM; Somoza, V	1
Beusch, A; Dieminger, N; Dunkel, A; Hauner, H; Hofmann, T; Lang, R; Lee, YM; Skurk, T; Suess, B; Wahl, A	1
Beusch, A; Bytof, G; Dieminger, N; Dunkel, A; Eggers, R; Hofmann, T; Lang, R; Lantz, I; Stiebitz, H; Wahl, A; Yagar, EF	1
Caprioli, G; Cortese, M; Maggi, F; Minnetti, C; Odello, L; Sagratini, G; Vittori, S	1
Bytof, G; Hofmann, T; Lang, R; Lantz, I; Rubach, M; Somoza, V; Stiebitz, H	1
Ashihara, H; Clifford, MN; Crozier, A; Lean, ME; Ludwig, IA	1
Bakuradze, T; Eisenbrand, G; Galan, J; Hofmann, T; Lang, R; Richling, E; Schipp, D	2
Buscemi, S; Galvano, F; Godos, J; Grosso, G; Li Volti, G; Marventano, S; Pluchinotta, FR	1
Hong, BN; Ji, MG; Kang, TH; Kim, K; Kim, UJ; Nam, YH; Rodriguez, I	1
Aizawa, S; Arai, K; Kodama, S; Taga, A; Terashima, H; Tsutsumiuchi, K; Yamamoto, A	1
Furtado, A; Henry, RJ; Lee, LS; Smyth, H; Tran, HT	1
Bae, HJ; Cho, BK; Cho, JS; Moon, KD	1
Gerardo Zepeda, L; Serrano-Contreras, JI; Téllez-Medina, DI; Villalón-López, N	1
Airoldi, C; Ciaramelli, C; Palmioli, A	1
Chaiwarith, J; Horadee, S; Khampa, N; Rattanapanone, N; Wongsa, P	1
Barbisan, LF; Chaves, MAG; Cogliati, B; Moreno, FS; Rocha, AB; Romualdo, GR; Vinken, M	1
Bae, HJ; Cho, EJ; Funada, R; Nguyen, TMT; Oh, CH; Song, Y	1
Assi, N; Boeing, H; Boutron-Ruault, MC; Casagrande, C; Ferrari, P; Jenab, M; Katzke, V; Keski-Rahkonen, P; Krogh, V; Kühn, T; Mahamat-Saleh, Y; Mancini, FR; Mattiello, A; Niforou, K; Palli, D; Robinot, N; Rothwell, JA; Sacerdote, C; Scalbert, A; Trichopoulou, A; Tumino, R; Valanou, E	1
Au, PCM; Chau, YP; Cheng, VKF; Cheung, CL; Kung, AWC; Li, GHY; Sing, CW; Tan, KCB	1
Almeida da Fonseca, AF; da Cunha, PHP; Filgueiras, PR; Ifa, DR; Lemos, MF; Pereira, LL; Perez, C; Scherer, R	1
Hu, G; Li, X; Peng, X; Qiu, M; Wang, X	1
Koh, GH; Lee, T; Mok, C; Park, H; Puligundla, P; Yoon, J	1
de Abreu Pinheiro, F; de Jesus Filho, M; Ferreira Elias, L; Fumiere Lemos, M; Gomes Rocha, JC; Scherer, R; Soares Cardoso, W; Uliana Modolo, M	1
Barbisan, LF; Cogliati, B; da Silva, TC; Evangelista, AF; Moreno, FS; Prata, GB; Reis, RM; Romualdo, GR; Vinken, M	1
Batista, AM; Calado, V; Cruz, A; Cunha, SC; dePaula, J; Farah, A; Fernandes, JO; Revi, I; Sá, SVMD	1
Arunachalam, T; Berrué, F; Burton, IW; Martinez Farina, CF; Newmaster, S; Ragupathy, S	1
Chanthick, C; Peerapen, P; Thongboonkerd, V	1
Azevedo, LM; Bicalho, EM; Carvalho, GR; de Andrade, FHA; de Oliveira Santos, M; de Resende, MLV; Ferreira, AMO; Silva, VA	1

Reviews

5 review(s) available for caffeine and trigonelline

Article	Year
The chemical components of coffee. Progress in clinical and biological research, 1984, Volume: 158 Topics: Alkaloids; Caffeine; Carbohydrates; Coffee; Hydrocarbons; Lipids; Mycotoxins; Nitrogen; Pesticides; Phenols; Sulfur; Theobromine; Theophylline; Vitamins	1984
Coffee: biochemistry and potential impact on health. Food & function, 2014, Volume: 5, Issue:8 Topics: Alkaloids; Animals; Antioxidants; Caffeine; Cardiovascular Diseases; Chlorogenic Acid; Coffee; Diabetes Mellitus, Type 2; Disease Models, Animal; Diterpenes; Humans; Maillard Reaction; Meta-Analysis as Topic; Neoplasms; Parkinson Disease; Polymers	2014
Coffee components and cardiovascular risk: beneficial and detrimental effects. International journal of food sciences and nutrition, 2014, Volume: 65, Issue:8 Topics: Alkaloids; Caffeine; Cardiovascular Diseases; Cardiovascular System; Chlorogenic Acid; Coffee; Diabetes Mellitus, Type 2; Diterpenes; Humans; Plant Extracts; Polymers; Polyphenols	2014
Advances in genomics for the improvement of quality in coffee. Journal of the science of food and agriculture, 2016, Volume: 96, Issue:10 Topics: Alkaloids; Caffeine; Coffea; Coffee; Food Quality; Gene Library; Genes, Plant; Genomics; Genotype; Lipids; Quantitative Trait Loci; Seeds; Sequence Analysis; Sucrose	2016
Drinking for protection? Epidemiological and experimental evidence on the beneficial effects of coffee or major coffee compounds against gastrointestinal and liver carcinogenesis. Food research international (Ottawa, Ont.), 2019, Volume: 123 Topics: Alkaloids; Caffeine; Carcinogenesis; Chlorogenic Acid; Coffea; Coffee; Gastrointestinal Neoplasms; Gastrointestinal Tract; Humans; Liver; Liver Neoplasms; Meta-Analysis as Topic	2019

Trials

4 trial(s) available for caffeine and trigonelline

Article	Year
Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on glucose tolerance. Diabetes care, 2009, Volume: 32, Issue:6 Topics: Alkaloids; Blood Glucose; Caffeine; Chlorogenic Acid; Coffee; Cross-Over Studies; Glucose Tolerance Test; Humans; Insulin; Male; Mannitol; Overweight; Placebos	2009
A dark brown roast coffee blend is less effective at stimulating gastric acid secretion in healthy volunteers compared to a medium roast market blend. Molecular nutrition & food research, 2014, Volume: 58, Issue:6 Topics: Adult; Alkaloids; Caffeine; Chlorogenic Acid; Chromatography, High Pressure Liquid; Coffee; Double-Blind Method; Female; Gastric Acid; Healthy Volunteers; Humans; Hydrogen-Ion Concentration; Male; Niacinamide; Pyridinium Compounds; Tandem Mass Spectrometry; Tryptamines; Young Adult	2014
Consumption of a dark roast coffee decreases the level of spontaneous DNA strand breaks: a randomized controlled trial. European journal of nutrition, 2015, Volume: 54, Issue:1 Topics: Adult; Alkaloids; Antioxidants; Biomarkers; Caffeine; Coffea; Coffee; Cohort Studies; Comet Assay; DNA Breaks; Food Handling; Germany; Hot Temperature; Humans; Leukocytes; Male; Patient Compliance; Pyridinium Compounds; Quinic Acid; Seeds	2015
Coffee consumption rapidly reduces background DNA strand breaks in healthy humans: Results of a short-term repeated uptake intervention study. Molecular nutrition & food research, 2016, Volume: 60, Issue:3 Topics: Adult; Alkaloids; Caffeine; Coffee; Comet Assay; DNA Damage; Humans; Male; Middle Aged	2016

Other Studies

35 other study(ies) available for caffeine and trigonelline

Article	Year
Application of high performance liquid chromatography to the analysis of some non-volatile coffee components. Archivos latinoamericanos de nutricion, 1989, Volume: 39, Issue:1 Topics: Alkaloids; Caffeine; Chromatography, High Pressure Liquid; Coffee; Food Handling; Food Technology; Hot Temperature; Nicotinic Acids; Sucrose	1989
Trigonelline in coffee. II. Content of green, roasted and instant coffee. Zeitschrift fur Lebensmittel-Untersuchung und -Forschung, 1994, Volume: 199, Issue:3 Topics: Alkaloids; Caffeine; Coffee; Food Analysis; Food Handling; Hot Temperature; Species Specificity	1994
[Trigonelline in coffee. I. Comparison of thin layer chromatography with high-performance liquid chromatography. Simultaneous determination of caffeine]. Zeitschrift fur Lebensmittel-Untersuchung und -Forschung, 1993, Volume: 196, Issue:5 Topics: Alkaloids; Caffeine; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Coffee; Reproducibility of Results	1993
Discriminate analysis of roasted coffee varieties for trigonelline, nicotinic acid, and caffeine content. Journal of agricultural and food chemistry, 2000, Volume: 48, Issue:8 Topics: Alkaloids; Caffeine; Chromatography, High Pressure Liquid; Coffee; Niacin	2000
Multivariate methods for characterization and classification of espresso coffees from different botanical varieties and types of roast by foam, taste, and mouthfeel. Journal of agricultural and food chemistry, 2001, Volume: 49, Issue:10 Topics: Alkaloids; Caffeine; Chlorogenic Acid; Chromatography, High Pressure Liquid; Coffee; Discriminant Analysis; Hydrogen-Ion Concentration; Lipids; Multivariate Analysis; Sensation; Species Specificity; Taste	2001
Speculation on DPN as a biochemical precursor of caffeine and trigonelline in coffee. Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1954, Volume: 43, Issue:7 Topics: Alkaloids; Caffeine; Coenzymes; Coffee; NAD; Niacin; Nicotinic Acids	1954
Coffee improves auditory neuropathy in diabetic mice. Neuroscience letters, 2008, Aug-29, Volume: 441, Issue:3 Topics: Acoustic Stimulation; Alkaloids; Animals; Auditory Pathways; Auditory Threshold; Caffeine; Cochlear Nerve; Coffee; Cranial Nerve Diseases; Diabetes Mellitus, Experimental; Disease Models, Animal; Evoked Potentials, Auditory, Brain Stem; Hearing Loss, Sensorineural; Male; Mice; Mice, Inbred ICR; Neural Conduction; Phosphodiesterase Inhibitors; Reaction Time	2008
Protective effects of coffee-derived compounds on lipopolysaccharide/D-galactosamine induced acute liver injury in rats. The Journal of pharmacy and pharmacology, 2009, Volume: 61, Issue:4 Topics: Alanine Transaminase; Alkaloids; Animals; Aspartate Aminotransferases; Caffeine; Chemical and Drug Induced Liver Injury; Chlorogenic Acid; Coffee; Galactosamine; Interleukin-10; Lipopolysaccharides; Liver Diseases; Male; Niacin; Pyrazinamide; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha	2009
High-dosage pyridoxine-induced auditory neuropathy and protection with coffee in mice. Biological & pharmaceutical bulletin, 2009, Volume: 32, Issue:4 Topics: Alkaloids; Animals; Auditory Pathways; Caffeine; Cochlea; Cochlear Nerve; Coffee; Evoked Potentials, Auditory; Evoked Potentials, Auditory, Brain Stem; Male; Mice; Mice, Inbred ICR; Peripheral Nervous System Diseases; Plant Extracts; Pyridoxine; Vitamins	2009
Quantitative determination of caffeine, formic acid, trigonelline and 5-(hydroxymethyl)furfural in soluble coffees by 1H NMR spectrometry. Talanta, 2010, Apr-15, Volume: 81, Issue:1-2 Topics: Alkaloids; Caffeine; Calibration; Coffee; Food Analysis; Formates; Furaldehyde; Limit of Detection; Magnetic Resonance Spectroscopy; Solubility; Solutions; Time Factors	2010
Organic and conventional Coffea arabica L.: a comparative study of the chemical composition and physiological, biochemical and toxicological effects in Wistar rats. Plant foods for human nutrition (Dordrecht, Netherlands), 2011, Volume: 66, Issue:2 Topics: Alkaloids; Animals; Anticarcinogenic Agents; Antioxidants; Behavior, Animal; Body Weight; Caffeine; Chlorogenic Acid; Coffea; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Lipid Peroxidation; Male; Malondialdehyde; Mucins; Organic Agriculture; Oxidative Stress; Precancerous Conditions; Protein Carbonylation; Rats; Rats, Wistar	2011
Identification of H₂O₂ as a major antimicrobial component in coffee. Food & function, 2011, Volume: 2, Issue:5 Topics: Alkaloids; Anti-Infective Agents; Caffeine; Chlorogenic Acid; Coffee; Coumaric Acids; Culture Media; Escherichia coli; Furaldehyde; Hydrogen Peroxide; Listeria; Lysine; Plant Extracts; Ribose; Temperature	2011
Identification of nutritional descriptors of roasting intensity in beverages of Arabica and Robusta coffee beans. International journal of food sciences and nutrition, 2011, Volume: 62, Issue:8 Topics: Alkaloids; Caffeine; Chlorogenic Acid; Coffea; Coffee; Cooking; Coumaric Acids; Hot Temperature; Hydrogen-Ion Concentration; Plant Extracts; Quinic Acid; Seeds; Solubility; Species Specificity	2011
Multi-parametric approach to identify coffee components that regulate mechanisms of gastric acid secretion. Molecular nutrition & food research, 2012, Volume: 56, Issue:2 Topics: Activating Transcription Factor 2; Alkaloids; Caffeine; Catechols; Cell Line, Tumor; Chlorogenic Acid; Coffee; Cyclic AMP; Down-Regulation; Drug Synergism; Gastric Acid; Gene Expression Regulation; H(+)-K(+)-Exchanging ATPase; Humans; Parietal Cells, Gastric; Protons; Pyridinium Compounds; Pyrogallol; Receptors, Somatostatin	2012
Bioappearance and pharmacokinetics of bioactives upon coffee consumption. Analytical and bioanalytical chemistry, 2013, Volume: 405, Issue:26 Topics: Adult; Alkaloids; Caffeine; Chlorogenic Acid; Coffee; Coumaric Acids; Female; Humans; Male; Tandem Mass Spectrometry; Xanthines; Young Adult	2013
Quantitative studies on roast kinetics for bioactives in coffee. Journal of agricultural and food chemistry, 2013, Dec-11, Volume: 61, Issue:49 Topics: Alkaloids; Caffeine; Coffea; Cooking; Kinetics; Pyridinium Compounds; Quinic Acid; Seeds	2013
Quantification of caffeine, trigonelline and nicotinic acid in espresso coffee: the influence of espresso machines and coffee cultivars. International journal of food sciences and nutrition, 2014, Volume: 65, Issue:4 Topics: Alkaloids; Caffeine; Chromatography, High Pressure Liquid; Coffea; Coffee; Cooking and Eating Utensils; Food Inspection; Food Quality; Food-Processing Industry; Hot Temperature; Hydrostatic Pressure; Italy; Niacin; Reproducibility of Results; Seeds; Spectrophotometry	2014
Synergistic Potentials of Coffee on Injured Pancreatic Islets and Insulin Action via KATP Channel Blocking in Zebrafish. Journal of agricultural and food chemistry, 2015, Jun-17, Volume: 63, Issue:23 Topics: Alkaloids; Alloxan; Animals; Caffeine; Chlorogenic Acid; Coffea; Coffee; Drug Synergism; Insulin; Islets of Langerhans; KATP Channels; Plant Extracts; Zebrafish	2015
Simultaneous Determination of Trigonelline, Caffeine, Chlorogenic Acid and Their Related Compounds in Instant Coffee Samples by HPLC Using an Acidic Mobile Phase Containing Octanesulfonate. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2015, Volume: 31, Issue:8 Topics: Alkaloids; Alkanesulfonic Acids; Caffeine; Chlorogenic Acid; Chromatography, High Pressure Liquid; Coffee; Time Factors	2015
Qualitative properties of roasting defect beans and development of its classification methods by hyperspectral imaging technology. Food chemistry, 2017, Apr-01, Volume: 220 Topics: Alkaloids; Caffeine; Chlorogenic Acid; Coffea; Cooking; Discriminant Analysis; Hot Temperature; Image Processing, Computer-Assisted; Least-Squares Analysis	2017
An Food research international (Ottawa, Ont.), 2018, Volume: 106 Topics: Alkaloids; Caffeine; Carbohydrates; Coffea; Coffee; Desiccation; Food Handling; Freeze Drying; Furaldehyde; Hot Temperature; Magnetic Resonance Spectroscopy; Metabolomics; Quinic Acid; Seeds	2018
Coffee variety, origin and extraction procedure: Implications for coffee beneficial effects on human health. Food chemistry, 2019, Apr-25, Volume: 278 Topics: Alkaloids; Antioxidants; Caffeine; Chlorogenic Acid; Coffea; Coffee; Humans; Magnetic Resonance Spectroscopy; Polymers; Principal Component Analysis; Seeds; Sonication	2019
Quality and bioactive compounds of blends of Arabica and Robusta spray-dried coffee. Food chemistry, 2019, Jun-15, Volume: 283 Topics: Alkaloids; Caffeine; Coffea; Coffee; Desiccation; Gas Chromatography-Mass Spectrometry; Magnetic Resonance Spectroscopy; Phytochemicals; Quinic Acid; Seeds; Volatile Organic Compounds	2019
Use of coffee flower as a novel resource for the production of bioactive compounds, melanoidins, and bio-sugars. Food chemistry, 2019, Nov-30, Volume: 299 Topics: Alkaloids; Antioxidants; Caffeine; Carbohydrates; Coffea; Flowers; Phenols; Phytochemicals; Polymers; Sugars	2019
A Metabolomic Study of Biomarkers of Habitual Coffee Intake in Four European Countries. Molecular nutrition & food research, 2019, Volume: 63, Issue:22 Topics: Adult; Aged; Alkaloids; Biomarkers; Caffeine; Coffee; Europe; Female; Humans; Male; Metabolomics; Middle Aged; Prospective Studies; Theophylline	2019
Serum Metabolome of Coffee Consumption and its Association With Bone Mineral Density: The Hong Kong Osteoporosis Study. The Journal of clinical endocrinology and metabolism, 2020, 03-01, Volume: 105, Issue:3 Topics: Absorptiometry, Photon; Alkaloids; Bone Density; Caffeine; Coffee; Diet Surveys; Drinking; Female; Femur Neck; Hippurates; Hong Kong; Humans; Independent Living; Linear Models; Lumbar Vertebrae; Male; Metabolome; Middle Aged; Osteoporosis; Prospective Studies; Uracil	2020
Chemical and sensory profile of new genotypes of Brazilian Coffea canephora. Food chemistry, 2020, Apr-25, Volume: 310 Topics: Alkaloids; Brazil; Caffeine; Coffea; Genes, Plant; Genotype; Quinic Acid; Seeds; Spectrometry, Mass, Electrospray Ionization	2020
Excavation of coffee maturity markers and further research on their changes in coffee cherries of different maturity. Food research international (Ottawa, Ont.), 2020, Volume: 132 Topics: Alkaloids; Caffeine; Coffea; Coffee; Least-Squares Analysis; Magnetic Resonance Spectroscopy; Plant Extracts; Quinic Acid; Seeds	2020
Degradation of benzopyrene and acrylamide in roasted coffee beans by corona discharge plasma jet (CDPJ) and its effects on biochemical and sensory properties. Food chemistry, 2020, Oct-30, Volume: 328 Topics: Acrylamide; Alkaloids; Benzopyrenes; Biochemical Phenomena; Caffeine; Chlorogenic Acid; Coffee; Cooking; Electronic Nose; Hot Temperature	2020
Arabica and Conilon coffee flowers: Bioactive compounds and antioxidant capacity under different processes. Food chemistry, 2021, Jan-30, Volume: 336 Topics: Alkaloids; Antioxidants; Caffeine; Chlorogenic Acid; Chromatography, High Pressure Liquid; Coffea; Flowers; Freeze Drying; Phenols; Plant Extracts	2021
The combination of coffee compounds attenuates early fibrosis-associated hepatocarcinogenesis in mice: involvement of miRNA profile modulation. The Journal of nutritional biochemistry, 2020, Volume: 85 Topics: Alkaloids; Animals; Anticarcinogenic Agents; Caffeine; Carcinoma, Hepatocellular; Cell Line, Tumor; Chlorogenic Acid; Gene Expression Regulation, Neoplastic; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Mice, Inbred C3H; MicroRNAs; Transcriptome	2020
Contents of key bioactive and detrimental compounds in health performance coffees compared to conventional types of coffees sold in the United States market. Food & function, 2020, Sep-23, Volume: 11, Issue:9 Topics: Alkaloids; Antioxidants; Caffeine; Chlorogenic Acid; Chromatography, High Pressure Liquid; Coffea; Coffee; Humans; Plant Preparations; United States	2020
Quantitative NMR Methodology for the Authentication of Roasted Coffee and Prediction of Blends. Journal of agricultural and food chemistry, 2020, Dec-09, Volume: 68, Issue:49 Topics: Alkaloids; Caffeine; Coffea; Coffee; Cooking; Discriminant Analysis; Diterpenes; Food Contamination; Magnetic Resonance Spectroscopy; Seeds	2020
Quantitative proteomics reveals common and unique molecular mechanisms underlying beneficial effects of caffeine and trigonelline on human hepatocytes. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 158 Topics: Caffeine; Coffee; Hepatocytes; Humans; Proteomics; Tandem Mass Spectrometry	2023
IBA and melatonin increase trigonelline and caffeine during the induction and initiation of adventitious roots in Coffea arabica L. cuttings. Scientific reports, 2023, 09-13, Volume: 13, Issue:1 Topics: Antioxidants; Caffeine; Coffea; Hydrogen Peroxide; Melatonin; Phenols	2023