caffeine and rotenone

caffeine has been researched along with rotenone in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19903 (12.50)18.7374
1990's4 (16.67)18.2507
2000's7 (29.17)29.6817
2010's7 (29.17)24.3611
2020's3 (12.50)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Gaudemer, Y; Gautheron, D; Merouze, P1
Babcock, DF; First, NL; Lardy, HA1
Halangk, W; Kunz, WS1
Fassina, G1
Brambilla, L; Cantoni, O; Clementi, E; Guidarelli, A; Sciorati, C1
Brambilla, L; Cantoni, O; Clementi, E; Guidarelli, A1
Atkins, CM; Li, YP; Reid, MB; Sweatt, JD1
Combettes, L; Lompré, AM; Vallot, O1
Boron, WF; Bouyer, P; Zhou, Y1
Cheranov, SY; Jaggar, JH1
Belmonte, S; Morad, M1
Bradley, E; Hollywood, MA; McHale, NG; Sergeant, GP; Thornbury, KD1
Fathalla, AM; Moustafa, AA; Soliman, AM1
Brooks, N; Dreczkowski, G; Gallagher, IJ; Galloway, SD; Hamilton, DL; Jeromson, S; Pediani, JD; Shaw, A; Watterson, KR; Whalley, T1
Bandookwala, M; Khairnar, A; Sahu, AK; Sengupta, P; Sharma, M; Thakkar, D1
Baker, BA; Booth, FW; Childs, TE; Gladden, LB; Kavazis, AN; Mumford, PW; Osburn, SC; Parry, HA; Roberson, PA; Roberts, MD; Romero, MA; Schwartz, TS; Toedebusch, RG1
Borutaite, V; Jankeviciute, S; Svirskiene, N; Svirskis, G1
Adeyeye, TA; Babatunde, BR; Johnson, VF; Shallie, PD1
Adeyeye, TA; Babatunde, BR; Ehireme, SE; Shallie, PD1

Other Studies

24 other study(ies) available for caffeine and rotenone

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Effects of catecholamines on rat myocardial metabolism. II. Influence of catecholamines on 32p-incorporation into rat myocardial adenylic nucleotides and their turn-over.
    Biochimie, 1975, Volume: 57, Issue:6-7

    Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Antimycin A; Caffeine; Epinephrine; Heart; Male; Myocardium; NAD; Norepinephrine; Oligomycins; Ouabain; Oxidative Phosphorylation; Phosphates; Rats; Rats, Inbred Strains; Rotenone

1975
Action of ionophore A23187 at the cellular level. Separation of effects at the plasma and mitochondrial membranes.
    The Journal of biological chemistry, 1976, Jul-10, Volume: 251, Issue:13

    Topics: Animals; Anti-Bacterial Agents; Biological Transport; Caffeine; Calcimycin; Calcium; Cattle; Cell Membrane; Male; Membranes; Mitochondria; Oxygen Consumption; Rotenone; Sperm Motility; Spermatozoa

1976
Use of NAD(P)H and flavoprotein fluorescence signals to characterize the redox state of pyridine nucleotides in epididymal bull spermatozoa.
    Biochimica et biophysica acta, 1991, Feb-08, Volume: 1056, Issue:3

    Topics: Adenine Nucleotides; Animals; Caffeine; Cattle; Cell Membrane Permeability; Cytosol; Epididymis; Flavoproteins; In Vitro Techniques; Lactates; Male; Mitochondria; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Potassium Cyanide; Pyruvates; Rotenone; Spectrometry, Fluorescence; Sperm Motility; Spermatozoa; Uncoupling Agents

1991
Antagonistic action of metabolic inhibitors on dibutyrl cyclic 3'5'-adenosine monophosphate-stimulated and caffeine-stimulated lipolysis in vitro.
    Life sciences, 1967, Apr-15, Volume: 6, Issue:8

    Topics: Adenine Nucleotides; Animals; Caffeine; Dinitrophenols; Drug Antagonism; Fatty Acids; Glycerol; In Vitro Techniques; Male; Norepinephrine; Oligomycins; Rats; Rotenone

1967
Stimulation of oxygen consumption promotes mitochondrial calcium accumulation, a process associated with, and causally linked to, enhanced formation of tert-butylhydroperoxide-induced DNA single-strand breaks.
    Experimental cell research, 1997, Nov-25, Volume: 237, Issue:1

    Topics: 3-Hydroxybutyric Acid; Caffeine; Calcium; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Catalase; DNA Damage; DNA, Single-Stranded; Electron Transport; Glucose; Glutamine; Humans; Hydrogen Peroxide; Hydroxybutyrates; Kinetics; Leukemia, Myeloid; Mitochondria; NAD; Oxygen Consumption; Peroxides; Pyruvates; Reactive Oxygen Species; Rotenone; tert-Butylhydroperoxide; Tumor Cells, Cultured

1997
NADH-Linked substrate-mediated enhancement of mitochondrial calcium accumulation and DNA single-strand breakage elicited by tert-butylhydroperoxide: the source of the cation is a ryanodine-sensitive calcium store.
    Experimental cell research, 1999, May-25, Volume: 249, Issue:1

    Topics: Caffeine; Calcium; Calcium Signaling; DNA Damage; Humans; Mitochondria; NAD; Pyruvic Acid; Rotenone; Ryanodine; tert-Butylhydroperoxide; U937 Cells

1999
Mitochondria mediate tumor necrosis factor-alpha/NF-kappaB signaling in skeletal muscle myotubes.
    Antioxidants & redox signaling, 1999,Spring, Volume: 1, Issue:1

    Topics: Amobarbital; Animals; Antimycin A; Caffeine; Ceramides; Endocannabinoids; Enzyme Inhibitors; Ethanolamines; Melitten; Mitochondria, Muscle; Muscle Development; Muscle, Skeletal; NF-kappa B; Nifedipine; Oleic Acids; Phospholipases A; Phospholipases A2; Protein Kinase C; Rats; Reactive Oxygen Species; Recombinant Proteins; Rotenone; Ruthenium Red; Signal Transduction; Tumor Necrosis Factor-alpha

1999
Functional coupling between the caffeine/ryanodine-sensitive Ca2+ store and mitochondria in rat aortic smooth muscle cells.
    The Biochemical journal, 2001, Jul-15, Volume: 357, Issue:Pt 2

    Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Caffeine; Calcium; Calcium-Transporting ATPases; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Division; Cell Membrane Permeability; Cells, Cultured; Cyclosporine; Cytosol; Endoplasmic Reticulum; Male; Mitochondria, Muscle; Models, Biological; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Rotenone; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin; Time Factors

2001
An increase in intracellular calcium concentration that is induced by basolateral CO2 in rabbit renal proximal tubule.
    American journal of physiology. Renal physiology, 2003, Volume: 285, Issue:4

    Topics: Animals; Bicarbonates; Caffeine; Calcium; Calcium Channel Blockers; Carbon Dioxide; Enzyme Inhibitors; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Membranes; Kidney Tubules, Proximal; Nifedipine; Osmolar Concentration; Rabbits; Rotenone; Thapsigargin

2003
Mitochondrial modulation of Ca2+ sparks and transient KCa currents in smooth muscle cells of rat cerebral arteries.
    The Journal of physiology, 2004, May-01, Volume: 556, Issue:Pt 3

    Topics: Animals; Bongkrekic Acid; Caffeine; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Calcium-Binding Proteins; Calcium-Transporting ATPases; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cells, Cultured; Cerebral Arteries; Clonazepam; Cyclosporine; Diltiazem; Female; Hydrogen Peroxide; Indazoles; Ion Channels; Male; Membrane Potentials; Microscopy, Confocal; Mitochondria, Muscle; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocytes, Smooth Muscle; Oligomycins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Rhodamines; Rotenone; Ruthenium Compounds; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger; Thapsigargin; Thiazepines

2004
Shear fluid-induced Ca2+ release and the role of mitochondria in rat cardiac myocytes.
    Annals of the New York Academy of Sciences, 2008, Volume: 1123

    Topics: Animals; Caffeine; Calcium; Calcium Signaling; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cyclosporine; Mitochondria, Heart; Myocardial Contraction; Myocytes, Cardiac; Rats; Rotenone; Sarcoplasmic Reticulum; Ventricular Function

2008
Role of mitochondria in modulation of spontaneous Ca2+ waves in freshly dispersed interstitial cells of Cajal from the rabbit urethra.
    The Journal of physiology, 2008, Oct-01, Volume: 586, Issue:19

    Topics: Animals; Antimycin A; Caffeine; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cells, Cultured; Central Nervous System Stimulants; Electron Transport Complex I; Electron Transport Complex III; Female; Kaempferols; Male; Membrane Potentials; Mitochondria; Muscle, Smooth; Patch-Clamp Techniques; Rabbits; Rotenone; Urethra

2008
Dose-dependent neuroprotective effect of caffeine on a rotenone-induced rat model of parkinsonism: A histological study.
    Neuroscience letters, 2016, 06-03, Volume: 623

    Topics: Animals; Brain; Caffeine; Dose-Response Relationship, Drug; Male; Neurons; Neuroprotective Agents; Parkinson Disease; Pars Compacta; Random Allocation; Rats; Rotenone

2016
Multiple AMPK activators inhibit l-carnitine uptake in C2C12 skeletal muscle myotubes.
    American journal of physiology. Cell physiology, 2017, Jun-01, Volume: 312, Issue:6

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Berberine; Biological Transport; Caffeine; Calcimycin; Calcium; Carnitine; Cell Line; Dantrolene; Enzyme Activation; Enzyme Activators; Gene Expression; Insulin; Mice; Myoblasts; Organic Cation Transport Proteins; Protein Isoforms; Ribonucleotides; Rotenone; Sodium Azide; Solute Carrier Family 22 Member 5

2017
Edaravone-caffeine combination for the effective management of rotenone induced Parkinson's disease in rats: An evidence based affirmative from a comparative analysis of behavior and biomarker expression.
    Neuroscience letters, 2019, 10-15, Volume: 711

    Topics: Animals; Antioxidants; Behavior, Animal; Biomarkers; Brain; Caffeine; Drug Synergism; Edaravone; Lipid Peroxidation; Male; Neuroprotective Agents; Oxidative Stress; Parkinsonian Disorders; Rats; Rats, Sprague-Dawley; Rotenone; Uncoupling Agents

2019
Five months of voluntary wheel running downregulates skeletal muscle LINE-1 gene expression in rats.
    American journal of physiology. Cell physiology, 2019, 12-01, Volume: 317, Issue:6

    Topics: Aging; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Caffeine; Chromatin; Chromosomal Proteins, Non-Histone; Cyclophilin A; DNA Methylation; Female; Gene Expression Regulation; Hydroxamic Acids; Long Interspersed Nucleotide Elements; Muscle Fibers, Skeletal; Muscle, Skeletal; Physical Conditioning, Animal; Primary Cell Culture; Rats; Rats, Wistar; Resveratrol; Ribonucleotides; RNA, Messenger; Rotenone; Sedentary Behavior

2019
Effects of Metformin on Spontaneous Ca
    International journal of molecular sciences, 2021, Aug-31, Volume: 22, Issue:17

    Topics: Animals; Caffeine; Calcium Signaling; Chromans; Cyclosporine; Electron Transport Complex I; Female; Hypoxia; Male; Metformin; Microglia; Mitochondria; Mitochondrial Membrane Transport Proteins; Neurons; Primary Cell Culture; Rats; Reactive Oxygen Species; Rotenone

2021
Rotenone induced olfactory deficit in Parkinson's disease rat model: The protective role of adenosine A
    Journal of chemical neuroanatomy, 2023, Volume: 127

    Topics: Animals; Brain; Caffeine; Disease Models, Animal; Male; Neuroprotective Agents; Parkinson Disease; Rats; Rats, Wistar; Rotenone

2023
Caffeine alleviates anxiety-like behavior and brainstem lesions in a rotenone-induced rat model of Parkinson's disease.
    Journal of chemical neuroanatomy, 2023, Volume: 132

    Topics: Animals; Anxiety; Caffeine; Disease Models, Animal; Dopamine; Male; Mesencephalon; Neuroprotective Agents; NF-E2-Related Factor 2; Oxidative Stress; Parkinson Disease; Rats; Rats, Wistar; Rotenone

2023