caffeine and sumatriptan

caffeine has been researched along with sumatriptan in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (10.00)18.2507
2000's19 (47.50)29.6817
2010's16 (40.00)24.3611
2020's1 (2.50)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Lombardo, F; Obach, RS; Waters, NJ1
Ahman, M; Holmén, AG; Wan, H1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Anaya Ordóñez, S; Matas Hoces, A1
Guanci, R; Lilley, LL1
Boan, JA; Evans, JL; Evans, KW; Shuaib, A1
Buurma, H; Egberts, AC; Leufkens, HG; Rahimtoola, H; Tijssen, CC1
Aloisio, A; Del Bianco, P; Di Monda, V; Fonzari, M; Grazioli, I; Nicolodi, M; Sicuteri, F; Uslenghi, C; Vecchiet, L1
Galeotti, N; Ghelardini, C; Grazioli, I; Uslenghi, C1
Hay, JW; Zhang, L1
Baggish, J; Battikha, JP; Elkind, AH; Gallagher, RM; Goldstein, J; Hoffman, H; Saper, JR; Silberstein, SD; Smith, TR1
Blumenthal, HJ; Diamond, ML1
Wenzel, RG1
Haag, G1
Cerbo, R; Del Bene, E; Ferrari, A; Genco, S; Grazioli, I; Martelletti, P; Nappi, G; Pinessi, L; Sandrini, G; Sarchielli, P; Tamburro, P; Uslenghi, C; Zanchin, G1
Galeotti, N; Ghelardini, C; Grazioli, I; Uslenghi, C; Vivoli, E1
Basurto Ona, X; Bonfill Cosp, X; Martínez García, L; Solà, I1
Derry, CJ; Derry, S; Moore, RA1
Hunter, BR; Seupaul, RA1
Cainazzo, M; Ciccarese, M; Guerzoni, S; Livrea, P; Pini, LA; Prudenzano, MP1
Fox, AW1
Micov, AM; Pecikoza, UB; Popović, BV; Stepanović-Petrović, RM; Tomić, MA1
Basurto Ona, X; Bonfill Cosp, X; Osorio, D1
Abu Bakar, MA; Baharuddin, KA; Norhayati, MN; Nurathirah, MN; Yazid, MB1

Reviews

8 review(s) available for caffeine and sumatriptan

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Cost-effectiveness analysis of rizatriptan and sumatriptan versus Cafergot in the acute treatment of migraine.
    CNS drugs, 2005, Volume: 19, Issue:7

    Topics: Caffeine; Cost-Benefit Analysis; Drug Combinations; Drug Therapy, Combination; Economics, Pharmaceutical; Ergotamine; Humans; Migraine Disorders; Serotonin Receptor Agonists; Sumatriptan; Triazoles; Tryptamines

2005
[Self-medication of migraine and headache].
    MMW Fortschritte der Medizin, 2006, Nov-23, Volume: 148, Issue:47

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Central Nervous System Stimulants; Controlled Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Evaluation Studies as Topic; Humans; Ibuprofen; Migraine Disorders; Practice Guidelines as Topic; Self Medication; Serotonin Receptor Agonists; Sumatriptan; Tablets; Tension-Type Headache; Vasoconstrictor Agents

2006
Drug therapy for treating post-dural puncture headache.
    The Cochrane database of systematic reviews, 2011, Aug-10, Issue:8

    Topics: Adrenocorticotropic Hormone; Amines; Analgesics; Caffeine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrocortisone; Male; Pain Measurement; Post-Dural Puncture Headache; Randomized Controlled Trials as Topic; Spinal Puncture; Sumatriptan; Theophylline; Treatment Outcome

2011
Sumatriptan (rectal route of administration) for acute migraine attacks in adults.
    The Cochrane database of systematic reviews, 2012, Feb-15, Issue:2

    Topics: Acute Disease; Administration, Rectal; Adult; Caffeine; Ergotamine; Female; Humans; Male; Migraine Disorders; Pain Management; Randomized Controlled Trials as Topic; Serotonin 5-HT1 Receptor Agonists; Sumatriptan

2012
Are there pharmacologic agents that safely and effectively treat post-lumbar puncture headache?
    Annals of emergency medicine, 2013, Volume: 61, Issue:1

    Topics: Adrenocorticotropic Hormone; Caffeine; Central Nervous System Stimulants; Headache; Humans; Injections, Intramuscular; Injections, Intravenous; Pain, Postoperative; Spinal Puncture; Sumatriptan; Treatment Outcome; Vasoconstrictor Agents

2013
Drug therapy for treating post-dural puncture headache.
    The Cochrane database of systematic reviews, 2015, Jul-15, Issue:7

    Topics: Adrenocorticotropic Hormone; Adult; Amines; Analgesics; Blood Patch, Epidural; Caffeine; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Hydrocortisone; Male; Middle Aged; Pain Measurement; Post-Dural Puncture Headache; Randomized Controlled Trials as Topic; Spinal Puncture; Sumatriptan; Theophylline; Treatment Outcome

2015
Efficacy of ketorolac in the treatment of acute migraine attack: A systematic review and meta-analysis.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2022, Volume: 29, Issue:9

    Topics: Caffeine; Dexamethasone; Diclofenac; Humans; Ketorolac; Metoclopramide; Migraine Disorders; Pain; Phenothiazines; Sumatriptan; Valproic Acid

2022

Trials

7 trial(s) available for caffeine and sumatriptan

ArticleYear
A randomized, double-blind comparison of sumatriptan and Cafergot in the acute treatment of migraine. The Multinational Oral Sumatriptan and Cafergot Comparative Study Group.
    European neurology, 1991, Volume: 31, Issue:5

    Topics: Administration, Oral; Adult; Aged; Caffeine; Double-Blind Method; Drug Combinations; Electrocardiography; Ergotamine; Female; Humans; Indoles; Male; Middle Aged; Migraine Disorders; Nausea; Recurrence; Sulfonamides; Sumatriptan; Vasoconstrictor Agents; Vomiting

1991
[Sumatriptan in the treatment of acute migraine: its role in primary health care].
    Atencion primaria, 1994, Apr-30, Volume: 13, Issue:7

    Topics: Acute Disease; Administration, Oral; Algorithms; Aspirin; Caffeine; Double-Blind Method; Drug Therapy, Combination; Ergotamine; Humans; Injections, Subcutaneous; Metoclopramide; Migraine Disorders; Recurrence; Sumatriptan

1994
Efficacy of a fixed combination of indomethacin, prochlorperazine, and caffeine versus sumatriptan in acute treatment of multiple migraine attacks: a multicenter, randomized, crossover trial.
    Headache, 2003, Volume: 43, Issue:8

    Topics: Acute Disease; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Caffeine; Central Nervous System Stimulants; Cross-Over Studies; Drug Combinations; Female; Humans; Indomethacin; Male; Migraine Disorders; Prochlorperazine; Recurrence; Research Design; Serotonin Receptor Agonists; Sumatriptan; Suppositories; Treatment Outcome

2003
Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial.
    Headache, 2005, Volume: 45, Issue:8

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Central Nervous System Stimulants; Chi-Square Distribution; Double-Blind Method; Drug Combinations; Dyspepsia; Female; Humans; Male; Migraine Disorders; Nausea; Nonprescription Drugs; Prospective Studies; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome

2005
Efficacy of dosing and re-dosing of two oral fixed combinations of indomethacin, prochlorperazine and caffeine compared with oral sumatriptan in the acute treatment of multiple migraine attacks: a double-blind, double-dummy, randomised, parallel group, mu
    International journal of clinical practice, 2007, Volume: 61, Issue:8

    Topics: Administration, Oral; Adolescent; Adult; Analgesics; Caffeine; Double-Blind Method; Drug Combinations; Female; Humans; Indomethacin; Male; Middle Aged; Migraine Disorders; Prochlorperazine; Recurrence; Sumatriptan; Treatment Outcome

2007
Comparison of tolerability and efficacy of a combination of paracetamol + caffeine and sumatriptan in the treatment of migraine attack: a randomized, double-blind, double-dummy, cross-over study.
    The journal of headache and pain, 2012, Volume: 13, Issue:8

    Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Caffeine; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Migraine Disorders; Pain Measurement; Sumatriptan; Treatment Outcome; Vasoconstrictor Agents

2012
Efficacy, end points and eventualities: sumatriptan/naproxen versus butalbital/paracetamol/caffeine in the treatment of migraine.
    Expert review of clinical pharmacology, 2012, Volume: 5, Issue:5

    Topics: Acetaminophen; Barbiturates; Caffeine; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Endpoint Determination; Humans; Migraine Disorders; Naproxen; Severity of Illness Index; Sumatriptan; Treatment Outcome

2012

Other Studies

25 other study(ies) available for caffeine and sumatriptan

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
History lessons. This incident underscored the importance of a fundamental nursing activity: history-taking.
    The American journal of nursing, 1997, Volume: 97, Issue:4

    Topics: Caffeine; Contraindications; Drug Combinations; Drug Interactions; Drug Therapy; Ergotamine; Female; Humans; Medical History Taking; Medication Errors; Middle Aged; Migraine Disorders; Patient Admission; Serotonin Receptor Agonists; Sumatriptan

1997
Economic evaluation of oral sumatriptan compared with oral caffeine/ergotamine for migraine.
    PharmacoEconomics, 1997, Volume: 12, Issue:5

    Topics: Administration, Oral; Caffeine; Cost-Benefit Analysis; Ergotamine; Migraine Disorders; Sensitivity and Specificity; Sumatriptan; Vasoconstrictor Agents

1997
Patterns of ergotamine and sumatriptan use in the Netherlands from 1991 to 1997.
    Cephalalgia : an international journal of headache, 2001, Volume: 21, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Caffeine; Cohort Studies; Cyclizine; Drug Combinations; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization; Ergotamine; Female; Humans; Male; Middle Aged; Migraine Disorders; Netherlands; Practice Patterns, Physicians'; Serotonin Receptor Agonists; Sumatriptan

2001
Indomethacin, alone and combined with prochlorperazine and caffeine, but not sumatriptan, abolishes peripheral and central sensitization in in vivo models of migraine.
    The journal of pain, 2004, Volume: 5, Issue:8

    Topics: Animals; Caffeine; Disease Models, Animal; Drug Therapy, Combination; Indomethacin; Male; Mice; Migraine Disorders; Pain Measurement; Peripheral Nerves; Prochlorperazine; Sumatriptan; Trigeminal Nerve

2004
Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial--a comment.
    Headache, 2006, Volume: 46, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Central Nervous System Stimulants; Drug Combinations; Humans; Migraine Disorders; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan

2006
A comment on acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial.
    Headache, 2006, Volume: 46, Issue:2

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Central Nervous System Stimulants; Drug Combinations; Humans; Migraine Disorders; Randomized Controlled Trials as Topic; Serotonin Receptor Agonists; Sumatriptan

2006
The central analgesia induced by antimigraine drugs is independent from Gi proteins: superiority of a fixed combination of indomethacin, prochlorperazine and caffeine, compared to sumatriptan, in an in vivo model.
    The journal of headache and pain, 2009, Volume: 10, Issue:6

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Caffeine; Central Nervous System Stimulants; Cerebral Arteries; Disease Models, Animal; Dopamine Antagonists; Drug Combinations; Drug Evaluation, Preclinical; Drug Synergism; GTP-Binding Protein alpha Subunits, Gi-Go; Indomethacin; Male; Mice; Migraine Disorders; Prochlorperazine; Serotonin Receptor Agonists; Sumatriptan; Treatment Outcome

2009
The effects of levetiracetam, sumatriptan, and caffeine in a rat model of trigeminal pain: interactions in 2-component combinations.
    Anesthesia and analgesia, 2015, Volume: 120, Issue:6

    Topics: Analgesics; Animals; Behavior, Animal; Caffeine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Facial Neuralgia; Facial Pain; Formaldehyde; Levetiracetam; Male; Motor Activity; Nociception; Piracetam; Rats, Wistar; Sumatriptan; Time Factors; Trigeminal Nerve Diseases

2015