caffeine and thioridazine

caffeine has been researched along with thioridazine in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199010 (38.46)18.7374
1990's2 (7.69)18.2507
2000's6 (23.08)29.6817
2010's7 (26.92)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Sen, S; Sinha, N1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF1
Hollister, LE1
Amobi, N; Smith, IC1
Busca, GP1
Messerich, J1
Wohlzogen, FX2
Karapandzic, M; Obradovic, V; Piscevic, A; Poznic, M1
Senault, B1
Lialiaris, TS; Pantazaki, AA1
TURI, P1
RUDOLPH, AS; SEWELL, HH; WHITE, RP1

Reviews

3 review(s) available for caffeine and thioridazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells

2022
Drugs and sexual behavior in man.
    Life sciences, 1975, Sep-01, Volume: 17, Issue:5

    Topics: Amyl Nitrite; Barbiturates; Caffeine; Cannabis; Erectile Dysfunction; Ethanol; Gonadal Steroid Hormones; Humans; Levodopa; Lithium; Male; Nicotine; Opium; Sexual Behavior; Thioridazine

1975

Trials

4 trial(s) available for caffeine and thioridazine

ArticleYear
[EMA 3--a phenacetin-free combination with analgesic action].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1973, Jun-12, Volume: 62, Issue:24

    Topics: Acetaminophen; Adult; Aged; Allyl Compounds; Analgesics; Barbiturates; Caffeine; Clinical Trials as Topic; Drug Combinations; Evaluation Studies as Topic; Female; Headache; Humans; Male; Middle Aged; Migraine Disorders; Pain; Phenacetin; Thioridazine

1973
Method, design, and analysis of a comparative study of analgetics.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1970, Volume: 3, Issue:4

    Topics: Acetaminophen; Analgesics; Analysis of Variance; Caffeine; Clinical Trials as Topic; Humans; Pain; Placebos; Reaction Time; Thioridazine

1970
Method, design, and analysis of a comparative study of analgetics.
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1970, Volume: 4, Issue:4

    Topics: Acetaminophen; Analgesics; Analysis of Variance; Caffeine; Clinical Trials as Topic; Humans; Pain; Placebos; Reaction Time; Thioridazine

1970
[EMA 3--a new combined analgesic].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1970, Aug-18, Volume: 59, Issue:33

    Topics: Acetaminophen; Adult; Aged; Analgesics; Caffeine; Clinical Trials as Topic; Female; Humans; Male; Middle Aged; Thioridazine

1970

Other Studies

19 other study(ies) available for caffeine and thioridazine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Paradoxical effects of thioridazine on electromechanical coupling in the human and rat vas deferens.
    European journal of pharmacology, 1991, Jan-17, Volume: 192, Issue:3

    Topics: Animals; Biomechanical Phenomena; Caffeine; Calcimycin; Calcium Channel Blockers; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Rats; Thioridazine; Vas Deferens; Verapamil

1991
[Psychopharmacologic agents and the sense of smell].
    Monatsschrift fur Ohrenheilkunde und Laryngo-Rhinologie, 1968, Volume: 102, Issue:4

    Topics: Amphetamine; Antidepressive Agents; Bromine; Caffeine; Central Nervous System Stimulants; Chlordiazepoxide; Humans; Imipramine; Meclofenoxate; Meprobamate; Methylphenidate; Phenothiazines; Smell; Thioridazine; Tranquilizing Agents

1968
[Intraspecific aggressive behavior induced by apomorphine in the rat].
    Psychopharmacologia, 1970, Volume: 18, Issue:3

    Topics: Acepromazine; Age Factors; Aggression; Amitriptyline; Animals; Apomorphine; Atropine; Behavior, Animal; Caffeine; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Diazepam; Drug Antagonism; Electroshock; Environment; Haloperidol; Humans; Hydroxyzine; Imipramine; Male; Meprobamate; Morphine; Rats; Reserpine; Sex Factors; Sound; Species Specificity; Thiazines; Thioridazine

1970
A combined biochemical and cytogenetic study of thioridazine-induced damage to nucleic acids.
    Mutagenesis, 1999, Volume: 14, Issue:2

    Topics: Caffeine; Cells, Cultured; Deoxyribonuclease BamHI; DNA Restriction Enzymes; Humans; Lymphocytes; Melphalan; Mutagenicity Tests; Nucleic Acids; Sister Chromatid Exchange; Thioridazine

1999
ASSAY PROCEDURE FOR PHARMACEUTICAL COMBINATIONS OF ASPIRIN, PHENACETIN, CAFFEINE, AND ITOBARBITAL WITH PHENOTHIAZINE DERIVATIVES. I.
    Journal of pharmaceutical sciences, 1964, Volume: 53

    Topics: Anti-Bacterial Agents; Antipsychotic Agents; Aspirin; Barbiturates; Caffeine; Chemistry, Pharmaceutical; Chlorpromazine; Phenacetin; Phenothiazines; Promethazine; Research; Thiethylperazine; Thioridazine

1964
DRUG-INDUCED DISSOCIATION BETWEEN EVOKED RETICULAR POTENTIALS AND THE EEG.
    Electroencephalography and clinical neurophysiology, 1965, Volume: 19

    Topics: Amphetamine; Amphetamines; Animals; Antidepressive Agents; Atropine; Brain; Caffeine; Catechols; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Electroencephalography; Electrophysiology; Hallucinogens; Humans; Imipramine; Methamphetamine; Methylphenidate; Paraldehyde; Pentobarbital; Pentylenetetrazole; Phenoxybenzamine; Rabbits; Research; Reticular Formation; Scopolamine; Thioridazine; Tranquilizing Agents

1965